1,729 research outputs found
Propellant tank pressurization system Patent
Method and apparatus for pressurizing propellant tanks used in propulsion motor feed syste
Is a Once Daily Topical Application of Fixed-Dose Combination Gel Containing Adapalene 0.1%-Benzoyl Peroxide (BPO) 2.5%(Adapalene-BPO) Effective at Treating Mild to Moderate Acne?
OBJECTIVE: The objective of this selective EBM review is to determine whether or not a once daily topical application of fixed-dose combination gel containing adapalene 0.1%-benzoyl peroxide (BPO) 2.5% (adapalene-BPO) is effective at treating mild to moderate acne.
STUDY DESIGN: Three multi-center double blind randomized control studies published in the English language between 2007-2013.
STUDY SOURCES: Three peer-reviewed RCTS were found using Pubmed. These studies compared the same fixed-dose combination gel adapalene-BPO against placebo vehicles. Two studies also compared to additional groups receiving monotherapies.
OUTCOMES MEASURED: Outcomes measured were improvement of participant’s acne according to the Investigator’s Global Assessment of Acne Severity (IGS), percentage change in acne lesions from baseline to post treatment, safety and tolerability assessment scales, participants’ assessment of their acne improvement, and Children’s Dermatology Life Quality Index.
RESULTS: The fixed-dose combination gel of adapalene-BPO demonstrated significant differences with total lesion counts and treatment efficacy. It was significantly more effective than monotherapies or a placebo vehicle for the treatment of mild to moderate acne. Adverse events were similar to those experienced with the monotherapies and mainly consisted of dryness and erythema that primarily occurred early in the studies.
CONCLUSIONS: A once daily topical application of adapalene-BPO is effective at treating mild to moderate acne. Adapalene-BPO demonstrated superior efficacy, increased lesion count reduction, and a faster onset of action compared to monotherapies consisting of adapalene or benzoyl peroxide as well as a placebo vehicle
Data Access for LIGO on the OSG
During 2015 and 2016, the Laser Interferometer Gravitational-Wave Observatory
(LIGO) conducted a three-month observing campaign. These observations delivered
the first direct detection of gravitational waves from binary black hole
mergers. To search for these signals, the LIGO Scientific Collaboration uses
the PyCBC search pipeline. To deliver science results in a timely manner, LIGO
collaborated with the Open Science Grid (OSG) to distribute the required
computation across a series of dedicated, opportunistic, and allocated
resources. To deliver the petabytes necessary for such a large-scale
computation, our team deployed a distributed data access infrastructure based
on the XRootD server suite and the CernVM File System (CVMFS). This data access
strategy grew from simply accessing remote storage to a POSIX-based interface
underpinned by distributed, secure caches across the OSG.Comment: 6 pages, 3 figures, submitted to PEARC1
An Apparatus to Control and Monitor the Para-D2 Concentration in a Solid Deuterium, Superthermal Source of Ultra-cold Neutrons
Controlling and measuring the concentration of para-D2 is an essential step
toward realizing solid deuterium as an intense ultra-cold neutron (UCN) source.
To this end, we implemented an experimental technique to convert para- to
ortho-deuterium molecules by flowing D2 gas through a cryogenic cell filled
with paramagnetic hydrous ferric oxide granules. This process efficiently
reduced the para-D2 concentration from 33.3% to 1.5%. Rotational Raman
spectroscopy was applied to measure the residual para-D2 contamination to
better than 2 parts in 10^3, and the hydrogen contamination to 1 part in 10^3.
We also contrast our optical technique to conventional thermal conductivity
measurements of the para-D2 concentration, reporting some of the relevant
strengths and weaknesses of our implementation of each technique.Comment: accepted for publication in NIM
Hydrogen slush density reference system
A hydrogen slush density reference system was designed for calibration of field-type instruments and/or transfer standards. The device is based on the buoyancy principle of Archimedes. The solids are weighed in a low-mass container so arranged that solids and container are buoyed by triple-point liquid hydrogen during the weighing process. Several types of hydrogen slush density transducers were developed and tested for possible use as transfer standards. The most successful transducers found were those which depend on change in dielectric constant, after which the Clausius-Mossotti function is used to relate dielectric constant and density
Instrumentation for hydrogen slush storage containers
Hydrogen liquid and slush tank continuous inventory during ground storag
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A New Method for the Analysis of Human Hair : A Morphological Case Study of Five Sample Populations
Hair is an important piece of evidence in forensic and archaeological investigations. Analysis of the morphological features of hair has been reported since at least the early 1800's. However, many questions still remain unanswered such as, how can human groups (or local populations) be analyzed and possibly distinguished from each other based on the morphology of their hair? This investigation successfully established a set of procedures for analysis of human hair morphology and explored the possibility of separating populations by examining a case study of 40 hairs from five sample populations (Mongolian, English, Vietnamese, Native American Sioux and Oneida). The methodology leads the investigator from the point of receiving a single hair to acquiring a list of specific, discernible traits characterizing that hair. These methods included a variety laboratory procedures (cleaning, casting, mounting and microtome sectioning of the hair) and examination procedures (microscope and computer imaging and developing a key and database). Statistical analysis was then utilized in order to determine the variability and/or relationships between the populations. Although the results were not statistically significant, they weakly support a division of three groups: English, Mongolian and Vietnamese, and Sioux and Oneida. The small sample size and overlap between the five populations is a limiting factor in attempting to discriminate between populations and should be taken into consideration in future investigations
Novel Nonreciprocal Acoustic Effects in Antiferromagnets
The possible occurrence of nonreciprocal acoustic effects in antiferromagnets
in the absence of an external magnetic field is investigated using both (i) a
microscopic formulation of the magnetoelastic interaction between spins and
phonons and (ii) symmetry arguments. We predict for certain antiferromagnets
the existence of two new nonreciprocal (non-time invariant) effects:
A boundary-condition induced nonreciprocal effect and the occurrence of
transversal phonon modes propagating in opposite directions having different
velocities. Estimates are given and possible materials for these effects to be
observed are suggested.Comment: Euro. Phys. Lett. (in press
FlashCam: A fully digital camera for CTA telescopes
The future Cherenkov Telescope Array (CTA) will consist of several tens of
telescopes of different mirror sizes. CTA will provide next generation
sensitivity to very high energy photons from few tens of GeV to >100 TeV.
Several focal plane instrumentation options are currently being evaluated
inside the CTA consortium. In this paper, the current status of the FlashCam
prototyping project is described. FlashCam is based on a fully digital camera
readout concept and features a clean separation between photon detector plane
and signal digitization/triggering electronics.Comment: In Proceedings of the 2012 Heidelberg Symposium on High Energy
Gamma-Ray Astronomy. All CTA contributions at arXiv:1211.184
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