582 research outputs found
Evaluating the effects of management on territorial populations using Swarm
For centuries, coyotes have been controlled to protect livestock and/or enhance game populations. The intensity of control has varied widely and many types of control techniques have been used. The effects of these control techniques need to be evaluated to effectively resolve conflicts among agencies and interest groups, to fulfill legal requirements, and to aid the development of new strategies for managing populations. However, the influence of these techniques on coyote population size and structure is largely unknown. Furthermore, management decisions are often required before experimental tests can be developed and conducting requisite experimental programs on meaningful scales are logistically prohibitive. Therefore, we developed an individual-based computer model using Swarm to evaluate the effects of various control techniques on age structure including selective removal, random removal, and denning. This model is part of a larger effort to fully evaluate the effect of current management strategies on coyote populations and to eventually link this population model to a depredation model. Selective and random removal resulted in younger age structures, whereas denning produced population age structures similar to an unexploited population
Non-Invasive Prenatal Genetic Testing (NIPT) Leading to Prenatal Diagnosis of Trisomy 21 Mosaicism and 18q Deletion Syndrome: Two Cases
NIPT is non-definitive testing to estimate the possibility that fetuses have trisomy 21, trisomy 18, or trisomy 13. However, in NIPT-positive and indeterminate cases, rare chromosomal disease may become apparent, requiring advanced genetic considerations and counseling skills. We experienced two such cases, a trisomy 21 mosaicism case triggered by NIPT-positive status and 18q deletion syndrome triggered by NIPT-indeterminate status. These cases have two clinical implications for NIPT. First, it was revealed that trisomy mosaicism might be found in NIPT-positive cases that have lower Z-Scores than those inferred from the fraction of fetal cfDNA in the case of standard trisomy. Second, it is possible that microdeletion syndrome could be the reason for an indeterminate NIPT result. Today’s genetic counseling requires more expertise in ethics and communication as well as genetic science because NIPT can lead to totally unexpected results
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