Illness Experiences among Chinese College Students: A Negotiation Process between Social Connections and Protection of Self-Image

This study explored the experience of illness in relation to self-image, biographical disruption, and the process of coping through semi-structured interviews with students of a university in China. Twelve students were recruited under three categories, having a physical chronic illness, mental health illness, and chronic multiple morbidities. Indepth interviews were conducted and content analyses were applied to their recordings to identify major themes and subordinate themes in the illness experience. Results showed a distorted sense of self and biographical disruptions in young adulthood were common, as reported by the respondents. Students tried to cope with these disruptions with both individual strengths and social support, but not always with positive results. Reconstruction of self, in the analysis of illness experiences, was found a crucial strategy in overcoming disruptions. Social support of evaluative nature facilitated the adoption of the reconstruction strategy. A network-building approach is recommended for student services in higher education whereas further research is necessary to understand the processes of self-reconstruction

Turning Disruption into Growth Opportunity: The Red Team Strategy

The purpose of this paper is to propose a broadened and integrated red team strategy with concrete steps to help companies better deal with the disruptive forces prevalent in our world today and turn disruptions into growth. We suggest four key steps to help companies implement the red team strategy: 1) create a red team culture and encourage diverse perspectives, 2) establish an independent red team to overcome organizational inertia, 3) use the red team to embrace disruption and growth opportunities, and 4) take a milestone approach to red team execution and resource allocation. Our red team strategy provides concrete steps to help companies in their efforts to adapt to and capitalize on disruptive forces

A Survey of Explainable Graph Neural Networks: Taxonomy and Evaluation Metrics

Graph neural networks (GNNs) have demonstrated a significant boost in prediction performance on graph data. At the same time, the predictions made by these models are often hard to interpret. In that regard, many efforts have been made to explain the prediction mechanisms of these models from perspectives such as GNNExplainer, XGNN and PGExplainer. Although such works present systematic frameworks to interpret GNNs, a holistic review for explainable GNNs is unavailable. In this survey, we present a comprehensive review of explainability techniques developed for GNNs. We focus on explainable graph neural networks and categorize them based on the use of explainable methods. We further provide the common performance metrics for GNNs explanations and point out several future research directions

Future-time framing: The effect of language on corporate future orientation

We examine how international variation in corporate future-oriented behavior, such as corporate social responsibility (CSR) and research and development (R&D) investment, could partially stem from characteristics of the languages spoken at firms. We develop a future-time framing perspective rooted in the literatures on organizational categorization and framing. Our theory and hypotheses focus on how companies with working languages that obligatorily separate the future tense and the present tense engage less in future-oriented behaviors, and this effect is attenuated by exposure to multilingual environments. The results based on a large global sample of firms from 39 countries support our theory, highlighting the importance of language in affecting organizational behavior around the world

Oxytocin is an age-specific circulating hormone that is necessary for muscle maintenance and regeneration.

The regenerative capacity of skeletal muscle declines with age. Previous studies suggest that this process can be reversed by exposure to young circulation; however, systemic age-specific factors responsible for this phenomenon are largely unknown. Here we report that oxytocin--a hormone best known for its role in lactation, parturition and social behaviours--is required for proper muscle tissue regeneration and homeostasis, and that plasma levels of oxytocin decline with age. Inhibition of oxytocin signalling in young animals reduces muscle regeneration, whereas systemic administration of oxytocin rapidly improves muscle regeneration by enhancing aged muscle stem cell activation/proliferation through activation of the MAPK/ERK signalling pathway. We further show that the genetic lack of oxytocin does not cause a developmental defect in muscle but instead leads to premature sarcopenia. Considering that oxytocin is an FDA-approved drug, this work reveals a potential novel and safe way to combat or prevent skeletal muscle ageing

Training the Next Generation of Family Medicine Providers through Group Buprenorphine-Naloxone Visits

Introduction: The rise in opioid use disorders (OUD) and fatal overdoses highlight the need to expand access to and capacity for treating OUD. Medication Assisted Treatment (MAT), a medication/group visit model, done in the office setting, is an effective remedy for treating OUD. Understanding residents’ perspectives on their clinical training in MAT can inform the design of a more effective and responsive curriculum. Methods: A qualitative study using group semi-structured interviews with residents in an urban family medicine residency rotating through a federally qualified health center. Interviews centered on strengths and weaknesses of the MAT program, resident likeliness to prescribe MAT, and potential training that would boost confidence were conducted. Grounded theory was utilized to identify themes among transcripts. Results: Four interrelated themes emerged: modeling and mentorship, harm reduction, skills, and intent. Residents’ desire to treat and views on harm reduction, combined with their skills and mentorship, give them the confidence and intent to utilize MAT post-residency. Discussion: Residents have the desire to prescribe MAT post-residency but lack confidence to do so. This can be attributed to a lack of modeling, mentorship, and skills developed within residency. Addition of this into programs, combined with exposure to harm-reduction as a principle and practice, must be incorporated into programs and could play an important role in closing the “treatment gap” by training the next generation of providers in providing MAT