Stability of oligosaccharides derived from lactulose during the processing of milk and apple juice

The scientific evidence on the bioactivity of oligosaccharides from lactulose has encouraged us to study their physicochemical modifications during the processing of milk and apple juice. The carbohydrate fraction with a degree of polymerization ≥3 was stable in milk heated at temperatures up to 100°C for 30 min and in apple juice heated up to 90°C for 15 min. An assessment of the Maillard reaction in heated milk pointed out a higher formation of furosine in milk with oligosaccharides from lactulose as compared to its counterpart without this ingredient, due to a higher presence of galactose. The organoleptic properties of juice with oligosaccharides from lactulose were acceptable and similar to those of apple juice with commercial galactooligosaccharides. The results presented herein demonstrate that oligosaccharides from lactulose can be used as prebiotic ingredients in a wide range of functional foods, including those intended for diabetics and lactose intolerant individuals.This work has been supported by project AGL2011-27884 from Spanish Ministerio de Economía y Competitividad.Peer Reviewe

Efficient GRASP+VND and GRASP+VNS metaheuristics for the traveling repairman problem

The traveling repairman problem is a customer-centric routing problem, in which the total waiting time of the customers is minimized, rather than the total travel time of a vehicle. To date, research on this problem has focused on exact algorithms and approximation methods. This paper presents the first metaheuristic approach for the traveling repairman problem

Datalog-Based program analysis with BES and RWL

This paper describes two techniques for Datalog query evaluation and their application to object-oriented program analysis. The first technique transforms Datalog programs into an implicit Boolean Equation System (Bes) that can then be solved by using linear-time complexity algorithms that are available in existing, general purpose verification toolboxes such as Cadp. In order to improve scalability and to enable analyses involving advanced meta-programming features, we develop a second methodology that transforms Datalog programs into rewriting logic (Rwl) theories. This method takes advantage of the preeminent features and facilities that are available within the high-performance system Maude, which provides a very efficient implementation of Rwl. We provide evidence of the practicality of both approaches by reporting on some experiments with a number of real-world Datalog-based analyses. © 2011 Springer-Verlag.This work has been partially supported by the eu(feder), the Spanish mec/micinn under grants tin2007-68093-C02 and tin2010-21062-C02-02, and the Generalitat Valenciana under grant Emergentes gv/2009/024. M.A.Feliu was partially supported by the Spanish mec fpu grant AP2008-00608.Alpuente Frasnedo, M.; Feliú Gabaldón, MA.; Joubert, C.; Villanueva García, A. (2011). Datalog-Based program analysis with BES and RWL. En Datalog Reloaded. Springer Verlag (Germany). 6702:1-20. https://doi.org/10.1007/978-3-642-24206-9_1S1206702Afrati, F.N., Ullman, J.D.: Optimizing joins in a map-reduce environment. In: Manolescu, I., Spaccapietra, S., Teubner, J., Kitsuregawa, M., Léger, A., Naumann, F., Ailamaki, A., Özcan, F. (eds.) EDBT. ACM International Conference Proceeding Series, vol. 426, pp. 99–110. ACM, New York (2010)Alpuente, M., Feliú, M., Joubert, C., Villanueva, A.: Defining Datalog in Rewriting Logic. Technical Report DSIC-II/07/09, DSIC, Universidad Politécnica de Valencia (2009)Alpuente, M., Feliú, M., Joubert, C., Villanueva, A.: Using Datalog and Boolean Equation Systems for Program Analysis. In: Cofer, D., Fantechi, A. (eds.) FMICS 2008. LNCS, vol. 5596, pp. 215–231. Springer, Heidelberg (2009)Alpuente, M., Feliú, M.A., Joubert, C., Villanueva, A.: Defining datalog in rewriting logic. In: De Schreye, D. (ed.) LOPSTR 2009. LNCS, vol. 6037, pp. 188–204. Springer, Heidelberg (2010)Andersen, H.R.: Model checking and boolean graphs. Theoretical Computer Science 126(1), 3–30 (1994)Bancilhon, F., Maier, D., Sagiv, Y., Ullman, J.D.: Magic Sets and Other Strange Ways to Implement Logic Programs. In: Proc. 5th ACM SIGACT-SIGMOD Symp. on Principles of Database Systems, PODS 1986, pp. 1–15. ACM Press, New York (1986)Ceri, S., Gottlob, G., Tanca, L.: Logic Programming and Databases. Springer, Heidelberg (1990)Chen, T., Ploeger, B., van de Pol, J., Willemse, T.A.C.: Equivalence Checking for Infinite Systems Using Parameterized Boolean Equation Systems. In: Caires, L., Vasconcelos, V.T. (eds.) CONCUR 2007. LNCS, vol. 4703, pp. 120–135. Springer, Heidelberg (2007)Clavel, M., Durán, F., Ejer, S., Lincoln, P., Martí-Oliet, N., Meseguer, J., Talcott, C.: All About Maude - A High-Performance Logical Framework. LNCS, vol. 4350. Springer, Heidelberg (2007)Dam, A., Ploeger, B., Willemse, T.: Instantiation for Parameterised Boolean Equation Systems. In: Fitzgerald, J.S., Haxthausen, A.E., Yenigun, H. (eds.) ICTAC 2008. LNCS, vol. 5160, pp. 440–454. Springer, Heidelberg (2008)de Moor, O., Sereni, D., Verbaere, M., Hajiyev, E., Avgustinov, P., Ekman, T., Ongkingco, N., Tibble, J.: QL: Object-oriented queries made easy. In: Lämmel, R., Visser, J., Saraiva, J. (eds.) GTTSE 2008. LNCS, vol. 5235, pp. 78–133. Springer, Heidelberg (2008)Feliú, M., Joubert, C., Tarín, F.: Efficient BES-based Bottom-Up Evaluation of Datalog Programs. In: Gulías, V., Silva, J., Villanueva, A. (eds.) Proc. X Jornadas sobre Programación y Lenguajes (PROLE 2010), Garceta, pp. 165–176 (2010)Feliú, M., Joubert, C., Tarín, F.: Evaluation strategies for datalog-based points-to analysis. In: Bendisposto, J., Leuschel, M., Roggenbach, M. (eds.) Proc. 10th Workshop on Automated Verification of Critical Systems (AVoCS 2010), pp. 88–103. Technical Report of Düsseldorf University (2010)Garavel, H., Mateescu, R., Lang, F., Serwe, W.: CADP 2006: A Toolbox for the Construction and Analysis of Distributed Processes. In: Damm, W., Hermanns, H. (eds.) CAV 2007. LNCS, vol. 4590, pp. 158–163. Springer, Heidelberg (2007)Hajiyev, E., Verbaere, M., de Moor, O.: CodeQuest: Scalable Source Code Queries with Datalog. In: Hu, Q. (ed.) ECOOP 2006. LNCS, vol. 4067, pp. 2–27. Springer, Heidelberg (2006)Hanus, M.: The Integration of Functions into Logic Programming: From Theory to Practice. Journal on Logic Programming 19 & 20, 583–628 (1994)Joubert, C., Mateescu, R.: Distributed On-the-Fly Model Checking and Test Case Generation. In: Valmari, A. (ed.) SPIN 2006. LNCS, vol. 3925, pp. 126–145. Springer, Heidelberg (2006)Leeuwen, J. (ed.): Formal Models and Semantics, vol. B. Elsevier, The MIT Press (1990)Liu, X., Smolka, S.A.: Simple Linear-Time Algorithms for Minimal Fixed Points. In: Larsen, K.G., Skyum, S., Winskel, G. (eds.) ICALP 1998. LNCS, vol. 1443, pp. 53–66. Springer, Heidelberg (1998)Liu, Y.A., Stoller, S.D.: From datalog rules to efficient programs with time and space guarantees. ACM Trans. Program. Lang. Syst. 31(6) (2009)Livshits, B., Whaley, J., Lam, M.: Reflection Analysis for Java. In: Yi, K. (ed.) APLAS 2005. LNCS, vol. 3780, pp. 139–160. Springer, Heidelberg (2005)Marchiori, M.: Logic Programs as Term Rewriting Systems. In: Rodríguez-Artalejo, M., Levi, G. (eds.) ALP 1994. LNCS, vol. 850, pp. 223–241. Springer, Heidelberg (1994)Mateescu, R.: Local Model-Checking of an Alternation-Free Value-Based Modal Mu-Calculus. In: Proc. 2nd Int’l Workshop on Verication, Model Checking and Abstract Interpretation, VMCAI 1998 (1998)Mateescu, R., Thivolle, D.: A Model Checking Language for Concurrent Value-Passing Systems. In: Cuellar, J., Sere, K. (eds.) FM 2008. LNCS, vol. 5014, pp. 148–164. Springer, Heidelberg (2008)Meseguer, J.: Conditional Rewriting Logic as a Unified Model of Concurrency. Theoretical Computer Science 96(1), 73–155 (1992)Meseguer, J.: Membership algebra as a logical framework for equational specification. In: Parisi-Presicce, F. (ed.) WADT 1997. LNCS, vol. 1376, pp. 18–61. Springer, Heidelberg (1998)Reddy, U.: Transformation of Logic Programs into Functional Programs. In: Proc. Symposium on Logic Programming (SLP 1984), pp. 187–197. IEEE Computer Society Press, Los Alamitos (1984)Reps, T.W.: Solving Demand Versions of Interprocedural Analysis Problems. In: Adsul, B. (ed.) CC 1994. LNCS, vol. 786, pp. 389–403. Springer, Heidelberg (1994)Rosu, G., Havelund, K.: Rewriting-Based Techniques for Runtime Verification. Autom. Softw. Eng. 12(2), 151–197 (2005)Schneider-Kamp, P., Giesl, J., Serebrenik, A., Thiemann, R.: Automated Termination Analysis for Logic Programs by Term Rewriting. In: Puebla, G. (ed.) LOPSTR 2006. LNCS, vol. 4407, pp. 177–193. Springer, Heidelberg (2007)Ullman, J.D.: Principles of Database and Knowledge-Base Systems, Volume I and II, The New Technologies. Computer Science Press, Rockville (1989)Vieille, L.: Recursive Axioms in Deductive Databases: The Query/Subquery Approach. In: Proc. 1st Int’l Conf. on Expert Database Systems, EDS 1986, pp. 253–267 (1986)Whaley, J.: Joeq: a Virtual Machine and Compiler Infrastructure. In: Proc. Workshop on Interpreters, Virtual Machines and Emulators, IVME 2003, pp. 58–66. ACM Press, New York (2003)Whaley, J., Avots, D., Carbin, M., Lam, M.S.: Using Datalog with Binary Decision Diagrams for Program Analysis. In: Yi, K. (ed.) APLAS 2005. LNCS, vol. 3780, pp. 97–118. Springer, Heidelberg (2005)Zheng, X., Rugina, R.: Demand-driven alias analysis for C. In: Proc. 35th ACM SIGPLAN-SIGACT Symp. on Principles of Programming Languages, POPL 2008, pp. 197–208. ACM Press, New York (2008

Strategic directions in constraint programming

An abstract is not available