3,451 research outputs found
Quasirandomness in hypergraphs
An -vertex graph of edge density is considered to be quasirandom
if it shares several important properties with the random graph . A
well-known theorem of Chung, Graham and Wilson states that many such `typical'
properties are asymptotically equivalent and, thus, a graph possessing one
such property automatically satisfies the others.
In recent years, work in this area has focused on uncovering more quasirandom
graph properties and on extending the known results to other discrete
structures. In the context of hypergraphs, however, one may consider several
different notions of quasirandomness. A complete description of these notions
has been provided recently by Towsner, who proved several central equivalences
using an analytic framework. We give short and purely combinatorial proofs of
the main equivalences in Towsner's result.Comment: 19 page
Large-scale albuminuria screen for nephropathy models in chemically induced mouse mutants
Background/Aim: Phenotype-driven screening of a great pool of randomly mutant mice and subsequent selection of animals showing symptoms equivalent to human kidney diseases may result in the generation of novel suitable models for the study of the pathomechanisms and the identification of genes involved in kidney dysfunction. Methods: We carried out a large-scale analysis of ethylnitrosourea (ENU)-induced mouse mutants for albuminuria by using qualitative SDS-polyacrylamide gel electrophoresis. Results: The primary albuminuria screen preceded the comprehensive phenotypic mutation analysis in a part of the mice of the Munich ENU project to avoid loss of mutant animals as a consequence of prolonged suffering from severe nephropathy. The primary screen detected six confirmed phenotypic variants in 2,011 G1 animals screened for dominant mutations and no variant in 48 G3 pedigrees screened for recessive mutations. Further breeding experiments resulted in two lines showing a low phenotypic penetrance of albuminuria. The secondary albuminuria screen was carried out in mutant lines which were established in the Munich ENU project without preceding primary albuminuria analysis. Two lines showing increased plasma urea levels were chosen to clarify if severe kidney lesions are involved in the abnormal phenotype. This analysis revealed severe albuminuria in mice which are affected by a recessive mutation leading to increased plasma urea and cholesterol levels. Conclusion: Thus, the phenotypic selection of ENU-induced mutants according to the parameter proteinuria in principle demonstrates the feasibility to identify nephropathy phenotypes in ENU-mutagenized mice. Copyright (C) 2005 S. Karger AG, Basel
Minimum and maximum against k lies
A neat 1972 result of Pohl asserts that [3n/2]-2 comparisons are sufficient,
and also necessary in the worst case, for finding both the minimum and the
maximum of an n-element totally ordered set. The set is accessed via an oracle
for pairwise comparisons. More recently, the problem has been studied in the
context of the Renyi-Ulam liar games, where the oracle may give up to k false
answers. For large k, an upper bound due to Aigner shows that (k+O(\sqrt{k}))n
comparisons suffice. We improve on this by providing an algorithm with at most
(k+1+C)n+O(k^3) comparisons for some constant C. The known lower bounds are of
the form (k+1+c_k)n-D, for some constant D, where c_0=0.5, c_1=23/32=0.71875,
and c_k=\Omega(2^{-5k/4}) as k goes to infinity.Comment: 11 pages, 3 figure
Emerging Role of Nuclear Medicine in Oral and Maxillofacial Surgery
During the past several years, nuclear medicine has emerged as one of the most useful imaging studies in oral and maxillofacial surgery, not only in diagnosis and staging but also in the management plan and follow-up protocols of many cancer or inflammatory diseases. Nuclear medicine has in addition a special place in treating several benign and malignant diseases. The practicing maxillofacial surgeon’s knowledge of nuclear medicine capabilities and advantages and disadvantages of each modality is crucial in his or her daily work. The purpose of this chapter is to clarify the important role of nuclear medicine in diagnosis and treatment of oral and maxillofacial region pathologies as well as its indications and limitations in the daily practice of the oral and maxillofacial surgeon
Organized Current Patterns in Disordered Conductors
We present a general theory of current deviations in straight current
carrying wires with random imperfections, which quantitatively explains the
recent observations of organized patterns of magnetic field corrugations above
micron-scale evaporated wires. These patterns originate from the most efficient
electron scattering by Fourier components of the wire imperfections with
wavefronts along the direction. We show that long range
effects of surface or bulk corrugations are suppressed for narrow wires or
wires having an electrically anisotropic resistivity
Imaging geometry through dynamics: the observable representation
For many stochastic processes there is an underlying coordinate space, ,
with the process moving from point to point in or on variables (such as
spin configurations) defined with respect to . There is a matrix of
transition probabilities (whether between points in or between variables
defined on ) and we focus on its ``slow'' eigenvectors, those with
eigenvalues closest to that of the stationary eigenvector. These eigenvectors
are the ``observables,'' and they can be used to recover geometrical features
of
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