7 research outputs found
ソウセツ ショウニ BIPHENOTYPIC LEUKEMIA ノ ブンルイ ノ ココロミ
Seven hundred and forty-five newly diagnosed patients with acute leukemias between 1978 and 1990 were classified on the basis of immunological phenotype. The incidence of subclassification of acute leukemias in this study was as follows: 522 patients with ALL (70%), 139 patiens with ANLL (18%), 29 patients with biphenotypic leukemia, 8 patients with Ph1-positive acute leukemia, and 46 patients with infantile leukemia. ALLs were classified into common ALL (77%), T-ALL (15%), B-ALL (4%), and unclassified ALL (3%). Biphenotypic leukemias were categorized into 4 groups as follows; 1) common ALL with positive myelomonocytic antigen(s) (N=11), 2) unclassified ALL with positive myelomonocytic antigen(s) (N=5), 3) ANLL with positive B-lymphoid antigen(s) (N=4) and 4) acute leukemia with positive T-lymphoid and myeloid antigen(s). Among these 4 groups of biphenotypic leukemia, groups 2 and 4 disclosed a poor prognosis as was reported in infantile leukemia and Ph1-positive acute leukemia. Many questions regarding the biological and clinical aspects of biphenotypic leukemias stiil remain to be solved, but the precise and detailed sutailed subclassifications of acute leukemias will establish an appropriete strategy of therapy.journal articl
作物体内における重金属元素の挙動に関する研究 <特別寄稿>
application/pdfl.ln1959,comparative studies on the response of rice plants to toxic levels of manganese,cobalt,nickel,zinc,copper and cadmium were started using an emission spectrophotograph.Toxic order of these heavy metal elementswas:copper,cadmium>nickel>cobalt>zinc>manganese.Mechanisms of grain yield reduction resulting from theapplication of toxic levels of tbese heavy metal elements were elucidated.
2.Next,a series of methods were proposed for the characterization of trace amounts of heavy metal elements inplant tissues by using atomic absorption spectrometry and radioisotope technique for metal detection.
3.Microdistribution and chemical form of cadmium in polluted rice grains were examined by the above mentioned techniques.More than 80% of cadmium in a grain were found in endosperm,edible part of rice grain. Cadmiumin endosperm was found to occur chiefly in the form of cadmium-glutelin complex.
4.Then,Studies were conducted concerning the behabior of zinc at normal levels within rice plants. Characteristicfeatures of the behavior of root-fed zinc were as follows .
1)Zinc absorbed by roots and then transported in the xylem, was retrieved from the transpiration stream before reaching at the leaves , high in the transpiration activity,and then actively transported to the sink regions at that time;i.e,active meristems of the developing leaves,panicleprimordia,developing rice grains and so on.
2)The main site of the retrieval exists and actively operates in thenodes to which photosynthetically active leaves are attachcd.The short-cut pathway of zinc in the node was elucidated by means of semimicroautoradicgraphy on the base of the recent information obtained by Kawahara et al.concerning the microstructure of the node of rice plants.
5.Comparative studies were conducted concerning the behavior of root-fed cadmium at relatively low levels andthat of zinc at normal leveles within rice plants. Althogh most of the root-fed cadmium were firmly held by theroots, the behavior of the trace amounts of cadmium, transported in the xylem, was similar totbat of zinc.Thecapacity of the retrieval mechanism in the node was fairly high for cadmium, too. Based on the results obtaimedfoom the tracer experiments conducted at the early ripening stage, we deduced that mecbanisms, operating in thenodes in collecting trace amount of essential zinc from the transpiration stream and in transporting them activelyto the sink regions, cannot discriminate cadmium from zinc, thus contributing to the accumulation of nonessentialcadmium in rice grains.
6.Physiological role of zinc, remarkably accumulated in meristems, was examined. When the concentration ofzinc in apical meristems was reduced to the levels less than 100ppm, the amount of 80S ribosomes in cytoplasmdecreased remarkably, followed by rapid decrease in the amount of soluble proteins, suggesting that zinc contributesto the integrity of 80S ribosomes, the site for protein synthesis in cytoplasm. Further investigations are now beingcarried out concerning the effect of zinc deficiency on the transcription process of genetic information.departmental bulletin pape
サブバンド信号処理に基づくアダプティブアレーアンテナの開発
時空間信号処理を行うアダプティブアレーは、将来の高速移動体通信システムにおいて有効なマルチパス対策となるものと期待される反面、適応的に制御される重み係数の数が非常に多くなることから、ハードウェアへの実装にあたってその膨大な計算負荷が問題となる。このため、計算量の削減が実用化への鍵となっているということができる。本論文では、計算量の大幅な削減が可能なサブバンド信号処理を行うアダプティブアレーを、市販のDSP(Digital Signal Processor)を用いてハードウェアに実装した。そこでまず、必要な信号処理の各部に必要なDSPの数を示すことにより、ハードウェア規模を明らかにした。次に、電波暗室内において2波の簡単なマルチパス環境を構成し、その下で基本性能の実証実験を行って、理論値とほぼ一致する性能が得られることを確認した。journal articl
