7,030 research outputs found

    More is Less: Perfectly Secure Oblivious Algorithms in the Multi-Server Setting

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    The problem of Oblivious RAM (ORAM) has traditionally been studied in a single-server setting, but more recently the multi-server setting has also been considered. Yet it is still unclear whether the multi-server setting has any inherent advantages, e.g., whether the multi-server setting can be used to achieve stronger security goals or provably better efficiency than is possible in the single-server case. In this work, we construct a perfectly secure 3-server ORAM scheme that outperforms the best known single-server scheme by a logarithmic factor. In the process, we also show, for the first time, that there exist specific algorithms for which multiple servers can overcome known lower bounds in the single-server setting.Comment: 36 pages, Accepted in Asiacrypt 201

    Multiplex cytokine analysis of dermal interstitial blister fluid defines local disease mechanisms in systemic sclerosis.

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    Clinical diversity in systemic sclerosis (SSc) reflects multifaceted pathogenesis and the effect of key growth factors or cytokines operating within a disease-specific microenvironment. Dermal interstitial fluid sampling offers the potential to examine local mechanisms and identify proteins expressed within lesional tissue. We used multiplex cytokine analysis to profile the inflammatory and immune activity in the lesions of SSc patients

    Introduction to Paleontology Research through the Boudreaux Bend Project

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    https://scholarworks.moreheadstate.edu/student_scholarship_posters/1058/thumbnail.jp

    The clinicopathological spectrum and driver mutation profile in classic BCR-ABL1 negative myeloproliferative neoplasms: a three-year study from a tertiary care center in Kerala, South India

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    Background: Myeloproliferative neoplasms (MPNs) are clonal hematopoietic stem cell disorders primarily of the adults. The 2016 World Health Organization (WHO) classification of MPNs include the molecular landscape as one of the diagnostic criteria. JAK2 exon14 (JAK2 V617F), JAK2 exon12, Myeloproliferative leukemia virus oncogene exon 10 (MPL 515), and calreticulin exon 9 (CALR) mutations are the main somatic driver mutations detected in classic BCR-ABL1 negative MPNs. Methods: A retrospective, cross-sectional study was conducted including 99 patients diagnosed with classic BCR-ABL1 negative MPNs during a 3-year time period, from March 2018 to February 2021 in the departments of pathology and clinical haematology- haemato oncology of a tertiary care teaching hospital. Clinical, haematological and morphological features were analysed and correlated with MPN associated mutation studies done in blood/bone marrow samples. Results: The prevalence of polycythaemia vera (PV) was found to be higher than other MPN, two third of which were JAK2 positive. More than half of the cases of primary myelofibrosis (PMF) and essential thrombocythemia (ET) also showed JAK2 mutation. CALR was positive in 17.4% of ET and 31.3% of PMF; MPL in 4.4% of ET and 3.1% of PMF. Conclusions: The prevalence of triple-negative MPN point towards the need for whole-exome sequencing of triple-negative MPN

    Self-organized critical neural networks

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    A mechanism for self-organization of the degree of connectivity in model neural networks is studied. Network connectivity is regulated locally on the basis of an order parameter of the global dynamics which is estimated from an observable at the single synapse level. This principle is studied in a two-dimensional neural network with randomly wired asymmetric weights. In this class of networks, network connectivity is closely related to a phase transition between ordered and disordered dynamics. A slow topology change is imposed on the network through a local rewiring rule motivated by activity-dependent synaptic development: Neighbor neurons whose activity is correlated, on average develop a new connection while uncorrelated neighbors tend to disconnect. As a result, robust self-organization of the network towards the order disorder transition occurs. Convergence is independent of initial conditions, robust against thermal noise, and does not require fine tuning of parameters.Comment: 5 pages RevTeX, 7 figures PostScrip

    A bias in optical observations of high redshift luminous infrared galaxies

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    We present evidence for the dramatically different morphology between the rest frame UV and 7micron mid-IR emission of VV114 and Arp299, two nearby (z~0) violently interacting infrared luminous galaxies (LIRGs). Nearly all LIRGs are interacting systems and it is currently accepted that they dominate the IR emission at z>1. Luminous IR galaxies located at z=1-2 could easily be detected as unresolved sources in deep optical/near-IR ground based surveys, as well as in upcoming 24micron surveys with the Space Infrared Telescope Facility. We demonstrate that the spatial resolution of these surveys will result in blending of the emission from unresolved interacting components. An increased scatter will thus be introduced in the observed optical to mid-IR colors of these galaxies, leading to a systematic underestimation of their dust content.Comment: To appear in the Astrophysical Journal Letters (4 pages 1 figure

    Simulations of Solid-on-Solid Models of Spreading of Viscous Droplets

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    We have studied the dynamics of spreading of viscous non-volatile fluids on surfaces by MC simulations of SOS models. We have concentrated on the complete wetting regime, with surface diffusion barriers neglected for simplicity. First, we have performed simulations for the standard SOS model. Formation of a single precursor layer, and a density profile with a spherical cap shaped center surrounded by Gaussian tails can be reproduced with this model. Dynamical layering (DL), however, only occurs with a very strongly attractive van der Waals type of substrate potential. To more realistically describe the spreading of viscous liquid droplets, we introduce a modified SOS model. In the new model, tendency for DL and the effect of the surface potential are in part embedded into the dynamics of the model. This allows a relatively simple description of the spreading under different conditions, with a temperature like parameter which strongly influences the droplet morphologies. Both rounded droplet shapes and DL can easily be reproduced with the model. Furthermore, the precursor width increases proportional to the square root of time, in accordance with experimental observations. PACS: 68.10.Gw, 05.70.Ln, 61.20.Ja.Comment: to appear in Physica A (1994), standard LaTex, 20 page
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