The Simplest Model of the Turning Movement of a Car with its Possible Sideslip

The simplest model of the turning movement of a car with its possiple sideslip is considered. To this end, a nonholonomic problem with nonretaining constraints is solved. The four possible types of the car motion are studied

Case of Hemorrhagic Vasculitis with Difficult Stream of 9 Years Old Boy

We are presenting a case of hemorrhagic vasculitis with difficult stream of 9 years old boy. Feature of this case is manifestation of the disease after quinsy with pronounced lymphoproliferative syndrome (enlargement of anterior and posterior cervical and submandibular lymph nodes up to 12-15 mm in diameter), which made it necessary to conduct a differential diagnosis with lymphoproliferative disorders. Thereby the biopsy of lymph node was made. Another feature was that with hemorrhagic rash on lower extremities extensive necrosis were developed, accompanied by severe pain and no analgesic effect. Later joined abdominal and renal syndromes, with development of cruel nephritis. The therapy allowed to achieve clinical remission, however the urinary syndrome retained for long. After correction of the therapy (sandimmun) there were marked rapid positive changes

TIMELY DETECTION OF PULMONARY TUBERCULOSIS AND INFLUENCING FACTORS

This study presents analysis of the timely detection of pulmonary tuberculosis in 1334 patients who underwent treatment in the Regional TB Dispensary N1 in Krasnoyarsk city in 2010-2011. Late detection of tuberculosis was established in 60,2 %, and factors which are contributing to it were as following: the male, living in rural areas, social vulnerability, and. violation of the regulated terms of X-ray examination. The significance of late diagnosed patients to increase the reservoir of tuberculosis infection and spread of drug-resistant strains among the population was shown. It was determined that an increase in coverage of population by preventive X-ray examinations resulted in improvement of quality indicators only in 2,6 % of active detection of pulmonary tuberculosis in the form of growing proportion of the patients revealed during preventive examinations timely, as well as reducing proportion of fibro-cavernous pulmonary tuberculosis and. post-mortem diagnosis of tuberculosis among the newly diagnosed patients. During the active detection of TB among population with a focus of work on real, established during the research, its groups the conclusion about the need to use the obtained results was made

SYNTHESIS AND PHOTOPHYSICAL PROPERTIES OF 2-ARYL-4-(4-CYANOPHENYL)QUINAZOLINES

This work was supported by the Russian Scientific Foundation (project 22-23-00006)

3-ARYL-[1,2,4]TRIAZOLO[4,3-c]QUINAZOLINE DERIVATIVES: SYNTHESIS AND MODIFICATIONS

This work was supported by the Ministry of Science and Higher Education of Russian Federation, State Contract no FEUZ-2020-0058 (Н687.42Б.223/20)

SYNTHESIS OF (2-ARYLQUINAZOLIN-4-YL)HYDRAZONES OF 2-HYDROXYBENZALDEHYDES AS POTENTIAL PHOSPHOINOSITIDE 3-KINASE (IP3Kδ) AND CASEIN KINASE 2 (CK2) INHIBITORS

This work was supported by the Ministry of Science and Higher Education of Russian Federation, State Contract no FEUZ-2020-0058 (Н687.42Б.223/20)

The complex approach to the geochemical research of oil and organic substance with the purpose of planning of geological exploration work for oil and gas

The article is devoted to the first results obtained for the complex of geochemical studies of the crude oils and organic matter of Vyngayakhinskoye field rocks of the West-Siberian oil and gas province. The main objective of this paper is the determination of the genetic unity of or, on the contrary, in the difference of the crude oil produced at the field, dedicated to the various oil complexes. Authors investigated the correlation between organic matter the breeds and crude oils of various oil-and-gas complexes with a view to identifying areas of generation, directions, and the scope and stages of migration of hydrocarbons. The study, in the future, can be used in the development of recommendations for the planning of geological exploration works on oil and gas, as well as to develop the reserves already discovered oil and gas deposits

The Case of Dilated Cardiomiopathy, the Girl of Three Years from the Silver-Rassel Syndrom

Dilated cardiomyopathy is a serious disabling disease with unclear etiology. In some cases, its occurrence is associated with genetic mutations. In this context the case of dilated cardiomyopathy of the three years old girl from the Silver-Russell syndrome is of considerable interest. This is a genetic disorder characterized by numerous anomalies in the symmetry of the body, malnutrition and premature puberty

Workplace Violence among Female Sex Workers Who Use Drugs in Vancouver, Canada: Does Client Targeted Policing Increase Safety?

Workplace violence, by clients or predators, poses serious negative health consequences for sex workers. In 2013, the Vancouver (British Columbia), Canada Police Department changed their guidelines with the goal of increasing safety for sex workers by focusing law enforcement on clients and third parties, but not sex workers. We sought to examine the trends and correlates of workplace violence among female sex workers (FSW) before and after the guideline change, using data collected from prospective cohorts of persons who use illicit drugs in Vancouver, Canada. Among 259 FSW, 21.0% reported workplace violence at least once during the study period between 2008 and 2014. There was no statistically significant change in rates of workplace violence after the guideline change. In our multivariable analysis, daily heroin use was independently associated with workplace violence. The 2013 policing guideline change did not appear to have resulted in decreased reports of workplace violence. Increased access to opioid agonist therapies may reduce workplace violence among drug-using FSW