Publizism in Modern Russian media: reflection and practice

The article examines the current state of publicism, are determined by its high significance in the life of society and trends. The phenomenon known today as “publicism” exists in the culture of Russia for over three centuries. However, in discussions about “publicism”, its functions, methods, forms and possibilities of continued existence, still there are ambiguities. To some extent his is due to the incompleteness of theoretical understanding of this phenomenon. This is what motivates the author of this article, a critical look at the existing theoretical understanding of “publicism” and to present a new systemic vision of this phenomenon as a more fundamental and robust phenomenon than previously thought, which is the conceptual novelty of the article and its scientific value, because it opens new directions in the study of “publicism”, the implementation of which will lead to further research to clarify its nature, forms, and types. The article also identifies the situational socio - political factors hindering the existence anddevelopment of “publicism” in the modern information space of Russia. Overcoming them will contribute to the further development of journalistic creativity

Vulvovaginal candidiasis : histologic lesions are primarily polymicrobial and invasive and do not contain biofilms

BACKGROUND: The recent demonstration of a vaginal biofilm in bacterial vaginosis and its postulated importance in the pathogenesis of recurrent bacterial vaginosis, including relative resistance to therapy, has led to the hypothesis that biofilms are crucial for the development of vulvovaginal candidiasis. The histopathology and microbial architecture of vulvovaginal candidiasis have not been previously defined; neither has Candida, containing biofilm been reported in situ. The present study aimed at clarifying the histopathology of vulvovaginal candidiasis including the presence or absence of vaginal biofilm. STUDY DESIGN: In a cross-sectional study, vaginal tissue biopsies were obtained from 35 women with clinically, microscopically, and culture-proven vulvovaginal candidiasis and compared with specimens obtained from 25 healthy women and 30 women with active bacterial vaginosis. Vaginal Candida infection was visualized using fluorescent in situ hybridization with ribosomal gene-based probes. RESULTS: Candida microorganisms were confirmed in 26 of 35 biopsies obtained from women with vulvovaginal candidiasis; however, Candida containing biofilm were not detected in any of the cases. Histopathological lesions were exclusively invasive and accompanied by co-invasion with Gardnerella or Lactobacillus species organisms. CONCLUSION: Histopathological lesions of vulvovaginal candidiasis are primarily invasive in nature and polymicrobial and do not resemble biofilms. The clinical significance of Candida tissue invasion is unknown

Submucosal Plexitis as a Predictive Factor for Postoperative Endoscopic Recurrence in Patients with Crohn's Disease Undergoing a Resection with Ileocolonic Anastomosis: Results from a Prospective Single-centre Study

Ileocolonoscopy allows early detection of recurrence after surgical resection for Crohn's disease [CD]. Plexitis, defined as presence of inflammatory cells in or around enteric ganglia or nerve bundles, in the proximal surgical margin has been associated with an increased overall recurrence risk. We investigated prospectively whether plexitis can predict endoscopic recurrence [ER] in a consecutive cohort of CD patients undergoing ileocolonic resection.status: publishe