30,067 research outputs found

    Supersymmetric Yang-Mills and Supergravity Amplitudes at One Loop

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    By applying the known expressions for SYM and SUGRA tree amplitudes, we write generating functions for the NNMHV box coefficients of SYM as well as the MHV, NMHV, and NNMHV box coefficients for SUGRA. The all-multiplicity generating functions utilize covariant, on-shell superspace whereby the contribution from arbitrary external states in the supermultiplet can be extracted by Grassmann operators. In support of the relation between dual Wilson loops and SYM scattering amplitudes at weak coupling, the SYM amplitudes are presented in a manifestly dual superconformal form. We introduce ordered box coefficients for calculating SUGRA quadruple cuts and prove that ordered coefficients generate physical cut amplitudes after summing over permutations of the external legs. The ordered box coefficients are produced by sewing ordered subamplitudes, previously used in applying on-shell recursion relations at tree level. We describe our verification of the results against the literature, and a formula for extracting the contributions from external gluons or gravitons to NNMHV superamplitudes is presented.Comment: 46 pages, 2 figures, additional references and clarifications include

    Intestinal absorption of radioiodide in rats exposed to hypoxia /380 mm Hg/ and food deprivation

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    Intestinal absorption of radioiodide in rats exposed to hypoxia and food deprivatio

    Cation-pi interactions in aromatics of biological and medicinal interest: Electrostatic potential surfaces as a useful qualitative guide

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    The cation-pi interaction is an important, general force for molecular recognition in biological receptors. Through the sidechains of aromatic amino acids, novel binding sites for cationic ligands such as acetylcholine can be constructed. We report here a number of calculations on prototypical cation-pi systems, emphasizing structures of relevance to biological receptors and prototypical heterocycles of the type often of importance in medicinal chemistry. Trends in the data can be rationalized using a relatively simple model that emphasizes the electrostatic component of the cation-pi interaction. In particular, plots of the electrostatic potential surfaces of the relevant aromatics provide useful guidelines for predicting cation-pi interactions in new systems

    Injury in Ireland

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    Injury mortality is the fourth commonest cause of death in Ireland. The treatment of injuries has a major impact on our hospitals and on our budget for health. Long term disability following accidents is a serious problem. The aim of this report is to examine the impact of accidents and injuries on the Irish population by analysing routine mortality and morbidity data, and to identify in turn those areas where preventive measures could have an impact. In Section One the literature review details the advantages and disadvantages of each type of routine data source used in this report. The interpretation of data should take account of the constraints of the available data collected. The usefulness of routine data collection is highlighted, while identifying areas for improvement. In Section Two the methodology employed in the study is detailed. In Section Three data on hospital admissions over a five-year period 1993-1997 are presented. An overview of injury admissions is presented, followed by further analysis of injury data by both cause and by age group. In Section Four data on all accident-related deaths over a 17-year period, 1980-1996, are presented, with overall mortality data and mortality data by age group and by major causes of injury death detailed. In Section Five comparisons are made between the eight health board regions for rates of admissions and deaths due to injury. In presenting the data we use a matrix format devised and recommended by the International Collaborative Effort on Injury Statistics to display injury simultaneously by cause and intent. The use of a common format will also facilitate regional and international comparisons. In Section Six the priority recommendations for injury prevention are outlined. The key findings are then discussed and further recommendations are presented with the aim of injury prevention, reduction of disability and improvement in injury surveillance

    A uvbyCaHbeta Analysis of the Old Open Cluster, NGC 6819

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    NGC 6819 is a richly populated, older open cluster situated within the Kepler field. A CCD survey of the cluster on the uvbyCaHbeta system, coupled with proper-motion membership, has been used to isolate 382 highly probable, single-star unevolved main-sequence members over a 20-arcminute field centered on the cluster. From 278 F dwarfs with high precision photometry in all indices, a mean reddening of E(b-y) = 0.117 +/- 0.005 or E(B-V) = 0.160 +/- 0.007 is derived, where the standard errors of the mean include both internal errors and the photometric zero-point uncertainty. With the reddening fixed, the metallicity derived from the same 278 stars is [Fe/H] = -0.116 +/- 0.101 from m_1 and -0.055 +/- 0.033 from hk, for a weighted average of [Fe/H] = -0.06 +/- 0.04, where the quoted standard errors of the mean values include the internal errors from the photometric scatter plus the uncertainty in the photometric zero points. If metallicity is derived using individual reddening values for each star to account for potential reddening variation across the face of the cluster, the analogous result is unchanged. The cluster members at the turnoff of the color-magnitude diagram are used to test and confirm the recently discovered variation in reddening across the face of the cluster, with a probable range in the variation of Delta[E(B-V)] = 0.045 +/-0.015. With the slightly higher reddening and lower [Fe/H] compared to commonly adopted values, isochrone fitting leads to an age of 2.3 +/- 0.2 Gyr for an apparent modulus of (m-M) = 12.40 +/-0.12.Comment: WIYN Open Cluster Study LXI; accepted to Astronomical Journal. 11 figures, 2 table

    Expression and Circular Dichroism Studies of the Extracellular Domain of the alpha Subunit of the Nicotinic Acetylcholine Receptor

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    To provide material suitable for structural studies of the nicotinic acetylcholine receptor, we have expressed and purified the NH2-terminal extracellular domain of the mouse muscle alpha subunit. Several constructs were initially investigated using Xenopus oocytes as a convenient small scale expression system. A fusion protein (alpha210GPI) consisting of the 210 NH2-terminal amino acids of the alpha subunit and a glycosylphosphatidylinositol anchorage sequence conferred surface alpha-bungarotoxin binding in oocytes. Coexpression of alpha210GPI with an analogous construct made from the delta subunit showed no evidence of heterodimer formation. The alpha210GPI protein was chosen for large scale expression in transfected Chinese hamster ovary cells. The alpha210GPI protein was cleaved from these cells and purified on an immunoaffinity column. Gel and column chromatography show that the purified protein is processed as expected and exists as a monomer. The purified protein also retains the two distinct, conformation-specific binding sites expected for the correctly folded alpha subunit. Circular dichroism studies of alpha210GPI suggest that this region of the receptor includes considerable beta-sheet secondary structure, with a small proportion of alpha-helix
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