Open data and smallholder food and nutritional security

This report was commissioned CTA as a member of the GODAN initiative. It aims to provide a better understanding of the actual impact of the open data movement on the food and nutrition security of smallholders and highlight the areas of potential unfilled opportunity

Moxalactam Therapy for Obstetric and Gynecologic Infections

Moxalactam, a new cephalosporin antibiotic with a broad spectrum of activity, was evaluated for safety and therapeutic efficacy in the treatment of genital tract infections in women. Fifty-three patients with postpartum endometritis or acute or chronic pelvic inflammatory disease were treated with 2 g of moxalactam iv every 8 hr, usually for five days or longer. Appropriate cultures of peripheral blood, endometrium, cul-de-sac aspirates, urine, wound, and endocervix (only for Neisseria gonorrhoeae) were performed. Overall, 90.6% (48 of 53) of the patients were successfully treated with moxalactam - 86.2% (25 of 29) and 95.8% (23 of 24) of the patients with endometritis and pelvic inflammatory disease, respectively. Therapy failed in one of five bacteremic patients with endometritis. Of all the bacteria isolated from appropriate culture sites, 58% (224 of 383) were anaerobes, with anaerobic gram-negative rods - particularly Bacteroides bivius-and gram-positive cocci being predominant. Of 206 anaerobic strains tested with moxalactam by agar dilution techniques, 82% (169 of 206) were susceptible (minimal inhibitory concentration [MIC], ⩽8 μg/ml), 11.6% (24 of 206) were moderately susceptible (MIC, 16-32 μg/ml), and 6.3% (13 of 206) were resistant (MIC, ⩾64 μg/ml). Among the aerobic isolates, enterococci were uniformly resistant. Thus, moxalactam performed well as a single agent in this open clinical trail for women with infections of the genital trac

Kinetics of Surfactant Adsorption at Fluid/Fluid Interfaces: Non-ionic Surfactants

We present a model treating the kinetics of adsorption of soluble surface-active molecules at the interface between an aqueous solution and another fluid phase. The model accounts for both the diffusive transport inside the solution and the kinetics taking place at the interface using a free-energy formulation. In addition, it offers a general method of calculating dynamic surface tensions. Non-ionic surfactants are shown, in general, to undergo a diffusion-limited adsorption, in accord with experimental findings.Comment: 6 pages, 3 figures, see also cond-mat/960814

Automated assembly inspection using a multiscale algorithm trained on synthetic images

Includes bibliographical references.An important part of a robust automated assembly process is an accurate and efficient method for the inspection of finished assemblies. This paper presents a novel multiscale assembly inspection algorithm that is used to detect errors in an assembled product. The algorithm is trained on synthetic images generated using the CAD model of the different components of the assembly. The CAD model guides the inspection algorithm through its training stage by addressing the different types of variations that occur during manufacturing and assembly. Those variations are classified into those that can affect the functionality of the assembled product and those that are unrelated to its functionality. Using synthetic images in the training process adds to the versatility of the technique by removing the need to manufacture multiple prototypes and control the lighting conditions. Once trained on synthetic images, the algorithm can detect assembly errors by examining real images of the assembled product. The effectiveness of the system is illustrated on a typical mechanical assembly.This work was supported by National Science Foundation grant number CDR 8803017 to the Engineering Research Center for Intelligent Manufacturing Systems, National Science Foundation grant number MIP93-00560, an AT&T Bell Laboratories PhD Scholarship, and the NEC corporation

Camera and light placement for automated assembly inspection

Includes bibliographical references.Visual assembly inspection can provide a low cost, accurate, and efficient solution to the automated assembly inspection problem, which is a crucial component of any automated assembly manufacturing process. The performance of such an inspection system is heavily dependent on the placement of the camera and light source. This article presents new algorithms that use the CAD model of a finished assembly for placing the camera and light source to optimize the performance of an automated assembly inspection algorithm. This general-purpose algorithm utilizes the component material properties and the contact information from the CAD model of the assembly, along with standard computer graphics hardware and physically accurate lighting models, to determine the effects of camera and light source placement on the performance of an inspection algorithm. The effectiveness of the algorithms is illustrated on a typical mechanical assembly.This work was supported by National Science Foundation grant number CDR 8803017 to the Engineering Research Center for Intelligent Manufacturing Systems, National Science Foundation grant number MIP93-00560, an AT&T Bell Laboratories PhD Scholarship, and the NEC Corporation

'The drugs did for me what I couldn’t do for myself’: A qualitative exploration of the relationship between mental health and amphetamine-type stimulant (ATS) use

Substance use and mental ill health constitute a major public health burden, and a key global policy priority is to reduce illicit and other harmful substance use. Amphetamine-type stimulants (ATS) are the second most used class of illicit drugs and a range of mental health issues have been documented amongst users. This paper explores the relationship between mental health and ATS use, through a thematic analysis of qualitative interviews with n=18 current and former ATS users in England. The findings are presented by trajectory point of; (1) Initiation of ATS use; (2) continued and increased ATS use; and (3) decreased and remitted ATS use. This work helps to develop understanding around the complex and bidirectional relationship between ATS use and mental health. Many ATS users lead chaotic lives and engage in multiple risk behaviours; however, there is a need to better understand and conceptualise the dynamic interaction between different individual, social, environment and cultural factors that determine individuals’ mental health and substance use. There is no ‘one size fits all’ approach to prevention and treatment, and these findings highlight the need for more joined-up, tailored, and holistic approaches to intervention development

Wire + Arc Additive Manufacturing

Depositing large components (>10 kg) in titanium, aluminium, steel and other metals is possible using Wire + Arc Additive Manufacturing. This technology adopts arc welding tools and wire as feedstock for additive manufacturing purposes. High deposition rates, low material and equipment costs, and good structural integrity make Wire+Arc Additive Manufacturing a suitable candidate for replacing the current method of manufacturing from solid billets or large forgings, especially with regards to low and medium complexity parts. A variety of components have been successfully manufactured with this process, including Ti–6Al–4V spars and landing gear assemblies, aluminium wing ribs, steel wind tunnel models and cones. Strategies on how to manage residual stress, improve mechanical properties and eliminate defects such as porosity are suggested. Finally, the benefits of non-destructive testing, online monitoring and in situ machining are discussed