Endoscopic Excision of Cribriform Plate Schwannoma: A Case Report

Although 25-45% of all schwannomas occur in the head and neck, nasal and paranasal sinus presentations are rare in the literature. Here we report the case of a 67-year-old woman with a nasal schwannoma. Computerized tomography (CT) showed the mass completely occluding the nasal passage with evidence of a secondary maxillary sinusitis. A preoperative biopsy suggested the presence of a benign schwannoma. She underwent a complete endoscopic sinus surgery to remove the mass arising from the cribriform plate. Six years after surgery, the patient remains asymptomatic and without endoscopic evidence of recurrence. This case demonstrates that it is possible to achieve a complete excision of a nasal schwannoma endoscopically, which is similar to results observed for other benign nasal tumors

Kribriform plate schwannomasının endoskopik yaklaşımı ile eksizyonu: Bir olgu sunumu

Schwannomalar baş ve boyunda %25 ile 45 arasında görülmesine rağmen burun ve paranazal sinüslerde çok daha ender rastlanırlar. Biz bu yazıda 67 yaşındaki nazal schwannomalı bir hastayı sunduk. Bilgisayarlı tomogra- fide kitlenin tüm nazal kaviteyi bloke ederek sekonder maksiller sinüzite neden olduğu görüldü. Preoperatif biyopside benign schwannoma tanısı kondu. Kribriform plateden kaynaklanan kitle endoskopik sinus cerrahisi ile eksize edildi. Cerrahiden 6 yıl sonrası hasta asempto- matik idi ve endoskopik muayenede rekürrens görülme- di. Bu vaka bize nazal schwannomaların da, diğer benign nazal tümörler gibi tamamının endoskopik olarak eksiz- yonunun mümkün olduğunu göstermiştir.Although 25-45% of all schwannomas occur in the head and neck, nasal and paranasal sinus presentations are rare in the literature. Here we report the case of a 67-year-old woman with a nasal schwannoma. Comput- erized tomography (CT) showed the mass completely occluding the nasal passage with evidence of a second- ary maxillary sinusitis. A preoperative biopsy suggested the presence of a benign schwannoma. She underwent a complete endoscopic sinus surgery to remove the mass arising from the cribriform plate. Six years after surgery, the patient remains asymptomatic and without endoscopic evidence of recurrence. Tis case demonstrates that it is possible to achieve a complete excision of a nasal schwannoma endoscopically, which is similar to results observed for other benign nasal tumors

Verruciform Xanthoma of a Lower Lip Lesion: A New Case and Review of the Literature

A non-smoking man in his seventh decade presented with a lesion he had had for about 5 years on the right external surface of the lip 1 mm from the vermilion border. On physical examination, a yellowish-coloured, non-tender, verrucous mass of 0.5 × 0.7 cm was observed. A histopathological examination of the first 3-mm punch biopsy was non-diagnostic. The histopathological evaluation of a second, 5-mm-deep punch biopsy made by a pathology expert in oral lesions revealed a diagnosis of verruciform xanthoma. The key to the diagnosis of verruciform xanthoma is to recognize xanthoma cells. However, these cells may be insufficient in number in small and superficial biopsy material and overlooked by a pathologist especially when lacking knowledge of this uncommon lesion. Verruciform xanthoma of the lower lip at the vermilion border is an extremely rare entity described in 5 cases worldwide to date. We aimed to bring verruciform xanthoma to readers’ attention for a differential diagnosis of lower lip diseases and to prevent overdiagnosis and overtreatment of this lesion unfamiliar to otorhinolaryngologists

Caloric restriction increases internal iliac artery and penil nitric oxide synthase expression in rat: Comparison of aged and adult rats

Because of the positive corelation between healthy cardiovascular system and sexual life we aimed to evaluate the effect of caloric restriction (CR) on endothelial and neuronal nitric oxide synthase (eNOS, nNOS) expression in cavernousal tissues and eNOS expression in the internal iliac artery in young and aged rats. Young (3 mo, n = 7) and aged (24 mo, n = 7) male Sprague-Dawley rats were subjected to 40% CR and were allowed free access to water for 3 months. Control rats (n = 14) fed ad libitum had free access to food and water at all times. On day 90, rats were sacrified and internal iliac arteries and penis were removed and parafinized, eNOS and nNOS expression evaluated with immunohistochemistry. Results were evaluated semiquantitatively. eNOS and nNOS expression in cavernousal tis- sue in CR rats were more strong than in control group in both young and old rats. eNOS expression was also higher in the internal iliac arteries of CR rats than in control in young and old rats. As a result of our study we can say that there is a positive link between CR and neurotransmitter of erection in cavernousal tissues and internal iliac arteries. CR has beneficial effect to prevent sexual dysfunction in young and old animals and possible humans

Transitional cell carcinoma with glandular differentiation metastatic to the inguinal lymph node from the urinary bladder

Metastasis to the inguinal lymph nodes is a rare event in bladder cancer. In general, tumors at the metastatic foci are histologically similar to the primary. We report a metastatic adenocarcinoma in the inguinal lymph node from a primary, pure transitional cell carcinoma after radical cystectomy

Verruciform Xanthoma of a Lower Lip Lesion: A New Case and Review of the Literature

A non-smoking man in his seventh decade presented with a lesion he had had for about 5 years on the right external surface of the lip 1 mm from the vermilion border. On physical examination, a yellowish-coloured, non-tender, verrucous mass of 0.5 × 0.7 cm was observed. A histopathological examination of the first 3-mm punch biopsy was non-diagnostic. The histopathological evaluation of a second, 5-mm-deep punch biopsy made by a pathology expert in oral lesions revealed a diagnosis of verruciform xanthoma. The key to the diagnosis of verruciform xanthoma is to recognize xanthoma cells. However, these cells may be insufficient in number in small and superficial biopsy material and overlooked by a pathologist especially when lacking knowledge of this uncommon lesion. Verruciform xanthoma of the lower lip at the vermilion border is an extremely rare entity described in 5 cases worldwide to date. We aimed to bring verruciform xanthoma to readers’ attention for a differential diagnosis of lower lip diseases and to prevent overdiagnosis and overtreatment of this lesion unfamiliar to otorhinolaryngologists

Henoch-Schönlein purpura without systemic involvement beginning with acute scrotum and mimicking torsion of testis

Henoch-Schönlein purpura (HSP) is the most common systemic vasculitis in children. Typical presentations of HSP are palpable purpura of the small vessels in the hips and lower limbs, abdominal pain, arthritis, and hematuria. Scrotal involvement manifested by the presence of scrotal pain and swelling during the course of the disease is rarely seen. HSP without systemic involvement with acute scrotum mimicking testicular torsion is even rare in the medical literature. In most cases, patients with this disease achieve complete recovery. Herein, we report an interesting HSP case with skin symptoms but without systemic involvement and then progression to acute scrotum resembling torsion of testis