13 research outputs found

    <span style="font-size:14.0pt;font-family:"Times New Roman";color:#141414;mso-bidi-font-weight: bold" lang="EN-IN">Synthesis and antibacterial activities of some fluorine containing <span style="font-size:14.0pt;line-height:115%;font-family:"Times New Roman"; mso-fareast-font-family:"Times New Roman";color:#141414;mso-ansi-language:EN-IN; mso-fareast-language:EN-IN;mso-bidi-language:HI;mso-bidi-font-weight:bold" lang="EN-IN">arylfurylpropenones, pyrazolines and <i>N- </i>acetylpyrazoline</span></span>

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    440-447Several fluorine containing arylfurylpropenones 3 have been synthesized starting from arylfurfurals 1 and 2,4-dichloro-5- fluoroacetophenone 2. These arylfurylpropenones are then used for the synthesis of fluorine containing arylfurylpyrazolines 4.The newly synthesized pyrazolines are then converted into their N-acetyl derivatives 5. The structures of these compounds have been confirmed on the basis of elemental analysis, IR, NMR and mass spectral studies. The mechanism for the formation of pyrazolines has been investigated. The above compounds are also subjected to antibacterial screening. Their minimal inhibitory concentration <span style="font-size:14.0pt;line-height:115%;font-family: " times="" new="" roman";mso-fareast-font-family:"times="" roman";color:#393939;="" mso-ansi-language:en-in;mso-fareast-language:en-in;mso-bidi-language:hi"="" lang="EN-IN">(MIC) values indicate that some of these compounds exhibit <span style="font-size:14.0pt;line-height:115%; font-family:" times="" new="" roman";mso-fareast-font-family:"times="" roman";="" color:#393939;mso-ansi-language:en-in;mso-fareast-language:en-in;mso-bidi-language:="" hi"="" lang="EN-IN">exce<span style="font-size:14.0pt;line-height:115%; font-family:" times="" new="" roman";mso-fareast-font-family:"times="" roman";="" color:#141414;mso-ansi-language:en-in;mso-fareast-language:en-in;mso-bidi-language:="" hi"="" lang="EN-IN">ll<span style="font-size:14.0pt;line-height:115%; font-family:" times="" new="" roman";mso-fareast-font-family:"times="" roman";="" color:#393939;mso-ansi-language:en-in;mso-fareast-language:en-in;mso-bidi-language:="" hi"="" lang="EN-IN">ent <span style="font-size:14.0pt;line-height:115%; font-family:" times="" new="" roman";mso-fareast-font-family:"times="" roman";="" color:#262626;mso-ansi-language:en-in;mso-fareast-language:en-in;mso-bidi-language:="" hi"="" lang="EN-IN">antibacterial <span style="font-size:14.0pt;line-height: 115%;font-family:" times="" new="" roman";mso-fareast-font-family:"times="" roman";="" color:#393939;mso-ansi-language:en-in;mso-fareast-language:en-in;mso-bidi-language:="" hi"="" lang="EN-IN">ac<span style="font-size:14.0pt;line-height:115%; font-family:" times="" new="" roman";mso-fareast-font-family:"times="" roman";="" color:#141414;mso-ansi-language:en-in;mso-fareast-language:en-in;mso-bidi-language:="" hi"="" lang="EN-IN">tivities

    Synthesis of pyrazolines promoted by Amberlyst-15 catalyst

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    568-571The condensation of a series of aromatic ketones with aromatic aldehydes under aldol conditions affords 1-aryl-3-(substituted­phenyl/phenyl furanyl/thienyl)-2-propen-1-ones 1. The resulting propenones undergo facile and clean cyclization with hydrazine and substituted hydrazine derivatives to yield 3-aryl-5-(substituted­phenyl/phenylfuranyl/thienyl)-2-pyrazolines 2. This reaction is carried out in the presence of Amberlyst–15 catalyst to afford the above pyrazolines 2 in considerably good yield. All the synthesized compounds have been characterized by spectral studies

    Bivalve mollusk assemblages on São Paulo's northern continental shelf, southeast Brazil

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    Soft bottom bivalve mollusc assemblages were sampled along a depth gradient (10 to 100 m) on the northern São Paulo shelf during the austral summer and winter. A one-way analysis of similarity permutation test revealed there was no seasonal difference in the structure of the bivalve assemblages in the area. A clustering analysis indicated 3 groups of stations corresponding to the bathymetric gradient. Both K-dominance curves and Shannon and Pielou indexes showed higher biological diversity and higher evenness for the shallower area. Most of the bivalves found were classified as suspension-feeders, co-occurring with deposit-feeder species, suggesting an absence of negative interactions between these trophic groups. Differences in the frequency of disturbance along the depth gradient caused by wave storms - more common in winter - and also by predation and anthropogenic activities, such as dredging of fishing boats and input of gross sewage, likely explain the higher diversity found on the inner shelf of Ubatuba
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