sj-docx-1-isp-10.1177_00207640241232321 – Supplemental material for Substance use and its association with mental health among Swiss medical students: A cross-sectional study

Supplemental material, sj-docx-1-isp-10.1177_00207640241232321 for Substance use and its association with mental health among Swiss medical students: A cross-sectional study by Jacques Gaume, Valérie Carrard, Sylvie Berney, Céline Bourquin and Alexandre Berney in International Journal of Social Psychiatry</p

Flowchart of participant selection for the different analyses.

<p>Abbreviations: MSM, men who have sex with men; HET, heterosexually infected person; IDU, injection drug user.</p

Numbers of patients seen in each clinical service during the four twelve-month periods studied.

<p>Abbreviations: OP, outpatients; IP, inpatients; ICU, intensive care units; ED, emergency departments.</p

HIV testing practices by clinical service and year.

<p>Figure shows the numbers of tests performed (A) and the testing rates (B) in each clinical service during each of the four twelve-month periods studied. Abbreviations: OP, outpatients; IP, inpatients; ICU, intensive care units; ED, emergency departments.</p

Logistic regression analyses of factors associated with cumulative prevalence of depression by the end of the observation period.

<p>¹P-values from logistic regression unless indicated otherwise,</p><p>² P-values from logistic regression testing for trend across groups</p><p>³ Variable has been time-updated,</p><p>⁴ Variable has been lagged for 90 days</p><p>Abbreviations: OR, Odds ratio; CI, confidence interval; PY, person years of follow-up; MSM, men who have sex with men; HET, heterosexual transmission; IDU, injection drug use; ART, antiretroviral therapy; VL, HIV viral load; HBV, hepatitis B virus; HCV, hepatitis C virus; BMI, body mass index.</p><p>Variables which correlate with IDU are omitted from the multivariable analysis.</p

The top panel shows the incidence of depression among 4,422 individuals (360 events during 9,348 person years) without depression at the first two visits since January 2010 and cumulative prevalence of depression at the last follow-up among 6756 persons seen since January 2010 (1937 events).

<p>The bottom panel displays the incidence of depression stratified by risk and age groups. Tests for trend across age groups were MSM: P = 0.004, heterosexual men: P = 0.007, and women: P = 0.53. Abbreviations: PY, person years; MSM, men who have sex with men; HET, heterosexually infected person; IDU, injection drug user.</p

Poisson regression analysis of risk for incident depression among 4,422 cohort participants free of depression at the first two baseline visits and without a history of prior psychiatric disorders.

<p>¹ P-values from Poisson regression unless indicated otherwise,</p><p>² P-values from Poisson regression testing for trend across groups</p><p>³ Variable has been time-updated,</p><p>⁴Variable has been lagged for 90 days</p><p>Abbreviations: IR, incidence rate per 100 PY; IRR, incidence rate ratio; CI, confidence interval; PY, person years of follow-up; MSM, men who have sex with men; HET, heterosexual transmission; IDU, injection drug use; ART, antiretroviral therapy; VL, HIV viral load; HBV, hepatitis B virus; HCV, hepatitis C virus; BMI, body mass index.</p><p>Variables which correlate with IDU are omitted from the multivariable analysis.</p

Percentage of tests performed with positive result, median duration of inpatient stay, mean age of all patients seen and mean age of patients tested, for each clinical service.

<p>As data were not significantly different between 2008–2009 and 2010–2011, they have been pooled for clarity.</p><p>Abbreviations: IQR, interquartile range; SD, standard deviation; N/A, not applicable; OP, outpatients; IP, inpatients; ED, emergency department.</p