4,107 research outputs found
Provenance and environmental risk of windblown materials from mine tailing ponds, Murcia, Spain
Atmospheric particulates play a vital role in the transport of potentially toxic metals, being an important exposure pathways of people to toxic elements, which is faster and can occur in a much larger scale than water, soil and biota transport. Windblown materials in abandoned tailing ponds have not been well examined. The objectives of this investigation were: to study the major physical and geochemical properties of the materials eroded by wind inside the tailing ponds, and to understand the relative contribution of different sources to its heavy metals concentration. Study area is located in Cartagena-La Union mining district (SE Spain), where metallic mining of Fe, Pb and Zn has been developed for more than 2500 years. Wind-eroded particulates were monthly collected at 3 different heights (20, 50, and 80 cm) from the ground for a period of a full year using 4 dust collectors. Four tailing samples and 4 surface soil samples from the surrounding hills were also taken. Dust, soil, and tailing samples were examined for pH, particle size distribution, electrical conductivity, calcium carbonate content, Pb, Cu, Zn, Cd, Mn, Co, Ni, Ti and Zr concentrations. The results indicated that very coarse textured, slightly saline, and almost neutral wind-eroded deposits were generated with a very high temporal variability throughout the year. They also showed that the concentration of Cd, Mn, Pb and Zn, in the dust samples is extraordinarily high (18, 1254, 1831, and 5747 mg kg-1 respectively), whereas Co, Ni, and Cu had concentrations into the range of background concentrations found in the Earthâs crust (3.8, 12, and 60 mg kg-1 respectively). Besides, the concentration of both categories of heavy metals in the dust samples was higher than that in tailing and less than that of the soils. The barren surfaces of tailing ponds and also the surface soils of the surrounding area seem to be the major contributors to the dust collected. Therefore, abandoned mines as well as their tailing ponds should be rehabilitated by proper technologies and then well stabilized and /or covered by appropriate plant vegetation to control the transfer, particularly by air, of environmentally hazardous materials to other areas.Este artĂculo fue financiado por las universidades Isfahan University of Technology y Shahrood University of Technology (IrĂĄn) a travĂ©s de las estancias de los profesores Khademi y Abbaspour, asĂ como por la empresa propietaria de los terrenos donde se realizĂł el estudio. Este artĂculo se desarrollĂł en la zona de estudio del proyecto CP-IP 213968-2 IRIS, financiado por la European Union FP7, y la DirecciĂłn General de Industria, EnergĂa y Minas de la RegiĂłn de Murcia
Influence of the effect pigment size on the sparkle detection distance
5 pĂĄgs.; 5 figs.In an effort to create more dynamic looking automobiles, there is an ever increasing trend among automobile manufacturers towards the use of gonio-apparent coatings in car bodies. These coatings consist of transparent pigments mixed with metallic or interference flakes. The flakes in the coating cause a change in color and brightness of the finish with viewing and illumination direction. This change in appearance accentuates the 3D shading of a car body, making it visually more attractive. Besides this angular dependence on viewing/illumination direction, the metallic finishes also exhibit a visually complex texture. Depending on the properties of the finish and the viewing and illumination conditions, the flakes exhibit a sparkle like texture, while the glossy clear coat may show a rough or smooth surface. As a result of these complex visual attributes, capturing the appearance and finding a perfect color match for an automotive coating is a non trivial task. The main objective of this work is to evaluate the relationship between the special-effect pigments size, and the maximum distance which is detectable the sparkle texture effect. For this, two different sets of samples with different structural features were evaluated in a lighting booth specifically designed for the visual experiment. The booth allows to vary the lighting conditions, the viewing geometry and the distance at which the sample is perceived. The visual experiment was applied to evaluate the high correlation between a structural parameter (i.e. pigment size) and the visual appearance attribute related with texture (sparkle detection distance). Under some fixed environmental conditions, as light intensity, color temperature and geometry of the light source, the sparkle detection distance was evaluated by applying the adjustment psychophysical method for two panel sets (metallic grays and blues), with known pigment sizes and colorimetry, with a small set of observers. The visual results show that a greater the pigment size, a greater the sparkle detection, but with some considerations. In future, we will extend this method, even reinforced applying the statistical design of experiments (DOE), for understanding the relevance and interplay of structural (size, shape, concentration, orientation, etc.), environmental (illuminance level, color rendering, geometry, etc.) and colorimetric (dark vs. light background, chroma, etc.) factors on the sparkle detection distance. © 2015 Society for Imaging Science and Technology.Authors are grateful to EMRP for funding the project âMultidimensional reflectometry for industryâ. The EMRP is
jointly funded by the EMRP participating countries within EURAMET and the European Union. We would like to thank the
Ministry of Economy and Competitiveness for the coordinated project âNew developments in visual optics, vision and color
technologyâ (DPI2011-30090-C02). Omar GĂłmez would also like to thank the Ministry of Economy and Competitiveness for his pre-
doctoral fellowship grant (FPI BES-2012-053080).Peer Reviewe
Influencia del tamaño de pigmento en la distancia de detección del sparkle
XI ReuniĂłn Nacional de Ăptica DĂa de la Luz; Facultad de Ciencias âą Universidad de Salamanca 1 - 4 Septiembre, 2015; http://rno11.usal.es/programaSe diseñó un experimento psicofĂsico para evaluar la influencia del tamaño del
pigmento de efecto en la distancia de detecciĂłn del sparkle. Los resultados mostraron que a
mayor tamaño de pigmento, mayor distancia de detección. Ademås, la correlación visual e
instrumental (distancia de detecciĂłn vs. grado de sparkle (SG)) sigue una relaciĂłn lineal, sin
embargo, no existe una relación lineal con el tamaño de pigmento: la distancia es måxima
para un tamaño inferior al tamaño måximo.Peer Reviewe
Identification of gastrointestinal parasites by coproscopy in wild carnivores from the Parque de las Leyendas, Lima, Peru
El presente trabajo tuvo por objetivo identificar los parĂĄsitos gastrointestinales de carnĂvoros silvestres del ZoolĂłgico Parque de Las Leyendas en el PerĂș, mediante la aplicaciĂłn de cuatro mĂ©todos coproparasitolĂłgicos convencionales (directo, de Ritchie modificado, Sheather y la coloraciĂłn de Ziehl Neelsen). Se trabajĂł con 62 ejemplares pertenecientes a 17 especies de seis familias. El 25.8% (16/62) de las muestras fueron positivas a parĂĄsitos. Panthera leo, Panthera tigris y Lycalopex sechurae fueron las especies mĂĄs parasitadas (9/9, 2/3 y 3/5, respectivamente). Los parĂĄsitos identificados fueron el nematodo Toxascaris leonina (12/16), el acantocĂ©falo Corynosoma sp (3/16), el cestodo Atriotaenia sp (1/6) y el protozoo Giardia sp. (1/16). No se encontrĂł asociaciĂłn estadĂstica entre las variables de edad y sexo.The aim of this study was to identify gastrointestinal parasites in wild carnivores from the Parque de Las Leyendas Zoo in Peru by four conventional coproparasitological methods (direct, Ritchie modified Sheather and the Ziehl Neelsen method for coccidia). A total of 62 animals of 15 species from six families were sampled. Results showed that 25.8% (16/62) of the samples were positive to parasites. Panthera leo, Panthera tigris and Lycalopex sechurae were the most affected species (9/9, 2/3, and 3/5 respectively). The parasites identified were the nematode Toxascaris leonina (12/16), the acanthocephalan Corynosoma sp (3/16), the cestode Atriotaenia sp (1/6) and the protozoo Giardia sp (1/6). No significant association was found between the variables age and sex
CD8 T cells are dispensable for experimental autoimmune prostatitis induction and chronic pelvic pain development
Impact Factor: 5.5Fil: Salazar, Florencia C. Universidad Nacional de CĂłrdoba. Facultad de Ciencias QuĂmicas. Departamento de BioquĂmica ClĂnica, Argentina.Fil: Salazar, Florencia C. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro de Investigaciones en BioquĂmica ClĂnica e InmunologĂa, Argentina.Fil: MartĂnez, Maria S. Universidad Nacional de CĂłrdoba. Facultad de Ciencias QuĂmicas. Departamento de BioquĂmica ClĂnica, Argentina.Fil: MartĂnez, Maria S. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro de Investigaciones en BioquĂmica ClĂnica e InmunologĂa, Argentina.Fil: Paira, Daniela A. Universidad Nacional de CĂłrdoba. Facultad de Ciencias QuĂmicas. Departamento de BioquĂmica ClĂnica, Argentina.Fil: Paira, Daniela A. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro de Investigaciones en BioquĂmica ClĂnica e InmunologĂa, Argentina.Fil: Chocobar, Yair A. Universidad Nacional de CĂłrdoba. Facultad de Ciencias QuĂmicas. Departamento de BioquĂmica ClĂnica; Argentina.Fil: Chocobar, Yair A. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro de Investigaciones en BioquĂmica ClĂnica e InmunologĂa, Argentina.Fil: Olivera, Carolina. Universidad Nacional de CĂłrdoba. Facultad de Ciencias QuĂmicas. Departamento de BioquĂmica ClĂnica, Argentina.Fil: Olivera, Carolina. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro de Investigaciones en BioquĂmica ClĂnica e InmunologĂa, Argentina.Fil: Godoy, Gloria J. Universidad Nacional de CĂłrdoba. Facultad de Ciencias QuĂmicas. Departamento de BioquĂmica ClĂnica, Argentina.Fil: Godoy, Gloria J. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro de Investigaciones en BioquĂmica ClĂnica e InmunologĂa, Argentina.Fil: Acosta, RodrĂguez Eva V. Universidad Nacional de CĂłrdoba. Facultad de Ciencias QuĂmicas. Departamento de BioquĂmica ClĂnica, Argentina.Fil: Acosta, RodrĂguez Eva V. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro de Investigaciones en BioquĂmica ClĂnica e InmunologĂa, Argentina.Fil: Rivero, Virginia E. Universidad Nacional de CĂłrdoba. Facultad de Ciencias QuĂmicas. Departamento de BioquĂmica ClĂnica, Argentina.Fil: Rivero, Virginia E. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro de Investigaciones en BioquĂmica ClĂnica e InmunologĂa, Argentina.Fil: Motrich, RubĂ©n D. Universidad Nacional de CĂłrdoba. Facultad de Ciencias QuĂmicas. Departamento de BioquĂmica ClĂnica, Argentina.Fil: Motrich, RubĂ©n D. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro de Investigaciones en BioquĂmica ClĂnica e InmunologĂa, Argentina.Introduction: Chronic Pelvic Pain Syndrome or Chronic Prostatitis (CPPS/CP) is the most prevalent urologic affliction among young adult men. It is a challenging condition to treat, which significantly decreases patient quality of life, mostly because of its still uncertain aetiology. In that regard, an autoimmune origin is a prominent supported theory. Indeed, studies in patients and in rodent models of Experimental Autoimmune Prostatitis (EAP) have provided compelling evidence suggesting a key role of CD4 Th1 cells in disease pathogenesis. However, the implication of other prominent effectors of the immune system, such as CD8 T cells, has yet to be studied.
Methods: We herein analyzed the induction of prostatitis and the development of chronic pelvic pain in EAP using CD8 T cell-deficient animals.
Results: We found similarly elevated PA-specific immune responses, with high frequencies of specific IFNg+CD4+ and IL17+CD4+ T cells in prostate draining lymph nodes from PA-immunized either CD8 KO or wild type animals with respect to controls. Moreover, these peripheral immune responses were paralleled by the development of significant chronic pelvic pain, and accompanied by prostate histological lesions, characterized by hemorrhage, epithelial cell desquamation, marked periglandular leukocyte infiltration, and increased collagen deposition in both, PA-immunized CD8 KO and wild type animals. As expected, control animals did not develop prostate histological lesions.
Discussion: Our results indicate that CD8 T cells do not play a major role in EAP pathogenesis and chronic pelvic pain development. Moreover, our results corroborate the previous notion that a CD4 Th1 associated immune response drives the induction of prostate tissue inflammation and the development of chronic pelvic pain.info:eu-repo/semantics/publishedVersionFil: Salazar, Florencia C. Universidad Nacional de CĂłrdoba. Facultad de Ciencias QuĂmicas. Departamento de BioquĂmica ClĂnica, Argentina.Fil: Salazar, Florencia C. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro de Investigaciones en BioquĂmica ClĂnica e InmunologĂa, Argentina.Fil: MartĂnez, Maria S. Universidad Nacional de CĂłrdoba. Facultad de Ciencias QuĂmicas. Departamento de BioquĂmica ClĂnica, Argentina.Fil: MartĂnez, Maria S. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro de Investigaciones en BioquĂmica ClĂnica e InmunologĂa, Argentina.Fil: Paira, Daniela A. Universidad Nacional de CĂłrdoba. Facultad de Ciencias QuĂmicas. Departamento de BioquĂmica ClĂnica, Argentina.Fil: Paira, Daniela A. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro de Investigaciones en BioquĂmica ClĂnica e InmunologĂa, Argentina.Fil: Chocobar, Yair A. Universidad Nacional de CĂłrdoba. Facultad de Ciencias QuĂmicas. Departamento de BioquĂmica ClĂnica; Argentina.Fil: Chocobar, Yair A. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro de Investigaciones en BioquĂmica ClĂnica e InmunologĂa, Argentina.Fil: Olivera, Carolina. Universidad Nacional de CĂłrdoba. Facultad de Ciencias QuĂmicas. Departamento de BioquĂmica ClĂnica, Argentina.Fil: Olivera, Carolina. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro de Investigaciones en BioquĂmica ClĂnica e InmunologĂa, Argentina.Fil: Godoy, Gloria J. Universidad Nacional de CĂłrdoba. Facultad de Ciencias QuĂmicas. Departamento de BioquĂmica ClĂnica, Argentina.Fil: Godoy, Gloria J. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro de Investigaciones en BioquĂmica ClĂnica e InmunologĂa, Argentina.Fil: Acosta, RodrĂguez Eva V. Universidad Nacional de CĂłrdoba. Facultad de Ciencias QuĂmicas. Departamento de BioquĂmica ClĂnica, Argentina.Fil: Acosta, RodrĂguez Eva V. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro de Investigaciones en BioquĂmica ClĂnica e InmunologĂa, Argentina.Fil: Rivero, Virginia E. Universidad Nacional de CĂłrdoba. Facultad de Ciencias QuĂmicas. Departamento de BioquĂmica ClĂnica, Argentina.Fil: Rivero, Virginia E. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro de Investigaciones en BioquĂmica ClĂnica e InmunologĂa, Argentina.Fil: Motrich, RubĂ©n D. Universidad Nacional de CĂłrdoba. Facultad de Ciencias QuĂmicas. Departamento de BioquĂmica ClĂnica, Argentina.Fil: Motrich, RubĂ©n D. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro de Investigaciones en BioquĂmica ClĂnica e InmunologĂa, Argentina
3-Hydroxy Kynurenine Treatment Controls T. cruzi Replication and the Inflammatory Pathology Preventing the Clinical Symptoms of Chronic Chagas Disease
BACKGROUND: 3-Hydroxy Kynurenine (3-HK) administration during the acute phase of Trypanosoma. cruzi infection decreases the parasitemia of lethally infected mice and improves their survival. However, due to the fact that the treatment with 3-HK is unable to eradicate the parasite, together with the known proapoptotic and immunoregulatory properties of 3-HK and their downstream catabolites, it is possible that the 3-HK treatment is effective during the acute phase of the infection by controlling the parasite replication, but at the same time suppressed the protective T cell response before pathogen clearance worsening the chronic phase of the infection. Therefore, in the present study, we investigated the effect of 3-HK treatment on the development of chronic Chagas' disease. PRINCIPAL FINDINGS: In the present study, we treated mice infected with T. cruzi with 3-HK at day five post infection during 5 consecutive days and investigated the effect of this treatment on the development of chronic Chagas disease. Cardiac functional (electrocardiogram) and histopathological studies were done at 60 dpi. 3-HK treatment markedly reduced the incidence and the severity of the electrocardiogram alterations and the inflammatory infiltrates and fibrosis in heart and skeletal muscle. 3-HK treatment modulated the immune response at the acute phase of the infection impairing the Th1- and Th2-type specific response and inducing TGF-ÎČ-secreting cells promoting the emergence of regulatory T cells and long-term specific IFN-Îł secreting cells. 3-HK in vitro induced regulatory phenotype in T cells from T. cruzi acutely infected mice. CONCLUSIONS: Our results show that the early 3-HK treatment was effective in reducing the cardiac lesions as well as altering the pattern of the immune response in experimental Chagas' disease. Thus, we propose 3-HK as a novel therapeutic treatment able to control both the parasite replication and the inflammatory response
Fusion of 8He with 206Pb around Coulomb barrier energies
The experimental study of the fusion of light neutron-rich nucleus 8He with 206Pb is reported in this work. A fusion stack of 206Pb targets has been used for this study. The most prominent evaporation residue (210Po), which has half-life of 138 days and decays by alpha emission, is populated in the reaction. Radiochemical analysis technique is used to extract the yield of this evaporation residue.Ministerio de Ciencia e InnovaviĂłn FPA2007-63074European Union 21269
Data warehouse y data mining aplicados al estudio del rendimiento académico y de perfiles de alumnos
El desigual aprovechamiento de las TICs observado en los alumnos de Sistemas Operativos de la LSI de la FACENA de la UNNE, como asĂ tambiĂ©n el relativamente bajo porcentaje de alumnos promocionados y regularizados al finalizar el cursado de la Asignatura (Ă©xito acadĂ©mico), han motivado la aplicaciĂłn de tĂ©cnicas de Almacenes de Datos (DataWarehouses: DW) y de MinerĂa de Datos (Data Mining: DM) basadas en clustering, entre otras, para la bĂșsqueda de perfiles de los alumnos de la Asignatura mencionada, segĂșn su rendimiento acadĂ©mico, situaciĂłn demogrĂĄfica y socio econĂłmica, con el propĂłsito de determinar a priori situaciones potenciales de Ă©xito o de fracaso acadĂ©mico, lo cual permitirĂa encarar las medidas tendientes a minimizar los fracasos. El presente trabajo tiene por objetivo brindar una breve descripciĂłn de aspectos relacionados con el almacĂ©n de datos construido y algunos procesos de minerĂa de datos desarrollados sobre el mismo.Eje: Bases de datos y minerĂa de datosRed de Universidades con Carreras en InformĂĄtica (RedUNCI
Data warehouse y data mining aplicados al estudio del rendimiento académico y de perfiles de alumnos
El desigual aprovechamiento de las TICs observado en los alumnos de Sistemas Operativos de la LSI de la FACENA de la UNNE, como asĂ tambiĂ©n el relativamente bajo porcentaje de alumnos promocionados y regularizados al finalizar el cursado de la Asignatura (Ă©xito acadĂ©mico), han motivado la aplicaciĂłn de tĂ©cnicas de Almacenes de Datos (DataWarehouses: DW) y de MinerĂa de Datos (Data Mining: DM) basadas en clustering, entre otras, para la bĂșsqueda de perfiles de los alumnos de la Asignatura mencionada, segĂșn su rendimiento acadĂ©mico, situaciĂłn demogrĂĄfica y socio econĂłmica, con el propĂłsito de determinar a priori situaciones potenciales de Ă©xito o de fracaso acadĂ©mico, lo cual permitirĂa encarar las medidas tendientes a minimizar los fracasos. El presente trabajo tiene por objetivo brindar una breve descripciĂłn de aspectos relacionados con el almacĂ©n de datos construido y algunos procesos de minerĂa de datos desarrollados sobre el mismo.Eje: Bases de datos y minerĂa de datosRed de Universidades con Carreras en InformĂĄtica (RedUNCI
Data warehouse y data mining aplicados al estudio del rendimiento académico y de perfiles de alumnos
El desigual aprovechamiento de las TICs observado en los alumnos de Sistemas Operativos de la LSI de la FACENA de la UNNE, como asĂ tambiĂ©n el relativamente bajo porcentaje de alumnos promocionados y regularizados al finalizar el cursado de la Asignatura (Ă©xito acadĂ©mico), han motivado la aplicaciĂłn de tĂ©cnicas de Almacenes de Datos (DataWarehouses: DW) y de MinerĂa de Datos (Data Mining: DM) basadas en clustering, entre otras, para la bĂșsqueda de perfiles de los alumnos de la Asignatura mencionada, segĂșn su rendimiento acadĂ©mico, situaciĂłn demogrĂĄfica y socio econĂłmica, con el propĂłsito de determinar a priori situaciones potenciales de Ă©xito o de fracaso acadĂ©mico, lo cual permitirĂa encarar las medidas tendientes a minimizar los fracasos. El presente trabajo tiene por objetivo brindar una breve descripciĂłn de aspectos relacionados con el almacĂ©n de datos construido y algunos procesos de minerĂa de datos desarrollados sobre el mismo.Eje: Bases de datos y minerĂa de datosRed de Universidades con Carreras en InformĂĄtica (RedUNCI
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