Correlation of velocity and susceptibility in patients with aneurysmal subarachnoid hemorrhage

In many cerebral grey matter structures including the neocortex, spreading depolarization (SD) is the principal mechanism of the near-complete breakdown of the transcellular ion gradients with abrupt water influx into neurons. Accordingly, SDs are abundantly recorded in patients with traumatic brain injury, spontaneous intracerebral hemorrhage, aneurysmal subarachnoid hemorrhage (aSAH) and malignant hemispheric stroke using subdural electrode strips. SD is observed as a large slow potential change, spreading in the cortex at velocities between 2 and 9 mm/min. Velocity and SD susceptibility typically correlate positively in various animal models. In patients monitored in neurocritical care, the Co-Operative Studies on Brain Injury Depolarizations (COSBID) recommends several variables to quantify SD occurrence and susceptibility, although accurate measures of SD velocity have not been possible. Therefore, we developed an algorithm to estimate SD velocities based on reconstructing SD trajectories of the wave-front's curvature center from magnetic resonance imaging scans and time-of-SD-arrival- differences between subdural electrode pairs. We then correlated variables indicating SD susceptibility with algorithm-estimated SD velocities in twelve aSAH patients. Highly significant correlations supported the algorithm's validity. The trajectory search failed significantly more often for SDs recorded directly over emerging focal brain lesions suggesting in humans similar to animals that the complexity of SD propagation paths increase in tissue undergoing injury

Twin digital short period seismic Array Experiment at Stromboli Volcano

Two small arrays composed by short period (1 Hz) digital seismic stations, with an aperture of approximately 400 meters, were set up at Stromboli volcano (one at semaforo Labronzo, the other at Ginostra- Timpone del Fuoco) with the purpose of the spatial location of the high frequency source of the explosion quakes. About 75 explosion-quakes were recorded at both arrays, and constitute the available data base. We have planned to apply the zero-lag cross-correlation technique to the whole data set in order to obtain back-azimuth and apparent slowness of the coherent seismic phases. A preliminary analysis for both arrays show that the predominant back-azimuth for the first phase is oriented in the direction of , but not strictly coincident to, the crater area. Moreover some back-scattered arrivals are quite evident in the seismogram.INGV - Osservatorio VesuvianoUnpublishedope

A seismic array on Mt. Vesuvius

In November 1997 a seismic antenna (array) of short period seismometers was installed on the south-western flank of Mt. Vesuvius; aim of the experiment was to test the use of non-conventional devices for the seismic monitoring of this volcano. In 7 months local seismicity, regional earthquakes and samples of seismic noise were recorded by the array and organised in a data base. Local earthquakes and seismic noise have been analysed with array techniques to investigate the spectral, kinematic and polarization properties of the wavefield. Preliminary results show that the backazimuth of local earthquakes is oriented in the direction of the crater area. For some events, the source location has been constrained using a simplified back propagation in a 2-D velocity structure. The noise wavefield is characterized by the predominance of a sustained low frequency component (< 1Hz) whose source is located S-SE of the array. This low frequency signal has been interpreted as associated to the sea-loading in the gulf of Naples.Istituto Nazionale di Geofisica e Vulcanologia, Osservatorio VesuvianoPublished1.4. TTC - Sorveglianza sismologica delle aree vulcaniche attiveope