Raised cortisol excretion rate in urine and contamination by topical steroids

No abstract available

Subcentimeter depth resolution using a single-photon counting time-of-flight laser ranging system at 1550 nm wavelength

We demonstrate subcentimeter depth profiling at a stand off distance of 330m using a time-of-flight approach based on time-correlated single-photon counting. For the first time to our knowledge, the photon-counting time-of-flight technique was demonstrated at a wavelength of 1550nm using a superconducting nanowire single-photon detector. The performance achieved suggests that a system using superconducting detectors has the potential for low-light-level and eye-safe operation. The system’s instrumental response was 70ps full width at half-maximum, which meant that 1cm surface-to-surface resolution could be achieved by locating the centroids of each return signal. A depth resolution of 4mm was achieved by employing an optimized signal-processing algorithm based on a reversible jump Markov chain Monte Carlo method

Acute changes in the systemic inflammatory response are associated with transient decreases in circulating 25-hydroxyvitamin D concentrations following elective knee arthroplasty [POSTER]

No abstract available

Mesoscopic modelling of bipolar charge evolution in CN-PPV LEDs

Since various chances are possible in the molecular structure of the repeat unit, substituted poly(para-phenylenevinylene) (PPV) has ben used as active component in light-emitting diodes (LEDs) to obtain light emission in a wide range of colours.A major aspect determining device performance is the competition between current flow, trapping and recombination within the polymer layer. By suitable Monte Carlo calculations, we have performed computer experiments in which bipolar charge carriers are injected at constant rate in polymer networks made of cyano-substituted PPV chains with variable length and orientation. The intra-molecular electronic properties used in these simulations were calculated by a quantum molecular dynamics method. In order to assess the influence of cyano-substitution on the properties of single-layer PPV LEDs, we have focused our attention on bipolar charge evolution in time. Specifically addressed are the differences in electric field strength needed for intra-molecular charge mobility of electrons and holes and their consequences at mesoscopic scale. (C) 2004 Elsevier B.V. All rights reserved

Spin resonance of 2D electrons in a large-area silicon MOSFET

We report electron spin resonance (ESR) measurements on a large-area silicon MOSFET. An ESR signal at g-factor 1.9999(1), and with a linewidth of 0.6 G, is observed and found to arise from two-dimensional (2D) electrons at the Si/SiO2 interface. The signal and its intensity show a pronounced dependence on applied gate voltage. At gate voltages below the threshold of the MOSFET, the signal is from weakly confined, isolated electrons as evidenced by the Curie-like temperature dependence of its intensity. The situation above threshold appears more complicated. These large-area MOSFETs provide the capability to controllably tune from insulating to conducting regimes by adjusting the gate voltage while monitoring the state of the 2D electron spins spectroscopically.Comment: 7 pages, 3 figures, submitted to Physica E special edition for EPS2DS-1

Acute changes in the systemic inflammatory response are associated with transient decreases in circulating 25-hydroxyvitamin D concentrations following elective knee arthroplasty [POSTER]

No abstract available

Compression and intelligence: social environments and communication

Compression has been advocated as one of the principles which pervades inductive inference and prediction - and, from there, it has also been recurrent in definitions and tests of intelligence. However, this connection is less explicit in new approaches to intelligence. In this paper, we advocate that the notion of compression can appear again in definitions and tests of intelligence through the concepts of `mind-reading¿ and `communication¿ in the context of multi-agent systems and social environments. Our main position is that two-part Minimum Message Length (MML) compression is not only more natural and effective for agents with limited resources, but it is also much more appropriate for agents in (co-operative) social environments than one-part compression schemes - particularly those using a posterior-weighted mixture of all available models following Solomonoff¿s theory of prediction. We think that the realisation of these differences is important to avoid a naive view of `intelligence as compression¿ in favour of a better understanding of how, why and where (one-part or two-part, lossless or lossy) compression is needed.We thank the anonymous reviewers for their helpful comments, and we thank Kurt Kleiner for some challenging and ultimately very helpful questions in the broad area of this work. We also acknowledge the funding from the Spanish MEC and MICINN for projects TIN2009-06078-E/TIN, Consolider-Ingenio CSD2007-00022 and TIN2010-21062-C02, and Generalitat Valenciana for Prometeo/2008/051.Dowe, DL.; Hernández Orallo, J.; Das, PK. (2011). Compression and intelligence: social environments and communication. En Artificial General Intelligence. Springer Verlag (Germany). 6830:204-211. https://doi.org/10.1007/978-3-642-22887-2_21S2042116830Chaitin, G.J.: Godel’s theorem and information. International Journal of Theoretical Physics 21(12), 941–954 (1982)Dowe, D.L.: Foreword re C. S. Wallace. Computer Journal 51(5), 523–560 (2008); Christopher Stewart WALLACE (1933-2004) memorial special issueDowe, D.L.: Minimum Message Length and statistically consistent invariant (objective?) Bayesian probabilistic inference - from (medical) “evidence”. Social Epistemology 22(4), 433–460 (2008)Dowe, D.L.: MML, hybrid Bayesian network graphical models, statistical consistency, invariance and uniqueness. In: Bandyopadhyay, P.S., Forster, M.R. (eds.) Handbook of the Philosophy of Science. Philosophy of Statistics, vol. 7, pp. 901–982. Elsevier, Amsterdam (2011)Dowe, D.L., Hajek, A.R.: A computational extension to the Turing Test. Technical Report #97/322, Dept Computer Science, Monash University, Melbourne, Australia, 9 pp (1997)Dowe, D.L., Hajek, A.R.: A non-behavioural, computational extension to the Turing Test. In: Intl. Conf. on Computational Intelligence & multimedia applications (ICCIMA 1998), Gippsland, Australia, pp. 101–106 (February 1998)Hernández-Orallo, J.: Beyond the Turing Test. J. Logic, Language & Information 9(4), 447–466 (2000)Hernández-Orallo, J.: Constructive reinforcement learning. International Journal of Intelligent Systems 15(3), 241–264 (2000)Hernández-Orallo, J.: On the computational measurement of intelligence factors. In: Meystel, A. (ed.) Performance metrics for intelligent systems workshop, pp. 1–8. National Institute of Standards and Technology, Gaithersburg, MD, U.S.A (2000)Hernández-Orallo, J., Dowe, D.L.: Measuring universal intelligence: Towards an anytime intelligence test. Artificial Intelligence 174(18), 1508–1539 (2010)Hernández-Orallo, J., Minaya-Collado, N.: A formal definition of intelligence based on an intensional variant of Kolmogorov complexity. In: Proc. Intl Symposium of Engineering of Intelligent Systems (EIS 1998), pp. 146–163. ICSC Press (1998)Legg, S., Hutter, M.: Universal intelligence: A definition of machine intelligence. Minds and Machines 17(4), 391–444 (2007)Lewis, D.K., Shelby-Richardson, J.: Scriven on human unpredictability. Philosophical Studies: An International Journal for Philosophy in the Analytic Tradition 17(5), 69–74 (1966)Oppy, G., Dowe, D.L.: The Turing Test. In: Zalta, E.N. (ed.) Stanford Encyclopedia of Philosophy, Stanford University, Stanford (2011), http://plato.stanford.edu/entries/turing-test/Salomon, D., Motta, G., Bryant, D.C.O.N.: Handbook of data compression. Springer-Verlag New York Inc., Heidelberg (2009)Sanghi, P., Dowe, D.L.: A computer program capable of passing I.Q. tests. In: 4th International Conference on Cognitive Science (and 7th Australasian Society for Cognitive Science Conference), vol. 2, pp. 570–575. Univ. of NSW, Sydney, Australia (July 2003)Sayood, K.: Introduction to data compression. Morgan Kaufmann, San Francisco (2006)Scriven, M.: An essential unpredictability in human behavior. In: Wolman, B.B., Nagel, E. (eds.) Scientific Psychology: Principles and Approaches, pp. 411–425. Basic Books (Perseus Books), New York (1965)Searle, J.R.: Minds, brains and programs. Behavioural and Brain Sciences 3, 417–457 (1980)Solomonoff, R.J.: A formal theory of inductive inference. Part I. Information and control 7(1), 1–22 (1964)Sutton, R.S.: Generalization in reinforcement learning: Successful examples using sparse coarse coding. Advances in neural information processing systems, 1038–1044 (1996)Sutton, R.S., Barto, A.G.: Reinforcement learning: An introduction. The MIT Press, Cambridge (1998)Turing, A.M.: Computing machinery and intelligence. Mind 59, 433–460 (1950)Veness, J., Ng, K.S., Hutter, M., Silver, D.: A Monte Carlo AIXI Approximation. Journal of Artificial Intelligence Research, JAIR 40, 95–142 (2011)Wallace, C.S.: Statistical and Inductive Inference by Minimum Message Length. Springer, Heidelberg (2005)Wallace, C.S., Boulton, D.M.: An information measure for classification. Computer Journal 11(2), 185–194 (1968)Wallace, C.S., Dowe, D.L.: Intrinsic classification by MML - the Snob program. In: Proc. 7th Australian Joint Conf. on Artificial Intelligence, pp. 37–44. World Scientific, Singapore (November 1994)Wallace, C.S., Dowe, D.L.: Minimum message length and Kolmogorov complexity. Computer Journal 42(4), 270–283 (1999); Special issue on Kolmogorov complexityWallace, C.S., Dowe, D.L.: MML clustering of multi-state, Poisson, von Mises circular and Gaussian distributions. Statistics and Computing 10, 73–83 (2000

An evolutionarily-unique heterodimeric voltage-gated cation channel found in aphids

We describe the identification in aphids of a unique heterodimeric voltage-gated sodium channel which has an atypical ion selectivity filter and, unusually for insect channels, is highly insensitive to tetrodotoxin. We demonstrate that this channel has most likely arisen by adaptation (gene fission or duplication) of an invertebrate ancestral mono(hetero)meric channel. This is the only identifiable voltage-gated sodium channel homologue in the aphid genome(s), and the channel’s novel selectivity filter motif (DENS instead of the usual DEKA found in other eukaryotes) may result in a loss of sodium selectivity, as indicated experimentally in mutagenised Drosophila channels

Statistics of Atmospheric Correlations

For a large class of quantum systems the statistical properties of their spectrum show remarkable agreement with random matrix predictions. Recent advances show that the scope of random matrix theory is much wider. In this work, we show that the random matrix approach can be beneficially applied to a completely different classical domain, namely, to the empirical correlation matrices obtained from the analysis of the basic atmospheric parameters that characterise the state of atmosphere. We show that the spectrum of atmospheric correlation matrices satisfy the random matrix prescription. In particular, the eigenmodes of the atmospheric empirical correlation matrices that have physical significance are marked by deviations from the eigenvector distribution.Comment: 8 pages, 9 figs, revtex; To appear in Phys. Rev.