192 research outputs found

    I only have eyes for you: Ovulation redirects attention (but not memory) to attractive men

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    A number of studies have found a disjunction between women’s attention to, and memory for, handsome men. Although women pay initial attention to handsome men, they do not remember those men later. The present study examines how ovulation might differentially affect these attentional and memory processes. We found that women near ovulation increased their visual attention to attractive men. However, this increased visual attention did not translate into better memory. Discussion focuses on possible explanations, in the context of an emerging body of findings on disjunctions between attention to, and memory for, other people.National Institute of Mental Health (U.S.) (R01MH064734

    Evaluating Models' Response of Tropical Low Clouds to SST Forcings Using CALIPSO Observations

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    Recent studies have shown that, in response to a surface warming, the marine tropical low-cloud cover (LCC) as observed by passive-sensor satellites substantially decreases, therefore generating a smaller negative value of the top-of-the-atmosphere (TOA) cloud radiative effect (CRE). Here we study the LCC and CRE interannual changes in response to sea surface temperature (SST) forcings in the GISS model E2 climate model, a developmental version of the GISS model E3 climate model, and in 12 other climate models, as a function of their ability to represent the vertical structure of the cloud response to SST change against 10 years of CALIPSO (Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observations) observations. The more realistic models (those that satisfy the observational constraint) capture the observed interannual LCC change quite well ([delta]LCC]/[delta]SST= -3.491.01%K [negative 1 superscript] vs. [delta]LCC/[delta]SST[subscript obs]= -3.590.28%K[negative 1 superscript]) while the others largely underestimate it ([delta]LCC/[delta]SST= -1.321.28%K[negative 1 superscript]). Consequently, the more realistic models simulate more positive shortwave (SW) feedback ([delta]CRE/[delta]SST=2.601.13Wm[negative 2 superscript] K[negative 1 superscript]) than the less realistic models (CRE/SST=0.872.63Wm2K1), in better agreement with the observations ([delta]CRE/[delta]SST[subscript obs]=30.26Wm[negative 2 superscript] K[negative 1 superscript] ), although slightly underestimated. The ability of the models to represent moist processes within the planetary boundary layer (PBL) and produce persistent stratocumulus (Sc) decks appears crucial to replicating the observed relationship between clouds, radiation and surface temperature. This relationship is different depending on the type of low clouds in the observations. Over stratocumulus regions, cloud-top height increases slightly with SST, accompanied by a large decrease in cloud fraction, whereas over trade cumulus (Cu) regions, cloud fraction decreases everywhere, to a smaller extent

    The narcissistic mask: An exploration of \u27the defensive grandiosity hypothesis\u27

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    Narcissism has been conceptualized as involving attempts to defend against negative self-schemata (implicit negative beliefs about one\u27s own self-worth). This idea has been termed the \u27mask model of narcissism\u27. This study explores the mask model, examining the association between extreme narcissistic personality traits and performance on a task purported to assess the influence of negative self-schemata. Participants (n=232) from the UK and the UAE completed the Narcissistic Personality Inventory and also performed an incidental learning task involving the surprise recall of self-referential adjectives (traits). A greater recall of negative adjectives was viewed as indicative of negative self-schemata. Looking at the sample as a whole, there were no associations between narcissistic traits and negative adjective recall. However, amongst those scoring in the upper quartile of the Narcissistic Personality Inventory, narcissism scores were positively correlated with the recall of negative adjectives even after controlling for age and memory. Narcissism may reflect self-enhancement strategies rooted in negative self-beliefs. © 2012 John Wiley & Sons, Ltd

    Radiative Flux and Forcing Parameterization Error in Aerosol-Free Clear Skies

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    This article reports on the accuracy in aerosol- and cloud-free conditions of the radiation parameterizations used in climate models. Accuracy is assessed relative to observationally validated reference models for fluxes under present-day conditions and forcing (flux changes) from quadrupled concentrations of carbon dioxide. Agreement among reference models is typically within 1 W/m2, while parameterized calculations are roughly half as accurate in the longwave and even less accurate, and more variable, in the shortwave. Absorption of shortwave radiation is underestimated by most parameterizations in the present day and has relatively large errors in forcing. Error in present-day conditions is essentially unrelated to error in forcing calculations. Recent revisions to parameterizations have reduced error in most cases. A dependence on atmospheric conditions, including integrated water vapor, means that global estimates of parameterization error relevant for the radiative forcing of climate change will require much more ambitious calculations

    Intertidal No. 1

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    For the first year ever, Intertidal has surfaced to showcase the art of Cal Poly\u27s students and faculty. An \u27intertidal zone\u27 is an area where the ocean meets the land--hidden during the high tide and exposed during the low. Our journal embodies the moment where the tide recedes, revealing stories previously hidden

    A Vicious Tenacity: The Efficiency Strategy Confronted With the Rebound Effect

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    Studies of the phenomena known as the “rebound effect,” “backfire,” and the “Jevons Paradox” have cast doubt on the effectiveness, in terms of reduction of energy use, of measures based on efficiency gains. Some of them have shown that efficiency improvements are less effective than expected, others have lent strength to the hypothesis that efficiency improvements are counterproductive in the long run. The difference between the two groups is thus all but negligible. Moreover, it is of considerable pragmatic significance as it may undermine the foundations of solid expectations that had led to ongoing systems and repertoires of action. In this paper we provide a model about the hypothesis that the expectations related to the effects that efficiency gains have on energy and resource consumption may exacerbate the rebound effect and that they prevent alternative strategies, that may turn out to be more effective in reducing energy and resource use, to be enacted. In the concluding paragraph, we propose possibilities for further hypothesis and empirical research that could lead to the refinement of the model

    IgG and Fcγ Receptors in Intestinal Immunity and Inflammation.

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    Fcγ receptors (FcγR) are cell surface glycoproteins that mediate cellular effector functions of immunoglobulin G (IgG) antibodies. Genetic variation in FcγR genes can influence susceptibility to a variety of antibody-mediated autoimmune and inflammatory disorders, including systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). More recently, however, genetic studies have implicated altered FcγR signaling in the pathogenesis of inflammatory bowel disease (IBD), a condition classically associated with dysregulated innate and T cell immunity. Specifically, a variant of the activating receptor, FcγRIIA, with low affinity for IgG, confers protection against the development of ulcerative colitis, a subset of IBD, leading to a re-evaluation of the role of IgG and FcγRs in gastrointestinal tract immunity, an organ system traditionally associated with IgA. In this review, we summarize our current understanding of IgG and FcγR function at this unique host-environment interface, from the pathogenesis of colitis and defense against enteropathogens, its contribution to maternal-fetal cross-talk and susceptibility to cancer. Finally, we discuss the therapeutic implications of this information, both in terms of how FcγR signaling pathways may be targeted for the treatment of IBD and how FcγR engagement may influence the efficacy of therapeutic monoclonal antibodies in IBD

    Prolyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses.

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    Fully activated innate immune cells are required for effective responses to infection, but their prompt deactivation and removal are essential for limiting tissue damage. Here, we have identified a critical role for the prolyl hydroxylase enzyme Phd2 in maintaining the balance between appropriate, predominantly neutrophil-mediated pathogen clearance and resolution of the innate immune response. We demonstrate that myeloid-specific loss of Phd2 resulted in an exaggerated inflammatory response to Streptococcus pneumonia, with increases in neutrophil motility, functional capacity, and survival. These enhanced neutrophil responses were dependent upon increases in glycolytic flux and glycogen stores. Systemic administration of a HIF-prolyl hydroxylase inhibitor replicated the Phd2-deficient phenotype of delayed inflammation resolution. Together, these data identify Phd2 as the dominant HIF-hydroxylase in neutrophils under normoxic conditions and link intrinsic regulation of glycolysis and glycogen stores to the resolution of neutrophil-mediated inflammatory responses. These results demonstrate the therapeutic potential of targeting metabolic pathways in the treatment of inflammatory disease.This work was principally supported by a Wellcome Trust Senior Clinical Fellowship award (098516 to SRW), Medical Research Council (MRC) Clinical Training Fellowship awards (G0802255 to AART; MR/K023845/1 to RSD), an Academy of Medical Sciences (AMS) starter grant (to AART), a Wellcome Trust Senior Clinical Fellowship award (076945 to DHD), British Lung Foundation Fellowship (F05/7 to HMM), and a Engineering and Physical Sciences Research Council and Medical Research Council grant (EP/L016559/1, JAW). The MRC /University of Edinburgh Centre for Inflammation Research is supported by an MRC Centre Grant. The work of PC is supported by long-term structural funding-Methusalem funding from the Flemish Government. CJS thanks the Wellcome Trust and Cancer Research UK for support
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