685 research outputs found
Appendicocecal Fistula – A Rare Complication of Appendicitis
Fistulisation of appendix to other organs or to the exterior through abdominal wall is a rare complication of appendicitis. We present one such rare case of appendicocecal fistula due to appendicitis in a patient initially managed conservatively for appendicular lum
Effect of an Inclined Magnetic Field on the Flow of Nanofluids in a Tapered Asymmetric Porous Channel with Heat Source/Sink and Chemical Reaction
This article deals with the effect of an inclined magnetic field with heat source/sink on the flow of nanofluids in a tapered asymmetric porous channel. Effect of chemical reaction has been taken into account. The blood is considered as an incompressible electrically conducting viscous fluid. The assumption of low Reynolds number and long wave length approximations has been adopted. Exact solutions for dimensionless axial velocity, concentration and temperature profile are obtained analytically. The obtained results are displayed and discussed in detail with the help of graphs for the variation of different emerging flow parameters
Literariness of Globalization: A Study of The White Tiger
Aravind Adiga`s The White Tiger was published in 2008 and it reflects India after globalization. The thematization of globalization in literature and in turn the influence of globalization on literature has been the concern of many critics in last few years. James Annesley’s Fictions of Globalization (2006) also treats globalization as a theme in a range of contemporary American fiction. But as it is evident that this project of analysing and discussing the relationship between literature and globalization is very vast and requires a lot of time and space, therefore the concern of this paper will be only The White Tiger. The process of globalization in India started with the introduction of New Economic process in 1991 after pursuing the import substitution for nearly forty years. Globalization as an economic activity has not remained detached with other cultural canons of the society. Not only in India, but the interchange of worldviews and ideas has resulted in a major transformation of the lifestyle living standard of people globally
The Effect of Corruption and Governance on Tax Revenues
Developing countries are typically unable to generate
sufficient amount of revenue from taxation because these countries face
a number of institutional problems in the process of revenue generation.
One of the main problems is corruption in tax administration. The two
important components of revenue generation are tax administration and
tax system reforms [Brondolo, et al. (2008)]. The main objective of
these is to increase the efficiency of tax administrations, specifically
by reducing corruption and tax evasion. The second main problem of low
revenue generation is political instabilities in developing countries.
One of the important characteristics of political instability is
unstable and governments and, hence, incoherent policy framework, which
hinder in the process of long-term reforms in the system. The quality of
governance as a whole is also relevant in this context. It is widely
agreed that the presence of tax evasion and corruption of public
officials is a social phenomenon that can significantly reduce tax
revenue and seriously hurt economic growth and development
Congenital Intranasal Glioma
Congenital midline swellings of nose are encountered rarely, and nasal gliomas constitute about 5% of such lesions. Various theories have been suggested to explain the pathogenesis. Imaging preferably by MRI is mandated to study the extent and to rule out intracranial extension. Treatment is complete excision, and the approach depends upon the extent of the lesion and availability of expertise. We present the management of one such case of congenital intranasal glioma without any intracranial extension that presented as a septal polyp
SECURING CENTRALIZED SDN CONTROL WITH DISTRIBUTED BLOCKCHAIN TECHNOLOGY
Software Defined Networks (SDN) advocates segregation of network control logic, forwarding functions and management applications into different planes to achieve network programmability, automated and dynamic flow control in next generation networks. It promotes deployment of novel and augmented network management functions to have flexible, robust, scalable and cost-effective network deployments. All these features introduce new research challenges and require secure communication protocols among the segregated network planes. This manuscript focuses on the security issue of southbound interface which operates between the SDN control and data plane. We have highlighted the security threats associated with an unprotected southbound interface and the issues related with the existing TLS based security solution. A lightweight blockchain based decentralized security solution is proposed for southbound interface to secure the resources of logically centralized SDN controllers and distributed forwarding devices from opponents. The proposed mechanism can operate in multi-domain SDN deployment and can be used with wide range of network controllers and data plane devices. In addition to it, the proposed security solution is analyzed in terms of security features, communication and reauthentication overhead
RELAXIN: A MAGICAL THERAPY FOR HEALTHY HEART
Relaxin (a peptide hormone) has emerged as a cardioprotective agent and plays a vital role in normal cardiac function. By activation a complex network of signaling cascade, relaxin is responsible for creating a healthy environment for heart functioning. Under pathological conditions, such as cardiomyopathy and heart failure, expression level of relaxin is increased dramatically to protect heart. By promoting angiogenesis, vasodilatation, improving ischemia/reperfusion injury and remodeling, relaxin has emerged as a magical agent to address cardiac abnormalities. Over the past 3 decades, various cardioprotection strategies are in use to deal with cardiac diseases, however till date no effective therapy is in clinical practice. Relaxin has emerged as a novel therapeutic agent to have beneficial action during various pathological conditions. In this review, we have discussed different cardioprotective roles of relaxin that marks it, as an effective agent to tackle heart related diseases.Â
THE WARBURG EFFECT: A POSSIBLE ROLE OF CAP INDEPENDENT TRANSLATION
Cancer is a complex multistep process involving tremendous changes at molecular and cellular properties of a cancerous cell. One of the main characteristics associated with the tumor cells include preferential use of glycolysis over oxidative phosphorylation to meet the high energy needs. This process is observed even in the presence of ample oxygen to fuel mitochondrial respiration and is considered to be the root cause of tumor growth and a potential hallmark of cancer. It has been found that tumor cells shows increased glycolytic capacity than normal cells and produce lactate rather than pyruvate in the process. During cancers, the expression levels of glycolytic enzymes are increased and different mechanisms like increased transcription or altered post-translational regulation has been proposed. Since hypoxia is a well known model in cancers and therefore role of capindependent translation cannot be ignored. Furthermore, elucidation of the underlying reasons behind the increased expression of glycolytic enzymes in cancer will help us to better understand and cure cancer. This review focuses on the possible role of cap independent translation in mediating increased expression of glycolytic enzymes in cancers. Key word: Cancer, Warburg Effect, glycolytic enzymes, Cap independent translation, hypoxi
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