212 research outputs found
Unrest at Domuyo Volcano, Argentina, detected by geophysical and geodetic data and morphometric analysis
New volcanic unrest has been detected in the Domuyo Volcanic Center (DVC), to the east of the Andes Southern Volcanic Zone in Argentina. To better understand this activity, we investigated new seismic monitoring data, gravimetric and magnetic campaign data, and interferometric synthetic aperture radar (InSAR) deformation maps, and we derived an image of the magma plumbing system and the likely source of the unrest episode. Seismic events recorded during 2017-2018 nucleate beneath the southwestern flank of the DVC. Ground deformation maps derived from InSAR processing of Sentinel-1 data exhibit an inflation area exceeding 300 km2, from 2014 to at least March 2018, which can be explained by an inflating sill model located 7 km deep. The Bouguer anomaly reveals a negative density contrast of ~35 km wavelength, which is spatially coincident with the InSAR pattern. Our 3D density modeling suggests a body approximately 4-6 km deep with a density contrast of -550 kg/m3. Therefore, the geophysical and geodetic data allow identification of the plumbing system that is subject to inflation at these shallow crustal depths. We compared the presence and dimensions of the inferred doming area to the drainage patterns of the area, which support long-established incremental uplift according to morphometric analysis. Future studies will allow us to investigate further whether the new unrest is hydrothermal or magmatic in origin.Fil: Astort, Ana. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Estudios Andinos "Don Pablo Groeber". Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Estudios Andinos "Don Pablo Groeber"; ArgentinaFil: Walter, Thomas R. German Research Centre for Geosciences; AlemaniaFil: Ruiz, Francisco. Universidad Nacional de San Juan. Facultad de Ciencias Exactas, Físicas y Naturales. Instituto Geofísico Sismológico Volponi; ArgentinaFil: Sagripanti, Lucía. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Estudios Andinos "Don Pablo Groeber". Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Estudios Andinos "Don Pablo Groeber"; ArgentinaFil: Nacif, Andres Antonio. Universidad Nacional de San Juan. Facultad de Ciencias Exactas, Físicas y Naturales. Instituto Geofísico Sismológico Volponi; ArgentinaFil: Acosta, Gemma. Universidad Nacional de San Juan. Facultad de Ciencias Exactas, Físicas y Naturales. Instituto Geofísico Sismológico Volponi; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Folguera Telichevsky, Andres. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Estudios Andinos "Don Pablo Groeber". Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Estudios Andinos "Don Pablo Groeber"; Argentin
Prevalence of Radiological Chronic Pancreatitis and Exocrine Pancreatic Insufficiency in Patients with Decompensated Liver Disease: Is Fecal Elastase Useful in This Setting?
Chronic pancreatitis; Decompensated cirrhosis; Micronutrient deficienciesPancreatitis crónica; Cirrosis descompensada; Deficiencias de micronutrientesPancreatitis crònica; Cirrosi descompensada; Deficiències de micronutrientsChronic alcohol consumption is a well-known etiological factor for both chronic pancreatitis (CP) and liver cirrhosis. However, there is discussion over how often these two entities are present together in the same patient. The main goal of our study is to establish the prevalence of CP and low fecal elastase (FE-1) in patients with decompensated liver disease (DLD). In addition, we aim to identify the demographic, epidemiological and clinical factors associated with EPI and CP in patients with decompensated liver cirrhosis. This was an observational single-center study including 119 consecutive patients hospitalized for acute decompensation of cirrhosis, mostly of alcoholic etiology. Patients underwent computed tomography (CT) or magnetic resonance imaging (MRI) to assess the radiological features of CP. We also performed two FE-1 tests and complete blood tests to assess the presence of exocrine pancreatic insufficiency (EPI) and nutritional status, including micronutrients. The results of our study show that 32 patients (26.9%) had low fecal elastase suggesting EPI and 11 (9.2%) had CP. Patients meeting radiological CP criteria had lower FE-1 than patients without CP. There were no statistically significant differences in micronutrient deficiencies according to the presence of CP or not. Likewise, we did not find any statistically significant differences in micronutrient deficiencies among patients with normal and low FE-1 indicative of EPI. FE-1 alone may not be suitable for assessing EPI in patients with acute DLD. Detecting co-existing pancreatic disease may be important in a subset of patients with DLD, when the FE-1 levels are significantly low, potentially suggestive of a pancreatic anomaly. Moreover, the clinical manifestations of EPI and CP are not useful in detecting CP in DLD patients. Likewise, CP cannot explain all causes of EPI in these patients
The subduction of the Copiapó aseismic ridge, is the causing of the formation of metallic minerals deposits in north of Chile and Argentina?
The results obtained in this work evince that the metallic mineral deposits located in the northern region of the Chilean-Pampean flat slab (in northern Chile and north-western Argentina), at approximately 27 300 S, would be related to the subduction of the Copiapo aseismic ridge. The analysis of the gravity anomalies and vertical gravity gradient allows inferring a deflection and truncation of the main trend of the Andean structures at the extrapolated zone of the Copiapo ridge beneath South America. Thus, the general NNE-trend of the Andean structures are rotated locally to an ENE-strike within the area of the Ojos del Salado e San Buena Ventura lineament. We explain that this anomalous behavior of the gravity derived anomalies is related to the deformational effects imprinted by the ridge subduction. Regions with a low subduction angle (<30 to horizontal) are related to large mineralization due to fluids released by dehydration of the subducting crust. In addition, a higher degree of mantle melting could be produced by a thicker oceanic crust. Therefore, we interpret that the processes associated to the subduction of the Copiapo aseismic ridge (emplaced on a thickened oceanic crust due to a local compensation of the seamounts) are the cause of formation and emplacement of big metallic mineral deposits in this region of Chile and Argentina.Fil: Gimenez, Mario Ernesto. Universidad Nacional de San Juan. Facultad de Ciencias Exactas, Físicas y Naturales. Instituto Geofísico Sismológico Volponi; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan; ArgentinaFil: Acosta, Gemma. Universidad Nacional de San Juan. Facultad de Ciencias Exactas, Físicas y Naturales. Instituto Geofísico Sismológico Volponi; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan; ArgentinaFil: Alvarez Pontoriero, Orlando. Universidad Nacional de San Juan. Facultad de Ciencias Exactas, Físicas y Naturales. Instituto Geofísico Sismológico Volponi; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan; ArgentinaFil: Pesce, Agustina. Universidad Nacional de San Juan. Facultad de Ciencias Exactas, Físicas y Naturales. Instituto Geofísico Sismológico Volponi; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan; ArgentinaFil: Lince Klinger, Federico Gustavo. Universidad Nacional de San Juan. Facultad de Ciencias Exactas, Físicas y Naturales. Instituto Geofísico Sismológico Volponi; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan; ArgentinaFil: Folguera Telichevsky, Andres. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Estudios Andinos "Don Pablo Groeber". Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Estudios Andinos "Don Pablo Groeber"; Argentin
Interpretation of the upper crust from potential field methods in the region of Payenia and Malargüe fold and trhust belt
Se llevó a cabo un estudio gravi-magnetométrico a escala cortical para caracterizar los depocentros andinos del borde noroeste de la Cuenca Neuquina, situados enla provincia geológica de Payenia. Para ello se efectuaron mediciones (2240 estaciones) tanto del campo gravitatorio como magnético, apoyadas en mediciones de GPS diferencial (DGPS), valores de campo que fueron sumados a la extensa base de datos con la que cuenta el Instituto Geofísico Sismológico Volponi (IGSV). Se incorporaron datos de relevamientos aeromagnéticos suministrados por YPF S.A para cubrir las zonas sin datos terrestres. Se prepararon modelos 2D y 3D de inversión gravimétrica, con énfasis en la resolución de estructuras ubicas al este de la sierra de Palauco. Un modelo 3D de tres capas, apoyado en densidades de afloramientos y en valores de densidad de un pozo de exploración, permitió identificar con buena resolución geométrica altos y bajos estructurales del basamento y una subcuenca no reportada hasta el presente, en el borde este de la faja plegada y corrida de Malargüe y que se acuña con los afloramientos del basamento cristalino del bloque de San Rafael. Se modeló una sección gravimétrica de detalle que brinda información 2D de la estructura del mismo, especialmente al este de la sierra de Palauco donde se observa una profundización del relleno sedimentario. El espesor de la cubierta volcánico-clástica de este depocentro presenta su máximo hacia el este acuñándose bajo el bloque San Rafael.Different geophysical techniques, such as the potential field methods, were applied to characterize Andean depocenters along the northwestern border of the Neuquén basin, in the Payenia geological province. Around of 2240 new Differential Global Positioning System (DGPS) values supported gravimetric and magnetometric measurements were complemented with over 10000 gravity values from several survey campaigns carried out by researchers from the Volponi Geophysics and Seismological Institute through the last three decades. Additionally digital data from aeromagnetic reports by Servicio Geológico Minero Argentino (SEGEMAR) were provided by YPF S.A. Gravimetric and magnetometric maps were constructed to study the upper crustal sources. 2D and 3D inversion gravimetric models were prepared integrating geologic and geophysical information, with an emphasis in the resolution of structures placed to the east of Palauco. The 3D model of crystalline basement based on the average density values from a local well played a key role in identifying structural highs and lows structures already studied by other authors as well as a sub basin not yet reported. The detailed profile gives information about the 2D depocenter structure, showing a deepening and filling which wedges into a raised basement block belonging to San Rafael block. The volcanic-clastic infill of the newly reported depocenter reaches a maximum thickness of up to 4000 meters.Fil: Anci Araniti, Sheila Anabel. Universidad Nacional de San Juan. Facultad de Ciencias Exactas, Físicas y Naturales. Instituto Geofísico Sismológico Volponi; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Ruiz, Francisco. Universidad Nacional de San Juan. Facultad de Ciencias Exactas, Físicas y Naturales. Instituto Geofísico Sismológico Volponi; ArgentinaFil: Lince Klinger, Federico Gustavo. Universidad Nacional de San Juan. Facultad de Ciencias Exactas, Físicas y Naturales. Instituto Geofísico Sismológico Volponi; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Leiva, Maria Flavia. Universidad Nacional de San Juan. Facultad de Ciencias Exactas, Físicas y Naturales. Instituto Geofísico Sismológico Volponi; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Garcia, Hector Pedro Antonio. Universidad Nacional de San Juan. Facultad de Ciencias Exactas, Físicas y Naturales. Instituto Geofísico Sismológico Volponi; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Acosta, Gemma. Universidad Nacional de San Juan. Facultad de Ciencias Exactas, Físicas y Naturales. Instituto Geofísico Sismológico Volponi; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin
Crustal structure and continent‐ocean boundary along the Galicia continental margin (NW Iberia): insights from combined gravity and seismic interpretation
The magma‐poor rifted continental margin of Galicia has an extremely complex structure. Its formation involved several rifting episodes that occurred ultimately during the early Cretaceous near a ridge triple junction, which produced a change in the orientation of the main structures in its transition to the north Iberia margin. In addition, there is a superimposed partial tectonic inversion along its northwest and northern border which developed from the Late Cretaceous to at least Oligocene times. The present study integrates a large volume of new geophysical information (mainly marine gravity data and 2D seismic reflection profiles) to provide insights on the formation of this rift system and on the development of its later inversion. The combined interpretation and modeling of this data enable the presentation of a new crustal and structural domains map for the whole Galicia margin. This includes the rift domains related to the extreme thinning of the crust and the lithospheric mantle (stretched, necking, and hyperextension and mantle exhumation (HME) domains), as well as a domain of intense compressional deformation. New constraints arise on the origin, the deep structure, and the characterization of the along‐ and across‐strike variation of the continent‐ocean transition of the margin, where a progressive change from hyperextension to partial inversion is observed. The development of both rifting and later partial tectonic inversion is influenced by the existence of former first‐order tectonic features. Most of the tectonic inversion is focused on the HME domain, which in some areas of the northwestern margin is completely overprinted by compressional deformation
An Investigation into the Protein Composition of the Teneral Glossina morsitans morsitans Peritrophic Matrix.
BACKGROUND
Tsetse flies serve as biological vectors for several species of African trypanosomes. In order to survive, proliferate and establish a midgut infection, trypanosomes must cross the tsetse fly peritrophic matrix (PM), which is an acellular gut lining surrounding the blood meal. Crossing of this multi-layered structure occurs at least twice during parasite migration and development, but the mechanism of how trypanosomes do so is not understood. In order to better comprehend the molecular events surrounding trypanosome penetration of the tsetse PM, a mass spectrometry-based approach was applied to investigate the PM protein composition using Glossina morsitans morsitans as a model organism.
METHODS
PMs from male teneral (young, unfed) flies were dissected, solubilised in urea/SDS buffer and the proteins precipitated with cold acetone/TCA. The PM proteins were either subjected to an in-solution tryptic digestion or fractionated on 1D SDS-PAGE, and the resulting bands digested using trypsin. The tryptic fragments from both preparations were purified and analysed by LC-MS/MS.
RESULTS
Overall, nearly 300 proteins were identified from both analyses, several of those containing signature Chitin Binding Domains (CBD), including novel peritrophins and peritrophin-like glycoproteins, which are essential in maintaining PM architecture and may act as trypanosome adhesins. Furthermore, 27 proteins from the tsetse secondary endosymbiont, Sodalis glossinidius, were also identified, suggesting this bacterium is probably in close association with the tsetse PM.
CONCLUSION
To our knowledge this is the first report on the protein composition of teneral G. m. morsitans, an important vector of African trypanosomes. Further functional analyses of these proteins will lead to a better understanding of the tsetse physiology and may help identify potential molecular targets to block trypanosome development within the tsetse
EL DESARROLLO DE LA CREATIVIDAD Y LA INNOVACIÓN: SU APLICACIÓN EN EL AULA EN EL ÚLTIMO AÑO DEL GRADO EN ADMINISTRACIÓN Y DIRECCIÓN DE EMPRESAS DE LA UNIVERSIDAD POLITÉCNICA DE VALENCIA
[ES] Cada vez más la sociedad, la empresa, demanda un nuevo tipo de empleado: una persona innovadora. Personas que sean capaces de generar ideas , que provengan de más de un campo del conocimiento o que sean expertos en varios campos, que disfruten con el trabajo innovador, colaborativas, con capacidad para resolver problemas y que encuentren nuevas formas enfoques y maneras de ver las cosas.
El tiempo en que nos ha tocado vivir está marcado por los cambios estructurales: La globalización, el aumento de competencia, los cambios organizacionales y las nuevas tecnologías; la economía del conocimiento, el sistema de I+D y la formación. Por todo ello se considera la innovación como un elemento de la competitividad territorial.
Desde el aula, el profesor tiene un trabajo que realizar, también es un trabajo creativo e innovador y no es otro que fomentar el entrenamiento y desarrollo de esas capacidades y habilidades a través de grupos de trabajo que se enriquezcan y complementen. La gestión de la creatividad y de la innovación, estudia el papel que juega el profesor, en su faceta de entrenador, para desarrollar la creatividad en el aula ofreciendo consejos de lo que puede ser una innovación exitosa.
Por lo tanto esta justificada esta comunicación que va a explicar que hacemos en el aula para motivar e incentivar la innovación y la creatividad con la finalidad de que el alumno se encuentre mejor preparado para afrontar su integración en el mercado laboral.Herrero Blasco, A.; Grau Gadea, GF.; Osorio Acosta, E.; Peña Martinez, G. (2015). EL DESARROLLO DE LA CREATIVIDAD Y LA INNOVACIÓN: SU APLICACIÓN EN EL AULA EN EL ÚLTIMO AÑO DEL GRADO EN ADMINISTRACIÓN Y DIRECCIÓN DE EMPRESAS DE LA UNIVERSIDAD POLITÉCNICA DE VALENCIA. En Open Innovation & Coolhunting in education: INNODOCT'15 : International Conference on Innovation, Documentation and Teaching Technologies, held on-line in Valencia, Spain, on 12-15 May, 2013. Editorial de la Universitat Politècnica de València. 485-490. doi:10.4995/INNODOCT.2015.1030S48549
PROPUESTA PARA LA INCORPORACIÓN DE LAS COMPETENCIAS EN EL DISEÑO DE UN PROGRAMA DE PRÁCTICAS TRANSVERSAL PARA LAS TITULACIONES DE CIENCIAS SOCIALES Y JURÍDICAS DE LA UNIVERSITAT POLITÈCNICA DE VAÈNCIA
[ES] La orientación académica actual hacia la enseñanza por competencias enfatiza una serie de carencias que se vienen observando en el desarrollo de las prácticas en empresa curriculares en la formación superior. La inclusión en los programas de estudio de materias que inciden en la aplicación profesional del conocimiento trasciende, en la mayoría de las ocasiones, el ámbito propio de la Universidad. La responsabilidad de la pre-adaptación a la etapa profesional se traslada así a la sociedad. La búsqueda del pragmatismo y la utilidad inmediata en las empresas y organizaciones receptoras de estudiantes contrasta a menudo con la necesidad de dotar de coherencia a los nuevos modelos que necesariamente han de surgir de las relaciones universidad-empresa resultantes de los enfoques académicos actuales.
En este trabajo se plantea la hipótesis del diseño de un programa de prácticum multidisciplinar para el desarrollo de las competencias transversales a los grados en Administración y Dirección de Empresas (ADE), Gestión y Administración Pública (GAP) y Turismo (GGT). El planteamiento que se expone se centra en la fase de conceptualización de este nuevo enfoque de experiencia formativa. Se pretende que el modelo final, previa frase de contraste y prueba, se caracterice por su aplicabilidad inmediata en el ámbito de los programas de prácticas en empresas que se están desarrollando actualmente en la Universitat Politècnica de València.Osorio Acosta, E.; Teruel Serrano, MD.; Peña Martinez, G.; Herrero Blasco, A. (2015). PROPUESTA PARA LA INCORPORACIÓN DE LAS COMPETENCIAS EN EL DISEÑO DE UN PROGRAMA DE PRÁCTICAS TRANSVERSAL PARA LAS TITULACIONES DE CIENCIAS SOCIALES Y JURÍDICAS DE LA UNIVERSITAT POLITÈCNICA DE VAÈNCIA. En Open Innovation & Coolhunting in education: INNODOCT'15 : International Conference on Innovation, Documentation and Teaching Technologies, held on-line in Valencia, Spain, on 12-15 May, 2013. Editorial de la Universitat Politècnica de València. 412-421. doi:10.4995/INNODOCT.2015.54941242
Rendered-protein hydrolysates as a low-cost nitrogen source for the fungal biotransformation of 5-hydroxymethylfurfural
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Rendered-Protein Hydrolysates as a Low-Cost Nitrogen Source for the Fungal Biotransformation of 5-Hydroxymethylfurfural
by Diana Cosovanu
1, Alberto Millán Acosta
1, Pau Cabañeros López
2, Krist V. Gernaey
2 [ORCID] , Qian Li
3, Rene Lametsch
3, Ramon Canela-Garayoa
1 [ORCID] , Jordi Eras
1 [ORCID] and Gemma Villorbina
1,* [ORCID]
1
Chemistry Department, University of Lleida, Alcalde Rovira Roure 191, 25198 Lleida, Spain
2
Process and Systems Engineering Center (PROSYS), Department of Chemical and Biochemical Engineering, Technical University of Denmark, Building 228 A, 2800 Lyngby, Denmark
3
Department of Food Science, University of Copenhagen, 1958 Frederiksberg C, Denmark
*
Author to whom correspondence should be addressed.
Catalysts 2022, 12(8), 839; https://doi.org/10.3390/catal12080839
Received: 9 June 2022 / Revised: 19 July 2022 / Accepted: 21 July 2022 / Published: 30 July 2022
(This article belongs to the Special Issue Enzyme Catalysis, Biotransformation and Bioeconomy)
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Abstract
5-hydroxymethylfurfural (HMF) is a platform chemical that can be converted into a wide range of high-value derivatives. Industrially, HMF-based derivatives are synthesized via chemical catalysis. However, biocatalytic transformation has emerged as an attractive alternative. Significant advances have been made in the last years using isolated enzymes and whole-cell biocatalysts in HMF biotransformation. Nonetheless, one of the major bottlenecks is the cost of the process, mainly due to the microorganism growth substrate. In this work, biotransformation studies to transform HMF into 2,5-di(hydroxymethyl)furan (DHMF) were carried out with the fungus Fusarium striatum using low-cost protein hydrolysates. The protein hydrolysates were obtained from fines, an unexploited material produced during the rendering process of meat industry waste residues. Given the high content in the protein of fines, of around 46%, protein hydrolysis was optimized using two commercially available proteases, Alcalase 2.4 L and Neutrase 0.8 L. The maximum degree of hydrolysis (DH) achieved with Alcalase 2.4 L was 21.4% under optimal conditions of 5% E/S ratio, pH 8, 55 °C, and 24 h. On the other hand, Neutrase 0.8 L exhibited lower efficiency, and therefore, lower protein recovery. After optimization of the Neutrase 0.8 L process using the response surface methodology (RSM), the maximum DH achieved was 7.2% with the variables set at 15% E/S ratio, initial pH 8, 40 °C, and 10.5 h. Using these hydrolysates as a nitrogen source allowed higher sporulation of the fungus and, therefore, the use of a lower volume of inoculum (three-fold), obtaining a DHMF yield > 90%, 50% higher than the yield obtained when using commercial peptones. The presented process allows the transformation of animal co- and by-products into low-cost nitrogen sources, which greatly impacts the industrial feasibility of HMF biotransformation.This research was funded by the Spanish Ministry of Science and Innovation PID2019110735RB-C21, by the Catalan government, 2017 SGR 828, and by the University of Lleida "Ajuts per a personal predoctoral de la UdL en formacio i ajuts Jade Plus" awarded to Diana Cosovanu
Informe Técnico Preliminar. Reanálisis del Procesamiento Digital de Datos Satelitales - Sismo Provincia de San Juan 18 de enero de 2021
Fil: Carballo, F. Servicio Geológico Minero Argentino. Instituto de Geología y Recursos Minerales; Argentina.Fil: Pardo Duró, M.L. Servicio Geológico Minero Argentino. Instituto de Geología y Recursos Minerales; Argentina.Fil: Wright, E. Servicio Geológico Minero Argentino. Instituto de Geología y Recursos Minerales; Argentina.Fil: Heredia, M.S. Servicio Geológico Minero Argentino. Instituto de Geología y Recursos Minerales; Argentina.Fil: Acosta, G. Servicio Geológico Minero Argentino. Instituto de Geología y Recursos Minerales; Argentina
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