Effects of different pest managements on biodiversity of insects in citrus orchards of Babolsar and Hadishahr districts in Iran

In this research, insect populations in citrus orchards of Hadishahr, Babolsar, Mazandaran Province, Iran, under different types of pest management including conventional orchard (CO), low input orchard (LIO) and free pesticides protocol orchard (FPPO) in winter and spring seasons during December 22, 2017 to June 21, 2018 were evaluated by installation of pitfall traps, sticky yellow cards and branch and leaf samples. The results on foliage samples in winter showed that the highest Shanon-Weiner index, Brilloun index, species richness and species frequency was obtained for LIO. In spring, the highest values of diversity indices, species richness and frequency was also calculated for LIO. The highest eveness indices was obtained for CO in winter and spring. Mean comparisons on data collected by sticky yellow cards showed that in winter and spring, the highest values of diversity indices, species richness and frequency was estimated for LIO, while in winter, the values of eveness indices for CO was significantly more than those for FPPO and LIO, and in spring, the highest values of eveness indices belonged to FPPO. Based on the results related to pitfall traps, the highest values of diversity indices, species richness and frequency was obtained for LIO, while the values of eveness indices calculated for CO was higher than those for FPPO and LIO

The Effect of Myricetin Flavonoid on the Expression of Fyn Gene in Melanoma Cells (A375)

Background: Malignant melanoma as one of the most common cancers is currently spreading worldwide. Regarding after-effect of advanced treatments, using natural products has attracted much attention. Flavonoids, polyphenol compounds rich in diet, are being considered for their therapeutic preventive features. Fyn gene, a member of the protein tyrosine kinase oncogene family, has become an important target for therapy goals. Objectives: The aim of this study was to assess Fyn gene expression after treatment of melanoma cells with myricetin. Methods: In this study, the melanoma cells were treated with different concentrations of myricetin (0 to 100 �M) and their viability was determined by the methylthiazolyl diphenyl-tetrazolium bromide (MTT) assay, also the expression of Fyn gene in treated cells with selected concentrations of myricetin (0, 20, 40, 50, and 60 �M) was detected by real time quantitative polymerase chain reaction (qPCR). Results: The current investigation showed that treatment of A375 melanoma cells with the dietary flavonoid myricetin (3, 5, 7- trihydroxy-2-(3, 4, 5,-trihydroxy phenyl)-4- chromenone), resulted in decreased cell viability and increased expression of Fyn gene. The MTT assay analysis of exposed cells with different concentrations of myricetin showed that up to 25 �Mof myricetin had no cytotoxicity effect on A375 cells, also with increasing of myricetin concentration, the repression of cell proliferation developed as well. Conclusions: Real time qPCR analysis of Fyn expression in exposed cells with various concentration of myricetin leads to overexpression of this gene, dose dependently. Through this research, it was determined that myricetin with its anti-proliferative potential could suppress the development of cancer cells. On the other hand, since Fyn kinase could be involved in tumorigenesis of some cancer cells, it could be concluded that myricetin could effect the carcinogenicity of Fyn function in melanoma cells. Keywords: Melanoma, A375, Myricetin, Fyn Gen

The evaluation of physical properties of a polyurethane expandable endodontic sealer: a preliminary study

Endodontic sealers play a vital role in providing 3-dimensional (3D) filling of complex root canal system (RCS). This study intended to compare the physical properties of a Polyurethane Expandable Sealer (PES), AH Plus and EndoSequence. Three properties including setting time, radiopacity and flow (rheology) were evaluated based on ISO 6876 standard. For evaluation of each of these physical properties, five samples from experimental groups: AH Plus, EndoSequence, PES (controlled expansion) and PES (high expansion) were used (n = 5). Data were analysed by one-way ANOVA and Post Hoc Tukey tests (a = 0.05). EndoSequence showed the longest setting time (P \u3c 0.000); AH Plus showed that highest radiopacity (P \u3c 0.000); and PES (high expansion) showed the highest flow (diameter and surface area) (P \u3c 0.000). EndoSequence and PES (controlled expansion) showed promising and comparable physical properties to the AH Plus sealer in terms of flow, setting time and radiopacity

Guillain-Barre Syndrome: A Retrospective Study of Clinical and Epidemiological Features in Kurdistan, West of Iran, From 2005 To 2014

Background and aims: The most common cause of acute flaccid paralysis of all ages is Guillain-Barre syndrome (GBS). Further understanding of this disease is important because of its life-threatening nature in life. The aim of this study was to conduct a 10-year survey on epidemiological and clinical features of GBS in Tohid and Besat hospitals, Sanandaj, Iran, from 2005 to 2014. Methods: This study was a retrospective study, based on medical records, in which 98 hospitalized cases in Tohid and Besat hospitals (tertiary referral hospitals), Sanandaj, Iran, between 2005 and 2014 were investigated. The epidemiological and clinical information was obtained from eligible cases. Data analysis was performed using SPSS version 16. Chi-square and t test were used for analyses. The significant level was considered at P<0.05. Results: The mean age of cases with GBS was 22.16 years. Among final 69 patients who were studied, 36 cases (52.2%) were male and 33 cases (47.8%) were female. Most cases of disease occurred in the spring. Thirty-nine patients (56.52%) had risk factors like history of gastrointestinal infections, respiratory infections, and surgery 2-4 weeks before the disease onset. Four cases (10.25%) needed mechanical ventilation. The most common protocol of treatment was IVIg (n=47, 68%). More than half of the patients (52.2%) achieved relative recovery. In 6 patients, (8.7%) relapse was occurred. Conclusion: Our study showed that there was a significant relationship between sensory- motor involvement, gender and age. Moreover, the relationship between gender and prognosis was indicated (P<0.05)