'Un Bon Dessin Vaut Mieux Qu'un Long Discours' : the role and impact of cartoons in contemporary France

Cartoons have traditionally occupied an important place in French visual culture, and are now a permanent feature in even the most prestigious publications, including Le Monde, where they appear on the front page. Moreover, there is a long tradition of political cartooning which is firmly situated within the historical context of caricature and lampooning, which over the years has contributed to public debates on key issues such as politics, religion and social change. In this thesis, I focus on political cartoons and argue that the political cartoon is still significant as a cultural product and as a powerful journalistic medium at a time when the existence of the print media is threatened by new technological developments. In order to understand how cartoons remain a powerful mode of expression in the twenty-first century, I begin by examining the historical development of cartooning, tracing its origins in grotesque art, physiognomy and caricature. I then explore a number of events in early modern European history such as the Reformation and the French Revolution to show that the medium was used as a means of mass communication, to inform a largely illiterate public, incite protest and instigate rebellion through propaganda. I show how political graphics were used as effective political weapons against the ruling authorities, in the face of tight regulation such as censorship, and underline the French artists' commitment to defend their right of expression. As I demonstrate, this commitment continues to be pursued by contemporary French cartoonists such as Plantu who is dedicated to fighting for freedom of expression and promoting peace issues, under the banner of Le Monde and the United Nations. In analysing a corpus of Plantu's editorial creations, I underline theoretical perspectives for ‘reading' cartoons and illuminate the visual rhetoric used by cartoonists to communicate serious issues. I conclude with an assessment of the significant role that French cartoonists played during the 2006 Cartoons War to further highlight the impact of cartoons as a vehicle for political communication, and as a catalyst for debate in the twenty first century.EThOS - Electronic Theses Online ServiceGBUnited Kingdo

BDNF Val66Met and DRD2 Taq1A polymorphisms interact to influence PTSD symptom severity: A preliminary investigation in a South African population

BACKGROUND: We evaluated the role that selected variants in serotonin transporter (5-HTT), dopamine receptor 2 (DRD2) and brain-derived neurotrophic factor (BDNF) genes play in PTSD symptom severity in an at-risk population. We also investigated the interaction between the genetic variants to determine whether these variables and the interactions between the variables influenced the severity of PTSD symptoms. METHODS: PTSD symptoms were quantitatively assessed using the Davidson Trauma Scale (DTS) in 150 participants from an at-risk South African population. All participants were genotyped for the 5-HTTLPR, DRD2 Taq1A and BDNF Val66Met polymorphisms. Gene–gene interactions were investigated using various linear models. All analyses were adjusted for age, gender, major depressive disorder diagnosis, level of resilience, level of social support and alcohol dependence. RESULTS: A significant interaction effect between DRD2 Taq1A and BDNF Val66Met variants on DTS score was observed. On the background of the BDNF Val66Val genotype, DTS score increased significantly with the addition of a DRD2 Taq1A A1 allele. However, on the BDNF Met66 allele background, the addition of an A1 allele was found to reduce total DTS score. CONCLUSIONS: This study provides preliminary evidence for an epistatic interaction between BDNF Val66Met and DRD2 Taq1A polymorphisms on the severity of PTSD symptoms, where both too little and too much dopamine can result in increased PTSD symptom severity.Web of Scienc

Dust in Supernovae and Supernova Remnants I : Formation Scenarios

Supernovae are considered as prime sources of dust in space. Observations of local supernovae over the past couple of decades have detected the presence of dust in supernova ejecta. The reddening of the high redshift quasars also indicate the presence of large masses of dust in early galaxies. Considering the top heavy IMF in the early galaxies, supernovae are assumed to be the major contributor to these large amounts of dust. However, the composition and morphology of dust grains formed in a supernova ejecta is yet to be understood with clarity. Moreover, the dust masses inferred from observations in mid-infrared and submillimeter wavelength regimes differ by two orders of magnitude or more. Therefore, the mechanism responsible for the synthesis of molecules and dust in such environments plays a crucial role in studying the evolution of cosmic dust in galaxies. This review summarises our current knowledge of dust formation in supernova ejecta and tries to quantify the role of supernovae as dust producers in a galaxy.Peer reviewe

Effects and Moderators of Psychosocial Interventions on Quality of Life, and Emotional and Social Function in Patients With Cancer: An Individual Patient Data Meta-Analysis of 22 RCTS

Objective: This individual patient data (IPD) meta-analysis aimed to evaluate the effects of psychosocial interventions (PSI) on quality of life (QoL), emotional function (EF), and social function (SF) in patients with cancer, and to study moderator effects of demographic, clinical, personal, and intervention-related characteristics. Methods: Relevant studies were identified via literature searches in 4 databases. We pooled IPD from 22 (n = 4217) of 61 eligible randomized controlled trials. Linear mixed-effect model analyses were used to study intervention effects on the post-intervention values of QoL, EF, and SF (z-scores), adjusting for baseline values, age, and cancer type. We studied moderator effects by testing interactions with the intervention for demographic, clinical, personal, and intervention-related characteristics, and conducted subsequent stratified analyses for significant moderator variables.Results: PSI significantly improved QoL (β = 0.14,95%CI = 0.06;0.21), EF (β = 0.13,95%CI = 0.05;0.20), and SF (β = 0.10,95%CI = 0.03;0.18). Significant differences in effects of different types of PSI were found, with largest effects of psychotherapy. The effects of coping skills training were moderated by age, treatment type, and targeted interventions. Effects of psychotherapy on EF may be moderated by cancer type, but these analyses were based on 2 randomized controlled trials with small sample sizes of some cancer types. Conclusions: PSI significantly improved QoL, EF, and SF, with small overall effects. However, the effects differed by several demographic, clinical, personal, and intervention-related characteristics. Our study highlights the beneficial effects of coping skills training in patients treated with chemotherapy, the importance of targeted interventions, and the need of developing interventions tailored to the specific needs of elderly patients

Studying young recipients of alcohol marketing : Two research paradigms and their possible consolidation

Peer reviewe

MicroRNA Related Polymorphisms and Breast Cancer Risk

Peer reviewe