62 research outputs found
Perfect Fluid Quantum Anisotropic Universe: Merits and Challenges
The present paper deals with quantization of perfect fluid anisotropic
cosmological models. Bianchi type V and IX models are discussed following
Schutz's method of expressing fluid velocities in terms of six potentials. The
wave functions are found for several examples of equations of state. In one
case a complete wave packet could be formed analytically. The initial
singularity of a zero proper volume can be avoided in this case, but it is
plagued by the usual problem of non-unitarity of anisotropic quantum
cosmological models. It is seen that a particular operator ordering alleviates
this problem.Comment: 13 pages, 4 figures; Accepted for publication in Gen Relativ Gravi
Mast cell concentration and skin wound contraction in rats treated with Brazilian pepper essential oil (Schinus terebinthifolius Raddi)
Schinus terebinthifolius Raddi ( Aroeira) leaves oil attenuates inflammatory responses in cutaneous wound healing in mice
Immunostaining with D2–40 improves evaluation of lymphovascular invasion, but may not predict sentinel lymph node status in early breast cancer
<p>Abstract</p> <p>Background</p> <p>Sentinel lymph node (SLN) biopsy is a widely used diagnostic procedure in the management of early breast cancer. When SLN is free of metastasis, complete axillary dissection may be skipped for staging in clinically N0 patients, allowing a more conservative procedure. Histological tumor features that could reliably predict SLN status have not yet been established. Since the degree of tumor lymphangiogenesis and vascularization may theoretically be related to the risk of lymph node metastasis, we sought to evaluate the relationship between lymph vessel invasion (LVI), lymphatic microvascular density (LVD), microvascular density (MVD) and VEGF-A expression, with SLN status and other known adverse clinical risk factors.</p> <p>Methods</p> <p>Protein expression of D2–40, CD34, and VEGF-A was assessed by immunohistochemistry on paraffin-embedded sections of primary breast cancer specimens from 92 patients submitted to SLN investigation. The presence of LVI, the highest number of micro vessels stained for D2–40 and CD34, and the protein expression of VEGF-A were compared to SLN status, clinicopathological features and risk groups.</p> <p>Results</p> <p>LVI was detected in higher ratios by immunostaining with D2–40 (p < 0.0001), what would have changed the risk category from low to intermediate in four cases (4.3%). There was no association between LVI and other angiogenic parameters determined by immunohistochemistry with SLN macrometastases, clinical features or risk categories.</p> <p>Conclusion</p> <p>Assessment of LVI in breast carcinoma may be significantly increased by immunostaining with D2–40, but the clinical relevance of altering the risk category using this parameter may not be advocated according to our results, neither can the use of LVI and LVD as predictors of SLN macrometastasis in early breast cancer.</p
Tradução e adaptação transcultural da Multiple Sclerosis Walking Scale - 12 (MSWS-12) para a lÃngua portuguesa do Brasil
Consumo de suplementos por jovens freqüentadores de academias de ginástica em São Paulo
Fatores associados ao uso de benzodiazepÃnicos no serviço municipal de saúde da cidade de Coronel Fabriciano, Minas Gerais, Brasil
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