Pharmacotherapy exacerbations of chronic inflammatory conditions of female genital sphere using to Gepon and Longidaza

Research objective was establishment of changes of the metabolic status at an aggravation chronic salpingoophoritis and detection of efficiency of use in "Gepon's" complex pharmacotherapy and "Longidaza's" various medicinal form

The Results of Paleoanthropological Analysis of the Remains of a Warrior from an Elite Burial of the XIV Century near the City of Krymsk

The work contains the results of a comprehensive archaeological and paleoanthropological analysis of unique materials which were received at the beginning of the 20th century by the Kuban Museum (now the Krasnodar Territory Krasnodar State Historical and Archaeological Museum-Reserve named after E.D. Felitsyn): fragments of the upholstery of a copper coffin, bronze parts of a saber sheath, iron arrowheads, a wooden comb, and an almost complete skeleton of a buried young man 25-35 years. This miraculously preserved collection comes from a predatory excavation of an underground military entombment next to the modern city of Krymsk. The grave goods, and the closest analogies to the finds and features of the burial rite, undoubtedly indicate the elite nature of the burial and allow us to date the complex to the second half of the 14th century. The analysis using the principal component method showed us a high similarity of the buried skull with materials which were found in the burials of the Aushedz, Karras and Glebovka entombments. This can indicate that the skull belonged to the sedentary population of the North-Western Caucasus – the direct ancestors of the modern Circassians or Abazas. The marks left by arrowheads on the vertebrae and the inside of the rib let us suggest that these injuries were the cause of the warrior’s death

Radial HI Profiles at the Periphery of Galactic Disks: The Role of Ionizing Background Radiation

Observations of neutral hydrogen in spiral galaxies reveal a sharp cutoff in the radial density profile at some distance from the center. Using 22 galaxies with known HI distributions as an example, we discuss the question of whether this effect can be associated exclusively with external ionizing radiation, as is commonly assumed. We show that before the surface density reaches $\sigma_{\textrm{HI}}\le 0.5 {\cal M}_\odot/{\textrm {pc}}^2$(the same for galaxies of different types), it is hard to expect the gas to be fully ionized by background radiation. For two of 13 galaxies with a sharp drop in the HI profile, the "steepening" can actually be caused by ionization. At the same time, for the remaining galaxies, the observed cutoff in the radial HI profile is closer to the center than if it was a consequence of ionization by background radiation and, therefore, it should be caused by other factors.Comment: 15 pages, 6 figure

The chiral Anomalous Hall effect in re-entrant AuFe alloys

The Hall effect has been studied in a series of AuFe samples in the re-entrant concentration range, as well as in part of the spin glass range. An anomalous Hall contribution linked to the tilting of the local spins can be identified, confirming theoretical predictions of a novel topological Hall term induced when chirality is present. This effect can be understood in terms of Aharonov-Bohm-like intrinsic current loops arising from successive scatterings by canted local spins. The experimental measurements indicate that the chiral signal persists, meaning scattering within the nanoscopic loops remains coherent, up to temperatures of the order of 150 K.Comment: 7 pages, 11 eps figures Published version. Minor change

Conductivity, weak ferromagnetism and charge instability in α−MnS\alpha-MnS single crystal

The temperature dependence of resistivity, magnetization and electron-spin resonance of the $\alpha- MnS$ single crystal were measured in temperature range of $5 K < T < 550 K$. Magnetization hysteresis in applied magnetic field up to 0.7 T at $T=5 K, 77 K, 300 K$, irreversible temperature behavior of magnetization and resistivity were found . The obtained data were explained in terms of degenerate tight binding model using random phase approximation. The contribution of holes in $t_{2g}$ and $e_g$ bands of manganese ions to the conductivity, optical absorbtion spectra and charge instability in $\alpha -MnS$ were studied. Charge susceptibility maxima resulted from the competition of the on-site Coulomb interaction between the holes in different orbitals and small hybridization of sub-bands were calculated at $T=160 K, 250 K, 475 K$.Comment: 6 pages, 12 figure

Sensor impedimétrico para la detección de bacterias patogénicas mediante péptidos antimicrobianos

Áccesit Congreso SIBB 2015La peri-implantitis, una inflamación causada por la formación del biofilm, es una de las causas más importantes de la fallida de los implantes en odontología. Por esto, la detección de bacterias patogénicas al inicio del proceso de formación de biofilms, representa una estrategia muy potente para la prevención de las infecciones en los implantes. Entre los diferentes métodos para la detección de bacterias patogénicas, los biosensores electroquímicos, especialmente los sistemas basados en impedancia (EIS), presentan una serie de ventajas como la miniaturización, la mejora en sensibilidad y el bajo coste. En este sentido, los péptidos antimicrobianos (AMPs), conocidos como componentes del sistema inmune y con actividad hacia las bacterias, pueden ser usados para desarrollar elementos de bioreconocimiento altamente efectivos. Por lo tanto, el objetivo de este estudio es la combinación del uso de EIS y la habilidad de los AMPs para obtener biosensores con alta sensibilidad, especificidad y límites de detección muy bajos para la detección de bacterias patogénicas.Peer ReviewedAward-winnin

Insilico test of functional role of rs8068318 polymorphism of arterial hypertension-associated TBX2 candidate gene

In the course of this study, the functional role of rs8068318 polymorphism of the TBX2 candidate gene associated with the development of arterial hypertension was studied. The selection of the polymorphic locus was based on the data of the catalog of genome-wide association study (GWAS) of the National Human Genome Research Institute. The functional role was evaluated using online software: HaploReg (v4.1), GTExportal, and PolyPhen-

Перспективы внедрения цифрового рубля в денежный оборот России: атрибуты и принципы формирования доверенной цифровой среды

The rapid nature of the modernization of monetary turnover, accompanied by geopolitical risks against the background of post-pandemic economic recovery and the regionalization process, no longer just arouses the discursive interest of society, but becomes an indispensable condition of the new reality. The process of money turnover transformation by introducing digital currencies into circulation in the wave of digitalization among world powers lagging behind the evolving environment of the cryptocurrency industry is developing into a process of formalization of metaverses and penetrates deeper into the socio-economic reality. The problem of the Russian practice of developing the payment environment consists in its catching-up character, caused by the spontaneous formation of the digital society, resulting in the expansion of the scope of alternative finance outside the legal field. The purpose of the paper is to determine the inherent attributes of the digital trusted environment necessary to ensure digital ruble turnover, based on an empirical study of society’s perceptions about the prospects for using the digital form of the national monetary unit by representatives of various generations. We used systematization, grouping, comparative and content analysis, surveys, and the quota method to achieve the paper’s purpose. The survey involved 35,327 residents from different regions. As a result, the authors revealed the low level of readiness of society for the introduction of the digital ruble as a substitute for cash and cryptocurrency. The paper focuses on the need for an integrated approach to the disclosure of the digital ruble’s value and benefits, which contributes to its successful launch and promotion in the market. The results of the research highlight the importance of correspondence in the digital ruble category “digital currencies”, and also the impossibility of making incorrect decisions in the transformation of money turnover, which leads to the growth of risks of digital inequality, the clash of interests of certain groups of the population in the prevailing behavioral patterns in the form of a cautious attitude to digital finance with insufficient financial literacy.Стремительный характер модернизации денежного оборота, сопровождаемой геополитическими рисками на фоне постпандемийного восстановления экономики и процесса регионализации, не просто вызывает дискурсивный интерес общества, а становится неотъемлемым условием новой реальности. Процесс трансформации денежного оборота путем внедрения цифровых валют на волне гонки цифровизации среди мировых держав, отстающих от эволюционирующей криптовалютной индустрии, перерастает в процесс формализации метавселенных и все глубже проникает в социально- экономическую действительность. Проблема российской практики развития платежной среды заключается в ее догоняющем характере, обусловленном самопроизвольным становлением цифрового общества, приводящем к расширению масштабов альтернативных финансов вне рамок правового поля. Целью исследования стало определение неотъемлемых атрибутов доверенной цифровой среды, необходимой для обеспечения оборота цифрового рубля, и выявление особенностей восприятия перспектив использования цифровой формы национальной денежной единицы представителями различных поколений. Для достижения цели использованы методы систематизации, группировки, компаративного и кон- тент-анализа, анкетирования, метод квот. В опросе приняли участие 35 327 жителей различных регионов страны. Выявлен низкий уровень готовности общества к внедрению цифрового рубля как заместителя наличных денег и альтернативы криптовалюты. Акцентировано внимание на необходимости комплексного подхода к раскрытию ценности и преимуществ цифрового рубля, содействующего его успешному запуску и продвижению. Результаты исследования подчеркивают значимость соответствия цифрового рубля категории «цифровые валюты» и акцентируют внимание на недопустимости принятия неверных решений при трансформации денежного оборота, приводящих к нарастанию рисков цифрового неравенства, столкновению интересов определенных групп населения в условиях сложившихся поведенческих паттернов в виде настороженного отношения к Digital finance при недостаточной финансовой грамотности

The role of polymorphism of hereditary thrombophilia candidate genes in the development of arterial hypertension in women with preeclampsia

Preeclampsia is a severe pregnancy complication that has long been one of the leading causes of maternal and perinatal mortality and morbidity worldwide. Despite the achievements of modern medicine, the etiology of this pathology is not known. Multiple risk factors for the development of PE have been identified: arterial hypertension, diabetes mellitus, obesity, a hereditary history of preeclampsia, thrombophilia, etc., but recently, special attention has been paid to genetic determinants, namely, the contribution of individual polymorphic loci of various gene

Plasticity of an extra-strong nanocrystalline stainless steel controlled by the "dislocation-segregation'' interaction

We study three structurally different states of nanocrystalline 316 steel and show that the state, where boundaries containing excess concentration of alloying elements are combined with mobile dislocations in grain interiors, allows maintaining extraordinarily high strength and remarkably enhanced plasticity. Underlying mechanisms featuring interaction between the segregations and mobile dislocations are discussed