1 research outputs found
Nanoscale Plasmonic Interferometers for Multispectral, High-Throughput Biochemical Sensing
In this work, we report the design, fabrication, and
characterization
of novel biochemical sensors consisting of nanoscale grooves and slits
milled in a metal film to form two-arm, three-beam, planar plasmonic
interferometers. By integrating thousands of plasmonic interferometers
per square millimeter with a microfluidic system, we demonstrate a
sensor able to detect physiological concentrations of glucose in water
over a broad wavelength range (400–800 nm). A wavelength sensitivity
between 370 and 630 nm/RIU (RIU, refractive index units), a relative
intensity change between ∼10<sup>3</sup> and 10<sup>6</sup> %/RIU, and a resolution of ∼3 × 10<sup>–7</sup> in refractive index change were experimentally measured using typical
sensing volumes as low as 20 fL. These results show that multispectral
plasmonic interferometry is a promising approach for the development
of high-throughput, real-time, and extremely compact biochemical sensors