Research progress on the objectification, quantitation and standardization of tongue manifestation in traditional Chinese medicine

舌诊是中医诊断学的重要组成部分,舌象在中医临床治疗中具有重要的诊断意义与辨证价值。传统中医舌象易受主客观因素影响,难以客观化、定量化、标准化,严; 重制约舌象临床应用及发展。随着医学、计算机等现代技术的迅猛发展,中医舌象客观量化研究取得了长足进步,并被应用于基础及临床研究。文章对近几年中医舌; 象采集分析系统、舌象定量化研究、现代仪器应用与舌象基础研究进行概述,为舌象应用于临床治疗提供客观、科学的思路与方法。Tongue diagnosis is an important part of traditional Chinese medicine; (TCM), and the tongue manifestation is also important in the diagnosis; and syndrome differentiation in TCM clinical treatment. However, due to; the lack of objective, quantitative and standardized valuation, with it; being susceptible to subjective and objective factors, the application; and development of traditional tongue diagnosis is limited for a long; period. Recently, with the rapid development of medical and other modern; technology, the objectification, quantitation and standardization of TCM; tongue manifestation have been received great progress, including the; progress in basic and clinical researches. Recent researches on the; tongue image acquisition and analysis system, the quantitation of tongue; manifestation, the application of modern instruments and the basic; research in tongue manifestation were reviewed to provide certain; objective and scientific ideas and methods for TCM tongue manifestation.教育部新世纪优秀人才支持计划; 中国博士后科学基金面上项

Psychological resilience features of urban migrant children and rural left-behind children in Sichuan province of China

目的:探索四川省流动儿童和留守儿童心理复原力特点及差异。方法:使用青少年心理复原力量表对四川省成都、广元、宜宾、绵阳的打工子弟学校和留守儿童较集中的农村学校1 391名在校学生(504名小学生和887名初中生)进行调查。结果:中学生组流动儿童在心理复原力上得分(128.11±21.70)显著低于对照组普通学生(132.87±23.22)和留守儿童(135.61±22.77),F0.05(2,884)=8.076,P<0.001,流动儿童在心理复原力除同伴外的4个维度上(包括家庭、学校、社会以及自身特质)得分均显著低于对照组儿童(家庭:F0.05(2,884)=7.820,P<0.001;学校:F0.05(2,884)=5.041,P=0.007;社会:F0.05(2,884)=9.261,P<0.001;自身特质:F0.05(2,884)=3.510,P=0.030),而留守儿童与对照组儿童相比差异无统计学意义。不同的年级和不同的性别间,流动儿童和留守儿童在心理复原力的不同维度上差异有统计学意义。结论:农民工子女,尤其是流动儿童,整体来说心理复原力较差,从外界环境获得的心理资源和支持较少,对外部环境的参与也相对较少

双金属Zn-Fe金属有机框架的制备及其丙酮气敏特性研究

采用溶剂热法制备了双金属Zn-Fe金属有机框架结构(Zn-Fe MOF),利用扫描电子显微镜(SEM)、透射电子显微镜(TEM)和X射线衍射仪(XRD)对其微观形貌和晶相进行表征分析。结果表明:制备的双金属Zn-Fe MOF为纳米球结构,其直径约为150 nm。同时,制备了基于双金属Zn-Fe MOF材料的气体传感器件,研究了其对丙酮的气敏特性。测试结果表明:基于双金属Zn-Fe MOF的气体传感器对丙酮的最佳工作温度为210℃。在最佳工作温度下,对浓度为1×10-6的丙酮气体响应可达到2,响应/恢复时间分别为6 s/13 s,且具有较好的重复性和长期稳定性。最后,对基于双金属Zn-Fe MOF气体传感器的气敏机理进行了讨论。国家自然科学基金项目(51205274);;山西省人才专项项目(2016[36]);;山西省自然基金项目(2016[39]);;山西省高校科技创新研究项目(2016[37]);;山西省归国留学择优项目([2014]95);;山西省归国留学基金项目(2013-035);;山西省科技重大专项项目(20121101004);;山西省高等学校特色重点学科建设项目(晋教财[2012]45号

Bacterial community and its relation to environmental variables in a subtropical stratified reservoir for drinking water supply in autumn

水库在我国东南沿海地区是重要的饮用水水源地,对地区经济发展和社会稳定起到重要作用。选择亚热带地区典型的热分层水库——福建莆田东圳水库,于2011年秋季稳定分层期,以水体温度的垂直变化特征为依据进行分层采样。应用PCrdggE和克隆测序的方法研究浮游细菌群落的垂直分布特征,利用多元统计分析揭示细菌群落与热分层水体理化指标之间的关系。结果显示:溶解氧、电导率、叶绿素A、总氮、氨氮及硝氮在上下层水体中的分布有显著差异,下层缺氧区细菌的SHAnnOnWIEnEr指数和dggE条带数明显高于上层好氧区,表明东圳水库热分层水体中存在明显的物理、化学及生物分层现象。测序结果表明β-变形菌可能是东圳水库中占优势的细菌类群,统计结果提示溶解氧是显著影响细菌群落组成的环境因子。热分层水体的物理化学分层与水体细菌群落结构密切相关,提示水库生态学研究应对水体热分层给予重视。Fujian reservoirs in southeast China are important water resources for economic and social sustainable development,although few have been studied previously.Dongzhen Reservoir,a typical subtropical stratified reservoir in Fujian,was chosen for investigation of bacterial distribution,composition and diversity in autumn 2011.As the only built large reservoir in Putian City,it plays an important role in irrigation,flood control,hydroelectric power,and water supply.Dongzhen Reservoir shows an obvious phenomenon of water thermal stratification during summer and autumn,thus creates a unique gradient of environmental variables along the water column.We investigated the bacterial community and its relation to environmental variables in this study for a better understanding of vertical distribution of bacterial community and theprimary environmental drivers in a stratified reservoir.Five water samples were collected from five different depths according to the vertical changes of temperature.Both PCR-DGGE and sequencing were used to investigate the bacterial community and diversity.Moreover,physical and chemical parameters were measured according to the national standard methods.Multivariate statistical techniques were used to examine the relationship between bacterial community and environmental variables.Principal component analysis( PCA) clearly showed that water temperature,dissolved oxygen( DO),chlorophyll a( Chl a),total nitrogen( TN),ammonia nitrogen( NH4-N),nitrite / nitrate nitrogen( NOx-N) and electric conductivity of the upper aerobic zone were differed from those of the deeper anoxic zone.Both the number of DGGE bands and the Shannon-Wiener index of the deeper anoxic zone were higher than those of the upper aerobic zone.Further,two groups were distinguished by the cluster analysis of bacterial communities based on the Bray-Curtis similarity.Thus,Dongzhen Reservoir presented an obviously physical,chemical,and biological stratified phenomenon.Seven bands that common to all sampling depths were extracted and sequenced,and among which four were identified as Betaproteobacteria,indicating that Betaproteobacteria were the most dominant taxa in Dongzhen Reservoir in autumn.Bacterial community composition and diversity differed greatly among different sampling depths,and these differences were closely related to the physical and chemical stratification of the water body.Redundancy analysis( RDA) demonstrated DO was the significant environmental variable that shaping the bacterial community and diversity( P < 0.01).Therefore,we should pay more attention to DO and thermal stratification of reservoirs for sustainable reservoir management.国家重大科学研究计划(2012CB956103); 中国科学院知识创新工程方向项目(KZCX2-YW-QN401); 国家自然科学基金面上项目(31172114); 福建省杰出青年科学基金项目(2012J06009

基于连接构筑图谱的岛叶-岛盖癫痫症状学亚组

&lt;正&gt;目的由于岛叶-岛盖涉及多种生理功能和广泛的网络联系,岛叶-岛盖癫痫发作可以表现为各种不同的症状学。本研究旨在确定岛叶-岛盖癫痫的症状学亚组,并将它们与基于连接构筑的图谱亚区相联系。方法我们回顾性收集了37例来自国内三个癫痫中心SEEG证实的岛叶-岛盖癫痫患者。引入了一个新的基于解剖性和功能性连接的人类脑图谱(Brainnetome Atlas,BNA)。</p

Psychological resilience features of urban migrant children and rural left-behind children in Sichuan province of China

目的：探索四川省流动儿童和留守儿童心理复原力特点及差异。方法：使用青少年心理复原力量表对四川省成都、广元、宜宾、绵阳的打工子弟学校和留守儿童较集中的农村学校1 391名在校学生（504名小学生和887名初中生）进行调查。结果：中学生组流动儿童在心理复原力上得分（128.11±21.70）显著低于对照组普通学生（132.87±23.22）和留守儿童（135.61±22.77）,F0.05（2,884）=8.076,P〈0.001,流动儿童在心理复原力除同伴外的4个维度上（包括家庭、学校、社会以及自身特质）得分均显著低于对照组儿童（家庭：F0.05（2,884）=7.820,P〈0.001;学校：F0.05（2,884）=5.041,P=0.007;社会：F0.05（2,884）=9.261,P〈0.001;自身特质：F0.05（2,884）=3.510,P=0.030）,而留守儿童与对照组儿童相比差异无统计学意义。不同的年级和不同的性别间,流动儿童和留守儿童在心理复原力的不同维度上差异有统计学意义。结论：农民工子女,尤其是流动儿童,整体来说心理复原力较差,从外界环境获得的心理资源和支持较少,对外部环境的参与也相对较少