Pathway aberrations of murine melanoma cells observed in Paired-End diTag transcriptomes-2

<p><b>Copyright information:</b></p><p>Taken from "Pathway aberrations of murine melanoma cells observed in Paired-End diTag transcriptomes"</p><p>http://www.biomedcentral.com/1471-2407/7/109</p><p>BMC Cancer 2007;7():109-109.</p><p>Published online 26 Jun 2007</p><p>PMCID:PMC1929113.</p><p></p>ere added to the upper left corner of the gene box (green icon, with 4 numbers to represent a particular KEGG gene ID). Each square is associated with a library and highlighted with red, yellow, or blue color to indicate that gene isoforms are all matched, partially matched, or completely unmatched, respectively, by PETs of the library. By placing the cursor on a particular entity (mouse on), one can view the description of all gene isoforms in the gene box (II), or PET counts, in cpm (counts per million), of a corresponding gene isoform for each library (III & IV). In response to a clicking on a solid square, detailed mapping information is displayed (V). Hyperlinks in II lead to all KEGG pathway images that contain the selected gene isoform

Pathway aberrations of murine melanoma cells observed in Paired-End diTag transcriptomes-0

<p><b>Copyright information:</b></p><p>Taken from "Pathway aberrations of murine melanoma cells observed in Paired-End diTag transcriptomes"</p><p>http://www.biomedcentral.com/1471-2407/7/109</p><p>BMC Cancer 2007;7():109-109.</p><p>Published online 26 Jun 2007</p><p>PMCID:PMC1929113.</p><p></p> each active 'gene box' (green), two solid squares are added to the upper left corner to reflect the associated information for the Melan-a2 melanocyte library (SMN001_36623nr2, left) and the B16F1 melanoma library (SMT001_32267nr2, right). PET counts associated with each gene isoform can be accessed by clicking on the library squares. Gene isoform-associated PET counts of the melanocyte library and the melanoma library are displayed side by side and compared to demonstrate the transcriptional downregulation of these gene isoforms in melanoma cells. PET counts are normalized to cpm (counts per million)

Pathway aberrations of murine melanoma cells observed in Paired-End diTag transcriptomes-1

<p><b>Copyright information:</b></p><p>Taken from "Pathway aberrations of murine melanoma cells observed in Paired-End diTag transcriptomes"</p><p>http://www.biomedcentral.com/1471-2407/7/109</p><p>BMC Cancer 2007;7():109-109.</p><p>Published online 26 Jun 2007</p><p>PMCID:PMC1929113.</p><p></p>r associated PET counts. Two solid squares are added to each active 'gene box' (green) for accessing PET data related to gene isoforms: the left square links to the Melan-a2 melanocyte library (SMN001_36623nr2), while the right square links to the B16F1 melanoma library (SMT001_32267nr2). The degree of PET-to-gene isoform matching is indicated by different colors: blue, no match at all; yellow, partially matched; and red, all isoforms matched (by PETs). Boxes in the lower portion show PET counts for the gene isoforms of each pair of cyclin (top) and CDK (bottom). PET counts have been normalized to cpm (counts per million)