Learning Robust Representations via Multi-View Information Bottleneck

This is the author accepted manuscript.The information bottleneck method (Tishby et al. 2000) provides an information theoretic method for representation learning, by training an encoder to retain all information which is relevant for predicting the label, while minimizing the amount of other, superfluous information in the representation. The original formulation, however, requires labeled data in order to identify which information is superfluous. In this work, we extend this ability to the multi-view unsupervised setting, in which two views of the same underlying entity are provided but the label in unknown. This enables us to identify superfluous information as that which is not shared by both views. A theoretical analysis leads to the definition of a new multi-view model which produces state-of-the-art results on the Sketchy dataset and on label-limited versions of the MIR-Flickr dataset. We also extend our theory to the single-view setting by taking advantage of standard data augmentation techniques, empirically showing better generalization capabilities when compared to traditional unsupervised approaches for representation learning.European Union Horizon 202

Evaluation of complementary use of organic manure for sustainable water yam production in Uyo, southeastern Nigeria

A two year study was conducted at University of Uyo Teaching and Research Farm, Use Offot, Uyo, Akwa Ibom State in 2009 and 2010 cropping seasons to assess the effects of complementary use of different organic manures on water yam growth and yield, economic returns to management as well as attack by some pests . The experiment was laid out in a randomized complete block design with three replicates. There were 8 fertilizer treatments viz: poultry manure (PM), goat manure (GM), and oil palm bunch ash (OPBA) each at 20 tha-1 , OPBA + PM, OPBA + GM and PM + GM each at a ratio of 1:1 (10 tha-1 + 10 tha-1), NPK (15:15:15) at 400 kgha-1 ( a recommended dose of inorganic fertilizer) and control (no soil amendment). Results showed significant differences on vegetative traits, number of days to senescence and yield and yield components of water yam. Treatments that received complementary application of PM + GM produced the highest tuber yield (26.15 and 27.96 tha-1 in 2009 and 2010, respectively with corresponding cost- benefit ratios of 14.17 and 15.49,respectively) followed by complementary use of OPBA + PM, (24.22 and 27.03 tha-1,respectively). The use of inorganic fertilizer (NPK - 15:15:15) produced 22.60 and 23.81 tha-1 of yam tuber with a corresponding cost -benefit ratio of 11.02 and 10.88 in 2009 and 2010, respectively .All organic manure based treatments had no symptom of termite and yam beetle attack. This study indicates strongly the potentials of complementary use of organic manures for sustainable water yam production in Uyo, southeastern Nigeria. Keywords: organic manures, complementary use, water ya

TRITIUM, HYDROGEN AND OXYGEN ISOTOPE COMPOSITIONS IN MONTHLY PRECIPITATION SAMPLES COLLECTED AT TOKI, JAPAN

Monthly precipitation samples have been collected at Toki, Japan, from November 2013 to March 2017. In this report, selected data were analysed to identify the regional hydrogen and oxygen isotope compositions. Tritium (3H) concentration in the precipitation ranged from 0.10 to 0.61 Bq L−1 and higher 3H concentrations were observed in spring rather than in other seasons. This range was similar to values reported in Chiba City, Japan. 3H concentration and the ratio d-excess, and δD values were roughly clustered according to each separate season. These regional hydrogen and oxygen isotope compositions will be used for environmental assessments of effects of the deuterium plasma experiments of the large fusion test device

Effects of Complementary use of Organic and Inorganic fertilizers on the growth and yield of Cucumber (Cucumu sativus. L.) on an ultisol

A field study was conducted in 2008 and 2009 early cropping seasons to assess the response of cucumber (Cucumus sativus L.) to complementary use of organic and inorganic fertilizers in Uyo agro-ecology. The fertilizer treatments were: NPK (15:15:15) at 100 and 200 kgha-1, poultry manure (PM) at 5 and 10 tha-1 , and complementary application of 100 kgha-1 of NPK + 5 tha-1 of PM, 100 kgha-1 of NPK + 10 tha-1 of PM, 200 kgha1 of NPK +5 tha-1 of PM ,200 kgha-1 of NPK +10 tha-1 of PM and control (no fertilizer). Results showed significant differences (P<0.05) in all the growth and yield parameters considered in both cropping seasons. The combined application of 200 kgha-1 of NPK and 10 tha-1 of PM performed better than sole application of either organic or inorganic fertilizer, with fresh fruit yield of 14.63 and 14.92 tha-1 in 2008 and 2009, respectively and exceeded other treatments by 1 -76% and 1-73% in 2009 and 2010, respectively. This indicates strongly the synergistic benefits of using both organic and inorganic fertilizers even at lower rates

Proton density fat fraction: magnetic resonance imaging applications beyond the liver

Magnetic resonance imaging-proton density fat fraction (MRI-PDFF) is an emerging quantitative imaging biomarker that accurately measures the fat fraction of tissue by correcting factors influencing magnetic resonance signal intensity. Beyond fat quantification, it also measures R2* which is a direct measure of iron concentration. The utilization of MRI-PDFF in liver diseases is well established. In the present review, we focused on applications of MRI-PDFF in different body areas including pancreas, bone, muscle, spleen, testis, visceral, and subcutaneous adipose tissue. Future studies can enable tracking of quantitative fat fraction changes in different organs simultaneously, which can be critical in understanding fat metabolism

COMBINING ABILITY AND HETEROTIC PATTERN IN WEST AFRICAN SORGHUM LANDRACES

Heterotic grouping based on combining ability for traits of interest, in addition to plant performance and genetic relationship among germplasm, would be useful in planning crosses in breeding programmes. This study aimed at determining the combining abilities of selected landraces for morphological and physiological traits under contrasted environments and identifying the suitable heterotic grouping method for superior hybrid production. For this purpose, nineteen accessions representing different origins and population structure among West African Sorghum Accessions Panel (WASAP) and two female lines, were used in \uab\ua0Line x tester\ua0\ubb mating design to produce thirty-eight (38) hybrids. Analysis of variance showed significant general combining ability and specific combining ability effects for grain weight, plant height, days to flowering, panicle length and chlorophyll content implying existence of heterotic responses for these traits. Both additive and non-additive gene effects were important in controlling the inheritance of the traits. Parents K31.3, K37 and Ni331 were the best combiners for grain weight, providing the opportunity for breeders to improve grain yield under diverse environments. AVG-1 x K31.3 and AVG-1 x Tg148 were the superior hybrids. Combining ability based heterotic grouping methods classified sorghum accessions into four groups. The heterotic group\u2019s specific and general combining ability (HSGCA) method was the suitable in predicting hybrid superiority. This combining abilities based heterotic grouping study is an additional tool that breeders could use to identify the best parents for superior hybrids development in West Africa.La d\ue9termination des groupes h\ue9t\ue9rotiques bas\ue9e sur les aptitudes \ue0 la combinaison des traits d\u2019int\ue9r\ueat en plus des performances et des relations g\ue9n\ue9tiques dans une collection est importante pour planifier les croisements en s\ue9lection. Cette visait la d\ue9termination des aptitudes \ue0 la combinaison des accessions locales pour certains traits morphologiques sous environnements contrast\ue9s et l\u2019identification de la meilleure m\ue9thode dans la pr\ue9diction de la vigueur hybride. Dans cette perspective, dix-neuf accessions repr\ue9sentant diff\ue9rentes origines et la structure de la population d\u2019un panel ouest africain de sorgho (WASAP) et deux m\ue2les st\ue9riles ont \ue9t\ue9 utilis\ue9s dans un croisement \uab\ua0Line x tester\ua0\ubb pour produire trente-huit hybrides F1, objet de cette \ue9tude. L\u2019analyse de variance a indiqu\ue9 des effets significatifs de l\u2019aptitude g\ue9n\ue9rale et sp\ue9cifique \ue0 la combinaison pour le poids grain, la hauteur plante, la dur\ue9e semis floraison et la concentration en chlorophylle traduisant l\u2019existence des r\ue9ponses h\ue9t\ue9rotiques pour ces traits. Les effets g\ue9niques additif et non-additif ont \ue9t\ue9 importants dans le contr\uf4le de ces caract\ue8res. K31.3, K37 et Ni331 pr\ue9sentent les meilleures aptitudes g\ue9n\ue9rales \ue0 la combinaison puis AVG-1 x K31.3 et AVG-1 x Tg148 ont \ue9t\ue9 les meilleurs hybrides pour le poids grains. Ils constituent une opportunit\ue9 pour l\u2019am\ue9lioration dans divers environnements. Les diff\ue9rentes m\ue9thodes ont class\ue9 les accessions de sorgho en quatre groupes. Le groupage bas\ue9 sur la m\ue9thode HSGCA accroit l\u2019efficience en s\ue9lection de 15 %. Cette \ue9tude offre un outil d\u2019aide pour les s\ue9lectionneurs dans le choix des meilleurs parents \ue0 croiser pour la production des hybrides sup\ue9rieurs en Afrique de l\u2019Ouest

Multi-Target Prediction: A Unifying View on Problems and Methods

Multi-target prediction (MTP) is concerned with the simultaneous prediction of multiple target variables of diverse type. Due to its enormous application potential, it has developed into an active and rapidly expanding research field that combines several subfields of machine learning, including multivariate regression, multi-label classification, multi-task learning, dyadic prediction, zero-shot learning, network inference, and matrix completion. In this paper, we present a unifying view on MTP problems and methods. First, we formally discuss commonalities and differences between existing MTP problems. To this end, we introduce a general framework that covers the above subfields as special cases. As a second contribution, we provide a structured overview of MTP methods. This is accomplished by identifying a number of key properties, which distinguish such methods and determine their suitability for different types of problems. Finally, we also discuss a few challenges for future research

Role of potassium and calcium channels in sevoflurane-mediated vasodilation in the foeto-placental circulation

<p>Abstract</p> <p>Background</p> <p>Sevoflurane has been demonstrated to vasodilate the foeto-placental vasculature. We aimed to determine the contribution of modulation of potassium and calcium channel function to the vasodilatory effect of sevoflurane in isolated human chorionic plate arterial rings.</p> <p>Methods</p> <p>Quadruplicate <it>ex vivo </it>human chorionic plate arterial rings were used in all studies. <b><it>Series 1 and 2 </it></b>examined the role of the K⁺channel in sevoflurane-mediated vasodilation. Separate experiments examined whether tetraethylammonium, which blocks large conductance calcium activated K⁺(K_Ca++) channels (<b><it>Series 1A+B</it></b>) or glibenclamide, which blocks the ATP sensitive K⁺(K_ATP) channel (<b><it>Series 2</it></b>), modulated sevoflurane-mediated vasodilation. <b><it>Series 3 – 5 </it></b>examined the role of the Ca⁺⁺channel in sevoflurane induced vasodilation. Separate experiments examined whether verapamil, which blocks the sarcolemmal voltage-operated Ca⁺⁺channel (<b><it>Series 3</it></b>), SK&F 96365 an inhibitor of sarcolemmal voltage-independent Ca⁺⁺channels (<b><it>Series 4A+B</it></b>), or ryanodine an inhibitor of the sarcoplasmic reticulum Ca⁺⁺channel (<b><it>Series 5A+B</it></b>), modulated sevoflurane-mediated vasodilation.</p> <p>Results</p> <p>Sevoflurane produced dose dependent vasodilatation of chorionic plate arterial rings in all studies. Prior blockade of the K_Ca++and K_ATPchannels augmented the vasodilator effects of sevoflurane. Furthermore, exposure of rings to sevoflurane in advance of TEA occluded the effects of TEA. Taken together, these findings suggest that sevoflurane blocks K⁺channels. Blockade of the voltage-operated Ca⁺⁺channels inhibited the vasodilator effects of sevoflurane. In contrast, blockade of the voltage-independent and sarcoplasmic reticulum Ca⁺⁺channels did not alter sevoflurane vasodilation.</p> <p>Conclusion</p> <p>Sevoflurane appears to block chorionic arterial K_Ca++and K_ATPchannels. Sevoflurane also blocks voltage-operated calcium channels, and exerts a net vasodilatory effect in the <it>in vitro </it>foeto-placental circulation.</p