907 research outputs found

    Evaluating the use of alternative normalization approaches on SARS-CoV-2 concentrations in wastewater: experiences from two catchments in northern Sweden

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    The detection of SARS-CoV-2 RNA fragments in feces has paved the way for wastewater-based epidemiology to contribute to COVID-19 mitigation measures, with its use in a public health context still under development. As a way to facilitate data comparison, this paper explores the impact of using alternative normalization approaches (wastewater treatment plant (WWTP) flow, population size estimates (derived using total nitrogen (TN), total phosphorus (TP) and census data) and pepper mild mottle virus (PMMoV)) on the relationship between viral wastewater data and clinical case numbers. Influent wastewater samples were collected at two WWTPs in Luleå, northern Sweden, between January and March 2021. TN and TP were determined upon sample collection, with RNA analysis undertaken on samples after one freeze–thaw cycle. The strength of the correlation between normalization approaches and clinical cases differed between WWTPs (r ≤ 0.73 or r ≥ 0.78 at the larger WWTP and r ≤ 0.23 or r ≥ 0.43 at the smaller WWTP), indicating that the use of wastewater as an epidemiological tool is context-dependent. Depending on the normalization approach utilized, time-shifted analyses imply that wastewater data on SARS-CoV-2 RNA pre-dated a rise in clinical cases by 0–2 and 5–8 days, for the lager and smaller WWTPs, respectively. SARS-CoV-2 viral loads normalized to the population or PMMoV better reflect the number of clinical cases when comparing wastewater data between sewer catchments

    Systematic Review of Preclinical Surgical Meshes for Hernia Repair

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    Hernia repair is one of the most common procedures performed around the world. Surgical mesh materials are used to reinforce hernia repairs and improve surgical outcomes. However, current commercial mesh materials produce problems such as infection, rejection, shrinkage, adhesion, and mechanical failure. These problems contribute to a high rate of hernia recurrence and mesh removal. With the number of hernias expected to rise in the future due to increases in obesity and diabetes, the need for more effective mesh materials is critical. This review aims to identify, evaluate, and summarize experimental surgical mesh materials used in the preclinical stages of development and catalogue their characteristics and the tests used for their evaluation.https://digitalcommons.unmc.edu/surp2021/1053/thumbnail.jp

    Invest to Save: Report and Recommendations of the NSF-DELOS Working Group on Digital Archiving and Preservation

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    Digital archiving and preservation are important areas for research and development, but there is no agreed upon set of priorities or coherent plan for research in this area. Research projects in this area tend to be small and driven by particular institutional problems or concerns. As a consequence, proposed solutions from experimental projects and prototypes tend not to scale to millions of digital objects, nor do the results from disparate projects readily build on each other. It is also unclear whether it is worthwhile to seek general solutions or whether different strategies are needed for different types of digital objects and collections. The lack of coordination in both research and development means that there are some areas where researchers are reinventing the wheel while other areas are neglected. Digital archiving and preservation is an area that will benefit from an exercise in analysis, priority setting, and planning for future research. The WG aims to survey current research activities, identify gaps, and develop a white paper proposing future research directions in the area of digital preservation. Some of the potential areas for research include repository architectures and inter-operability among digital archives; automated tools for capture, ingest, and normalization of digital objects; and harmonization of preservation formats and metadata. There can also be opportunities for development of commercial products in the areas of mass storage systems, repositories and repository management systems, and data management software and tools.

    SI 655 - Management of Electronic Records, Winter 2009

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    Records are the corporate and cultural memory that provide proof of actions and decisions, build a knowledge-base for reflection and learning, and form a perspective on today's society that we will pass on to future generations. As organizations create and maintain more of their records electronically, they are struggling to develop effective policies, systems, and practices to capture, maintain, and preserve electronic records.This course examines the ways in which new information technologies challenge organizations' capacities to define, identify, control, manage, and preserve electronic records. Students learn how different organizational, technological, regulatory, and cultural factors affect the strategies, practices, and tools that organizations can employ to manage electronic records. Problems of long-term preservation and continuing access to electronic records are analyzed and addressed. Addresses electronic records management issues in a wide variety of settings, including archives and manuscript repositories.http://deepblue.lib.umich.edu/bitstream/2027.42/78185/5/wallace-hedstrom-si655-winter09-lectures-week11.odphttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/6/wallace-hedstrom-si655-winter09-lectures-week9.odphttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/7/wallace-hedstrom-si655-winter09-lectures-week9.ppthttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/8/Wallace-Hedstrom-SI655-Winter09-Lectures-Week6.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/9/Wallace-Hedstrom-SI655-Winter09-Lectures-Week7.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/10/Wallace-Hedstrom-SI655-Winter09-Lectures-Week10.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/11/wallace-hedstrom-si655-winter09-lectures-week3.odphttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/12/wallace-hedstrom-si655-winter09-lectures-week5.odphttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/13/wallace-hedstrom-si655-winter09-lectures-week10.ppthttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/14/wallace-hedstrom-si655-winter09-lectures-week6.odphttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/15/Wallace-Hedstrom-SI655-Winter09-Lectures-Week4.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/16/Wallace-Hedstrom-SI655-Winter09-Lectures-Week13.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/17/wallace-hedstrom-si655-winter09-lectures-week2.odphttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/18/Wallace-Hedstrom-SI655-Winter09-Lectures-Week3.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/19/wallace-hedstrom-si655-winter09-lectures-week4.odphttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/20/wallace-hedstrom-si655-winter09-lectures-week13.ppthttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/21/wallace-hedstrom-si655-winter09-lectures-week1.odphttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/22/wallace-hedstrom-si655-winter09-lectures-week10.odphttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/23/Wallace-Hedstrom-SI655-Winter09-Lectures-Week11.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/24/Wallace-Hedstrom-SI655-Winter09-Lectures-Week12.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/25/wallace-hedstrom-si655-winter09-lectures-week1.ppthttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/26/wallace-hedstrom-si655-winter09-lectures-week6.ppthttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/27/wallace-hedstrom-si655-winter09-lectures-week12.ppthttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/28/wallace-hedstrom-si655-winter09-lectures-week13.odphttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/29/wallace-hedstrom-si655-winter09-lectures-week9_0.odphttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/30/wallace-hedstrom-si655-winter09-lectures-week2.ppthttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/31/wallace-hedstrom-si655-winter09-lectures-week3.ppthttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/32/Wallace-Hedstrom-SI655-Winter09-Lectures-Week1.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/33/wallace-hedstrom-si655-winter09-lectures-week9_0.ppthttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/34/wallace-hedstrom-si655-winter09-lectures-week4.ppthttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/35/Wallace-Hedstrom-SI655-Winter09-Lectures-Week2.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/36/Wallace-Hedstrom-SI655-Winter09-Lectures-Week8.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/37/Wallace-Hedstrom-SI655-Winter09-Lectures-Week9.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/38/wallace-hedstrom-si655-winter09-lectures-week11.ppthttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/39/wallace-hedstrom-si655-winter09-lectures-week12.odphttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/40/wallace-hedstrom-si655-winter09-lectures-week7.odphttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/41/Wallace-Hedstrom-SI655-Winter09-Lectures-Week5.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/42/wallace-hedstrom-si655-winter09-lectures-week5.ppthttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/43/wallace-hedstrom-si655-winter09-lectures-week7.ppthttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/44/wallace-hedstrom-si655-winter09-syllabus.odthttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/45/wallace-hedstrom-si655-winter09-syllabus.dochttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/46/wallace-hedstrom-si655-winter09-syllabus.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/78185/47/si655-winter2009.zi

    Estimates in Beurling--Helson type theorems. Multidimensional case

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    We consider the spaces Ap(Tm)A_p(\mathbb T^m) of functions ff on the mm -dimensional torus Tm\mathbb T^m such that the sequence of the Fourier coefficients f^={f^(k), k∈Zm}\hat{f}=\{\hat{f}(k), ~k \in \mathbb Z^m\} belongs to lp(Zm), 1≤p<2l^p(\mathbb Z^m), ~1\leq p<2. The norm on Ap(Tm)A_p(\mathbb T^m) is defined by ∥f∥Ap(Tm)=∥f^∥lp(Zm)\|f\|_{A_p(\mathbb T^m)}=\|\hat{f}\|_{l^p(\mathbb Z^m)}. We study the rate of growth of the norms ∥eiλφ∥Ap(Tm)\|e^{i\lambda\varphi}\|_{A_p(\mathbb T^m)} as ∣λ∣→∞, λ∈R,|\lambda|\rightarrow \infty, ~\lambda\in\mathbb R, for C1C^1 -smooth real functions φ\varphi on Tm\mathbb T^m (the one-dimensional case was investigated by the author earlier). The lower estimates that we obtain have direct analogues for the spaces Ap(Rm)A_p(\mathbb R^m)

    Models for subsurface drainage

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    April 1971.Bibliography: pages 28-30.supported by the Inland Waters Directorate, Canada Department of Environment, and the U.S. National Science Foundation, Grant GK-31521 X

    Atmospheric conditions and their effect on ball-milled magnesium diboride

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    Magnesium diboride bulk pellets were fabricated from pre-reacted MgB2 powder ball milled with different amounts of exposure to air. Evidence of increased electron scattering including increased resistivity, depressed Tc, and enhanced Hc2 of the milled and heat treated samples were observed as a result of increased contact with air. These and other data were consistent with alloying with carbon as a result of exposure to air. A less clear trend of decreased connectivity associated with air exposure was also observed. In making the case that exposure to air should be considered a doping process, these results may explain the wide varibability of "undoped" MgB2 properties extant in the literature.Comment: Work presented at ASC 2006 in Seattl
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