Highly viscous electron fluid in GaAs quantum wells

A fluid in which shear-stress transverse waves, being character for solids, can propagate is usually referred as a highly viscous fluid. Hydrodynamics of the fluid formed by conduction electrons has been recently discovered in graphene, ultra-pure Weyl and layered metals, and high-mobility GaAs quantum wells. Here we construct a theory of magnetotransport in a highly viscous two-dimensional (2D) electron fluid in moderate magnetic fields, accounting its viscoelastic dynamics and the memory effects in the interparticle scattering. In addition to the properties of the microwave-induced resistance oscillations (MIRO) in photoresistance explained by theories for non-interacting 2D electrons, our theory predicts an irregular shape of MIRO at certain sample sizes, a peak in photoresistance near the doubled electron cyclotron frequency, and no dependence of MIRO on the helicity of the circular polarization of radiation. These effects, which are the evidences of the excitation of the transverse magnetosonic waves, were observed in magnetotransport experiments on ultra-high-quality GaAs quantum wells. We conclude that 2D electrons in such structures in magnetic field form a highly viscous fluid.Comment: 26 pages, 10 figure

Relaxation of superflow in a network: an application to the dislocation model of supersolidity of helium crystals

We have considered the dislocation network model for the supersolid state in He-4 crystals. In difference with uniform 2D and 3D systems, the temperature of superfluid transition T_c in the network is much smaller than the degeneracy temperature T_d. It is shown that a crossover into a quasi superfluid state occurs in the temperature interval between T_c and T_d. Below the crossover temperature the time of decay of the flow increases exponentially under decrease of the temperature. The crossover has a continuous character and the crossover temperature does not depend on the density of dislocations.Comment: Corrected typo

Evaluation of the Clinical Efficacy of Prednisolone in the Treatment of Inflammatory Bowel Diseases with Different Dosage Methods

Aim: to investigate the clinical efficacy of two methods of oral dosing of prednisolone (in mg and mg/kg) for the induction of remission for patients with ulcerative colitis (UC) and Crohn's disease (CD) using the technology of constructing and evaluating the effectiveness function (dose-effect relationship).Material and methods. In this study were included 86 patients aged from 18 to 65 years with moderate or severe active inflammatory bowel disease (61 — UC, 25 — CD). All patients were treated with prednisolone at an initial daily dose from 30 to 60 mg with a subsequent tapering of dose. The clinical response to treatment was evaluated at the time of complete withdrawal of prednisolone using the generally accepted criteria. Two efficiency functions were constructed, compared and analyzed: the first — at the initial dosage of prednisolone in mg and the second calculating the dose in mg/kg of patient weight. The patients' body weight ranged from 41 to 98 kg. The “dose-effect” relationship for prednisolone was constructed with statistical transformation of the baseline clinical data and a quantitative expression of the actual doses and alternative responses into a graph of the effectiveness function. The mean value at each point was estimated based on the regression kernel scoring method.Results. Two graphs of the “dose-effect” of prednisolone in mg and mg/kg of patient weight were constructed. The optimal clinically effective dose (OCED) when calculated in mg/kg of weight was 0.70 ± 0.01 (0.68 + 0.72) mg/kg with the corresponding effect 79.25 ± 6.26 (66.62 91.88) %. When two graphs in mg and mg / kg of weight were superimposed, it is shown that when an initial dose of 40 mg is prescribed without taking into account the patient's weight, the effect of therapy will be 25 % lower. Prescribing a dose of 60 mg per day without weight will be optimal for patients with a body weight of 85-90 kg. With a lower body weight, the clinical effect will not decrease, but the likelihood of recognized side effects of prednisolone should be expected in proportion to the decrease in body weight.Conclusion. The clinical efficacy of two methods of prednisolone dosing (mg and mg/kg) for patients with IBD during the first induction course was compared.Using a new technology for constructing and evaluating the effectiveness function (dose-effect relationship) allowed us to prove a reliable relationship between the body weight of patients with the clinical effect of prednisolone in patients with UC and CD. Based on the analysis of the dose-effect relationship, the optimal clinically effective dose of prednisolone for patients with UC and CD during the first induction course was established, equal to 0.70 mg/kg, which can be recommended for use in clinical practice for calculating individual doses

Innovative development professional pedagogical education: managerial aspects

Анализируются проблемы повышения уровня инновационности российского профессионального образования, которые ставятся в современных исследованиях ученых. Авторы, выделяя сильные и слабые стороны происходящих в образовании инновационных процессов, формулируют рекомендации организационно-управленческого плана по решению сложившихся проблемThe article analyzes the problem of increasing the level of innovation of the Russian vocational training, are put in contemporary studies of scientists. The authors, highlighting the strengths and weaknesses of ongoing innovation processes in education, formulate recommendations to the organizational and management plan to address the existing problem

Application of IT in the formation of sustainable reporting of business entities

The article deals with information technologies applied in the formation of sustainable reporting of business entites and provides a review of current information solutions and their development trends. Authors analyze the current situation in the field of non-financial reporting in the Russian Federation. To improve the competitiveness of companies and industries, strengthen the business reputation of organizations, authors proposed to develop a digital platform that is cabaple to create, publish, store of non-financial reports, go through the verification process.peer-reviewe

Informed consent to medical intervention: the figure and role of a doctor

Informed consent reflects a patient’s right to decide whether to receive or refuse medical intervention. Ideally, the patient receives all the necessary information from a physician and, consciously, allows the treatment or refuses it. However, in routine practice, a doctor may influence the patient’s decision: both because of professional knowledge, and because of the very fact that a patient seeks medical help. It follows from this that voluntary basis of a patient’s consent can hardly be absolute, since a doctor often influences his decision to a greater or lesser degree. The article proposes criteria for assessing the admissibility of doctor’s influence on a patient when deciding whether to sign informed consent to medical intervention or to refuse it, using the example of cardiac surgery.

Epithets in Kazuo Ishiguro’s novel Never Let Me Go status and perspectives

The paper focuses on the analysis of the status of the epithet in the contemporary literary text of K. Ishiguro. The pertinence of the study stems from the fact that in Western linguistics, there is no tradition to consider the epithet as a distinct and independent stylistic means, and its main features have not been widely distinguished; in some cases, researchers endow the epithet with the function of the characters’ personality descriptio