Pengaruh Promosi, Harga Dan Pelayanan Terhadap Keputusan Pembelian Toyota Dyna Dengan Jenis USAha Sebagai Variabel Moderasi (Studi Kasus Konsumen PT. New Ratna Motor, Semarang)

Goal of companies is become the market leader of their products. To achieve it, companies have to increase their sales volume. As Toyota brand holder in Central Java and DIY, PT. New Ratna Motor always tries to lead the market share in all car types, including two-tonnage vehicles (truck) class. Toyota Dyna becomes the favorite of Toyota in this class, which the competition in this class is tighter. Promotion, price, and service are some of important factors which can be related with consumer's purchase decision of Toyota Dyna and the other brands. This research is aimed to analyze is there any relation between promotion, price, and service to purchase decision of Toyota Dyna. It is continued by analysis of relationship between these three independent variables to purchase decision with business type as moderating variable. This is a quantitative research with 78 respondents as samples of Toyota Dyna users in Central Java and DIY. Questionnaires, interviews, and website are used in collecting data. Determination coefficient and Moderated Regression Analysis are used to analyze data. Result of this research is there are significant relations between promotion, price, and service to purchase decision of Toyota Dyna. Business type variable is not a moderating variable in these relationships. Advice for the company to increase sales in Toyota Dyna is develop better strategies in promotion, price, and service

GC-MS composition and antiproliferative activity of Inula graveolens (L.) Desf. essential oil

The composition of the essential oil isolated from the aerial parts of Inula graveolens (L.), (Asteraceae) was determined by GC and GC-MS using two extraction methods, namely hydrodistillation and Solid Phase Micro-Extraction (SPME). Oxygenated monoterpenes had the highest contribution to the hydro-distilled essential oil content (87.32 %) with bornyl acetate being the main component detected in this fraction (70.58 %). Both oxygenated monoterpenes, borneol (11.36%) and bornyl acetate (58.30%) remained as the major constituents while camphene was detected as the major hydrocarbon monoterpene (16.58%) in the SPME extracted oil. The antiproliferative activity of the crude oil and of some pure volatile compounds was evaluated using two breast cancer cell lines (MCF7 and T47D) and compared to reference drugs. The IC50 values of reference drugs; cisplatin and doxorubicin were 7.3 ± 1. 9 μM and 0.16 ± 0.0 μM for MCF7 cells, 21.3 ± 9.7 μM and 0.2 ± 0.0 μM for T47D cells, respectively. Caryophylline oxide was the main active compound of the volatile fraction with the IC values (μg/mL) for MCF7 cells and T47D cells, respectively (8.098 ± 0.71; 6.121 ± 0.818).This is the first time to investigate the essential oil composition of the aerial parts of I. graveolens using SPME. The findings of the present study demonstrated qualitative and quantitative variation in the composition of the essential oil between the two different extraction methods. The strong antiproliferative activity of caryophyllene oxide justifies the plants' use as an anticancer agent in the traditional medicine

Feasibility and systems definition study for Microwave Multi-Application Payload (MMAP)

Work completed on three Shuttle/Spacelab experiments is examined: the Adaptive Multibeam Phased Array Antenna (AMPA) Experiment, Electromagnetic Environment Experiment (EEE) and Millimeter Wave Communications Experiment (MWCE). Results included the definition of operating modes, sequence of operation, radii of operation about several ground stations, signal format, foot prints of typical orbits and preliminary definition of ground and user terminals. Conceptual hardware designs, Spacelab interfaces, data handling methods, experiment testing and verification studies were included. The MWCE-MOD I was defined conceptually for a steerable high gain antenna

Double negative alpha beta T cells in pediatric hemophagocytic syndromes

Introduction: Autoimmune lymphoproliferative syndrome (ALPS) and hemophagocytic lymphohistiocytosis (HLH) share clinical and laboratory features including lymphadenopathy, splenomegaly, and pancytopenia. We sought to measure αβ double negative T cells (αβ DNT) in a group of patients with established diagnosis of HLH in relation to disease activity and severity.Methods: We conducted a follow-up, controlled study that comprised 25 patients with HLH and 25 healthy matched controls. Patients were subjected to clinical evaluation and flowcytometric measurement of αβ DNT Cells at presentation and 9 weeks after start of HLH induction treatment.Results: In 17 (68%) patients, infection was the trigger of HLH while the cause was malignancy in three (12%), and rheumatological disorders in two patients (8%). At enrollment, 15 patients (60%) had αβ DNT cells levels [median (IQR): 1.71 (1.25-2.12)] that were significantly higher than the control values [median (IQR): 0.7 (0.4-0.8)] (p<0.001). The αβ DNT counts of patients were also higher at enrollment as compared to values at the end of week 9 [median (IQR): 0.76 (0.45-1.17)]; p=0.018. Survivors (n=8) and non-survivors (n=17) had comparable levels of αβ DNT cells at enrollment (p=0.861). αβ DNT cell count correlated positively with ALT (p=0.019) and negatively with CD4/CD8 ratios (p=0.023).Conclusion: Elevated αβ DNT cell counts might be related to the HLH process and this implies that mild elevation can exist in HLH and are not specific to ALPS. Wider scale studies with longer periods of follow up are needed to validate the results and properly outline the correlation between both medical conditions.Keywords: Hemophagocytic lymphohistiocytosis, Double negative T cells, mortality, ALP

The development of an assesment framework for vocational education taining programmes in the noss based training system (NBTS) and the national dual training system (NDTS)

There are two skills training systems in Malaysia, namely NOSS Based Training System (NBTS) and National Dual Training System (NDTS). Although both systems have different training and assessment approaches, both systems produce national skilled workers with the same certification known as the Malaysian Skills Certificate (MSC). In order to manage and monitor both systems concurrently, a standardised assessment system need to be in place to ensure that the training given is efficient and effective in producing competent and employable k-workers. Therefore, the objective of the study was to develop a comprehensive assessment framework for both skill training systems as guidance to those personnel who are involved in conducting skill training. This study used mixed method mode approach and utilised structured interview, questionnaire and mapping table from document analysis as data collection instruments to gather information on the dimension of assessment. The sample of the study constituted 269 personnel from accredited centers and agencies which conduct NDTS or/and NBTS approaches. Several statistical techniques were used to analyse the data: descriptive statistics (frequency, mean, standard deviation and percentage) was used to explain the respondents profile; Exploratory Factor Analysis (EFA) was used to determine the dimension of the assessment framework and this was validated by Parallel Analysis (PA) and the Minimum Average Partial (MAP) test; descriptive from the EFA was used to develop a model of assessment framework and this model was validated by the use of Structural Equation Modeling (SEM). There were three outcomes from the study. Firstly, both systems NBTS and NDTS were considered similar although some of the sub dimensions were not. From this finding, a common assessment framework was developed for NBTS and NDTS approaches with special treatment for the differences. Secondly, six dimensions of assessment framework were identified, and finally an assessment framework for both systems was developed. The developed assessment framework will ensure whether the quality of assessment in the accredited center achieves the international skill standard