Pengendali Motor Induksi 1 Fasa Dengan Metode PWM Sinusoida Berbasis Mikrokontroler 68HC11

Pada pengendalian motor induksi yang dilakukan secara konvensional tidak diperoleh pengaturan yang kontinyu dan linier, sehingga perlu dilakukan penelitian tentang pengendalian motor induksi dengan teknik inverter. Penelitian ini bertujuan melakukan pengembangan dan evaluasi unjuk kerja pengendalian motor induksi satu fasa dengan metode PWM sunusoida berbasis mikrokontroler. Pengendalian menggunakan rangkaian jembatan inverter jenis PWMVSI (DC-Link inverter) dengan teknik modulasi PWM menggunakan mikrokontroler 68HC11E9, dan diharapkan dapat menggerakkan motor induksi pada kecepatan yang berbeda-beda. Pada penelitian ini digunakan motor induksi satu fasa Z-406, 220 Volt, 50-60 Hz, 125W. Penelitian dimulai dengan pembuatan perangkat keras berupa inverter menggunakan MOSFET sebagai komponen pensaklaran dan diteruskan dengan menyusun rangkaian penggerak inverter satu fasa. Pola sinyal PWM sinusoida dibentuk dengan teknik perhitungan lima modulasi PWM yang berbeda. Dari pola gelombang tersebut dibuat program pembangkit pulsa PWM satu fasa dan perangkat pendukungnya. Selanjutnya dilakukan pengamatan bentuk gelombang PWM keluaran MCU, tegangan, arus keluaran inverter dan mengukur kecepatan putar motor untuk lima indeks modulasi, yaitu (1), (0,81), (0,59), (0,37), dan (0,15). Hasil penelitian menunjukkan bahwa pengaturan kecepatan putar motor induksi untuk frekuensi tetap 50 Hz dengan 5 indeks modulasi berbeda dengan metode PWM sinusoida berbasis mikrokontroler dapat menghasilkan putaran motor yang bervariasi

Transect width and missed observations in counting muskoxen (Ovibos moschatus) from fixed-wing aircraft

While conductioning muskox-censuses (Ovibos moschatus) in winter in Jameson Land, NE Greenland, from a fixed-wing aircraft, we examined the width of transects covered. We used a laser range-finder binocular for measuring the distance to observed groups. We found that 1000 m was a reasonable limit for observing a high proportion of the muskoxen present even though it was possible to observe muskoxen from 4000 m or even more. Using two observers on the right side of the aircraft each speaking into a tape recorder with an automatic time signal, we recorded observations and performed a double-observer experiment. By matching the group sizes and perpendicular distances with times of observation we could compare observations of the two observers. We found that both observers missed up to 25% of muskoxen within a 2000 m transect width. The main reasons for missing animals is difficulty in obtaining reference points in snow covered landscape and fatigue of the observers. Calibration of estimated distances using read-outs from the laser-range finder is an adequate method of obtaining distance data for line transect calculations. Our double-observer experiment demonstrated that even groups close to the transect are easily missed

Systematic characterization of deubiquitylating enzymes for roles in maintaining genome integrity.

DNA double-strand breaks (DSBs) are perhaps the most toxic of all DNA lesions, with defects in the DNA-damage response to DSBs being associated with various human diseases. Although it is known that DSB repair pathways are tightly regulated by ubiquitylation, we do not yet have a comprehensive understanding of how deubiquitylating enzymes (DUBs) function in DSB responses. Here, by carrying out a multidimensional screening strategy for human DUBs, we identify several with hitherto unknown links to DSB repair, the G2/M DNA-damage checkpoint and genome-integrity maintenance. Phylogenetic analyses reveal functional clustering within certain DUB subgroups, suggesting evolutionally conserved functions and/or related modes of action. Furthermore, we establish that the DUB UCHL5 regulates DSB resection and repair by homologous recombination through protecting its interactor, NFRKB, from degradation. Collectively, our findings extend the list of DUBs promoting the maintenance of genome integrity, and highlight their potential as therapeutic targets for cancer.This is the author's accepted manuscript. The final version is available from Nature Publishing Group via http://dx.doi.org/10.1038/ncb302

Stable isotope signatures of Holocene syngenetic permafrost trace seabird presence in the Thule District (NW Greenland)

Holocene permafrost from ice wedge polygons in the vicinity of large seabird breeding colonies in the Thule District, NW Greenland, was drilled to explore the relation between permafrost aggradation and seabird presence. The latter is reliant on the presence of the North Water Polynya (NOW) in the northern Baffin Bay. The onset of peat accumulation associated with the arrival of little auks (Alle alle) in a breeding colony at Annikitisoq, north of Cape York, is radiocarbon-dated to 4400 cal BP. A thick-billed murre (Uria lomvia) colony on Appat (Saunders Island) in the mouth of the Wolstenholme Fjord started 5650 cal BP. Both species provide marine-derived nutrients (MDNs) that fertilize vegetation and promote peat growth. The geochemical signature of organic matter left by the birds is traceable in the frozen Holocene peat. The peat accumulation rates at both sites are highest after the onset, decrease over time, and were about 2-times faster at the little auk site than at the thick-billed murre site. High accumulation rates induce shorter periods of organic matter (OM) decomposition before it enters the perennially frozen state. This is seen in comparably high C=N ratios and less depleted 13C, pointing to a lower degree of OM decomposition at the little auk site, while the opposite pattern can be discerned at the thick-billed murre site. Peat accumulation rates correspond to 15N trends, where decreasing accumulation led to increasing depletion in 15N as seen in the little-auk-related data. In contrast, the more decomposed OM of the thick-billed murre site shows almost stable 15N. Late Holocene wedge ice fed by cold season precipitation was studied at the little auk site and provides the first stable-water isotopic record from Greenland with mean 18O of 8:00:8, mean D of 36:25:7, mean d excess of 7:70:7, and a 18O-D slope of 7.27, which is close to those of the modern Thule meteoric water line. The syngenetic ice wedge polygon development is mirrored in testacean records of the little auk site and delineates polygon low-center, dry-out, and polygon-high-center stages. The syngenetic permafrost formation directly depending on peat growth (controlled by bird activity) falls within the period of neoglacial cooling and the establishment of the NOW, thus indirectly following the Holocene climate trends

Loss of life years after a hip fracture: Effects of age and sex

Background Patients with a hip fracture have a high mortality; however, it is not clear how large the loss of life-years is over an extended observation period

Importance of basophil activation testing in insect venom allergy

<p>Abstract</p> <p>Background</p> <p>Venom immunotherapy (VIT) is the only effective treatment for prevention of serious allergic reactions to bee and wasp stings in sensitized individuals. However, there are still many questions and controversies regarding immunotherapy, like selection of the appropriate allergen, safety and long term efficacy.</p> <p>Methods</p> <p>Literature review was performed to address the role of basophil activation test (BAT) in diagnosis of venom allergy.</p> <p>Results</p> <p>In patients with positive skin tests or specific IgE to both honeybee and wasp venom, IgE inhibition test can identify sensitizing allergen only in around 15% and basophil activation test increases the identification rate to around one third of double positive patients. BAT is also diagnostic in majority of patients with systemic reactions after insect stings and no detectable IgE. High basophil sensitivity to allergen is associated with a risk of side effects during VIT. Persistence of high basophil sensitivity also predicts a treatment failure of VIT.</p> <p>Conclusion</p> <p>BAT is a useful tool for better selection of allergen for immunotherapy, for identification of patients prone to side effects and patients who might be treatment failures. However, long term studies are needed to evaluate the accuracy of the test.</p