MEDPREPARATY, PRIMENIMYYe PRI OSTROM OTRAVLENII UGARNYM GAZOM V SHAKHTAKH. ZAMENITELI PLAZMY KROVI. GOLUBAYA KROV' [MEDICATIONS WHICH CAN BE USED IN CASE OF CARBON MONOXIDE ACUTE POISONING IN THE MINES. BLOOD PLASMA SUBSTITUTES. BLUE BLOOD]

Fires in the operational underground mine openings, as a rule, are catastrophic and lead to numerous victims. Due to the transfer of combustion products by the ventilation stream of the mine ventilation, they can be spread over long distances from the fire site and mortally injure miners along the course of the air stream. Essential assistance to miners in such emergency situations is provided by means of individual protection of miners, which are breathing apparatus of various types - so-called self-rescuers. There are cases anyway when they cannot protect from poisonous combustion products action. Then in the arsenal of mine rescuers there must be medical preparations capable of restoring the respiratory functions of the miners the fire victims. The purpose of this article is to familiarize mining specialists and VGSCh workers with the current state of medical preparations for carbon monoxide effect neutralization

МЕДПРЕПАРАТЫ, ПРИМЕНИМЫЕ ПРИ ОСТРОМ ОТРАВЛЕНИИ УГАРНЫМ ГАЗОМ В ШАХТАХ. ЗАМЕНИТЕЛИ ПЛАЗМЫ КРОВИ. ГОЛУБАЯ КРОВЬ

Fires in the operational underground mine openings, as a rule, are catastrophic and lead to numerous victims. Due to the transfer of combustion products by the ventilation stream of the mine ventilation, they can be spread over long distances from the fire site and mortally injure miners along the course of the air stream. Essential assistance to miners in such emergency situations is provided by means of individual protection of miners, which are breathing apparatus of various types - so-called self-rescuers. There are cases anyway when they cannot protect from poisonous combustion products action. Then in the arsenal of mine rescuers there must be medical preparations capable of restoring the respiratory functions of the miners the fire victims. The purpose of this article is to familiarize mining specialists and VGSCh workers with the current state of medical preparations for carbon monoxide effect neutralization.Пожары в действующих горных выработках шахт, как правило, носят катастрофический характер и приводят к многочисленным жертвам. За счёт переноса продуктов горения вентиляционной струёй проветривания шахты они -продукты горения- могут распространиться на большие расстояния от очага пожара и смертельно травмировать шахтёров по ходу воздушной струи. Существенную помощь шахтёрам в таких аварийных ситуациях оказывают средства индивидуальной защиты шахтёров, представляющие собой различного рода дыхательные аппараты, так называемые самоспасатели. Но бывают случаи, когда они не могут защитить от действия ядовитых продуктов горения. Тогда на вооружении горноспасателей должны находиться медицинские препараты, способные восстановить дыхательные функции пострадавших при пожаре шахтеров. Целью данной статьи служит ознакомление горных специалистов и работников ВГСЧ с современным состоянием медицинских препаратов для нейтрализации действия угарных газов

The ability of choline derivatives synthesized by multi-component reactions in the inhibition of ache enzyme

Multi-component reactions (MCRs) are strong synthetic tools in which more than two starting materials are coupled together with a purpose to form the multi-functionalized compounds in a one-pot process. In this procedure, they used an additional step without changing the solvent, the so-called sequential-addition procedure, to limit the number of synthetic steps while increasing the complexity and the molecular diversity, which are highly step-economical reactions. The Ugi reaction, one of the most common multi-component reactions, has recently fascinated chemists with the high diversity brought by its four-or three-component-based isonitrile. The Ugi reaction has been introduced in organic synthesis as a novel, efficient and useful tool for the preparation of libraries of multifunctional peptides, natural products, and heterocyclic compounds with stereochemistry control. © 2021, Dr. Yashwant Research Labs Pvt. Ltd.. All rights reserved

Thermostabilization System Based on Two-phase Closed Cryogenic Thermosyphon for RED100 Detector

AbstractThe RED 100 emission detector requires thermostabilization at about 100K. The heat transfer characteristics of a two-phase closed cryogenic thermosyphon made of copper pipe and bellow flex hoses with nitrogen fluid have been investigated. The thermosyphon consists of sealed pipe enclosed in a vacuum jacket and uses a free-boiling liquid nitrogen pool as a cooling machine. The system is very flexible and can provide heat transfer rate up to 100W in the temperature range of 80-100K

Searching for active mobile genetic elements in dsRNA fraction of Pinus sylvestris having witches broom abnormalities

The most common type of coniferous mobile genetic elements are retrotransposons. Despite of their early positive impact on evolution of modern coniferous species they can have a significant negative impact for Forestry and breeding. Breaking genomic structural integrity mobile elements can cause phenotypic defects of plants. In this regard, the study of the diversity of coniferous mobile genetic elements is particularly interesting. In the present paper, we describe mobile genetic elements in dsRNA fraction of Pinus sylvestris having witches broom abnormalities. In result of assembled contigs analysis by RepeatMasker 70 mobile genetic elements were identified. A 68 of that were retroelements. Most of elements represented by Gypsy (16 contigs) and Copia (48 contigs). In 4 cases retroelements specific to Pinus taeda were identified. In most cases fragments of integrase (24), reverse transcriptase (22) and RNaseH (15) were identified. Results of the study may be of interest for coniferous breeding and genetic specialists. The raw data of these experiments have been deposited at NCBI under the accession number SAMN06185845