カンゴ ケイカク カイジ ヲ ココロミテ カンゴ ニ オケル インフォームドコンセント ヲ カンガエル

報

An Immunobiochemical Significance to Do Quantitative and Qualitative Analysis of Serum Amyloid A Protein (SAA), C-reactive Protein (CRP) Included in Various Body Fluid Obtained from Mother and Perinate on Perinatal Period

Serum amyloid A protein (SAA) and C-reactive protein (CRP) are one of the human plasma proteins that have been recognized as an important host defense molecule. It is reported that SAA is produced with the mammary gland which is an extrahepatic producing tissue in various mammals except human and being secreted into colostrum. We have previously made clear that CRP is included in human colostrum and also what an automated commercially available latex-enhanced assay is effective to explore SAA in human colostrum and to measure its concentration. Consequently, the immunobiological significance of SAA and CRP contained in human colostrum has been of major concern. In this study, we examined to measure of these concentration by the high sensitive assay and to investigate the molecular attributes by western blotting. SAA was contained in the all of breast milk obtained from seventeen cases available. The mean concentration of SAA included in the breast milk increased from 0.135±0.33 μg/ml of the childbirth day to 1.494±1.17μg/ml in the observed puerperal period. There was a peak of the level of SAA on the third puerperium day. It was in contrast with the level of the milk CRP having reached a peak on the second puerperium day, and both levels of the blood SAA and CRP having become a peak on the first puerperium day. The molecular weight of SAA included in breast milk was 12 kDa the same as maternal blood, but CRP had a difference among the two materials in contrast with SAA. As for the molecular weight of CRP included in colostrum, different two molecules were observed. One was 23 kDa with a known molecule same as being included in the maternal blood, the other was larger in about 50 kDa. Though CRP had not been included in feces of infant after ablactation, the CRP molecules included in neonatal feces after lactation was molecular weight of 23 kDa the same as breast milk. Furthermore CRP was also contained in meconium, but the molecular weight was not identified. This is the initial report that showed that SAA included in human breast milk is arrived in maximum on the third puerperium day, and showed that CRP have different molecular weight between maternal blood and colostrum whereas SAA don\u27t have a difference. That SAA in mammary gland epithelial cells is induced by prolactin or lipopolysaccharide, that SAA increases intestinal mucin to provide a protective barrier and inhibits adhesion to the gut wall of enteropathogenic Escherichia coli has been recently reported by other researchers. When we consider them and evaluate this study, it is speculated that SAA and CRP which would be transferred from mother to a newborn infant through colostrum carry an important role to confer phylaxis ability on the newborn infant

不安状態に陥った患者への援助を通して

Article信州大学医学部附属病院看護研究集録 1982: 62-65 (1982)departmental bulletin pape

養護教諭が経験した心の健康問題のヒヤリハット事例の検討 ―養護診断及び対応ポイントに関する一考察―

The purpose of this study was to make it a study material to prevent inadequate incidents in correspondence of Yogo teachers to mental health problems. We analyzed the cause of incidents experienced by Yogo teachers actually, and clarified factors that occurred due to the problems of Yogo teachers\u27 response.Factors of incidents of mental health problems are [inappropriate response], [belief], [mistake in consideration], [insufficient pursuit], [observation, inquiry, lack of palpation], [insufficient situation grasping], [inadequacy of school system], [misidentification of priority] 8 items were found. As a concrete measure for these problems / cause factors, "A: to study about contemporary health problems", "B: to study about interviews, palpation, observation", "C: don’t correspondence only of main symptoms", "D: Accurately collect information", "E: Looking back to allow judgment to be corrected", "F: Comprehensively looking at", "G: collaboration among teachers from everyday and construction of support system", "H: don’t leave suspicions and doubts, pursue", "I: retrospective and study on Yogo diagnosis and response", "J: don’t mistake to judge the urgency of job content and its response".From these facts, it was suggested that the mental condition of the Yogo teacher himself / herself was related to the occurrence factor of the incorrect incident report of the mental health problem, and the incident report happened. In order to identify necessary abilities and acquire the ability to cope with changes in the health problems of children, it is expected that attitudes that the Yogo teacher themselves widen their perspectives and constantly learn

入退院を繰り返す一分裂病患者の自立への援助

Article信州大学医学部附属病院看護研究集録 1983: 75-79 (1983)departmental bulletin pape

COVID-19パンデミックにおける小中学生の摂食障害患者の実態調査報告

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身体疾患を伴う分裂病患者の自宅療養への働きかけ

Article信州大学医学部附属病院看護研究集録 1981: 80-84 (1981)departmental bulletin pape

問題行動を追求し家庭環境の調節により社会復帰できた一症例

Article信州大学医学部附属病院看護研究集録 1980: 68-71 (1980)departmental bulletin pape