Experiment Simulation Configurations Used in DUNE CDR

The LBNF/DUNE CDR describes the proposed physics program and experimental design at the conceptual design phase. Volume 2, entitled The Physics Program for DUNE at LBNF, outlines the scientific objectives and describes the physics studies that the DUNE collaboration will perform to address these objectives. The long-baseline physics sensitivity calculations presented in the DUNE CDR rely upon simulation of the neutrino beam line, simulation of neutrino interactions in the far detector, and a parameterized analysis of detector performance and systematic uncertainty. The purpose of this posting is to provide the results of these simulations to the community to facilitate phenomenological studies of long-baseline oscillation at LBNF/DUNE. Additionally, this posting includes GDML of the DUNE single-phase far detector for use in simulations. DUNE welcomes those interested in performing this work as members of the collaboration, but also recognizes the benefit of making these configurations readily available to the wider community.Comment: 9 pages, 4 figures, configurations in ancillary file

Long-Baseline Neutrino Facility (LBNF) and Deep Underground Neutrino Experiment (DUNE) Conceptual Design Report Volume 2: The Physics Program for DUNE at LBNF

The Physics Program for the Deep Underground Neutrino Experiment (DUNE) at the Fermilab Long-Baseline Neutrino Facility (LBNF) is described

The Long-Baseline Neutrino Experiment: Exploring Fundamental Symmetries of the Universe

The preponderance of matter over antimatter in the early Universe, the dynamics of the supernova bursts that produced the heavy elements necessary for life and whether protons eventually decay --- these mysteries at the forefront of particle physics and astrophysics are key to understanding the early evolution of our Universe, its current state and its eventual fate. The Long-Baseline Neutrino Experiment (LBNE) represents an extensively developed plan for a world-class experiment dedicated to addressing these questions. LBNE is conceived around three central components: (1) a new, high-intensity neutrino source generated from a megawatt-class proton accelerator at Fermi National Accelerator Laboratory, (2) a near neutrino detector just downstream of the source, and (3) a massive liquid argon time-projection chamber deployed as a far detector deep underground at the Sanford Underground Research Facility. This facility, located at the site of the former Homestake Mine in Lead, South Dakota, is approximately 1,300 km from the neutrino source at Fermilab -- a distance (baseline) that delivers optimal sensitivity to neutrino charge-parity symmetry violation and mass ordering effects. This ambitious yet cost-effective design incorporates scalability and flexibility and can accommodate a variety of upgrades and contributions. With its exceptional combination of experimental configuration, technical capabilities, and potential for transformative discoveries, LBNE promises to be a vital facility for the field of particle physics worldwide, providing physicists from around the globe with opportunities to collaborate in a twenty to thirty year program of exciting science. In this document we provide a comprehensive overview of LBNE's scientific objectives, its place in the landscape of neutrino physics worldwide, the technologies it will incorporate and the capabilities it will possess.Comment: Major update of previous version. This is the reference document for LBNE science program and current status. Chapters 1, 3, and 9 provide a comprehensive overview of LBNE's scientific objectives, its place in the landscape of neutrino physics worldwide, the technologies it will incorporate and the capabilities it will possess. 288 pages, 116 figure

The Long-Baseline Neutrino Experiment: Exploring Fundamental Symmetries of the Universe

Major update of previous version. This is the reference document for LBNE science program and current status. Chapters 1, 3, and 9 provide a comprehensive overview of LBNE's scientific objectives, its place in the landscape of neutrino physics worldwide, the technologies it will incorporate and the capabilities it will possess. 288 pages, 116 figuresMajor update of previous version. This is the reference document for LBNE science program and current status. Chapters 1, 3, and 9 provide a comprehensive overview of LBNE's scientific objectives, its place in the landscape of neutrino physics worldwide, the technologies it will incorporate and the capabilities it will possess. 288 pages, 116 figuresThe preponderance of matter over antimatter in the early Universe, the dynamics of the supernova bursts that produced the heavy elements necessary for life and whether protons eventually decay --- these mysteries at the forefront of particle physics and astrophysics are key to understanding the early evolution of our Universe, its current state and its eventual fate. The Long-Baseline Neutrino Experiment (LBNE) represents an extensively developed plan for a world-class experiment dedicated to addressing these questions. LBNE is conceived around three central components: (1) a new, high-intensity neutrino source generated from a megawatt-class proton accelerator at Fermi National Accelerator Laboratory, (2) a near neutrino detector just downstream of the source, and (3) a massive liquid argon time-projection chamber deployed as a far detector deep underground at the Sanford Underground Research Facility. This facility, located at the site of the former Homestake Mine in Lead, South Dakota, is approximately 1,300 km from the neutrino source at Fermilab -- a distance (baseline) that delivers optimal sensitivity to neutrino charge-parity symmetry violation and mass ordering effects. This ambitious yet cost-effective design incorporates scalability and flexibility and can accommodate a variety of upgrades and contributions. With its exceptional combination of experimental configuration, technical capabilities, and potential for transformative discoveries, LBNE promises to be a vital facility for the field of particle physics worldwide, providing physicists from around the globe with opportunities to collaborate in a twenty to thirty year program of exciting science. In this document we provide a comprehensive overview of LBNE's scientific objectives, its place in the landscape of neutrino physics worldwide, the technologies it will incorporate and the capabilities it will possess

Multi-objective routing optimisation for battery-powered wireless sensor mesh networks

Copyright © 2014 ACM2014 Conference on Genetic and Evolutionary Computation (GECCO ’14), Vancouver, BC, Canada, 12-16 July 2014This paper won the Best Paper award in the Real World Applications category at the GECCO ’14 conferenceMesh network topologies are becoming increasingly popular in battery powered wireless sensor networks, primarily due to the extension of network range and resilience against routing failures. However, multi-hop mesh networks suffer from higher energy costs, and the routing strategy directly affects the lifetime of nodes with limited energy sources. Hence while planning routes there are trade-offs to be considered between individual and system-wide battery lifetimes. We present a novel multi-objective routing optimisation approach using evolutionary algorithms to approximate the optimal trade-off between minimum lifetime and the average lifetime of nodes in the network. In order to accomplish this combinatorial optimisation rapidly and thus permit dynamic optimisation for self-healing networks, our approach uses novel k-shortest paths based search space pruning in conjunction with a new edge metric, which associates the energy cost at a pair of nodes with the link between them. We demonstrate our solution on a real network, deployed in the Victoria & Albert Museum, London. We show that this approach provides better trade-off solutions in comparison to the minimum energy option, and how a combination of solutions over the lifetime of the network can enhance the overall minimum lifetime

FINE NEEDLE ASPIRATION CYTOLOGY OF BREAST LUMP IN T.U. TEACHING HOSPITAL

This is a retrospective study of fine needle aspiration cytology of breast lesions performed between May 1998 and April 2000. During this period, a total of 2001 fine needle aspirations were done in the Tribhuvan Universtiy Teaching Hospital (TUTH), of which 470 (23.48 %) were of the breast. Fibrocystic disease found to be the most frequent and was diagnosed in 183 cases (38.9%). Fibroadenoma was the third common pathological condition, numbering 61 (12.9%). Malignant conditions of the breast were 72 cases (15.3%). During these two years, histological diagnosis was available in 154 cases. Histological examination revealed benign conditions in 74 cases (48%), malignancy in 59 cases (38.3%) and inflammatory & lactational changes in 21 cases (13.7%). Out of these 154 cases, 71 cases had also undergone fine needle aspiration cytology. The 36 cases diagnosed as benign cytologically, 34 cases were also benign histologically, whereas 2 cases turned out to be malignant. Out of 37 cases that were histologically malignant, on cytology 35 cases were diagnosed as malignant. The sensitivity and specificity of cytopathological diagnosis for breast lesions was 100% and 94.6% respectively. Inflammatory lesions correlated well cytologically and histolgically. FNAC is a safe and rapid diagnostic method for evaluation of various lesions. However, there are possibilities of false negative and false positive results because of wide range of appearance of breast lesions. Key Words: Breast lumps, Fine Needle Aspiration Cytology, Benign Lesions, Malignant Lesions, Histopathology and Correlation