Rates and hazard ratios of AIDS associated with eGFR from fitting a Cox regression model.

<p>^(a) Adjusted for age, gender mode of HIV transmission, ethnicity and calendar year of baseline</p><p>^(b) Adjusted for smoking, diabetes mellitus,previous AIDS diagnosis, blood pressure lowering drugs,lipid lowering drugs, total cholesterol, blood glucose levelsand high density lipoprotein cholesterol</p><p>^(c) Adjusted for ART-status, baseline CD4, CD8, nadir CD4, baseline HIV-RNA and co-infection with hepatitis B/C</p><p>^(d) Adjusted for factors in footnotes a-c.</p><p>Rates and hazard ratios of AIDS associated with eGFR from fitting a Cox regression model.</p

Risk of AIDS-events during follow-up according to basal eGFR.

<p>Risk of AIDS-events during follow-up according to basal eGFR.</p

Rates and hazard ratios of CVD associated with eGFR from fitting a Cox regression model.

<p>^(a) Adjusted for age, gender mode of HIV transmission, ethnicity and calendar year of baseline</p><p>^(b) Adjusted for smoking, diabetes mellitus,previous AIDS diagnosis, blood pressure lowering drugs,lipid lowering drugs, total cholesterol, blood glucose levelsand high density lipoprotein cholesterol</p><p>^(c) Adjusted for ART-status, baseline CD4, CD8, nadir CD4, baseline HIV-RNA and co-infection with hepatitis B/C</p><p>^(d) Adjusted for factors in footnotes a-c.</p><p>Rates and hazard ratios of CVD associated with eGFR from fitting a Cox regression model.</p

Characteristics of patients by baseline eGFR.

<p>* HCVAb+ or HBsAg+</p><p>Characteristics of patients by baseline eGFR.</p

Factors associated with risk of AIDS and/or death [a) from any cause; b) related to AIDS only] from fitting a conditional logistic regression; model using 454 to infer tropism.

<p>Factors associated with risk of AIDS and/or death [a) from any cause; b) related to AIDS only] from fitting a conditional logistic regression; model using 454 to infer tropism.</p

Risk of cerebro-cardiovascular disease during follow-up according to basal eGFR.

<p>Risk of cerebro-cardiovascular disease during follow-up according to basal eGFR.</p

Hazard ratios of AIDS from fitting a Cox regression model (other factors).

<p>Hazard ratios of AIDS from fitting a Cox regression model (other factors).</p

Hazard ratios of CCVD from fitting a Cox regression model (other factors).

<p>Hazard ratios of CCVD from fitting a Cox regression model (other factors).</p

Subjects’ characteristics according to 454 tropism determination.

<p>Subjects’ characteristics according to 454 tropism determination.</p

Probability of immune recovery (time from cART start to CD4+ count gain ≥200 cells/mmc) by Kaplan Meier estimates.

<p>Kaplan Meier estimates of the probability of achieving CD4+ T-cells count ≥200 cells/mmc from cART start according to Recent and non Recent HIV Infection; log rank test. The continuous line represents Less Recent HIV Infections (NRHI), the dot line represents Recent HIV Infections (RHI).</p