3,969 research outputs found

    Managing patients with late-onset neutropenia during treatment with ocrelizumab

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    Appellate Practice and Procedure

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    Appellate Practice and Procedure

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    Modified Adaptive Control for Region 3 Operation in the Presence of Wind Turbine Structural Modes

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    Many challenges exist for the operation of wind turbines in an efficient manner that is reliable and avoids component fatigue and failure. Turbines operate in highly turbulent environments resulting in aerodynamic loads that can easily excite turbine structural modes, possibly causing component fatigue and failure. Wind turbine manufacturers are highly motivated to reduce component fatigue and failure that can lead to loss of revenue due to turbine down time and maintenance costs. The trend in wind turbine design is toward larger, more flexible turbines that are ideally suited to adaptive control methods due to the complexity and expense required to create accurate models of their dynamic characteristics. In this paper, we design an adaptive collective pitch controller for a high-fidelity simulation of a utility-scale, variable-speed horizontal axis wind turbine operating in Region 3. The objective of the adaptive pitch controller is to regulate generator speed, accommodate wind gusts, and reduce the excitation of structural modes in the wind turbine. The control objective is accomplished by collectively pitching the turbine blades. The adaptive collective pitch controller for Region 3 was compared in simulations with a baseline classical Proportional Integrator (PI) collective pitch controller. The adaptive controller will demonstrate the ability to regulate generator speed in Region 3, while accommodating gusts, and reducing the excitation of certain structural modes in the wind turbine

    Augmented Adaptive Control of a Wind Turbine in the Presence of Structural Modes

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    Wind turbines operate in highly turbulent environments resulting in aerodynamic loads that can easily excite turbine structural modes, potentially causing component fatigue and failure. Two key technology drivers for turbine manufacturers are increasing turbine up time and reducing maintenance costs. Since the trend in wind turbine design is towards larger, more flexible turbines with lower frequency structural modes, manufacturers will want to develop methods to operate in the presence of these modes. Accurate models of the dynamic characteristics of new wind turbines are often not available due to the complexity and expense of the modeling task, making wind turbines ideally suited to adaptive control. In this paper, we develop theory for adaptive control with rejection of disturbances in the presence of modes that inhibit the controller. We use this method to design an adaptive collective pitch controller for a high-fidelity simulation of a utility-scale, variable-speed wind turbine operating in Region 3. The objective of the adaptive pitch controller is to regulate generator speed, accommodate wind gusts, and reduce the interference of certain structural modes in feedback. The control objective is accomplished by collectively pitching the turbine blades. The adaptive pitch controller for Region 3 is compared in simulations with a baseline classical Proportional Integrator (PI) collective pitch controller

    Reduction of a metapopulation genetic model to an effective one island model

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    We explore a model of metapopulation genetics which is based on a more ecologically motivated approach than is frequently used in population genetics. The size of the population is regulated by competition between individuals, rather than by artificially imposing a fixed population size. The increased complexity of the model is managed by employing techniques often used in the physical sciences, namely exploiting time-scale separation to eliminate fast variables and then constructing an effective model from the slow modes. Remarkably, an initial model with 2D\mathcal{D} variables, where D\mathcal{D} is the number of islands in the metapopulation, can be reduced to a model with a single variable. We analyze this effective model and show that the predictions for the probability of fixation of the alleles and the mean time to fixation agree well with those found from numerical simulations of the original model.Comment: 16 pages, 4 figures. Supplementary material: 22 pages, 3 figure

    Intrinsic noise and discrete-time processes

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    A general formalism is developed to construct a Markov chain model that converges to a one-dimensional map in the infinite population limit. Stochastic fluctuations are therefore internal to the system and not externally specified. For finite populations an approximate Gaussian scheme is devised to describe the stochastic fluctuations in the non-chaotic regime. More generally, the stochastic dynamics can be captured using a stochastic difference equation, derived through an approximation to the Markov chain. The scheme is demonstrated using the logistic map as a case study.Comment: Modified version accepted for publication in Phys. Rev. E Rapid Communications. New figures adde

    Inter- and intra-specific variation in accumulation of cadmium by peanut, soybean, and navybean

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    Production of summer grain legumes like peanut, soybean, and navybean is expanding into irrigated or high rainfall areas on more acid, lighter textured soils in coastal areas of north-eastern Australia. A history of intensive use of phosphatic fertilisers, combined with soil properties which generally enhance phytoavailability of cadmium (Cd), have produced concerns about the likely quality of grain legumes produced in these areas. This paper reports field and pot experiments which examine the effect of grain legume species and variety on Cd accumulation when grown across a range of soil types. Results clearly show that both peanut and soybean accumulate Cd in seeds at levels greater than the maximum permitted concentration (MPC, 0·05 mg Cd/kg) even on soils with relatively low total or available Cd concentrations ( soybean > navybean, with the differences between peanut and navybean apparently correlated with differences in total plant Cd uptake. Cadmium concentrations in plant tops always exceeded that in seeds or kernel, and the testa in peanut kernel was shown to contain Cd concentrations that were 50 times greater than that in the embryonic axis and cotyledons. Significant (P < 0·05) variation in Cd content (at least 2-fold) was recorded among peanut varieties, with lesser variation evident among a limited sample of commercial navybean varieties. Comparison of results for 11 peanut varieties grown at each of 2 locations suggested strong genotype environment interactions determining kernel Cd concentration. Highly significant (P < 0·01) linear relationships were established between soil Cd in the cultivated layer (0-20 cm; 0·1 M CaCl2 extraction) and seed Cd content in field-grown soybean. However, despite observations of an apparent relationship between soil Cd (CaCl2 extraction) and peanut kernel Cd in pot studies, relationships between soil Cd in the cultivated layer and kernel Cd could not be reproduced in field trials. Kernel Cd concentrations from field-grown peanut plants were generally higher than those from pot trials, despite using soil collected from the cultivated layer (0-20 cm) of the field site for the potting medium. The presence of significant levels of Cd to approximately 60 cm in the soil profile and a general decline in pHw with depth suggest the lack of correlation between soil test Cd in the top 20 cm and kernel Cd in field-grown plants may be at least partly due to Cd uptake from deeper soil layers
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