11 research outputs found

    Search for excited quarks in the y+jet final state in proton-proton collisions at s=8 TeV

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    A search for excited quarks decaying into the γ+jet final state is presented. The analysis is based on data corresponding to an integrated luminosity of 19.7 fb −1 collected by the CMS experiment in proton–proton collisions at s=8 TeV at the LHC. Events with photons and jets with high transverse momenta are selected and the γ+jet invariant mass distribution is studied to search for a resonance peak. The 95% confidence level upper limits on the product of cross section and branching fraction are evaluated as a function of the excited quark mass. Limits on excited quarks are presented as a function of their mass and coupling strength; masses below 3.5 TeV are excluded at 95% confidence level for unit couplings to their standard model partners

    Lithium in breast milk transiently affects the renal electrolytic balance of infants

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    Background: The use of lithium during breast-feeding has not been comprehensively investigated in humans due to concerns about lithium toxicity. Procedure: We analyzed lithium in the kidneys of nursed pups of lithium medicated mothers, using analytical spectroscopy in a novel rat model. The mothers were healthy rats administered lithium via gavage (1000 mg/day Li2CO3 per 50 kg body weight). Results: Lithium was detected in the breast milk, and in the blood of pups (0.08 mM), of lithium-exposed dams at post-natal day 18 (P18), during breast-feeding. No lithium was detected after breast-feeding, at P25 (4 days after cessation of nursing). The lithium pups blood had elevated urea nitrogen at P18 and reduced total T4 at P18 and P25, indicating a longer-term effect on the kidneys and the thyroid gland. Multivariate machine-learning analysis of spectroscopy data collected from the excised kidneys of pups showed elevated potassium in lithium-exposed animals both during- and after breast-feeding. The elevated renal potassium was associated with low nephrin expression in the kidneys measured immunohistochemically during breast-feeding. After lithium exposure is stopped, the filtration of lithium from the kidneys reverses these effects. Our study showed that breastfeeding during lithium use has an effect on the kidneys of the offspring in rats

    Variations in seasonal solar insolation are associated with a history of suicide attempts in bipolar I disorder

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    Background: Bipolar disorder is associated with circadian disruption and a high risk of suicidal behavior. In a previous exploratory study of patients with bipolar I disorder, we found that a history of suicide attempts was associated with differences between winter and summer levels of solar insolation. The purpose of this study was to confirm this finding using international data from 42% more collection sites and 25% more countries. Methods: Data analyzed were from 71 prior and new collection sites in 40 countries at a wide range of latitudes. The analysis included 4876 patients with bipolar I disorder, 45% more data than previously analyzed. Of the patients, 1496 (30.7%) had a history of suicide attempt. Solar insolation data, the amount of the sun’s electromagnetic energy striking the surface of the earth, was obtained for each onset location (479 locations in 64 countries). Results: This analysis confirmed the results of the exploratory study with the same best model and slightly better statistical significance. There was a significant inverse association between a history of suicide attempts and the ratio of mean winter insolation to mean summer insolation (mean winter insolation/mean summer insolation). This ratio is largest near the equator which has little change in solar insolation over the year, and smallest near the poles where the winter insolation is very small compared to the summer insolation. Other variables in the model associated with an increased risk of suicide attempts were a history of alcohol or substance abuse, female gender, and younger birth cohort. The winter/summer insolation ratio was also replaced with the ratio of minimum mean monthly insolation to the maximum mean monthly insolation to accommodate insolation patterns in the tropics, and nearly identical results were found. All estimated coefficients were significant at p < 0.01. Conclusion: A large change in solar insolation, both between winter and summer and between the minimum and maximum monthly values, may increase the risk of suicide attempts in bipolar I disorder. With frequent circadian rhythm dysfunction and suicidal behavior in bipolar disorder, greater understanding of the optimal roles of daylight and electric lighting in circadian entrainment is needed. © 2021, The Author(s)

    Search for new physics in events with same-sign dileptons and jets in pp collisions at root s = 8 TeV (vol 01, pg 163, 2014)

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    Made available in DSpace on 2015-06-25T12:55:21Z (GMT). No. of bitstreams: 0 Previous issue date: 2015Made available in DSpace on 2015-11-26T15:18:27Z (GMT). No. of bitstreams: 2 2-s2.0-84921407514.pdf: 236271 bytes, checksum: e9b67a8637560201105108af720ed1ff (MD5) 2-s2.0-84921407514.pdf.txt: 43801 bytes, checksum: a87aa49408e3fa7bb288c13764b65c79 (MD5) Previous issue date: 20152015111

    Differential cross section measurements for the production of a W boson in association with jets in proton-proton collisions at root s=7 TeV

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    Search For New Resonances Decaying Via Wz To Leptons In Proton-proton Collisions At √s=8tev

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    Search for new physics in events with same-sign dileptons and jets in pp collisions at root s=8 TeV

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    2014

    Search for new resonances decaying via WZ to leptons in proton-proton collisions at root s=8TeV

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    A search is performed in proton-proton collisions at root s=8 TeV for exotic particles decaying via WZ to fully leptonic final states with electrons, muons, and neutrinos. The data set corresponds to an integrated luminosity of 19.5 fb -1 . No significant excess is observed above the expected standard model background. Upper bounds at 95% confidence level are set on the production cross section of a W`boson as predicted by an extended gauge model, and on the W`WZ coupling. The expected and observed mass limits for a W`boson, as predicted by this model, are 1.55 and 1.47 TeV, respectively. Stringent limits are also set in the context of low-scale technicolor models under a range of assumptions for the model parameters

    Search for physics beyond the standard model in final states with a lepton and missing transverse energy in proton-proton collisions at sqrt(s) = 8 TeV

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    see paper for full list of authorsA search for new physics in proton-proton collisions having final states with an electron or muon and missing transverse energy is presented. The analysis uses data collected in 2012 with the CMS detector, at an LHC center-of-mass energy of 8 TeV, and corresponding to an integrated luminosity of 19.7 inverse femtobarns. No significant deviation of the transverse mass distribution of the charged lepton-neutrino system from the standard model prediction is found. Mass exclusion limits of up to 3.28 TeV at a 95% confidence level for a W' boson with the same couplings as that of the standard model W boson are determined. Results are also derived in the framework of split universal extra dimensions, and exclusion limits on Kaluza-Klein W[KK,2] states are found. The final state with large missing transverse energy also enables a search for dark matter production with a recoiling W boson, with limits set on the mass and the production cross section of potential candidates. Finally, limits are established for a model including interference between a left-handed W' boson and the standard model W boson, and for a compositeness model
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