Thermal melting of density waves on the square lattice

We present the theory of the effect of thermal fluctuations on commensurate "p x p" density wave ordering on the square lattice (p >= 3, integer). For the case in which this order is lost by a second order transition, we argue that the adjacent state is generically an incommensurate striped state, with commensurate p-periodic long range order along one direction, and incommensurate quasi-long-range order along the orthogonal direction. We also present the routes by which the fully disordered high temperature state can be reached. For p=4, and at special commensurate densities, the "4 x 4" commensurate state can melt directly into the disordered state via a self-dual critical point with non-universal exponents.Comment: 12 pages, 5 figure

Signature Characters for A_2 and B_2

The signatures of the inner product matrices on a Lie algebra's highest weight representation are encoded in the representation's signature character. We show that the signature characters of a finite-dimensional Lie algebra's highest weight representations obey simple difference equations that have a unique solution once appropriate boundary conditions are imposed. We use these results to derive the signature characters of all $A_2$ and $B_2$ highest weight representations. Our results extend, and explain, signature patterns analogous to those observed by Friedan, Qiu and Shenker in the Virasoro algebra's representation theory.Comment: 22 p

A re-interpretation of the Triangulum-Andromeda stellar clouds: a population of halo stars kicked out of the Galactic disk

The Triangulum-Andromeda stellar clouds (TriAnd1 and TriAnd2) are a pair of concentric ring- or shell-like over-densities at large $R$ ($\approx$ 30 kpc) and $Z$ ($\approx$ -10 kpc) in the Galactic halo that are thought to have been formed from the accretion and disruption of a satellite galaxy. This paper critically re-examines this formation scenario by comparing the number ratio of RR Lyrae to M giant stars associated with the TriAnd clouds with other structures in the Galaxy. The current data suggest a stellar population for these over-densities ($f_{\rm RR:MG} < 0.38$ at 95% confidence) quite unlike any of the known satellites of the Milky Way ($f_{\rm RR:MG} \approx 0.5$ for the very largest and $f_{\rm RR:MG} >>1$ for the smaller satellites) and more like the population of stars born in the much deeper potential well inhabited by the Galactic disk ($f_{\rm RR:MG} < 0.01$). N-body simulations of a Milky-Way-like galaxy perturbed by the impact of a dwarf galaxy demonstrate that, in the right circumstances, concentric rings propagating outwards from that Galactic disk can plausibly produce similar over-densities. These results provide dramatic support for the recent proposal by Xu et al. (2015) that, rather than stars accreted from other galaxies, the TriAnd clouds could represent stars kicked-out from our own disk. If so, these would be the first populations of disk stars to be found in the Galactic halo and a clear signature of the importance of this second formation mechanism for stellar halos more generally. Moreover, their existence at the very extremities of the disk places strong constraints on the nature of the interaction that formed them.Comment: 27 pages, 8 figures; published in MNRA

Environmental protection of titanium alloys in centrifugal compressors at 500°C in saline atmosphere

The use of the titanium alloy Ti-6246 (Ti–6Al–2Sn–4Zr–6Mo, wt-%) for gas turbine compressors allows an increase in working temperature and stress level. Under severe service conditions, the material experiences combined high temperature and high mechanical stress and, in saline atmospheres, stress corrosion cracking (SCC) can occur, leading to catastrophic mechanical failure. The present study was performed to evaluate the potential of several surface treatments to protect Ti-6246 alloy, after salt deposit, from hot salt SCC at temperatures ?500°C and 500 MPa static mechanical stress conditions. Shot peening, thermal oxidation and metal–ceramic coatings were investigated. Experimental results confirm the existence of brittle stress corrosion phenomena marked by a low residual elongation of test samples and the presence of oxides on the fracture surfaces. Both shot peening and metal–ceramic coatings increase the hot salt SCC resistance of the alloy. Times to rupture were improved by a factor of 3 for shot peening and by a factor of 10 for metal–ceramic coatings. Inversely, the time to rupture of preoxidised alloys has been halved compared with uncoated alloys. As well as these interesting quantitative results, structural studies of metal–ceramic coatings showed that they are mechanically and chemically compatible with the titanium alloy substructure and should work under severe thermomechanical stresses and aggressive atmospheres

Kadanoff-Baym approach to time-dependent quantum transport in AC and DC fields

We have developed a method based on the embedded Kadanoff-Baym equations to study the time evolution of open and inhomogeneous systems. The equation of motion for the Green's function on the Keldysh contour is solved using different conserving many-body approximations for the self-energy. Our formulation incorporates basic conservation laws, such as particle conservation, and includes both initial correlations and initial embedding effects, without restrictions on the time-dependence of the external driving field. We present results for the time-dependent density, current and dipole moment for a correlated tight binding chain connected to one-dimensional non-interacting leads exposed to DC and AC biases of various forms. We find that the self-consistent 2B and GW approximations are in extremely good agreement with each other at all times, for the long-range interactions that we consider. In the DC case we show that the oscillations in the transients can be understood from interchain and lead-chain transitions in the system and find that the dominant frequency corresponds to the HOMO-LUMO transition of the central wire. For AC biases with odd inversion symmetry odd harmonics to high harmonic order in the driving frequency are observed in the dipole moment, whereas for asymmetric applied bias also even harmonics have considerable intensity. In both cases we find that the HOMO-LUMO transition strongly mixes with the harmonics leading to harmonic peaks with enhanced intensity at the HOMO-LUMO transition energy.Comment: 16 pages, 9 figures. Submitted at "Progress in Nonequilibrium Green's Functions IV" conferenc

Vaccines against malaria

There is no licenced vaccine against any human parasitic disease and Plasmodium falciparum malaria, a major cause of infectious mortality, presents a great challenge to vaccine developers. This has led to the assessment of a wide variety of approaches to malaria vaccine design and development, assisted by the availability of a safe challenge model for small-scale efficacy testing of vaccine candidates. Malaria vaccine development has been at the forefront of assessing many new vaccine technologies including novel adjuvants, vectored prime-boost regimes and the concept of community vaccination to block malaria transmission. Most current vaccine candidates target a single stage of the parasite's life cycle and vaccines against the early pre-erythrocytic stages have shown most success. A protein in adjuvant vaccine, working through antibodies against sporozoites, and viral vector vaccines targeting the intracellular liver-stage parasite with cellular immunity show partial efficacy in humans, and the anti-sporozoite vaccine is currently in phase III trials. However, a more effective malaria vaccine suitable for widespread cost-effective deployment is likely to require a multi-component vaccine targeting more than one life cycle stage. The most attractive near-term approach to develop such a product is to combine existing partially effective pre-erythrocytic vaccine candidates

Systematic review and meta-analysis of secondary prophylaxis for prevention of HIV-related toxoplasmic encephalitis relapse using trimethoprim-sulfamethoxazole

A recent systematic literature and meta-analysis reported relative efficacy of trimethoprim-sulfamethoxazole (TMP-SMX) for the treatment of toxoplasmic encephalitis (TE) in HIV-infected adults. Here, we estimated relapse rates during secondary prophylaxis with TMP-SMX, and further explored differences in relapse rates prior to introduction of highly active antiretroviral therapy (HAART) and the widespread adoption of HAART. A systematic search of PubMed, Embase, and Cochrane Central Register of Controlled Trials yielded 707 studies whereby 663 were excluded after abstract screening, and 38 were excluded after full review leaving 6 studies for extraction. We performed double data extraction with a third-party adjudicator. Study designs varied with only one randomized study, four prospective cohorts and one retrospective cohort. Relapse rates were transformed using the Freeman-Tukey method and pooled using both fixed-effect and random-effects meta-analysis models. The TMP-SMX relapse rate was 16.4% (95% CI = 6.2% to 30.3%) based on random-effects models. When the disaggregated pre-HAART studies (n = 4) were included, the relapse rate was 14.9% (random effects; 95% CI = 3.7% to 31.9%). Analysis of two post-HAART studies indicated a relapse rate of 19.2% (random effects; 95% CI = 2.8% to 45.6%). Comparing the relapse rates between pre- and post-HAART studies were contrary to what might be expected based on known benefits of HAART therapy in this population. Nevertheless, cautious interpretation is necessary considering the heterogeneity of the included studies and a limited number of subjects receiving TMP-SMX reported in the post-HAART era.Revisión por pare

The adjoint problem in the presence of a deformed surface: the example of the Rosensweig instability on magnetic fluids

The Rosensweig instability is the phenomenon that above a certain threshold of a vertical magnetic field peaks appear on the free surface of a horizontal layer of magnetic fluid. In contrast to almost all classical hydrodynamical systems, the nonlinearities of the Rosensweig instability are entirely triggered by the properties of a deformed and a priori unknown surface. The resulting problems in defining an adjoint operator for such nonlinearities are illustrated. The implications concerning amplitude equations for pattern forming systems with a deformed surface are discussed.Comment: 11 pages, 1 figur

Measurements of the Casimir-Lifshitz force in fluids: the effect of electrostatic forces and Debye screening

In this work, we present detailed measurements of the Casimir-Lifshitz force between two gold surfaces (a sphere and a plate) immersed in ethanol and study the effect of residual electrostatic forces, which are dominated by static fields within the apparatus and can be reduced with proper shielding. Electrostatic forces are further reduced by Debye screening through the addition of salt ions to the liquid. Additionally, the salt leads to a reduction of the Casimir-Lifshitz force by screening the zero-frequency contribution to the force; however, the effect is small between gold surfaces at the measured separations and within experimental error. An improved calibration procedure is described and compared to previous methods. Finally, the experimental results are compared to Lifshitz's theory and found to be consistent for the materials used in the experiment.Comment: 11 figures. PRA in pres