84 research outputs found
The integral monodromy of hyperelliptic and trielliptic curves
We compute the \integ/\ell and \integ_\ell monodromy of every irreducible
component of the moduli spaces of hyperelliptic and trielliptic curves. In
particular, we provide a proof that the \integ/\ell monodromy of the moduli
space of hyperelliptic curves of genus is the symplectic group
\sp_{2g}(\integ/\ell). We prove that the \integ/\ell monodromy of the
moduli space of trielliptic curves with signature is the special
unitary group \su_{(r,s)}(\integ/\ell\tensor\integ[\zeta_3])
Bishop and Laplacian Comparison Theorems on Three Dimensional Contact Subriemannian Manifolds with Symmetry
We prove a Bishop volume comparison theorem and a Laplacian comparison theorem for three dimensional contact subriemannian manifolds with symmetry
Critical slope p-adic L-functions of CM modular forms
For ordinary modular forms, there are two constructions of a p-adic
L-function attached to the non-unit root of the Hecke polynomial, which are
conjectured but not known to coincide. We prove this conjecture for modular
forms of CM type, by calculating the the critical-slope L-function arising from
Kato's Euler system and comparing this with results of Bellaiche on the
critical-slope L-function defined using overconvergent modular symbols.Comment: 14 page
Comparative study of non-invasive force and stress inference methods in tissue
In the course of animal development, the shape of tissue emerges in part from
mechanical and biochemical interactions between cells. Measuring stress in
tissue is essential for studying morphogenesis and its physical constraints.
Experimental measurements of stress reported thus far have been invasive,
indirect, or local. One theoretical approach is force inference from cell
shapes and connectivity, which is non-invasive, can provide a space-time map of
stress and relies on prefactors. Here, to validate force- inference methods, we
performed a comparative study of them. Three force-inference methods, which
differ in their approach of treating indefiniteness in an inverse problem
between cell shapes and forces, were tested by using two artificial and two
experimental data sets. Our results using different datasets consistently
indicate that our Bayesian force inference, by which cell-junction tensions and
cell pressures are simultaneously estimated, performs best in terms of accuracy
and robustness. Moreover, by measuring the stress anisotropy and relaxation, we
cross-validated the force inference and the global annular ablation of tissue,
each of which relies on different prefactors. A practical choice of
force-inference methods in distinct systems of interest is discussed.Comment: 12 pages, 8 figures, EPJ E: Topical issue on "Physical constraints on
morphogenesis and evolution
Unified quantitative characterization of epithelial tissue development.
Understanding the mechanisms regulating development requires a quantitative characterization of cell divisions, rearrangements, cell size and shape changes, and apoptoses. We developed a multiscale formalism that relates the characterizations of each cell process to tissue growth and morphogenesis. Having validated the formalism on computer simulations, we quantified separately all morphogenetic events in the Drosophila dorsal thorax and wing pupal epithelia to obtain comprehensive statistical maps linking cell and tissue scale dynamics. While globally cell shape changes, rearrangements and divisions all significantly participate in tissue morphogenesis, locally, their relative participations display major variations in space and time. By blocking division we analyzed the impact of division on rearrangements, cell shape changes and tissue morphogenesis. Finally, by combining the formalism with mechanical stress measurement, we evidenced unexpected interplays between patterns of tissue elongation, cell division and stress. Our formalism provides a novel and rigorous approach to uncover mechanisms governing tissue development
Versatile Synthesis of Small NLO‐Active Molecules Forming Amorphous Materials with Spontaneous Second‐Order NLO Response
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