21,690 research outputs found

    Pairwise Network Information and Nonlinear Correlations

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    Reconstructing the structural connectivity between interacting units from observed activity is a challenge across many different disciplines. The fundamental first step is to establish whether or to what extent the interactions between the units can be considered pairwise and, thus, can be modeled as an interaction network with simple links corresponding to pairwise interactions. In principle this can be determined by comparing the maximum entropy given the bivariate probability distributions to the true joint entropy. In many practical cases this is not an option since the bivariate distributions needed may not be reliably estimated, or the optimization is too computationally expensive. Here we present an approach that allows one to use mutual informations as a proxy for the bivariate distributions. This has the advantage of being less computationally expensive and easier to estimate. We achieve this by introducing a novel entropy maximization scheme that is based on conditioning on entropies and mutual informations. This renders our approach typically superior to other methods based on linear approximations. The advantages of the proposed method are documented using oscillator networks and a resting-state human brain network as generic relevant examples

    Genotypic characterisation of Giardia from domestic dogs in the USA

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    The first large-scale urban survey of Giardia infections in dogs was undertaken in the USA. It involved several locations in the Western United States with Giardia isolates from microscopy-positive samples characterised by multi-locus PCR and sequencing. A high prevalence of Giardia was confirmed in asymptomatic domestic dogs, and for the first time, provides evidence that zoonotic assemblages/subgroups of Giardia occur frequently in domestic dogs living in urban environments, and more frequently than the dog specific assemblages

    Sampling Limits for Electron Tomography with Sparsity-exploiting Reconstructions

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    Electron tomography (ET) has become a standard technique for 3D characterization of materials at the nano-scale. Traditional reconstruction algorithms such as weighted back projection suffer from disruptive artifacts with insufficient projections. Popularized by compressed sensing, sparsity-exploiting algorithms have been applied to experimental ET data and show promise for improving reconstruction quality or reducing the total beam dose applied to a specimen. Nevertheless, theoretical bounds for these methods have been less explored in the context of ET applications. Here, we perform numerical simulations to investigate performance of l_1-norm and total-variation (TV) minimization under various imaging conditions. From 36,100 different simulated structures, our results show specimens with more complex structures generally require more projections for exact reconstruction. However, once sufficient data is acquired, dividing the beam dose over more projections provides no improvements - analogous to the traditional dose-fraction theorem. Moreover, a limited tilt range of +-75 or less can result in distorting artifacts in sparsity-exploiting reconstructions. The influence of optimization parameters on reconstructions is also discussed

    Reply to the comment by C. Capan and K. Behnia on "Nernst effect in poor conductors and in the cuprate superconductors" (cond-mat/0501288)

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    The comment criticisms (cond-mat/0501288) are completely out of line with the context of the commented theory (Phys. Rev. Lett. v.93, 217002 (2004)). The comment neglected essential parts of the theory, which actually addressed all relevant experimental observations. I argue that the coexistence of the large Nernst signal and the insulating-like in-plane resistivity in underdoped cuprates rules out the vortex scenario, but agrees remarkably well with our theory.Comment: 1 page, 1 figur

    The intersection of race, sexual orientation, socioeconomic status, trans identity, and mental health outcomes

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    The present study examined patterns in trans individuals’ multiple identities and mental health outcomes. Cluster 1 (socioeconomic and racial privilege; n = 239) was characterized by individuals who identified as trans women or cross-dressers, lesbian, bisexual, or questioning; had associates degrees; reported household incomes of 60,000ormoreayear;andwerenonLatinoWhite.Cluster2(educationalprivilege;n=191)wascharacterizedbyindividualswhoidentifiedastransmenorgenderqueer,gay,orqueer;hadabachelorsdegree;reportedhouseholdincomesof60,000 or more a year; and were non-Latino White. Cluster 2 (educational privilege; n = 191) was characterized by individuals who identified as trans men or genderqueer, gay, or queer; had a bachelor’s degree; reported household incomes of 10,000 or less a year; and were people of color. There was a pattern of individuals in Cluster 1 who identified with two privileged identities (identifying as White and having higher household incomes), whereas individuals in Cluster 2 identified only formal education as a privilege. Individuals in Cluster 2 reported statistically significant levels of anxiety. Implications of these results for future research and clinical practice are examined.Accepted manuscrip

    The importance of collegiality and reciprocal learning in the professional development of beginning teachers

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    This paper discusses factors which enhance induction experiences for beginning teachers. It reports the findings from case studies which explore the impact of new entrants to the teaching profession in Scotland. The data suggest that the most supportive induction processes mix both formal and informal elements, but that the informal elements such as collegiality, good communication and a welcoming workplace environment should not be underestimated. The study also highlights the potential benefits of a more collegiate environment for teachers across the career phases. Experienced teachers and new entrants had a range of experience to offer each other, thus creating more cohesive professional working which was supportive of early career teachers while encouraging reflection on practice among the more experienced professionals

    Structure and correlates of cognitive aging in a narrow age cohort

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    Aging-related changes occur for multiple domains of cognitive functioning. An accumulating body of research indicates that, rather than representing statistically independent phenomena, aging-related cognitive changes are moderately to strongly correlated across domains. However, previous studies have typically been conducted in age-heterogeneous samples over longitudinal time lags of 6 or more years, and have failed to consider whether results are robust to a comprehensive set of controls. Capitalizing on 3-year longitudinal data from the Lothian Birth Cohort of 1936, we took a longitudinal narrow age cohort approach to examine cross-domain cognitive change interrelations from ages 70 to 73 years. We fit multivariate latent difference score models to factors representing visuospatial ability, processing speed, memory, and crystallized ability. Changes were moderately interrelated, with a general factor of change accounting for 47% of the variance in changes across domains. Change interrelations persisted at close to full strength after controlling for a comprehensive set of demographic, physical, and medical factors including educational attainment, childhood intelligence, physical function, APOE genotype, smoking status, diagnosis of hypertension, diagnosis of cardiovascular disease, and diagnosis of diabetes. Thus, the positive manifold of aging-related cognitive changes is highly robust in that it can be detected in a narrow age cohort followed over a relatively brief longitudinal period, and persists even after controlling for many potential confounders

    Public Bikesharing in North America During a Period of Rapid Expansion: Understanding Business Models, Industry Trends & User Impacts, MTI Report 12-29

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    Public bikesharing—the shared use of a bicycle fleet—is an innovative transportation strategy that has recently emerged in major cities around the world, including North America. Information technology (IT)-based bikesharing systems typically position bicycles throughout an urban environment, among a network of docking stations, for immediate access. Trips can be one-way, round-trip, or both, depending on the operator. Bikesharing can serve as a first-and-last mile connector to other modes, as well as for both short and long distance destinations. In 2012, 22 IT-based public bikesharing systems were operating in the United States, with a total of 884,442 users and 7,549 bicycles. Four IT-based programs in Canada had a total of 197,419 users and 6,115 bicycles. Two IT-based programs in Mexico had a total of 71,611 users and 3,680 bicycles. (Membership numbers reflect the total number of short- and long-term users.) This study evaluates public bikesharing in North America, reviewing the change in travel behavior exhibited by members of different programs in the context of their business models and operational environment. This Phase II research builds on data collected during our Phase I research conducted in 2012. During the 2012 research (Phase I), researchers conducted 14 expert interviews with industry experts and public officials in the United States and Canada, as well as 19 interviews with the manager and/or key staff of IT-based bikesharing organizations. For more information on the Phase I research, please see the Shaheen et al., 2012 report Public Bikesharing in North America: Early Operator and User Understanding. For this Phase II study, an additional 23 interviews were conducted with IT-based bikesharing organizations in the United States, Canada, and Mexico in Spring 2013. Notable developments during this period include the ongoing expansion of public bikesharing in North America, including the recent launches of multiple large bikesharing programs in the United States (i.e., Citi Bike in New York City, Divvy in Chicago, and Bay Area Bike Share in the San Francisco Bay Area). In addition to expert interviews, the authors conducted two kinds of surveys with bikesharing users. One was the online member survey. This survey was sent to all people for whom the operator had an email address.The population of this survey was mainly annual members of the bikesharing system, and the members took the survey via a URL link sent to them from the operator. The second survey was an on-street survey. This survey was designed for anyone, including casual users (i.e., those who are not members of the system and use it on a short-term basis), to take “on-street” via a smartphone. The member survey was deployed in five cities: Montreal, Toronto, Salt Lake City, Minneapolis-Saint Paul, and Mexico City. The on-street survey was implemented in three cities: Boston, Salt Lake City, and San Antonio
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