Distribution of auxological data in SMA patients (BMI = body mass index, WC = waist circumference, HC = hip circumference, WHR waist-to-hip ratio, SDS = standard deviation score).

<p>Vertical lines in bold (- 2 SD, + 2 SD) indicate the reference range. Boxes indicate the interquartile range (IQR), whiskers indicate 1.5xIQR, black dots are outliers. Asterisks indicate a significant deviation of the median from zero (p <0.01) with a shift towards higher values for WHR and leptin, as well as a shift to lower values for weight, height, BMI und HC.</p

The relation between motor function and leptin SDS in terms of SMA type, showing that the lower the overall motor function, the higher was the risk for elevated leptin levels.

<p>Vertical lines in bold at -2 SD and +2 SD indicate the reference range for leptin SDS. <b>As a consequence, lower motor function is linked to high leptin-SDS independent of SMA type</b>.</p

Association between leptin SDS and motor function.

<p>Association between leptin SDS and motor function.</p

Association between leptin SDS and SMA type.

<p>Association between leptin SDS and SMA type.</p