Periapical lesions of the jaws: A review of 104 cases in Ibadan

Background: Periapical lesions (PLs) occur as a result of pulpal inflammation and may rarely be seen in the absence of pulpal diseases. They are the most common pathological lesions affecting the alveolar bone.Objective: This study aims to describe the clinicopathological features of PLs of the jaws with emphasis on the two most common types.Methods: Histopathology records of PLs diagnosed from January 1990 toDecember 2012 at the Department of Oral Pathology, University CollegeHospital Ibadan, were examined and categorized into periapical cysts (PCs); periapical granuloma (PGs) and others. Clinical data and  histopathological features of these PLs were reviewed and analyzed.Results: One hundred and four lesions met the criteria for this study andconsisted of PGs with 71 (68.3%) cases and PCs with 31 (29.8%) cases and one case each of apical scar and pleomorphic adenoma. Age range of cases was 9 to 80 years (mean=35.6 ± 15.8years) with a peak at age group of 20-29 years. Females were more frequently affected with 51.9% of cases. PLs were most frequently diagnosed in the anterior maxillary region with 58 (56.9%) cases, while the most frequently involved tooth was the left maxillary central incisor with 23 (22.1%) cases.Conclusion: Findings in this study are consistent with those of previous studies. It is important for all periapical pathological specimens to be submitted for histological examination to establish an accurate diagnosis and aid in the identification of sinister lesions that may present in the Periradicular region of teeth.Keywords: Periapical, Cyst, Granuloma, Histopathology, Ja

Serum Uric Acid Levels in Oral Cancer Patients Seen at Tertiary Institution in Nigeria

Introduction: Toxicity by oxygen radicals has been considered as an important cause of cancer. It is proposed that the antioxidant properties of uric acid may act to prevent formation of oxygen radicals and thereby protect against carcinogenesis. This study aims to assess the role of uricacid in the aetiology of oral cancer.Materials and Methods: Thirty one oral cancer patients and thirty normal patients had serum uric acid measured using spectophotometer. The data obtained was analyzed using the Statistical Package for the Social Sciences, version 19.0 (SPSS19). Statistical significance was determined at P < 0.05. Results: The mean serum uric acid level in oral cancer patientswas 5.18 mg/dl (SD±1.96) while the mean was 7.09 mg/dl (SD±1.84) for the control group and this difference was statistically significant (p=0.000, t= -3.914, C.I. = - 2.885 to - 0.933). The risk of oral cancer was 3.98 times more in patients who had low serum uric acid.Conclusion: This study showed that serum uric acid was lower in oral cancer patients compared with healthy volunteers and low serum uric acid was associated with increased risk of oral cancer development. However, further prospective cohort studies are suggested to better understand the role of serum uric acid in aetiology of oral cancer

The role of forensic dentist following mass disaster

This review article focuses on mass disaster situations that may arise from natural or manmade circumstances and the significant role of forensic dental personnel in human identification following such occurrences. The various forensic dental modalities of identification that include matching techniques, postmortem profiling, genetic fingerprinting, dental fossil assessment and dental biometrics with digital subtraction were considered. The varying extent of use of forensic dental techniques and the resulting positive impact on human identification were considered. The importance of preparation by way of special training for forensic dental personnel, mock disaster rehearsal, and use of modern day technology was stressed. The need for international standardization of identification through the use of Interpol Disaster Victim Identification (DVI) for ms was further emphasized. Recommendations for improved human identification in Nigerian situation include reform of the National Emergency Management Association (NEMA), incorporation of dental care in primary health care to facilitate proper ante mortem database of the populace and commencement of identification at site of disaster

Serum antioxidant vitamins and the risk of oral cancer in patients seen at a tertiary institution in Nigeria

Objectives: Tobacco and alcohol are major risk factors of oral cancer, but nutritional deficiency may also contribute to development of oral cancer. This study compared serum antioxidant vitamin levels in oral cancer patients and controls in order to validate the role of vitamin deficiencies in the etiology of oral cancer. Materials and Methods: Serum vitamin A, C, and E levels of 33 oral cancer patients and 30 controls at University College Hospital, Ibadan, Nigeria, were determined using standard methods. The data obtained were analyzed using the Student t‑test, odds ratio, and logistic regression. Results: Mean vitamin A, C, and E levels were significantly lower in oral cancer patients (P=0.022, P=0.000, and P=0.013 respectively). Risk of oral cancer was 10.89, 11.35, and 5.6 times more in patients with low serum vitamins A, C, and E, respectively. However, on logistic regression analysis, only low serum vitamin E independently predicted occurrence of oral cancer. Conclusions: The lower serum vitamin A, C, and E levels in oral cancer patients could be either a cause or an effect of the oral cancer. Further studies using a larger sample size and cohort studies with long‑term follow‑up of subjects are desirable.Keywords: Antioxidant vitamins, Nigeria, oral cancer riskNigerian Journal of Clinical Practice •Jan-Mar 2012 • Vol 15 • Issue

An update on halitosis.

No Abstrac

Dental anxiety: Investigative and management techniques often employed in a cross section of Nigerian Specialist Dental Clinics

Background: Information on the pattern of dental anxiety management in Nigeria is currently not available. Aim: The study was designed to determine the awareness and frequency of application of dental anxiety assessment questionnaires as well as the current pattern in the management of dental anxiety in Nigeria. Methods: The cross-sectional study was conducted using structured questionnaires distributed among dental residents and house officers in Nigerian dental schools. Information requested included demographic variables, frequency of presentation of dental anxiety, awareness and frequency of application of dental anxiety questionnaires. The respondents were also asked to rate the frequency of application of the outlined dental anxiety management techniques on a 5-point Likert scale. The median score and the range for each technique was determined and compared between  the  male and  female  respondents. Results: A total of 96 questionaires  were  sent out to dental surgeons of all grades. Response was obtained from 86 giving a response rate of 90%. Only 23 (26.7%) respondents were aware of dental anxiety questionnaires while only 13 (15.1%) have seen the instrument applied. The percentage of patients with dental anxiety was estimated by the respondents to b

Dental anxiety among patients visiting a University Dental Centre

Objective: Fearful individuals often avoid care despite extensive dental needs and anxious patients feel more pain and of longer duration than less anxious patients. This study was designed to determine the prevalence and factors associated with dental anxiety among patients visiting a University Dental Centre in Nigeria.Method: This cross-sectional study was conducted using an anonymous structured questionnaire randomly administered to patients attending the University College Hospital Dental Centre, Ibadan. The questionnaire requested for socio-demographic data, dental visit behaviour, history of traumatic dental treatment and level of apprehension when anticipating a visit to the dentist and physician. The level of dental anxiety was determined using the Modified Dental Anxiety Scale (MDAS). An MDAS score of 19 and above indicated high dental anxiety. Upon examination, DMFT of each patient was determined.Result: A total of 471 respondents of which 262 (55.6%) were females participated in the study. Only 7.43% of the participants had MDAS score ≥19. About 10% of the females had high dental anxiety compared with 4.94% recorded for the males (p=0.01). Dental anxiety was more common among the younger age group, irregular oral health care seekers and among those with history of traumatic dental treatment. The respondents were more relaxed when anticipating a visit to a physician. Only gender could be used to predict high dental anxiety. Female gender significantly displayed high dental anxiety (odd ratio=3.05 and p=0.04) . The mean DMFT score for the patients was 2.48±3.30.Conclusion: The prevalence of dental anxiety among the respondents in this study was 7.43% and only gender could be used to predict dental anxiety.Keywords: Dental anxiety, dental fear, MDA Scale, prevalenc

Malignant salivary gland tumours of the head and neck region: A single institutions review

Introduction: malignant salivary gland tumours (MSGTs) comprise about 3% of all head and neck cancers; they demonstrate an unpredictable clinical course. The purpose of this study is to review MSGTs seen at a tertiary Health centre, and compare findings with those of previous studies. Methods: the records of the Department of Oral Pathology and the Department of Pathology, University College Hospital Ibadan were reviewed over a 19 year period and lesions diagnosed as MSGTs according to 2005 WHO histological classification were analysed for age, gender and site using SPSS for Windows (version 20.0; SPSS Inc. Chicago, IL). Results: MSGTs were more common in males (55.2%) than females (44.8%). The mean age of was 47.9 (±17.0) years and peak age was the fifth decade. The parotid gland was the commonest site with 62 (28.1%) cases. The palate was the commonest intraoral site with 61(27.6%). The nose with 19 (8.6%) was the commonest minor extra-oral site. Conclusion: the findings were essentially similar to reports from Europe and America. ACC was the most common MSGT in this series. A high proportion of salivary gland tumours in sublingual gland were malignant. The reason(s) for high proportion of MSGTs in sublingual glands requires further investigation