3,561 research outputs found
Three-dimensional flows in slowly-varying planar geometries
We consider laminar flow in channels constrained geometrically to remain
between two parallel planes; this geometry is typical of microchannels obtained
with a single step by current microfabrication techniques. For pressure-driven
Stokes flow in this geometry and assuming that the channel dimensions change
slowly in the streamwise direction, we show that the velocity component
perpendicular to the constraint plane cannot be zero unless the channel has
both constant curvature and constant cross-sectional width. This result implies
that it is, in principle, possible to design "planar mixers", i.e. passive
mixers for channels that are constrained to lie in a flat layer using only
streamwise variations of their in-plane dimensions. Numerical results are
presented for the case of a channel with sinusoidally varying width
Precision Drift Chambers for the Atlas Muon Spectrometer
ATLAS is a detector under construction to explore the physics at the Large
Hadron Collider at CERN. It has a muon spectrometer with an excellent momentum
resolution of 3-10%, provided by three layers of precision monitored-drift-tube
chambers in a toroidal magnetic field. A single drift tube measures a track
point with a mean resolution close to 100 micron, even at the expected high
neutron and gamma background rates. The tubes are positioned within the chamber
with an accuracy of 20 microns, achieved by elaborate construction and assembly
monitoring procedures.Comment: 3 pages, 2 eps figures, Proceedings for poster at Physics in
Collisions Conference (PIC03), Zeuthen, Germany, June 2003. FRAP1
Magnetic Response of Magnetospirillum Gryphiswaldense
In this study we modelled and measured the U-turn trajectories of individual
magnetotactic bacteria under the application of rotating magnetic fields,
ranging in ampitude from 1 to 12 mT. The model is based on the balance between
rotational drag and magnetic torque. For accurate verification of this model,
bacteria were observed inside 5 m tall microfluidic channels, so that they
remained in focus during the entire trajectory. From the analysis of hundreds
of trajectories and accurate measurements of bacteria and magnetosome chain
dimensions, we confirmed that the model is correct within measurement error.
The resulting average rate of rotation of Magnetospirillum Gryphiswaldense is
0.74 +- 0.03 rad/mTs.Comment: 17 pages, 12 figure
Large-Scale Production of Monitored Drift Tube Chambers for the ATLAS Muon Spectrometer
Precision drift tube chambers with a sense wire positioning accuracy of
better than 20 microns are under construction for the ATLAS muon spectrometer.
70% of the 88 large chambers for the outermost layer of the central part of the
spectrometer have been assembled. Measurements during chamber construction of
the positions of the sense wires and of the sensors for the optical alignment
monitoring system demonstrate that the requirements for the mechanical
precision of the chambers are fulfilled
The role of the mobile proton in fucose migration
Fucose migration reactions represent a substantial challenge in the analysis of fucosylated glycan structures by mass spectrometry. In addition to the well-established observation of transposed fucose residues in glycan-dissociation product ions, recent experiments show that the rearrangement can also occur in intact glycan ions. These results suggest a low-energy barrier for migration of the fucose residue and broaden the relevance of fucose migration to include other types of mass spectrometry experiments, including ion mobility-mass spectrometry and ion spectroscopy. In this work, we utilize cold-ion infrared spectroscopy to provide further insight into glycan scrambling in intact glycan ions. Our results show that the mobility of the proton is a prerequisite for the migration reaction. For the prototypical fucosylated glycans Lewis x and blood group antigen H-2, the formation of adduct ions or the addition of functional groups with variable proton affinity yields significant differences in the infrared spectra. These changes correlate well with the promotion or inhibition of fucose migration through the presence or absence of a mobile proton
Nanoliter-sized overheated reactor
We report on a microfluidic system formed by 200 nl water droplets, encapsulated by a 600 nl mineral oil placed on a hydrophobically coated glass microscope cover slip. The micromachined heater underneath the glass was able to heat up the sample at a heating rate of 650 °C/s, heating the water sample up to 200 °C in less than 2 s. The sample/glass and the sample/oil interface did not have nucleation centers, showing that the sample reached a superheated stage without the necessity of being pressurized to suppress boiling. This method can be utilized for various applications currently being conducted in autoclaves.Web of Science1062art. no. 02410
Performance of the ATLAS Precision Muon Chambers under LHC Operating Conditions
For the muon spectrometer of the ATLAS detector at the large hadron collider
(LHC), large drift chambers consisting of 6 to 8 layers of pressurized drift
tubes are used for precision tracking covering an active area of 5000 m2 in the
toroidal field of superconducting air core magnets. The chambers have to
provide a spatial resolution of 41 microns with Ar:CO2 (93:7) gas mixture at an
absolute pressure of 3 bar and gas gain of 2?104. The environment in which the
chambers will be operated is characterized by high neutron and background with
counting rates of up to 100 per square cm and second. The resolution and
efficiency of a chamber from the serial production for ATLAS has been
investigated in a 100 GeV muon beam at photon irradiation rates as expected
during LHC operation. A silicon strip detector telescope was used as external
reference in the beam. The spatial resolution of a chamber is degraded by 4 ?m
at the highest background rate. The detection efficiency of the drift tubes is
unchanged under irradiation. A tracking efficiency of 98% at the highest rates
has been demonstrated
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