The supramolecular arrangement in the Ni(II) complexes of isothiosemicarbazide

The molecules of two complexes [Ni(ITSC)2(H2O)2](tere)·2H2O and [Ni(ITSC)2(NO3)2] (ITSC = S-methylisothiosemicarbazide; tere = terephthalate) tend to associate trough the hydrogen bonding interactions into the characteristic 2D blocks separated by the S-methyl moieties. The different coordination mode of the isothiosemicarbazide comparing to thiosemicarbazide (TSC) prevents the formation of the complementary hydrogen bonds with dicarboxylate important for selfassambly of TSC complexes, however in these ITSC the terephthalate anion has role in connection of the blocks and transformation of the 2D into the 3D supramolecular structure. The similar crystal arrangement is found in two earlier reported complexes of Ni(II) with ITSC.Physical chemistry 2004 : 7th international conference on fundamental and applied aspects of physical chemistry; Belgrade (Serbia); 21-23 September 200

Crystal and absolute structure of the aquadichloro(pyridoxal thiosemicarbazone) iron(III) chloride

A new Fe(III) complex of pyridoxal thiosemicarbazone (H2L) has been characterized by single-crystal X-ray analysis. The Fe atom in the title complex, [Fe(H2L)Cl2(H2O)]Cl, has a distorted octahedral configuration formed by NSO2Cl2 donor set. Six-membered chelate ring significantly deviates from planar form. The crystal structure is stabilized by weak intermolecular C-H…π interaction directed towards the center of the pyridine ring.Physical chemistry 2004 : 7th international conference on fundamental and applied aspects of physical chemistry; Belgrade (Serbia); 21-23 September 200

Metal complexes with Schiff-base ligands - pyridoxal and semicarbazide-based derivatives

The most important results of extensive studies (syntheses, spectral, magnetic, voltammetric and structural characteristics and biological activity) of metal complexes with pyridoxal semi-, thiosemi- and isothiosemicarbazones are reviewed

Transition metal complexes with thiosemicarbazide-based ligands. Part 60. Reactions of copper(II) bromide with pyridoxal S-methylisothiosemicarbazone (PLITSC). Crystal structure of [Cu(PLITSC−H)H2O]Br•H2O

The synthesis and structural characterization of a square-planar copper(II) complex with pyridoxal S-methylisothiosemicarbazone (PLITSC) of the formula [Cu(PLITSC−H)H2O]Br•H2O (1) as the first Cu(II) complex with monoanionic form of this ligand were described. Complex 1 together with two previously synthesized complexes [Cu(PLITSC)Br2] (2) and [Cu(PLITSC)Br(MeOH)]Br (3) were characterized by elemental analysis, IR and electronic spectra and also by the methods of thermal analysis, conductometry and magnetochemistry. [Projekat Pokrajisnkog sekretarijata za nauku i tehnoloski razvoj Vojvodine i Ministarstva nauke Republike Srbije, br. 172014

Transition metal complexes with pyrazole-based ligands. Part 29. Reactions of zinc(II) and mercury(II) thiocyanate with 4-acetyl-3-amino-5-methylpyrazole

The work is concerned with the crystal and molecular structures of zinc(II) and mercury(II) complexes with 4-acetyl-3-amino-5-methylpyrazole (aamp) of the coordination formulae [Zn(NCS)(2)(aaMP)(2)] and (HaaMP)(2)[Hg(SCN)(4)]. The zinc(II) complex was obtained by the reaction of a warm methanolic solution of aamp with a mixture of zinc(II) nitrate and ammonium thiocyanate, whereas the mercury(II) complex was prepared by the reaction of a warm methanolic solution of aamp and a warm, slightly acidified aqueous solution of [Hg(SCN)(4)](2-). Both complexes have a tetrahedral geometry, which in the case of zinc complex is formed by monodentate coordination of two aamp molecules and two isothiocyanate groups. The Zn(II) and Hg(II) atoms have significantly deformed coordination geometry. In both crystal structures the pyrazole derivative has a planar form, probably stabilized by an intramolecular N-H center dot center dot center dot O hydrogen bond. Apart from the X-ray structural analysis, the isolated complexes were characterized by elemental analysis, IR spectroscopy, conductometric measurements and thermal analysis

Crystal structure of dicholoro-(3,5-dimethyl-1H-pyrazole-1-carboxamidine-N,N )copper(II), Cu(C6H10N4)Cl-2

C6H10Cl2CuN4, monoclinic, P2(1)/n (no. 14), a = 7.316(2) angstrom b = 16.002(2) angstrom, c = 9.202(6) angstrom, beta = 113.15 (2)degrees, V = 990.6 angstrom(3), Z = 4, R-gt(F) = 0.054, wR(ref)(F-2) = 0.125, T = 293 K

Crystal structure of chlorido-tris(3-amino-5-phenyl-1H-pyrazole-N-2)zinc(II) chloride, [ZnCl(C9H9N3)(3)]Cl

C27H27Cl2N9Zn, tetragonal, P (4) over bar2(1)c (no. 114), a = 17.522(2) angstrom, C = 18.583(3) angstrom, V= 5705.4 angstrom(3), Z = 8, R-gt(F) = 0.040, wR(ref)(F-2) = 0.114, T = 293 K

Cytotoxic activities of new iron(III) and nickel(II) chelates of some S-methyl-thiosemicarbazones on K562 and ECV304 cells

The S-methyl-thiosemicarbazones of the 2- hydroxy-R-benzaldehyde (R= H, 3-OH 3-OCH3 or 4-OCH3) reacted with the corresponding aldehydes in the presence of FeCl3 and NiCl2. New ONNO chelates of iron(III) and nickel (II) with hydroxy- or methoxy-substitued N1,N4-diarylidene-Smethyl- thiosemicarbazones were characterized by means of elemental analysis, conductivity and magnetic measurements, UV-Vis, IR and 1H-NMR spectroscopies. Cytotoxic activities of the compounds were determined using K562 chronic myeloid leukemia and ECV304 human endothelial cell lines by MTT assay. It was determined that monochloro N1-4- methoxysalicylidene-N4-4-methoxysalicylidene-S-methylthiosemicarbazidato- iron(III) complex showed selective anti-leukemic effects in K562 cells while has no effect in ECV304 cells in the 0.53 μg/ml (IC50) concentrations. Also, some methoxy-substitued nickel(II) chelates exhibit high cytotoxic activitiy against both of these cell lines in low concentrations. Cytotoxicity data were evaluated depending on cell lines origin and position of the substituents on aromatic rings

Transition metal complexes with pyrazole-based ligands. XXII. Di-mu-thiocyanato-bis[(3,5-dimethyl-1H-pyrazole-1-carboxamidine-kappa N-2,N )(thiocyanato-kappa N)copper(II)] and a redetermination of bis(3,5-dimethyl-1H-pyrazole-1-carboxamidine-kappa N-2,N )bis(nitrato-kappa O)-copper(II)

The title Cu-II complex, [Cu-2(NCS)(4)(C6H10N4)(2)], represents the first crystal structure of a polynuclear transition metal complex with the 3,5-dimethyl-1H-pyrazole-1-carboxamidine ligand (HL). It is compared with previously reported crystal structures of metal complexes with the same HL ligand. The molecule contains an eight-membered binuclear Cu-2(NCS)(2) ring, which is centrosymmetric and in a chair conformation. The Cu atom has a distorted square-pyramidal geometry with a very elongated Cu-S bond of 2.993 (2) angstrom. The crystal structure redetermination of the bis(3,5-dimethyl-1H-pyrazole-1-carboxamidine-kappa(2)N,N) bis(nitrato-kappa O) copper(II) complex, [Cu(NO3)(2)(C6H10N4)(2)], and analysis of its hydrogen bonds confirm the significance of the NO3 groups in the formation of a three-dimensional hydrogen-bonding network. Both complexes are centrosymmetric, the inversion centre being located at the mid-point of the Cu center dot center dot center dot Cu line in (I) and the Cu atom being located at the inversion centre in (II)