4 research outputs found
Design and baseline characteristics of the finerenone in reducing cardiovascular mortality and morbidity in diabetic kidney disease trial
- Author
- Abdel-Rahman Emaad
- Abhayaratna Walter
- Abramof Ness Rosane
- Acosta Idalia
- Adams Atoya
- Adawi Faiad
- Adler Sharon
- Ahmed Fayzal
- Aizenberg Diego
- Ajani Dilawar
- Al-Karadsheh Amer
- Albota Adrian
- Alferi Dino
- Alicic Radica
- Alla Sreedhara
- Allison D
- Almeida Edgar
- Alpizar Salazar Melchor
- Amer Joseph
- Amod Aslam
- Andrawis Nabil
- Antonio Bossi Carlo
- Antsiferov Mikhail
- Antunes Daniela
- Araki Hideo
- Arango Clara
- Arcos Edgar
- Arif Ahmed
- Arif Imrozia
- Arkhipov Mikhail
- Armaly Zaher
- Aroca Gustavo
- Asprusten Emil
- Atar Shaul
- Avila Pardo Sandro
- Awad Ahmed
- Axthelm Christoph
- Azizad Masoud
- Azizah Aziz Nor
- B Brouwer C
- Babikova Jana
- Babkin Andrey
- Badak Ozer
- Bahrami Michael
- Bajcsi Dora
- Baker John
- Bala Cornelia
- Ballesteros Rosa
- Bansal Shweta
- Barag Steven
- Barakzoy Ahmad
- Baranov Vitaliy
- Barbarash Olga
- Barbonta Hortensia
- Barney Mark
- Barre Paul
- Barrera Sandra
- Barreto Carlos
- Barreto Germ\ue1n
- Bartolacci In\ue9s
- Bashir Khalid
- Bashkin Amir
- Bastidas Adrian Miriam
- Bautista Albert
- Bautista Jose
- Bech Jesper
- Beddhu Srinivasan
- Beltr\ue1n L\uf3pez Nelly
- Ben Chetrit Sydney
- Benitez Diego
- Benjamin Sabrina
- Berar Yanay Noa
- Berenji Ramin
- Bertram Pitt
- Bertsch John
- Besada Diego
- Bhana Sindeep
- Bhargava Anuj
- Bilz Stefan
- Birkenfeld Andreas
- Birriel Jose
- Bittar Julio
- Blanco Guillermo
- Bleich David
- Boletis Ioannis
- Bondarets Iryna
- Bonora Enzo
- Bornfreund Jonathan
- Boshnyashka Radostina
- Botelho Roberto
- Botero Rodrigo
- Botsyurko Volodymyr
- Bouarich Hanane
- Brada Michal
- Brandao Ilidio
- Brar Harjeet
- Braun Hermann
- Brezina Jiri
- Brian Susan
- Brietzke Stephen
- Brito Claudia
- Bruchfeld Annette
- Bruno Giorda Carlo
- Brusco Osvaldo
- Bu Ruifang
- Bucek Petr
- Buganova Ingrid
- Burgner Anna
- Busch Klaus
- Busch Robert
- Butrymowicz Patrycja
- C Bakker R
- C\ue1rdenas Tatiana
- Caceaune Elena
- Cai Hanqing
- Calabr\uf2 Paolo
- Calero Francesca
- Canadas Rafael
- Canani Luis
- Caramori Maria
- Cardona Jose
- Cariou Bertrand
- Carlo Maggi Davide
- Carlos Palma Juan
- Carlos Prieto Juan
- Carlson Brian
- Carpio Jose
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- Case Christopher
- Castro Cristina
- Catindig Elizabeth
- Catrinoiu Doina
- Cayli Murat
- Cereto Castro Fernando
- Cerqueira Maria
- Chahin Mariano
- Chang Chiz-Tzung
- Chantrel Fran\ue7ois
- Chen Dejun
- Chen Nan
- Chen Qinkai
- Cheng Jinluo
- Chernikova Viktoriia
- Chernin Gil
- Chernyavskaya Elena
- Chew Wong Alfredo
- Christina Nowack
- Chuang Lee-Ming
- Chung ChoonHee
- Ciechanowski Kazimierz
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- Cigarr\ue1n Guldris Secundino
- Cimino Roberto
- Clavel Sylvaine
- Clodi Martin
- Cobos Jorge
- Colman Peter
- Colquhoun David
- Constantin Ciprian
- Contzen Christel
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- Coronel Julian
- Cortes-Maisonet Gregorio
- Cortes-Maisonet Gregorio
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- Cristina Gregorini Maria
- Cruz Humberto
- Cruzado Garrit Josep
- Cure Carlos
- Curiac Dan
- Cutfield Rick
- Dandillaya Ramprasad
- Dang Cuong
- Danos Peter
- Darawsha Mahmud
- de \uc1lvaro Fernando
- de Paula Rogerio
- Deerochanawong Chaicharn
- Degenhardt Stefan
- Demko Arkadiy
- Derwahl Karl
- Dhanireddy Soni
- Din Zia
- Distiller Larry
- Dixon Bradley
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- Dong Youping
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- Ebenbichler Christoph
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- Frank Malin
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- H Boonstra A
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- Habwe Violet
- Hagemeier Robert
- Hagenow Andreas
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- Wu Mai-Szu
- Wu Ming-Ju
- Wu Tianfeng
- Wudi Krisztina
- Wuerzner Gregoire
- Wynne Katie-Jane
- Xing Changying
- Xiong Fei
- Xu Ning
- Xu Xudong
- Yagil Yoram
- Yajima Ken
- Yakhontov Davyd
- Yale Jean-Francois
- Yamada Daishiro
- Yamada Masayo
- Yamagata Kazuo
- Yamakawa Fumiko
- Yamakawa Ken
- Yamasaki Yoshimitsu
- Yambe Yuko
- Yanai Hidekatsu
- Yang Jinkui
- Yasuda Tetsuyuki
- Yenicerioglu Yavuz
- Yeung Vincent
- Yilmaz Huseyin
- Yin Aiping
- Yoncheva-Mihaylova Mariana
- Young Park Cheol
- Yuan Lee Li
- Yupanqui Hern\ue1n
- Yuryev Michael
- Zakharova Elena
- Zalevskaya Alsu
- Zanozina Olga
- Zaoui Philippe
- Zeig Steven
- Zeng Longyi
- Zhang Hao
- Zhang Yanlin
- Zhang Ying
- Zhao Zhiquan
- Zhdanova Elena
- Zheng Hongguang
- Zhong Ling
- Zhong Liyong
- Zhu Dalong
- Zhukova Larisa
- Zilahi Zsolt
- Zsom Marianna
- Zukermann Robert
- Zykova Tatyana
- Publication venue
- 'S. Karger AG'
- Publication date
- 01/01/2019
- Field of study
Background: Among people with diabetes, those with kidney disease have exceptionally high rates of cardiovascular (CV) morbidity and mortality and progression of their underlying kidney disease. Finerenone is a novel, nonsteroidal, selective mineralocorticoid receptor antagonist that has shown to reduce albuminuria in type 2 diabetes (T2D) patients with chronic kidney disease (CKD) while revealing only a low risk of hyperkalemia. However, the effect of finerenone on CV and renal outcomes has not yet been investigated in long-term trials.
Patients and Methods: The Finerenone in Reducing CV Mortality and Morbidity in Diabetic Kidney Disease (FIGARO-DKD) trial aims to assess the efficacy and safety of finerenone compared to placebo at reducing clinically important CV and renal outcomes in T2D patients with CKD. FIGARO-DKD is a randomized, double-blind, placebo-controlled, parallel-group, event-driven trial running in 47 countries with an expected duration of approximately 6 years. FIGARO-DKD randomized 7,437 patients with an estimated glomerular filtration rate >= 25 mL/min/1.73 m(2) and albuminuria (urinary albumin-to-creatinine ratio >= 30 to <= 5,000 mg/g). The study has at least 90% power to detect a 20% reduction in the risk of the primary outcome (overall two-sided significance level alpha = 0.05), the composite of time to first occurrence of CV death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for heart failure.
Conclusions: FIGARO-DKD will determine whether an optimally treated cohort of T2D patients with CKD at high risk of CV and renal events will experience cardiorenal benefits with the addition of finerenone to their treatment regimen.
Trial Registration: EudraCT number: 2015-000950-39; ClinicalTrials.gov identifier: NCT02545049
Empagliflozin and Kidney Function Decline in Patients with Type 2 Diabetes: A Slope Analysis from the EMPA-REG OUTCOME Trial
- Author
- Abu Hassan M.
- Adawi F.
- Adojaan B.
- Agafyina A.
- Aguilar-Salinas C.
- Agung P.
- Ahmad N. Nik
- Aiello A.
- Aizenberg D.
- Ajani D.
- Al-Windy N.
- Allemant Maldonado A.
- Aloi J.
- Alpizar Salazar M.
- Alzohaili O.
- Amod A.
- Andersen J.
- Anderson M.
- Andrade L.
- Anspach R.
- Antoli A.
- Antonypillai C.
- Aquitania G.
- Aravind S.
- Arca M.
- Arena C.
- Arif A.
- Aronoff S.
- Artola S.
- Arutyunov G.
- Aure P.
- Austin B.
- Avramidis I.
- Awad A.
- Ayoub J.
- Badgandi M.
- Balasko A.
- Balic S.
- Ball E.
- Bantwal G.
- Barager W.
- Baranowski M.
- Barbarash O.
- Barbarich V.
- Barbonta D.
- Barker B.
- Bashkin A.
- Bayly K.
- Belenkiy D.
- Benatar J.
- Benhalima Katrien
- Benroubi M.
- Bergenstal R.
- Bergman B.
- Berlingieri J.
- Bertolami M.
- Berz A.
- Betti R.
- Bittar N.
- Blakney E.
- Blaze K.
- Blignaut S.
- Boesgaard T. Wellov
- Bononi P.
- Borges J.
- Boscia J.
- Boucher P.
- Bousboulas S.
- Bowden R.
- Boyarkin M.
- Brandon D.
- Bratcher C.
- Brazao M.
- Bressler P.
- Breton C.
- Bretton E.
- Brito M.
- Brockmyre A.
- Broedl Uli C.
- Brusco O.
- Bucci M.
- Bulugahapitiya D.
- Burgess L.
- Burr R.
- Burtchuladze T.
- Butler M.
- Buynak R.
- Bystrova A.
- Cahill T.
- Calabro P.
- Caldwell I.
- Camafort M.
- Capiau L.
- Cardona Munoz E.
- Castro M.
- Catrinoiu D.
- Cefalu W.
- Chachati A.
- Chacra A.
- Chan Y.
- Chandramouli A.
- Chang H.
- Chang K.
- Chappell D.
- Chauhan A.
- Chaykin L.
- Chee K.
- Chehayeb R.
- Chen J.
- Cherlin R.
- Chiang C.
- Choksi M.
- Choukroun G.
- Christensen P.
- Christensen T.
- Chumakova G.
- Cignarelli M.
- Clavel S.
- Clayton D.
- Colfer H.
- Colivicchi F.
- Colombo H.
- Connery L.
- Cosma D.
- Couffinhal T.
- Courreges J.
- Crisan C.
- Cruz H.
- Cuddihy R.
- Curtis C.
- d'Emden M.
- Daugenet C.
- de Jong A.
- De La Rosa R.
- De Loredo L.
- De Los Santos G.
- de Teresa L.
- Deerochanawong C.
- Dekelver P.
- del Canizo F.
- Dela Llana A.
- Delgado Torres C.
- Denker P.
- Deshpande N.
- Devers M.
- Diaz J.
- Dinato M.
- DiSanto L.
- Distiller L.
- Drexel H.
- Drvodelic-Sunic E.
- Duarte R.
- Duarte S.
- Dudas M.
- Dulgeroff A.
- Dunmyer S.
- Eagerton D.
- Eder F.
- Efrati S.
- Eliaschewitz F.
- Emanuel S.
- Engelbrecht J.
- Esip V.
- Estour B.
- Faludi A.
- Farfan J.
- Farias J.
- Farmer I.
- Farris N.
- Fasching P.
- Feld L.
- Feldman G.
- Felicio J.
- Fernandez-Cruz A.
- Ferre Pacora F.
- Fideleff H.
- Fillipova E.
- Fioretto P.
- First B.
- Fishman N.
- Fitz-Patrick D.
- Fliesser-Goerzer E.
- Flippo G.
- Flores F.
- Fogelfeld L.
- Foo S.
- Formagne L.
- Fossum C.
- Fowler W.
- Freedman Z.
- Fucili A.
- Fung Y.
- Furui K.
- Gabra N.
- Gallardo Rojas W.
- Garcia Hernandez P.
- Garcia Soria M.
- Garcia-Ortiz L.
- Gardner T.
- Garg N.
- Geloneze Neto B.
- Geroo L.
- Ghaisas N.
- Ghani R. Abdul
- Giorgadze E.
- Giugliano G.
- Glonti S.
- Gnasso A.
- Godlevska O.
- Godoy Junchaya J.
- Goldoni V.
- Gomez Peralta F.
- Gonkel F.
- Gonzales Bravo L.
- Gonzalez-Campoy J.
- Gottschlich G.
- Gouet D.
- Govind U.
- Goytia-Leos D.
- Graf R.
- Green C.
- Green F.
- Groop Per-Henrik
- Gross J.
- Gupta J.
- Gupta M.
- Gupta S.
- Gutlapalli K.
- Gwon H.
- Hadjadj S.
- Halimi J.
- Halpern A.
- Halpern S.
- Hammond G.
- Hansen V.
- Hansen Val R.
- Hantel Stefan
- Hassani F.
- Hayashida C.
- Heerspink Hiddo J. L.
- Heggen E.
- Henein S.
- Hermans M.
- Hernandez M.
- Herskovits T.
- Heurich E.
- Hieshima K.
- Higashiue S.
- Hippert R.
- Hiramatsu N.
- Hissa M.
- Hoffman J.
- Hoffman K.
- Hojo F.
- Hollanders G.
- Hong T.
- Hoogslag P.
- Houchin V.
- Howard T.
- Huang C.
- Huffman D.
- Huntley R.
- Hurley D.
- Hurtig U.
- Hwang J.
- Iabluchanskyi M.
- Iglesias M.
- Iglesias R.
- Imran S. A.
- Inzucchi Silvio E.
- Ip T.
- Istratoaie O.
- Ito M.
- Izumino K.
- Jacks R.
- Jaffe A.
- Jain M.
- Jain S.
- Jakovlev U.
- Jaramillo N.
- Jardula M.
- Javashvili L.
- Jeong J.
- Jeong M.
- Jinnouchi H.
- Juarez M.
- Juhasz F.
- Juhl H.
- Jurgens J.
- Jurisic-Erzen D.
- Juwana Y.
- Kadir K. Abdul
- Kaewsuwanna P.
- Kang K.
- Karamitsos K.
- Karim S.
- Karlsson T.
- Karlsson Thomas
- Kaser S.
- Kasper J.
- Kaveh K.
- Kawamitsu K.
- Kayne D.
- Kereiakes D.
- Kerstein H.
- Keymeulen B.
- Khan B.
- Khetagurova F.
- Khokhlov A.
- Khomasuridze A.
- Kim D.
- Kim H.
- Kim Y.
- Knopke C.
- Kockaerts Y.
- Koitka-Weber Audrey
- Kondo Y.
- Konieczny M.
- Kooy A.
- Koppel W.
- Kovalyova O.
- Kowaloff E.
- Kowalyk S.
- Kragten J.
- Krarup T.
- Krasilnikova E.
- Krebs J.
- Krekels M.
- Kriangsak P.
- Krzyzagorska E.
- Kulkarni A.
- Kurashvili G.
- Kurashvili R.
- Kus W.
- Lagrutta M.
- Lai W.
- Laliotis A.
- Lamkanfi F.
- Langslet G.
- Lanno R.
- Lantseva O.
- Lastuvka J.
- Lee S.
- Lehman R.
- Leitao A.
- Lema Osores J.
- Lemarie B.
- Lemis P.
- Lerman S.
- Levins P.
- Levinson L.
- Lewis D.
- Lewy-Alterbaum L.
- Libov I.
- Lichiardopol R.
- Lienart F.
- Lihn A. Saetre
- Lim D.
- Lima Filho M.
- Linares J.
- Lindenbaum J.
- Ling K.
- Liss J.
- Lisson R.
- Liwag A.
- Llorente I.
- Lochnan H.
- Lochorn G.
- Lombaard J.
- Lominadze Z.
- Longshaw K.
- Lopez Jaramillo P.
- Lu Y.
- Lubi M.
- Luger A.
- Lund P.
- Mabire P.
- MacAdams M.
- Mach M.
- Machkova M.
- MacRury S.
- Maffei L.
- Magee M.
- Mahood K.
- Malano J.
- Maldonado N.
- Manenti E.
- Manes C.
- Mangklabruks A.
- Marandi T.
- Marchionni N.
- Mariano H.
- Marsilii A.
- Matfin G.
- Mathieu C.
- Mattheus Michaela
- Maw K.
- Mayfield R.
- Maynard B.
- Mazen E.
- McKnight J.
- Medagama U.
- Meleshkevich T.
- Mesa J.
- Metreveli D.
- Mevissen H.
- Mezzetti A.
- Micher Escalante D.
- Middleton A.
- Militaru C.
- Miranda F.
- Miranda-Palma B.
- Mirosevic G.
- Mitha E.
- Mohamed W. Wan
- Mohan V.
- Mokshagundam S.
- Molter D.
- Monno S.
- Monte O.
- Monteiro P.
- Moodley R.
- Mookadam M.
- Morawski E.
- Moreno B.
- Moro E.
- Mortelmans J.
- Mosely J.
- Mulder H.
- Mustafa N.
- Nadareishvili L.
- Nagy K.
- Naidoo D.
- Naidoo V.
- Naidu J.
- Nassim O.
- Navarro J.
- Nicasio J.
- Nierop P.
- Nikolaev K.
- Nortje H.
- Nunes Salles J.
- O'Brien I.
- Obiekwe O.
- Obrezan A.
- Ocicka-Kozakiewicz A.
- Ogorek M.
- Okubo M.
- Oldenburg-Ligtenberg P.
- Olsovsky J.
- Omar M.
- Onishi Y.
- Orlowska-Kunikowska E.
- Orr R.
- Osea E.
- Oskin T.
- Ouellett A.
- Ozaki R.
- Paine W.
- Pandey A.
- Panelo A.
- Pappas S.
- Park H.
- Park S.
- Parmar P.
- Patel A.
- Patel N.
- Patkay J.
- Patrick J.
- Paulweber B.
- Pearson E.
- Peniston J.
- Pereg V.
- Perez G.
- Persu A.
- Petit C.
- Petrov A.
- Petunina N.
- Piaditis G.
- Piesiewicz W.
- Pillai M.
- Pinto L.
- Pish R.
- Piyayotai D.
- Pluto T.
- Podgorski G.
- Pop L.
- Potemkin V.
- Pozzilli P.
- Prager R.
- Pramono B.
- Prawer J.
- Premchand R.
- Pretorius M.
- Purisch S.
- Queiros J.
- Ramoncito H.
- Rassi N.
- Rawls R.
- Rea R.
- Reddy S.
- Reed J.
- Reeves M.
- Reggiani G. Marchesini
- Remaud P.
- Rendell M.
- Rha S.
- Richards R.
- Richwine R.
- Ridderstrale M.
- Rigla M.
- Riley E.
- Riser J.
- Rita H.
- Roberson K.
- Roderos O.
- Rodriguez Escudero A.
- Rogado C.
- Roldan Concha Y.
- Ronner E.
- Roodt A.
- Rosales R.
- Rosenfeld J.
- Rosenstock J.
- Rossolko L.
- Rothman J.
- Saban J.
- Sadhu N.
- Saksono H. Dante
- Salamon C.
- Salgado V.
- Samoylov O.
- Sanchez G.
- Sandberg M.
- Sanders D.
- Santini M.
- Saraiva J.
- Satarasinghe R.
- Saxman K.
- Schaper N.
- Schear M.
- Scheen A.
- Schernthaner G.
- Schiff E.
- Schmid H.
- Schnack C.
- Scott R.
- Segura J.
- Seidman B.
- Seidner M.
- Selvanayagam J.
- Semplicini A.
- Seung K.
- Sgarbi J.
- Shah S.
- Shamanna P.
- Shandilya L.
- Shanik M.
- Shapiro J.
- Shepard M.
- Shin M.
- Shomali M.
- Silva A.
- Simpson R.
- Siswanto B.
- Sitar S.
- Siu S.
- Siyambalapitiya S.
- Skokowska E.
- Sobral do Rosario F.
- Sofley C.
- Soldyshev R.
- Somasundaram N.
- Soufer J.
- Sparby J.
- Spyra J.
- St Amour E.
- Stedman M.
- Storms G.
- Strivay M.
- Stroger John H.
- Strout C.
- Suarez C.
- Suastika K.
- Sum C.
- Suwanwalaikorn S.
- Suzuki A.
- Sy R.
- Syed M.
- Szentpeteri I.
- Tabak A.
- Taddei S.
- Tahk S.
- Takahashi H.
- Takahashi M.
- Takenaka T.
- Tamas G.
- Tamayo R.
- Tan G.
- Tan K.
- Tan R.
- Tanggo Y.
- Tarasov N.
- Tarnow L.
- Teixeira J.
- Teltser M.
- Tentolouris N.
- Terront Lozano M.
- Tiburcio A.
- Toledo R.
- Toplak H.
- Toscano V.
- Toural E.
- Trescoli C.
- Tsang C.
- Tseluyko V.
- Tusek S.
- Ubani A.
- Ulla M.
- Ullal J.
- Ur E.
- Urhammer S.
- Urina M.
- Urquiaga Calderon J.
- Uwaifo G.
- van Bemmel T.
- Van de Borne P.
- Van Gaal Luc
- van Soest J.
- Van Zyl L.
- Vantroyen D.
- Varzic S. Canecki
- Vawda H.
- Velazquez F.
- Velez M.
- Venter T.
- Vercammen C.
- Vereecken G.
- Verhoeven R.
- Vidal J.
- Vidrio Velazquez M.
- Viergever P.
- Virsaladze D.
- Voloshyna O.
- von Eynatten Maximilian
- Vorokhobina N.
- Vryonidou A.
- Vykhovanyuk I.
- Wahlen J.
- Wahono S. Djoko
- Wainstein J.
- Waitman J.
- Wakida Y.
- Waldron M.
- Wang J.
- Wanner Christoph
- Warren M.
- Wasserman A.
- Wehmeier K.
- Weiner P.
- Weinrauch L.
- Weiss R.
- Welch M.
- Wen M.
- Wilks K.
- Wittmer B.
- Woerle Hans-Juergen
- Wojnowski L.
- Woo V.
- Wood J.
- Wyatt N.
- Wysham C.
- Yakhontova P.
- Yang J.
- Yeh H.
- Yoon J.
- Yupanqui Lozno H.
- Zalevskaya A.
- Zanella M.
- Zaniewski-Singh M.
- Zaoui P.
- Zapata L.
- Zateyshchikov D.
- Zayour D.
- Zetu C.
- Zinman B.
- Zinman Bernard
- Zmuda W.
- Zotov S.
- Zwiers G.
- Publication venue
- Publication date
- 01/01/2018
- Field of study
Apixaban versus warfarin in patients with atrial fibrillation
- Author
- A Agarwal
- A Ahsan
- A Ajala
- A Al-Mudamgha
- A Alexander
- A Alfieri
- A Alings
- A Alwail
- A Bakhai
- A Barsotti
- A Bartkowiak
- A Bauer
- A Bazylevych
- A Bazzi
- A Bethencourt González
- A Bharani
- A Bittersohl
- A Boruczkowska-Kaszkowiak
- A Boyle
- A Bragina
- A Bredero
- A Brockmyre
- A Budaj
- A Buxton
- A Caccavo
- A Cassettari
- A Chhabra
- A Chmielinski
- A Cohen
- A Cooke
- A Cziraki
- A D'Angelo
- A De Paola
- A Dharmadhikari
- A Dowell
- A Francis
- A Gabito
- A Galicia
- A Ghirarduzzi
- A Golovach
- A Gordienko
- A Govorin
- A Hamad
- A Hershson
- A Hetzel
- A Hrabar
- A Ivleva
- A Jacob
- A Jones
- A Kabour
- A Kastanayan
- A Katona
- A Kelly
- A Koniakhin
- A Kovács
- A Lebowitz
- A Levin
- A Liu
- A Lorga Filho
- A Lowy
- A MacKinnon
- A Magnano
- A Marmor
- A Matsushima
- A Meholick
- A Mirode
- A Mohácsi
- A Moriarty
- A Muniz
- A Mügge
- A Mügge
- A Naik
- A Nambiar
- A Obrezan
- A Ocicka-Kozakiewicz
- A Pandey
- A Papp
- A Parkhomenko
- A Patel
- A Peeters
- A Pálinkás
- A Quick
- A Rabelo Alves Jr
- A Reyes
- A Rodriguez
- A Roman
- A Rubin
- A Salacata
- A Salajan
- A Samal
- A Sanchez
- A Schaap
- A Sinopalnikov
- A Skolnick
- A Solomon
- A Svistov
- A Ugarriza
- A Utech
- A Vértes
- A Wade
- A Warner
- A Weiss
- A Wellford
- A Yagensky
- Al-Khalidi H. R.
- Aldo Maggioni
- Alexander J. H.
- Alexander Parkhomenko
- Ali Zomorodi
- Allison Handler
- Alvaro Albrecht
- Alvaro Avezum
- Andreas Terent
- Andrew Burr
- Anna Stenborg
- Anne Delvaux
- Ansell J.
- Antonio Carlos Lopes
- Antonio G Hermosillo
- Antonio M W Alings
- Arnaud Bastien
- Atar D.
- Avezum A.
- Axel Akerblom
- B Bachhuber
- B Beanblossom
- B Blue
- B Bruneel
- B Bryhni
- B Coutu
- B Garbelini Jr
- B Gervais
- B Gorenek
- B Griewing
- B H Oh
- B Hattler
- B Iteld
- B Jackson
- B Kowalski
- B Lachterman
- B Lasko
- B Lewis
- B Malipeddi
- B McClements
- B Peart
- B Pieske
- B Platt
- B Podogrodzka
- B Ramagiri
- B Ramjattan
- B Schifferdecker
- B Sidorenko
- B Srinivasasastry
- B Stockins
- B Winkelmann
- B Wollaert
- B Yu
- B Øie
- Bahit M. C.
- Basil S Lewis
- Bernard J Gersh
- Bradley Kolls
- Byung-Hee Oh
- C Arean Martinez
- C Arsenescu Georgescu
- C Beneitez
- C Bredlau
- C Calvo Vargas
- C Chavez
- C Christersson
- C Corder
- C Cuneo
- C D Tseng
- C Dézsi
- C East
- C Erol
- C Fortin
- C G Fierbinteanu-Braticevici
- C Gonzalez Juanatey
- C Hassel
- C Höglund
- C J Lindholm
- C JerJes-Sanchez
- C Kaoru Indio do Brasil
- C Levin
- C Lovell
- C Massey
- C McPherson
- C Mihaela Tanaseanu
- C Muratore
- C Olivieri
- C Pincetti
- C Pop
- C Powers
- C Poy
- C Raffo
- C Riojas
- C Rios Vasquez
- C Rodriguez-Fierro
- C Russo
- C Sofley
- C Sotolongo
- C Toftager Larsen
- C Torp-Pedersen
- C Tuxen
- C Van der Zwaan
- C W Lee
- C Weimar
- C Y Rhim
- C Yu
- C Zaidman
- Carlo Lombardi
- Cetin Erol
- Cheryl Bushnell
- Christoph Varenhorst
- Claes Held
- D Agarwal
- D Albuquerque
- D Ashby
- D Belenky
- D Borts
- D Brieger
- D Chiu
- D Clark
- D Colan
- D Cross
- D De Jong
- D Dohan
- D Donovan
- D Duplyakov
- D Dutka
- D El Allaf
- D Fell
- D Fischer
- D G Shin
- D Gaita
- D Garcia
- D Goldscher
- D Gottlieb
- D Gupta
- D Hassman
- D Humiston
- D Isaza
- D J Choi
- D Jiang
- D Kelbe
- D Kereiakes
- D Lighezan
- D Linden
- D Lok
- D Mercado
- D Mishkel
- D Morales
- D Moreira
- D Murdoch
- D O'Keefe
- D Perloff
- D Piskorz
- D Precoma
- D Rhodes
- D Riff
- D Rupka
- D Santos
- D Spence
- D Stapleton
- D Travis
- D Tudor Zdrenghea
- D Van Hamersveld
- D Vinereanu
- D Vogel
- D Walters
- D Young
- D Zotov
- Dan Atar
- Daniel Isaza
- David Garcia
- Denis Xavier
- Diaz R.
- Dipen Parikh
- Dragos Vinereanu
- E Ball
- E Blumberg
- E Carasca
- E Engeron
- E Flores
- E Galve
- E Gomez
- E Hasbani
- E Haskel
- E Julian Chuquiure-Valenzuela
- E Klainman
- E Kosinski
- E Lopez Rosas
- E Manenti
- E Mazur
- E Morales-Palomares
- E Mouhayar
- E Panchenko
- E Pelloso
- E Privalova
- E Ramos
- E Retyk
- E Richiardi
- E Rivera
- E Sabbah
- E Schwarz
- E Sivkova
- E Suprun
- E van Nieuwenhuizen
- E von Hodenberg
- E Zemtsovsky
- E Zidkova
- Easton J. D.
- Elaine M Hylek
- Elaine M Hylek
- Emil Hagstrom
- Erik Lundstrom
- Eva Nemeth
- Ezekowitz J. A.
- F Agnone
- F Al-Khalili
- F Al-Khalili
- F Albrecht
- F Bai
- F Collado
- F Collado
- F De Leon
- F de Looze
- F de Looze
- F de Looze
- F de Looze
- F Dunn
- F Grondin
- F Kouichi
- F Lakatos
- F Maislos
- F Medina
- F Olías de la Cruz
- F Provenier
- F Rolandi
- F Schlachetzki
- F St Maurice
- F Stockenhuber
- F Stögbauer
- F Verheugt
- F Villaça Guimaraes Filho
- F Zhang
- Fernando Lanas
- Flaker G.
- Fred Fiedorek
- Freek W A Verheugt
- G Andrei Dan
- G Arutyunov
- G Aycock
- G Boxho
- G Brooks
- G Bustamante
- G Casolo
- G Dzyak
- G Feldman
- G Filonenko
- G Ford
- G Gojanur
- G Hanovich
- G Ignatenko
- G Jensen
- G Kahrmann
- G Kamalov
- G Kania
- G Lavabre
- G Lip
- G Lu
- G Lupkovics
- G Lysenko
- G Mairesse
- G McInnes
- G Noble
- G Oliveira
- G Popik
- G Rasmanis
- G Reis
- G Rogelio
- G Sabe-Affaki
- G Sosa-Suarez
- G Stenzel
- G Syan
- Garcia D.
- George Wyse
- Geraldes M.
- Gersh B. J.
- Golitsyn S.
- Goto S.
- Granger C. B.
- Greg Flaker
- Greg Stashenko
- H B Gowdappa
- H Colombo
- H F Vöhringer
- H Hamer
- H Ikeda
- H Jure
- H Kadr
- H Karunaratne
- H Kihara
- H Kultursay
- H Lastiri
- H Li
- H Li
- H Luciardi
- H Michels
- H Moore
- H Murata
- H Nachtergaele
- H Parikka
- H Po
- H Poppert
- H Punatar
- H Ramos
- H Reis
- H Salem
- H Striekwold
- H Takagi
- H Tan
- H Weich
- H Yoshii
- Hanna M.
- Hans-Christoph Diener
- Helio Guimaraes
- Hermosillo A. G.
- Hohnloser S. H.
- Hongqiu Yang
- Horowitz J.
- Hylek E. M.
- I Aisiku
- I Benedek
- I Bereznyakov
- I Chernichka
- I Chopey
- I Findlay
- I Friedlander
- I Gordeev
- I Hernandez Santamaria
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- I Libov
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- I Morales Gonzalez
- I Niazi
- I Plaza Pérez
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- I Szakál
- I Vykhovanyuk
- I Z Abidin
- J A Wang
- J Agaiby
- J Alejandro Cordero-Cabra
- J Amerena
- J Amin
- J Anderson
- J Arneja
- J Bakai
- J Berlingieri
- J Brachmann
- J Bruguera
- J Camm
- J Cannon
- J Cebe
- J Cervantes-Escarcega
- J Cha
- J Cobos
- J Cooke
- J Cordero-Sepulveda
- J Counsell
- J Cuadrado
- J Davies
- J Dean
- J Donald Easton
- J Duggal
- J E Otterstad
- J Egido Herrero
- J Estepo
- J F Saraiva
- J Flather
- J Fleming
- J Foley
- J Galizia
- J Garcia Pulido
- J Gerber
- J Gois
- J Gonzalez Guerra
- J Gonzalez Hermosillo
- J Graff
- J Griffin
- J H Bae
- J H Gómez Gómez
- J H Sung
- J Harenberg
- J Healey
- J Hemphill
- J Herlitz
- J Horowitz
- J Hysing
- J Ilvento
- J Ip
- J J V McMurray
- J Jaber
- J Jorge
- J Joseph
- J Jung
- J Kappler
- J Kasprzak
- J Kobayashi
- J Kramer
- J L Aziz
- J L Corbelli
- J LaFata
- J Lang
- J Leroy
- J Li
- J Lomholdt
- J Mansourati
- J Margolis
- J Marino
- J McCriskin
- J Melin
- J P Pan
- J Phillips
- J Plomp
- J Porterfield
- J Quartner
- J Ricci
- J Rogers
- J Roos
- J Roquer
- J Roth
- J Schmedtje Jr
- J Seger
- J Serena Leal
- J Serra
- J Silveira
- J Spinar
- J Stepinska
- J Strand
- J Strobel
- J Takács
- J Thorne
- J Tomcsányi
- J Updegrove
- J Usedom
- J Vazquez-Tanus
- J Vijgen
- J Viljoen
- J Villacastin
- J Vivancos
- J Waites
- J Walters
- J Webster
- J Welker
- J White
- J Wunderlich
- Jack Ansell
- Jansky P.
- Jean-Lucien Rouleau
- Jeffrey Berger
- Jennifer Vergara
- Joan Vidal
- John Amerena
- John H Alexander
- John H Alexander
- John Horowitz
- John J V McMurray
- John J V McMurray
- John Vavalle
- Jose Luis Lopez-Sendon
- Jozef Bartunek
- Jun Zhu
- Justin A Ezekowitz
- Jyotsna Garg
- K Amosova
- K Bybee
- K Cao
- K Carr
- K Cohen
- K Curry
- K Danisa
- K E Pedersen
- K Egstrup
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- K Klancke
- K Kurrelmeyer
- K Lee
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- K Parr
- K S Park
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- K Saunders
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- K Yusoff
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- Keven Griffith
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- L Bodanese
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- L Li
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- L Smith
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- L Tami
- L Toce
- L van Zyl
- L Wawrzynska
- L Winkler
- L Yao
- L Zimerman
- L Zimmet
- Lars Wallentin
- Leandro Echenique
- Lewis B. S.
- Lisa Hatch
- Liu Lisheng
- Lopes R. D.
- Lopez-Sendon J. L.
- Lorraine Rossi
- Luciana Armaganijan
- Luis Segura
- M A Paz Bermejo
- M Albazzaz
- M Alcocer Gamba
- M Anderson
- M B Labarta
- M Basson
- M Blagden
- M Blostein
- M Boileau
- M Borschivsky
- M Boyarkin
- M Brack
- M Bronisz
- M Buerke
- M C Valéria Braile
- M Callander
- M Casey
- M Cech
- M Cecilia Bahit
- M Chiariello
- M Cinteza
- M Coutinho
- M Daniels
- M Davis
- M De los Rios Ibarra
- M Donati
- M Dotani
- M Dunaj
- M Fichino
- M Finneran
- M Fulwani
- M Gadkari
- M Galewicz
- M Galli
- M Garrido
- M Gelernt
- M Gilså Hansen
- M Green
- M Gumbley
- M H Jeong
- M Heiman
- M Honan
- M Hudcovic
- M I Sosa Liprandi
- M Jan
- M Janion
- M Jardula
- M Kozinn
- M Krauze-Wielicka
- M L Bruno
- M Lahav
- M Lillestol
- M Mandviwala
- M Maschke
- M McCullagh
- M McKenzie
- M Micko
- M Morris
- M Muttreja
- M Nathan
- M Natour
- M O'Mahony
- M Ogorek
- M Olsen
- M Omary
- M Orlov
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- M Paiva
- M Pieniek
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- M Pini
- M Pye
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- M Richards
- M Rosenqvist
- M Rubin
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- M Santonastaso
- M Schlegl
- M Scholten
- M Schumacher
- M Shochat
- M Staab
- M Stein
- M Stoddard
- M Stribrna
- M Suwa
- M Szpajer
- M T Abola
- M Talajic
- M Teixeira
- M Tynni
- M Urina
- M Vanderheyden
- M Vatutin
- M Vejar
- M Vico
- M Vico
- M Vida
- M Vrolix
- M Wei
- M Wendland
- M West
- M Wukelic
- M Yamamoto
- M Yamashita
- M Zabel
- M Zubiate
- Marc A Pfeffer
- Marten Rosenquist
- Matyas Keltai
- McMurray J. J. V.
- Michael Hanna
- Missy Banks
- Mohan P.
- N Abelardo
- N Bedwell
- N Bogale
- N Chidambaram
- N Desai
- N Garg
- N Ghaisas
- N Gratsiansky
- N Jaffrani
- N Jaramillo
- N Koziolova
- N Mayer
- N Patterson
- N Seredyuk
- N Seshadri
- N Shilkina
- N Staxhinskiy
- N Tahirkheli
- N Vijay
- N Vita
- N Wang
- N Yarohno
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- Neville Jackson
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- P Ma
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- P Martin
- P McCullough
- P Mehta
- P Meyer
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- P O'Neill
- P Ouyang
- P P De Deyn
- P Pimentel Filho
- P Purnell
- P Qu
- P Rossi
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- P Santucci
- P Schauerte
- P Schygiel
- P Singh
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- P Wells
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- P Álvarez García
- Pais P.
- Parkhomenko A.
- Patricia Rodrigues
- Patrick Commerford
- Paul Dorian
- Pedro Barros
- Petr Jansky
- Philip Aylward
- Philippe Gabriel Steg
- Prem Pais
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- Q Lu
- Q Rizvi
- Q Y Dai
- R A Guerrero
- R Abadier
- R Acheatel
- R Ashley Jr
- R Azanero
- R B Pothineni
- R Bedoya
- R Bernstein
- R Bhargava
- R Botelho
- R Botero
- R Brat
- R Capalneanu
- R Castello
- R Chehayeb
- R Collette
- R Corbalan
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- R Foster
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- R Gopal
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- R Haberl
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- R Hart
- R Huling
- R Häge
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- R Jordan
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- R Labonte
- R Lehman
- R M Ionescu
- R MacKinnon
- R Marple
- R Mourilhe Rocha
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- R Patel
- R Pernenkil
- R S Tan
- R Sandoval
- R Schoeller
- R Senior
- R Senior
- R Shroff
- R Silverman
- R Smith
- R Swint Sr
- R Sy
- R Therrien
- R Torrijos
- R Ueda
- R Vargas
- R Vicari
- R Walsh
- R Weachter
- R Zimlichman
- Rafael Diaz
- Rafael Diaz
- Raffaele De Caterina
- Renato D Lopes
- Robert Croop
- Robert Wolf
- Robin Matthews
- Rogelio Braceras
- S Adachi
- S Andrievskaya
- S Anton
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- S Banerjee
- S Bhandari
- S Bilazarian
- S Bloom
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- S Bose
- S Connors
- S Dani
- S Ehrlich
- S Eisenberg
- S Elle
- S Fenton
- S Gass
- S Gill
- S Gips
- S Glen
- S Goldman
- S Golitsyn
- S Goto
- S Gu
- S Gupta
- S H Chu
- S Halvorsen
- S Henein
- S Husted
- S J Tahk
- S Kaatz
- S Kamakura
- S Kanorsky
- S Kent
- S Kulback
- S Leu
- S Ma
- S Nawaz
- S Novo
- S Orlando
- S Pavlyk
- S Popov
- S Potthoff
- S Potthoff
- S Promisloff
- S Ramesh
- S Roger
- S Rohrbeck
- S Rosenheck
- S Rosenthal
- S Sathe
- S Shah
- S Shalaev
- S Shustov
- S Sinha
- S Slabic
- S Sloan
- S Spitzer
- S Stamate
- S Tanaka
- S Testa
- S Tykhonova
- S U Kwon
- S Velez
- S Viskin
- S Vizel
- S Weiner
- S Wu
- S Wu
- S X Zhou
- S Yakushin
- S Yamamoto
- S Yates
- S Yogasundram
- S Yura
- S Zhao
- S Zimmermann
- Salete Nacif
- Sana Al-Khatib
- Sergei Varshavsky
- Sergey Golitsyn
- Sergio Leonardi
- Shala Ghaderi Berntsson
- Shams Zia
- Sherri Hinton
- Shinya Goto
- Steen Husted
- Stefan H Hohnloser
- Stuart Pocock
- Sumeet Subherwal
- Sunil Nepal
- Susan Mullin
- T Akihiko
- T Andersson
- T Ayres
- T Czerski
- T H Rho
- T Hayek
- T Hisaoka
- T Hoch
- T Horacek
- T Hruczkowski
- T Hu
- T Iwao
- T Iwasawa
- T J Cha
- T J Hong
- T Joen Jakobsen
- T Jääskeläinen
- T K Ong
- T Kjærnli
- T Levy
- T Murakami
- T Nanea
- T Nielsen
- T Novikova
- T Omland
- T Pasierski
- T Rebane
- T Saito
- T Sasaki
- T Segura
- T Shinozaki
- T Sotnikova
- T Tobin
- T Treshkur
- T Trouton
- T Vidic
- T Yamada
- T Zhelninova
- Tony Dremsizov
- U Thadani
- Uri Flato
- V Arkhipov
- V Bertomeu
- V Dedek
- V Desai
- V Eltishcheva
- V Jain
- V K Puri
- V Kostenko
- V Lesnov
- V Mareev
- V Medrano
- V Nadar
- V Netiazhenko
- V Nguyen
- V Oleynikov
- V Orlov
- V P Harjola
- V S Prakash
- V Srikanthan
- V Sulimov
- V Tashchuk
- V Terekhov
- V Tseluyko
- V Vizir
- V Volkov
- V Yakusevich
- V Zadionchenko
- Veli Pekka Harjola
- Verheugt F. W. A.
- W Bowden
- W Cabrera
- W Haught
- W Haverkamp
- W Heddle
- W Henry 3rd
- W Herzog
- W Jaffrani
- W Kufs
- W Li
- W Phillips
- W Piotrowski
- W Ridsdill Smith
- W Rieker
- W Ruzyllo
- W Smith
- W Tracz
- W Wilson
- W Zonggui
- Wallentin L. Collaborators ARISTOTLE Committees and Investigators: Christopher B Granger
- Witold Ruzyllo
- X Albert
- X Chen
- X Jiang
- X Wang
- X Yang
- Y Atsushi
- Y Burmak
- Y Chandrashekhar
- Y Chen
- Y Cohen
- Y Higashi
- Y K Chan
- Y K Wong
- Y Karpov
- Y Kawase
- Y Kobayashi
- Y Koretsune
- Y Mostovoy
- Y N Kim
- Y Nakamura
- Y Pozdnyakov
- Y Sato
- Y Shubik
- Y Tsubokou
- Y Turgeman
- Y Yin
- Y Zhang
- Z Kiedrowicz
- Z László
- Z Meneghelo
- Z Q Li
- Z Sizova
- Z Telyatnikova
- Z Yousef
- Z Yousef
- Z Yusof
- Zhu J.
- Zubin Eapen
- Á Illés
- Publication venue
- 'Massachusetts Medical Society'
- Publication date
- 01/01/2011
- Field of study
BACKGROUND: Vitamin K antagonists are highly effective in preventing stroke in patients with atrial fibrillation but have several limitations. Apixaban is a novel oral direct factor Xa inhibitor that has been shown to reduce the risk of stroke in a similar population in comparison with aspirin. METHODS: In this randomized, double-blind trial, we compared apixaban (at a dose of 5 mg twice daily) with warfarin (target international normalized ratio, 2.0 to 3.0) in 18,201 patients with atrial fibrillation and at least one additional risk factor for stroke. The primary outcome was ischemic or hemorrhagic stroke or systemic embolism. The trial was designed to test for noninferiority, with key secondary objectives of testing for superiority with respect to the primary outcome and to the rates of major bleeding and death from any cause. RESULTS: The median duration of follow-up was 1.8 years. The rate of the primary outcome was 1.27% per year in the apixaban group, as compared with 1.60% per year in the warfarin group (hazard ratio with apixaban, 0.79; 95% confidence interval [CI], 0.66 to 0.95; P<0.001 for noninferiority; P = 0.01 for superiority). The rate of major bleeding was 2.13% per year in the apixaban group, as compared with 3.09% per year in the warfarin group (hazard ratio, 0.69; 95% CI, 0.60 to 0.80; P<0.001), and the rates of death from any cause were 3.52% and 3.94%, respectively (hazard ratio, 0.89; 95% CI, 0.80 to 0.99; P = 0.047). The rate of hemorrhagic stroke was 0.24% per year in the apixaban group, as compared with 0.47% per year in the warfarin group (hazard ratio, 0.51; 95% CI, 0.35 to 0.75; P<0.001), and the rate of ischemic or uncertain type of stroke was 0.97% per year in the apixaban group and 1.05% per year in the warfarin group (hazard ratio, 0.92; 95% CI, 0.74 to 1.13; P = 0.42). CONCLUSIONS: In patients with atrial fibrillation, apixaban was superior to warfarin in preventing stroke or systemic embolism, caused less bleeding, and resulted in lower mortality. Copyright © 2011 Massachusetts Medical Society. All rights reserved
Apixaban compared with warfarin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: A subgroup analysis of the ARISTOTLE trial
- Author
- A Agarwal
- A Ahsan
- A Ajala
- A Al-Mudamgha
- A Alexander
- A Alfieri
- A Alings
- A Alwail
- A Bakhai
- A Barsotti
- A Bartkowiak
- A Bauer
- A Bazylevych
- A Bazzi
- A Bethencourt González
- A Bharani
- A Bittersohl
- A Boruczkowska-Kaszkowiak
- A Boyle
- A Bragina
- A Bredero
- A Brockmyre
- A Budaj
- A Buxton
- A Caccavo
- A Cassettari
- A Chhabra
- A Chmielinski
- A Cohen
- A Cooke
- A Cziraki
- A D'Angelo
- A De Paola
- A Dharmadhikari
- A Dowell
- A Francis
- A Gabito
- A Galicia
- A Ghirarduzzi
- A Golovach
- A Gordienko
- A Govorin
- A Hamad
- A Hershson
- A Hetzel
- A Hrabar
- A Ivleva
- A Jacob
- A Jones
- A Kabour
- A Kastanayan
- A Katona
- A Kelly
- A Koniakhin
- A Kovács
- A Lebowitz
- A Levin
- A Liu
- A Lorga Filho
- A Lowy
- A MacKinnon
- A Magnano
- A Marmor
- A Matsushima
- A Meholick
- A Mirode
- A Mohácsi
- A Moriarty
- A Muniz
- A Mügge
- A Mügge
- A Naik
- A Nambiar
- A Obrezan
- A Ocicka-Kozakiewicz
- A Pandey
- A Papp
- A Parkhomenko
- A Patel
- A Peeters
- A Pálinkás
- A Quick
- A Rabelo Alves Jr
- A Reyes
- A Rodriguez
- A Roman
- A Rubin
- A Salacata
- A Salajan
- A Samal
- A Sanchez
- A Schaap
- A Sinopalnikov
- A Skolnick
- A Solomon
- A Svistov
- A Ugarriza
- A Utech
- A Vértes
- A Wade
- A Warner
- A Weiss
- A Wellford
- A Yagensky
- Aldo Maggione
- Alexander J. H.
- Alexander Parkhomenko
- Ali Zomorodi
- Alings M.
- Alvaro Albrecht
- Alvaro Avezum
- Andreas Terent
- Anna Stenborg
- Antonio Carlos Lopes
- Antonio G Hermosillo
- Antonio M W Alings
- Axel Akerblom
- B Bachhuber
- B Beanblossom
- B Blue
- B Bruneel
- B Bryhni
- B Coutu
- B Garbelini Jr
- B Gervais
- B Gorenek
- B Griewing
- B H Oh
- B Hattler
- B Iteld
- B Jackson
- B Kowalski
- B Lachterman
- B Lasko
- B Lewis
- B Malipeddi
- B McClements
- B Peart
- B Pieske
- B Platt
- B Podogrodzka
- B Ramagiri
- B Ramjattan
- B Schifferdecker
- B Sidorenko
- B Srinivasasastry
- B Stockins
- B Winkelmann
- B Wollaert
- B Yu
- B Øie
- Bahit M. C.
- Basil S Lewis
- Bernard J Gersh
- Bradley Kolls
- Byung-Hee Oh
- C Arean Martinez
- C Arsenescu Georgescu
- C Beneitez
- C Bredlau
- C Calvo Vargas
- C Chavez
- C Christersson
- C Corder
- C Cuneo
- C D Tseng
- C Dézsi
- C East
- C Erol
- C Fortin
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- C Hassel
- C Höglund
- C J Lindholm
- C JerJes-Sanchez
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- C Lovell
- C Massey
- C McPherson
- C Mihaela Tanaseanu
- C Muratore
- C Olivieri
- C Pincetti
- C Pop
- C Powers
- C Poy
- C Raffo
- C Riojas
- C Rios Vasquez
- C Rodriguez-Fierro
- C Russo
- C Sofley
- C Sotolongo
- C Toftager Larsen
- C Torp-Pedersen
- C Tuxen
- C Van der Zwaan
- C W Lee
- C Weimar
- C Y Rhim
- C Yu
- C Zaidman
- Carlo Lombardi
- Cetin Erol
- Cheryl Bushnell
- Christoph Varenhorst
- Claes Held
- D Agarwal
- D Albuquerque
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- Diener H. -C. ARISTOTLE Committees and Investigators: Christopher B Granger
- Dipen Parikh
- Dragos Vinereanu
- E Ball
- E Blumberg
- E Carasca
- E Engeron
- E Flores
- E Galve
- E Gomez
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- E Klainman
- E Kosinski
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- E Manenti
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- E Pelloso
- E Privalova
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- E Richiardi
- E Rivera
- E Sabbah
- E Schwarz
- E Sivkova
- E Suprun.
- E van Nieuwenhuizen
- E von Hodenberg
- E Zemtsovsky
- E Zidkova
- Easton J. D.
- Elaine M Hylek
- Elaine M Hylek
- Emil Hagstrom
- Erik Lundstrom
- F Agnone
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- F Al-Khalili
- F Albrecht
- F Bai
- F Collado
- F Collado
- F De Leon
- F de Looze
- F de Looze
- F de Looze
- F de Looze
- F Dunn
- F Grondin
- F Kouichi
- F Lakatos
- F Maislos
- F Medina
- F Olías de la Cruz
- F Provenier
- F Rolandi
- F Schlachetzki
- F St Maurice
- F Stockenhuber
- F Stögbauer
- F Verheugt
- F Villaça Guimaraes Filho
- F Zhang
- Fernando Lanas
- Freek W A Verheugt
- G Andrei Dan
- G Arutyunov
- G Aycock
- G Boxho
- G Brooks
- G Bustamante
- G Casolo
- G Dzyak
- G Feldman
- G Filonenko
- G Ford
- G Gojanur
- G Hanovich
- G Ignatenko
- G Jensen
- G Kahrmann
- G Kamalov
- G Kania
- G Lavabre
- G Lip
- G Lu
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- G McInnes
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- G Sosa-Suarez
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- G Syan
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- Greg Stashenko
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- W Zonggui
- Wallentin L.
- Witold Ruzyllo
- Wojdyla D. M.
- X Albert
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- X Yang
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- Y Sato
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- Y Turgeman
- Y Yin
- Y Zhang
- Z Kiedrowicz
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- Z Meneghelo
- Z Q Li
- Z Sizova
- Z Telyatnikova
- Z Yousef
- Z Yousef
- Z Yusof
- Zubin Eapen
- Á Illés
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2012
- Field of study
Background: In the ARISTOTLE trial, the rate of stroke or systemic embolism was reduced by apixaban compared with warfarin in patients with atrial fibrillation (AF). Patients with AF and previous stroke or transient ischaemic attack (TIA) have a high risk of stroke. We therefore aimed to assess the efficacy and safety of apixaban compared with warfarin in prespecified subgroups of patients with and without previous stroke or TIA. Methods: Between Dec 19, 2006, and April 2, 2010, patients were enrolled in the ARISTOTLE trial at 1034 clinical sites in 39 countries. 18 201 patients with AF or atrial flutter were randomly assigned to receive apixaban 5 mg twice daily or warfarin (target international normalised ratio 2·0-3·0). The median duration of follow-up was 1·8 years (IQR 1·4-2·3). The primary efficacy outcome was stroke or systemic embolism, analysed by intention to treat. The primary safety outcome was major bleeding in the on-treatment population. All participants, investigators, and sponsors were masked to treatment assignments. In this subgroup analysis, we estimated event rates and used Cox models to compare outcomes in patients with and without previous stroke or TIA. The ARISTOTLE trial is registered with ClinicalTrials.gov, number NTC00412984. Findings: Of the trial population, 3436 (19%) had a previous stroke or TIA. In the subgroup of patients with previous stroke or TIA, the rate of stroke or systemic embolism was 2·46 per 100 patient-years of follow-up in the apixaban group and 3·24 in the warfarin group (hazard ratio [HR] 0·76, 95% CI 0·56 to 1·03); in the subgroup of patients without previous stroke or TIA, the rate of stroke or systemic embolism was 1·01 per 100 patient-years of follow-up with apixaban and 1·23 with warfarin (HR 0·82, 95% CI 0·65 to 1·03; p for interaction=0·71). The absolute reduction in the rate of stroke and systemic embolism with apixaban versus warfarin was 0·77 per 100 patient-years of follow-up (95% CI -0·08 to 1·63) in patients with and 0·22 (-0·03 to 0·47) in those without previous stroke or TIA. The difference in major bleeding with apixaban compared with warfarin was 1·07 per 100 patient-years (95% CI 0·09-2·04) in patients with and 0·93 (0·54-1·32) in those without previous stroke or TIA. Interpretation: The effects of apixaban versus warfarin were consistent in patients with AF with and without previous stroke or TIA. Owing to the higher risk of these outcomes in patients with previous stroke or TIA, the absolute benefits of apixaban might be greater in this population. Funding: Bristol-Myers Squibb and Pfizer. © 2012 Elsevier Ltd