Strong damping of phononic heat current by magnetic excitations in SrCu_2(BO_3)_2

Measurements of the thermal conductivity as a function of temperature and magnetic field in the 2D dimer spin system SrCu$_2$(BO$_3$)$_2$ are presented. In zero magnetic field the thermal conductivity along and perpendicular to the magnetic planes shows a pronounced double-peak structure as a function of temperature. The low-temperature maximum is drastically suppressed with increasing magnetic field. Our quantitative analysis reveals that the heat current is due to phonons and that the double-peak structure arises from pronounced resonant scattering of phonons by magnetic excitations.Comment: a bit more than 4 pages, 2 figures included; minor changes to improve the clarity of the presentatio

PREVALENCE AND CAUSES OF TRAUMATIC DENTAL INJURIES TO ANTERIOR TEETH AMONG PRIMARY SCHOOL CHILDREN IN SANA'A CITY, YEMEN

Objectives: The current study was conducted to reveal the prevalence and causes of traumatic dental injuries to permanent anterior teeth among mixed dentition of schoolchildren in Sana'a City, Yemen. Methods: A cross-sectional study was performed on 1252 schoolchildren aged 7-12 years in three districts of Sana'a city, Yemen. They numbered 700 males and 552 females from 26 randomly selected public and private schools. Clinical examination of permanent anterior teeth was done according to the classification of Ellis modified by Fried. Results: Prevalence of TDI was 10.30%, with a male ratio of 4.8: female 1, (P <0.05). Most of the children suffered only one damage to the tooth and most of them are in the maxillary central incisors. The TDI increased with older age (10-12 years old) (16.5%) with odds ratio 4.8, (p<0.05). Regarding the site of trauma, most injuries happened in males on the street (44.9%) while in females happened at home (31.81%) and falls were the main cause of TDI. In both sexes, the most common type of injury was class I (enamel fracture) followed by class II (enamel and dentine without pulp involvement). Conclusion: In conclusion, the prevalence of TDI in permanent anterior teeth among mixed dentition of school children in Sana’a was high, higher in males than in females, with a peak age of 10 to 12 years, falls was the common cause, and occurred mostly on the street for boys and home for females. Accordingly, educational programs should be developed that focus on ways to prevent dental trauma and the benefits of seeking urgent treatment to maintain avulsed and fractured teeth.                                 Peer Review History: Received 13 May 2020; Revised 15 June; Accepted 1 July, Available online 15 July 2020 Academic Editor: Dr. Asia Selman Abdullah, Al-Razi university, Department of Pharmacy, Yemen, [email protected] UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file:                Reviewer's Comments:  Average Peer review marks at initial stage: 6.0/10 Average Peer review marks at publication stage: 8.0/10 Reviewer(s) detail: Dr. Alfonso Alexander Aguileral, University of Veracruz,  Mexico, [email protected] Dr. Mohamed Awad Mousnad, Faculty of Pharmacy, International University of Africa (IUA), Khartoum, Sudan, [email protected]  Similar Articles: SERO-PREVALENCE OF HEPATITIS C VIRUS AMONG DENTAL CLINIC WORKERS IN SANA’A CITY- YEMEN AND THE RISK FACTORS CONTRIBUTING FOR ITS INFECTIO

Design of ultra-swollen lipidic mesophases for the crystallization of membrane proteins with large extracellular domains

In meso crystallization of membrane proteins from lipidic mesophases is central to protein structural biology but limited to membrane proteins with small extracellular domains (ECDs), comparable to the water channels (3-5 nm) of the mesophase. Here we present a strategy expanding the scope of in meso crystallization to membrane proteins with very large ECDs. We combine monoacylglycerols and phospholipids to design thermodynamically stable ultra-swollen bicontinuous cubic phases of double-gyroid (Ia3d), double-diamond (Pn3m), and double-primitive (Im3m) space groups, with water channels five times larger than traditional lipidic mesophases, and showing re-entrant behavior upon increasing hydration, of sequences Ia3d?Pn3m?Ia3d and Pn3m?Im3m?Pn3m, unknown in lipid self-assembly. We use these mesophases to crystallize membrane proteins with ECDs inaccessible to conventional in meso crystallization, demonstrating the methodology on the Gloeobacter ligand-gated ion channel (GLIC) protein, and show substantial modulation of packing, molecular contacts and activation state of the ensued proteins crystals, illuminating a general strategy in protein structural biology

PREVALENCE OF PREMATURE LOSS OF PRIMARY TEETH AT THE AGE OF 6-10 YEARS IN SANA'A CITY, YEMEN

Background and Objectives: Primary teeth and the integrity of the primary teeth are very important for the normal growth and progress of the occlusal relationships and the dentofacial structures. Premature loss of the primary teeth may lead to the loss of the arch length needed for the eruption of permanent teeth and thus lead to rotation, crowding, and impaction of permanent teeth. This study aimed to determine the prevalence of premature loss of primary teeth among children aged 6-10 years in Sana'a city, Yemen. Materials and methods: This observational cross-sectional study included 1091 children, aged 6-10 years. An experienced examiner the first author carried out all clinical examinations under natural light. Data were collected including age and missing teeth. Results: The results showed that 26% of the sample suffered premature loss of primary teeth with no significant difference between the sexes (P> 0.05). There was low  in prevalence of premature loss of primary teeth in 10 years (17.7%), while the rate raised to 29.7%, 31.6%, and 31.7% in 6,7 and 9 years respectively. When considering the number of teeth, the prevalence of one premature loss was 10.8%, followed by two premature losses (9.8%), while the loss rate of 3 or more was5.4%. Considering dental arch 61.8% of loss was Mandible loss, while the loss in Maxilla was 38.1% only. The most common missing tooth is the first lower right primary molar (17%). Conclusion: The prevalence of premature loss in our study is similar to that of developing countries, the rate was low at 10 years for children, while the rate increased at 6,7 and 9 years; most of the loss was in the lower jaw and the most common missing tooth was the right lower primary molar. This result determines the importance of increasing awareness of this problem and focusing on the need for more preventive efforts to maintain healthy and natural teeth that improve the chewing function and aesthetic appearance of children and the entire population.                         Peer Review History: Received 25 July 2020; Revised 15 August; Accepted 26 August, Available online 15 September 2020 Academic Editor: Dr. DANIYAN Oluwatoyin Michael, Obafemi Awolowo University, ILE-IFE, Nigeria, [email protected] UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file:                Reviewer's Comments: Average Peer review marks at initial stage: 6.5/10 Average Peer review marks at publication stage: 7.5/10 Reviewer(s) detail: Dr. Mohamed Amin El-Emam, Department of Pharmacology and Therapeutics, Faculty of Pharmacy and Drug Manufacturing, Pharos University in Alexandria (PUA), Alexandria, Egypt, [email protected] Dr. Mohammad Tauseef, College of Pharmacy, Chicago State University, [email protected] Similar Articles:  CAUSES FOR EXTRACTION OF PERMANENT TEETH IN GENERAL DENTAL PRACTICES IN YEMEN PREVALENCE AND CAUSES OF TRAUMATIC DENTAL INJURIES TO ANTERIOR TEETH AMONG PRIMARY SCHOOL CHILDREN IN SANA'A CITY, YEMEN PREVALENCE OF MALOCCLUSION AMONG YEMENI CHILDREN OF PRIMARY SCHOOLS RISK FACTORS OF PERIODONTAL DISEASES AMONG YEMENI YOUNG DENTAL PATIENT

PREVALENCE OF STAPHYLOCOCCUS AUREUS IN DENTAL INFECTIONS AND THE OCCURRENCE OF MRSA IN ISOLATES

Objectives:  Staphylococcus aureus is an opportunist that causes systemic infections and dental infections in the human being body. This organism increases its resistance to many categories of antibiotics all day and turn out to be more resistant, and this led to a growing feeling of concern in this era. Given this fact, the aims of this study were to determine the frequency of S. aureus in oral infections and to determine the prevalence of MRSA strains and the sensitivity of isolated S. aureus to antibiotics, in patients who attended dental clinics in major public hospitals and private clinics in the city of Sana'a-Yemen. Subjects and methods:  The study was conducted for a year, early in December 2018 and ending in November 2019. The study included 296 patients, 153 male and 143 female, ages 5 to 65, with an average age of 36.2 years. Demographic and clinical data were collected in questionnaire, then pus or oral swabs were collected from patients, cultivated, isolated and identified by standard laboratory techniques. MRSA was ascertained by means of the method of disc diffusion to 1µg of oxicillin disc and 5 µg of methacillin disc; an antimicrobial sensitivity test was carried out by disc diffusion method of selected antibiotics.The oral  infections include  dental abscesses,  periodontal abscesses, gingivitis, periodentitis, dental caries,  pulpitis and oral thrush. Results:  Of a total of 296 cultured pus and swabs, only 217 produced a positive culture (73.3%). Gram-positive bacteria formed 67.4% of the total isolates where S. aureus was the predominant pathogen (43.1%).  The prevalence of MRSA was 23.5%. There was a higher rate of antibiotic resistance tested in MRSA isolates compared to a lower rate of resistance in MSSA as well as 22.2% of MRSA isolates were vancomycin resistant, while only 11.4% of MSSA were vancomycin resistant. Conclusion:  It can be concluded, S. aureus was the most widespread isolate in dental infections, high rate of  MRSA,  the appearance of S. aureus isolates resistant to vancomycin and other broad choice of antibiotics have raised MRSA in oral infections into a multi-drug-resistant, making it more and more hazardous in oral infections. Consistent assessment of oral associated infections and observing the pattern of antibiotic sensitivity and strict drug policy for antibiotics are recommended.                        Peer Review History: Received 16 April 2020; Revised 2 May; Accepted 12 May, Available online 15 May 2020 Academic Editor:Ahmad Najib, Universitas Muslim Indonesia, Makassar, Indonesia, [email protected] UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file:                Reviewer's Comments: Average Peer review marks at initial stage: 5.5/10 Average Peer review marks at publication stage: 8.0/10 Reviewer(s) detail: Dr. Mohamed Awad Mousnad, Faculty of Pharmacy, International University of Africa (IUA), Khartoum, Sudan, [email protected] Dr. George Zhu, Tehran University of Medical Sciences, Tehran, Iran, [email protected] Similar Articles: PREVALENCE OF METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS (MRSA) AND ANTIMICROBIAL SUSCEPTIBILITY PATTERNS AT A PRIVATE HOSPITAL IN SANA'A, YEMEN PREVALENCE, ANTIMICROBIAL SUSCEPTIBILITY PATTERN AND RISK FACTORS OF MRSA ISOLATED FROM CLINICAL SPECIMENS AMONG MILITARY PATIENTS AT 48 MEDICAL COMPOUND IN SANA'A CITY-YEME

Surgical approach of large-sized hepatic tumors

Universitatea de Medicină “Gr.T.Popa”, Spitalul Universitar “Sf.Spiridon”, Iaşi, România, Al XII-lea Congres al Asociației Chirurgilor „Nicolae Anestiadi” din Republica Moldova cu participare internațională 23-25 septembrie 2015Introducere: Există încă numeroase controverse privind managementul tumorilor hepatice voluminoase. Scopul studiului este să evalueze retrospectiv efectele dimensiunii şi diferitelor tipuri de rezecție chirurgicală asupra evoluției postoperatorii precoce. Material şi metode: Pacienții înregistrați consecutiv în baza de date a Clinicii I Chirurgie în perioada 2000-2014 cu tumori hepatice primitive şi secundare au fost împărțiți în două grupuri în funcție de dimensiunea tumorii hepatice (grupul 1 – >10 cm şi grupul 2 – <10 cm) şi de tipul de procedură utilizată. Rezultate: Durata operației şi cantitatea de sânge pierdută intraoperator au fost semnificativ mai mari (p=0,01 şi, respectiv, p=0,03) pentru tumorile din grupul 1. Evoluția postoperatorie a fost similară pentru rezecții anatomice şi non-anatomice. Concluzii: Strategiile de management şi progresele tehnologice din ultima perioadă au îmbunătățit rezultatele tratamentului chirurgical pentru pacienții cu carcinom hepatocelular de mari dimensiuni.Introduction: Controversies still exist regarding the management of large-sized hepatic tumors. The aim of the study is to retrospectively evaluate the effects of the size and different types of surgical resection to the early postoperative outcome. Material and methods: Consecutive patients registered in our database from 2000 to 2014 with primitive or metastatic liver tumors were divided in 2 groups according to the size of the hepatic tumor (Group 1 – ≥10 cm and Group 2 – <10 cm) and the selected operative procedure used. Results: The operation time was significantly longer (p=0.01) and the amount of blood loss was significantly higher (p=0.03) in liver tumors ≥10 cm. Surgical outcome after anatomic or non-anatomic resection was similar. Conclusion: The recent management strategy and technological advances improved the results of surgical treatment for patients with large hepatocellular carcinoma

Informative EST-SSR markers for genotyping and intraspecific differentiation of Brassica oleracea var. capitata L.

Brassica oleraceae var. capitata L. is characterized by a high level of intraspecific heterogeneity due to some biological features that cause difficulties for breeding creating genetically homogenous forms and maintaining their genetic purity. Microsatellites (SSR) are highly polymorphic markers of plant genomes and represent one of the most effective tools for assessing genetic polymorphism. Among microsatellites, EST-SSR are most interesting, because they are directly linked to the expressed sequences and for that reason are widely used for analysis of genetic diversity and population structure. In this work, we studied the effectiveness of the use of transferable EST-SSR markers for both analyzing white cabbage diversity and genotyping pure lines. As a result, 15 microsatellite loci were characterized for the information content, allelic frequencies and heterogeneity levels. The effective multiallelic markers (Bo20TR, BoDCTD4, BoPC34, BoPLD1, BoCalc, BoPC15) with high information content (PIC &gt; 0.7) that could be successfully used for analysis of inter- and intravarietal polymorphism in B. oleracea var. capitata were identified. It has been shown that intervarietal polymorphism expressed as the allelic diversity of EST SSR loci greatly facilitates varietal identification and typing of individual plants for breeding purposes. Based on the SSR-evaluation and subsequent clustering, the genetic structure of the breeding collection was identified, which showed that most experimental forms, in spite of different origin, have a common ancestral genetic basis. The identified donors of rare alleles could potentially be a source of valuable genetic segregation for further B. oleracea breeding improvement

Autobiographical memory retrieval and appraisal in social anxiety disorder

The final publication is available at Elsevier via https://dx.doi.org/10.1016/j.brat.2018.06.008 © 2018. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/Individuals with social anxiety disorder (SADs; n = 41) and healthy controls (HCs; n = 40) were administered the Waterloo Images and Memories Interview, in which they described mental images that they tend to experience in both anxiety-provoking and non-anxiety-provoking social situations. Participants then recalled, in as much detail as possible, specific autobiographical memories of salient aversive and non-aversive social experiences that they believed led to the formation of these images. Audio-recorded memory narratives were transcribed and coded based on the procedure of the Autobiographical Interview, which provides a precise measure of the degree of episodic detail contained within each memory. Participants also rated the subjective properties of their recalled memories. Results revealed that participants across the two groups retrieved equivalent rates of both aversive and non-aversive social memories. However, SAD participants' memories of aversive events contained significantly more episodic detail than those of HCs, suggesting that they may be more highly accessible. Moreover, participants with SAD appraised their memories of aversive experiences as more distressing and intrusive than HCs, and perceived them as having a significantly greater influence on their self-perception. In contrast, no group differences were observed for memories of non-aversive events. Findings have the potential to shed new light on autobiographical memory in SAD, with implications for psychotherapeutic intervention.Canada Research Chairs ProgramSocial Sciences and Humanities Research Council of CanadaCanadian Institutes of Health Researc

ПРИМЕНЕНИЕ КЛЕТОЧНОЙ ИНЖЕНЕРИИ ДЛЯ СОЗДАНИЯ КОНСТАНТНОГО ИСХОДНОГО СЕЛЕКЦИОННОГО МАТЕРИАЛА КАПУСТЫ БЕЛОКОЧАННОЙ СОРТА НАДЗЕЯ И ЦМС ОБРАЗЦОВ

The anther derived androgenic plants of white head cabbage cv. Nadzeja and CMS samples were obtained. The cytological analysis of ploidy level of regenerated plants and doubled haploids obtained by treatment of meristems with colchicine was performed. On the basis of androgenic doubled hap loids of white head cabbage genotypes the seed plants were developed.Культивированием пыльников получены андрогенные растения капусты белокочанной сорта Надзея и ЦМС образцов. Проведен цитологический анализ плоидности регенерантов и удвоенных гаплоидов на их основе, полученных колхицинированием пазушных меристем. На основе андрогенных удвоенных гаплоидов капусты белокочанной изучавшихся генотипов выращены семенные растения

ВКЛАД МОЛЕКУЛЯРНО-ГЕНЕТИЧЕСКОЙ ДИВЕРГЕНЦИИ КАПУСТЫ БЕЛОКОЧАННОЙ В РЕАЛИЗАЦИЮ ПРОДУКТИВНОГО ПОТЕНЦИАЛА ГИБРИДОВ F1

The prediction efficiency of white cabbage F1 hybrid performance based on ISSR and RAPD markers was carried out. In result molecular-genetics evaluation of white cabbage collection, five divergent lines were selected and tested by full diallel (5×5) mating design. Through analysis relationship genetic divergence of parental lines and F1 hybrid performance the significant correlations (r &gt; 0.5) were found for the main yield components. Yield potential of half-diallel F1 hybrids was predetermined total GD by 67.2 % (R = r2), whereas no significant associations were found for reciprocal F1. Consequently, heterotic response does not simply result from the overall genetic diversity within a hybrid, but is likely only diversity at some specific loci causing the formation of superior F1 genotype with high expression of the traits.Проведено изучение эффективности предсказания продуктивного потенциала гибридов F1 капусты белокочанной на основе оценки генетической дивергенции исходных форм, величину которой рассчитывали с использованием ISSR- и RAPD-маркеров. В результате молекулярно-генетического исследования селекционной коллекции отобрали 5 линий, которые прошли испытание в системе полного диаллельного скрещивания. Гибриды F1 в большинстве комбинаций достоверно превосходили родителей по основным хозяйственно ценным признакам. Анализ сопряженности дивергенции родительских форм с компонентами урожая F1 показал, что существуют достоверные корреляции (r &gt; 0,5) между уровнем GD и основными компонентами продуктивности. При этом продуктивный потенциал прямых гибридов F1 на 67,2 % (R = r2) предопределен общей GD родительских форм, тогда как для реципрокных F1 статистически значимых связей не обнаружено. Вероятно, формирование высокопродуктивного гетерозисного генотипа не настолько связано с общей гетерогенностью гибридного генома, как с полиморфизмом в отдельных специфических локусах, которые обусловливают высокую экспрессию признаков в F1