An Investigation of the Relationship Between Social Entrepreneurship Levels of Pre-Service Primary School Teachers and Their Social Values

This study seeks to investigate the relationship between social entrepreneurship levels of pre-service primary school teachers and their social values. The research was designed in descriptive survey model. The research was conducted with the participation of 488 pre-service primary school teachers. “Social Entrepreneurship Scale” developed by Konaklı and Göğüş (2013) and “Multi-dimensional Social Values Scale” developed by Bolat (2013) were used as the data collection tools. The data were analyzed through descriptive statistics and t-test while the unrelated samples were analyzed through one-way analysis of variance. Also, the relationship between the variables was analyzed by using regression analysis. The results of the analyses reveal that there is a statistically significant difference among the pre-service primary school teachers’ social entrepreneurship and social values scale scores in terms of the variables of gender and class. When the rest of the variables are considered, there is a statistically insignificant difference among the scores.  The relationship between social entrepreneurship levels of the participants and their social values scores is statistically significant. The social entrepreneurship score of an individual and their social values score are correlated. As the social entrepreneurship score increases, so does the score of social values. When one analyzes – by using regression coefficient – the level of impact social entrepreneurship creates on the variable of social values; in other words, how definable the social values become by means of social entrepreneurship, it can be observed that there is a medium-level variability, i.e., social entrepreneurship is a medium-level significant predictor of social values. Keywords: Social Entrepreneurship, Social Values, Primary School Teachers, Pre-Service Teacher

Forecasting The Exchange Rate Series With Ann: The Case Of Turkey

As it is possible to model both linear and nonlinear structures in time series by using Artificial Neural Network (ANN), it is suitable to apply this method to the chaotic series having nonlinear component. Therefore, in this study, we propose to employ ANN method for high volatility Turkish TL/US dollar exchange rate series and the results show that ANN method has the best forecasting accuracy with respect to time series models, such as seasonal ARIMA and ARCH models. The suggestions about the details of the usage of ANN method are also made for the exchange rate of Turkey.Activation function, ARIMA, ARCH, Artificial neural network, Chaotic series, Exchange rate, Forecasting, Time series

Metaforinis būsimųjų geografijos mokytojų sąvokos „geografija“ suvokimo vertinimas

This study was carried out to reveal the metaphors by geography teacher candidates about the concept of “Geography.” The data of the study were collected with qualitative research method and the study was carried out on the pattern of phenomenology. The data were subjected to content analysis. In order to determine the students’ perceptions about the concept of geography, a semistructured form was prepared, and this form included the sentence of “Geography is like a/an ..........., because ........” Students were asked to complete this sentence in the form. When the findings of the study were evaluated, it was seen that 86 valid metaphors had been produced by the students. These metaphors were coded in terms of their common features and 8 different conceptual categories were created. The prominent ones of these categories were “Geography as the source of discovery and learning,” “Geography as the source of diversity,” “Geography as similar to humanity,” “Geography as the source of peace and acceptance,” and metaphor numbers and frequencies of these categories were high.Straipsnyje pristatomu tyrimu siekiama atskleisti, kokias metaforas sąvokai „geografija“ taiko būsimieji geografijos mokytojai. Tyrime taikyta kokybinio fenomenologinio metodo prieiga, atlikta duomenų turinio analizė. Siekiant ištirti tyrime dalyvavusių studentų geografijos sąvokos suvokimą, buvo parengta pusiau struktūruota forma, į ją įtrauktas sakinys: „Geografija yra kaip ..........., nes ........“, ir studentų buvo paprašyta užpildyti šį sakinį formoje. Tyrimo radiniai atskleidė, kad studentai pateikė 86 validžias metaforas. Metaforos buvo koduojamos pagal bendrus bruožus, sukurtos 8 konceptualios kategorijos. Iš jų labiausiai išsiskiria šios: „Geografija kaip atradimų ir mokymosi šaltinis“, „Geografija kaip įvairovės šaltinis“, „Geografija kaip tai, kas panašu į žmoniją“, „Geografija kaip taikos ir pripažinimo šaltinis“ – visos šios kategorijos išsiskyrė metaforų skaičiumi ir dažnumu

Synthesis of novel dopamine derived multidirectional ligands from cyanuric chloride: structural and antimicrobial studies

Two monopodal (2,4-dichloro-6-(3-hydroxytyramine)-1,3,5-triazine) and tripodal (2,4,6-(3-hydroxytyramine)-1,3,5-triazine) s-triazine derivatives were prepared through the reaction of cyanuric chloride (2,4,6-trichloro-1,3,5-triazine) and 3-hydroxytyramine hydrochloride (do-pamine hydrochloride). The structures of the compounds were identified by FT-IR, 1H NMR, 13C NMR, thermal analysis and elemental analysis. Their antimicrobial activities were car-ried out using the broth microdilution method in dimethyl sulfoxide (DMSO): Phosphate Buffered Saline (PBS) against eight bacteria and one yeast. The results of the test were com-pared with ampicillin. It was determined that CCDOP1, CCDOP3 and DOP have significant antibacterial and antifungal activity. These three chemicals revealed strong antibacterial activ-ity against the E. coli and S. aureus strains used in the study. S. aureus was the most sensitive strain against dopamine hydrochloride and E. coli was the most sensitive bacteria against CCDOP1

Association of heart rate recovery with microalbuminuria in non-obstructive coronary artery disease

Background: Non-obstructive coronary artery disease (CAD) is associated with significantly increased risk for myocardial infarction. Heart rate recovery (HRR), a measure of autonomic function, is a strong predictor of all-cause mortality. Microalbuminuria, a marker of early arterial disease, is an independent risk factor for cardiovascular disease and mortality. We aimed to investigate HRR and determine its relationship with microalbuminuria in patients with non-obstructive CAD.Methods: We prospectively studied 565 patients who underwent elective coronary angiography. All participants underwent urinary analysis and then an exercise test. Microalbuminuria was defined as an urinary albumin-to-creatinine ratio (UACR) of 30 -299 mg/g. The HRR was abnormal if 12 beats/min, n = 439).Results: Patients with microalbuminuria had lower HRR and patients with lower HRR had higher UACR. While UACR was negatively correlated with HRR in patients with microalbuminuria (r = -0.424; P < 0.001) and in patients with lower HRR (r = -0.192; P = 0.042), there was no correlation of UACR with HRR in neither patients with normoalbuminuria nor patients with higher HRR, respectively. In the all study population, there was a significant inverse association between UACR and HRR (r = -0.445, P < 0.001), and UACR independently predicted the presence of lower HRR (P < 0.001).Conclusions: Our findings showed that there was a significant inverse association between UACR and HRR in patients especially with microalbuminuria, and that albuminuria might predict cardiac autonomic imbalance evaluated by HRR in patients with non-obstructive CAD

Viscosity of carbon nanotubes water based nanofluids: Influence of concentration and temperature

International audienceExperimental results on the steady-state viscosity of carbon nanotubes water-based nanofluids are presented considering the influence of particle volume fraction and temperature ranging from 0 to 40 C. The suspensions consist of multi-walled carbon nanotubes dispersed in de-ionized water and they are stabilized by a surfactant. The aspect ratio of nanotubes is close to 160 and the particle volume fraction varies between 0.0055% and 0.55%. It is shown that the nanofluids behave as shear-thinning materials for high particle content. For lower particle content, the nanofluids are quite Newtonian. It is also observed that the relative viscosity of nanofluids at high shear rate does not vary with temperature. Moreover, the evolution of relative viscosity at high shear rate is well predicted by the Maron-Pierce model considering the effect of nanoparticles agglomerates

Siyasal İletişimde Kadın: Canvassing Modeli Üzerine Değerlendirme

Günümüzde kadının siyasal hayattaki rolü, geçmişe oranla artmış olsa da güncel veriler değerlendirildiğinde siyasal katılım oranlarının düşüklüğü dikkat çekmektedir. Kadının siyasal hayattaki rolünü arttırmak ve bu yönde hedeflerin gerçekleştirilmesini sağlamak siyasal hayatın gelişmesi açısından oldukça önemlidir. Propaganda faaliyetleri, geçmişten günümüze değişim ve dönüşüm yaşamışken siyasi partilerin politikaları ve adayların kullanacakları tekniklerin yarattığı etkiler oldukça önemlidir. Propaganda teknikleri, teknolojinin gelişimi ve siyasal iletişimde kullanılan araçlarda yaşanan değişiklikler ile bağlantılı olarak değişmiştir. Geleneksel teknikler ve yeni teknikler üzerine bir analiz yapmak, hangi tekniklerin adaylara daha fazla fayda sağlayacağını ortaya koymak adına önem arz etmektedir. Çalışmanın asıl gayesi, günümüzde siyasal katılımı ve oy oranlarını artırmaya yönelik girişimlerden eski bir teknik olan Canvassing(yüz yüze oy toplama) yönteminin seçmen davranışlarını etkileme sürecinde daha etkili olduğu varsayımından hareketle, seçmenleri oy vermeye ikna yöntemi olarak Canvassing modelini kadınların yönetmesiyle, hedefe ulaşma konusunda sağlayabileceği katkıları ortaya koymaktır. Araştırmada TBMM’nde bulunan partilerin Adana ili sınırları içerisinde yer alan kadın kolları temsilcileri örneklem olarak belirlenmiştir. Partilerin propaganda faaliyetleri ve Canvassing(yüz yüze oy toplama) yönteminden aldıkları geri dönüşler irdelenmiştir. Araştırmada Canvassing(yüz yüze oy toplama) yönteminin yeni tekniklere göre daha etkili sonuçlar doğurduğu ve aynı zamanda kadınların bu tekniği kullanmasıyla beraber oy oranlarında artış yaratarak seçmeni etkileme, ikna etme açısından olumlu katkı sağladığı sonucuna ulaşılmıştır

Rupture of Stochastically Occurring Vesicle Clusters Limits Bilayer Formation on Alkane-PEG-Type Supports:Uncoupling Clustering from Surface Coverage

Polymer-supported bilayers (PSBs) are a recognized tool for drug discovery through function-interaction analysis of membrane proteins. While silica-supported bilayers (SSBs) spontaneously form from surface-adsorbed vesicles, successful PSB formation via a similar method has thus far been limited by an insufficient understanding of the underlying vesicle-remodelling processes. Here, we generated a polymer support through the incubation of poly-l-lysine conjugated to alkyl-chain-terminated poly­(ethylene)­glycol on silica. This polymer-coated silica substrate yielded efficient vesicle adsorption and spontaneous bilayer formation, thereby providing a rare opportunity to address the mechanism of PSB formation and compare it to that of SSB. The combined use of super-resolution imaging, kinetics, and simulations indicates that the rupture of stochastically formed vesicle clusters is the rate-limiting step, which is an order of magnitude higher for silica than for polymer-coated silica. This was confirmed by directly demonstrating increased rupture rates for surface adsorbed multivesicle assemblies formed by vesicle cross-linking in solution. On the basis of this key insight we surmised that a low propensity of cluster rupture can be compensated for by an increase in the number density of clusters: the deposition of a mixture of oppositely charged vesicles resulted in bilayer formation on another alkane–PEG type of interface, which despite efficient vesicle adsorption otherwise fails to support spontaneous bilayer formation. This potentially provides a universal strategy for promoting bilayer formation on resistant surfaces without resorting to modifying the surface itself. Therefore, multivesicle assemblies with tailored geometries not only could facilitate bilayer formation on polymers with interesting functional properties but also could instigate the exploration of vesicle architecture for other processes involving vesicle remodelling such as drug delivery

Experimental investigations of the viscosity of nanofluids at low temperatures

Special Issue on Energy Solutions for a Sustainable World - Proceedings of the Third International Conference on Applied Energy, May 16-18, 2011 - Perugia, Italy Guest Editors: Umberto Desideri, Jinyue YanInternational audienceThe effects due to temperature and shearing time on viscosity for Al2O3/water and CNT/water based nanofluids at low concentration and low temperatures are experimentally investigated. The viscosity data were collected using a stress-controlled rheometer equipped with parallel plate geometry under up and down shear stress ramp. CNT and Al2O3 water based nanofluids exhibited hysteresis behaviour when the stress is gradually loaded and unloaded, depending also on shearing time. Experiments also showed that the nanofluid suspensions indicated either Newtonian or non-Newtonian behaviour, depending on shear rate. CNT water based nanofluid behaves as Newtonian fluid at high shear rate whereas Al2O3 water based nanofluid is non-Newtonian within the range of low temperatures investigated

The non-structural protein 5A (NS5A) of hepatitis c virus interacts with the SH3 domain of human Bin1 using non-canonical binding sites

The hepatitis C virus (HCV) is a major human pathogen that causes severe diseases such as chronic hepatitis, liver cirrhosis and finally hepatocellular carcinoma. Although no enzymatic activity could be attributed yet to the HCV non-structural protein 5A (NS5A), it is indispensable for viral replication and particle assembly. Furthermore, it is associated with a variety of cellular pathways, although their relevance for viral pathogenesis still has to be elucidated. To fulfil its function NS5A interacts with a large number of different proteins including both viral and human ones. NS5A is organized into three domains, which are connected via two low complexity sequences (LCS). The first domain is highly conserved among different HCV genotypes and forms a well-defined globular structure [1]. The domains 2 (D2) and 3 (D3) are less conserved and intrinsically disordered. Nonetheless, three segments in LCS-I and D2 show significant propensities to adopt a-helical structures as could be shown by nuclear magnetic resonance (NMR) chemical shift and 15 N relaxation data [2]. The LCS-II connecting D2 and D3 contains two directly neighbored class II PxxP-motifs, which are important for interactions with Src homology 3 (SH3) domains. SH3 domains mediate protein-protein interactions, often via binding to polyproline II helices. Recent studies also revealed alternative binding mechanisms, mainly involving helical motifs and positively charged amino acid residues. The SH3 domain of the bridging integrator 1 (Bin1) is known to interact with NS5A not only via its PxxP-motifs, but also via two non-canonical binding sites, which will be further described here [3]