Effects of PCB congeners on the immune function of Mytilus hemocytes: alterations of tyrosine kinase-mediated cell signaling.

none7openL. CANESI; C. CIACCI; M. BETTI; A. SCARPATO; B. CITTERIO; C. PRUZZO; G. GALLOCanesi, Laura; Ciacci, Caterina; Betti, Michele; A., Scarpato; Citterio, Barbara; C., Pruzzo; G., Gall

A new technique for infrared scintillation measurements

open7siWe propose a new technique to measure the infrared scintillation light yield of rare earth doped crystals by comparing it to near UV–visible scintillation of a calibrated Pr:(Lu0.75Y0.25)3Al5O12 sample. As an example, we apply this technique to provide the light yield in visible and infrared range up to 1700 nm of this crystal.openChiossi, F; Brylew, K.; Borghesani, A.F.; Braggio, C.; Carugno, G.; Drozdowski, W.; Guarise, M.Chiossi, Federico; Brylew, K.; Borghesani, ARMANDO-FRANCESCO; Braggio, Caterina; Carugno, Giovanni; Drozdowski, W.; Guarise, Marc

Chemical behavior and in vitro activity of mixed phosphine gold(I)compounds on melanoma cell lines.

7partially_openCARUSO F; PETTINARI C; PADUANO F; VILLA R; MARCHETTI F; E. MONTI; ROSSI MCaruso, F; Pettinari, C; Paduano, F; Villa, R; Marchetti, F; Monti, ELENA CATERINA; Rossi, M

Caterina Sforza and Experimenti Translation into English and historical-linguistic analysis of some of her recipes

Caterina Sforza, Countess of Forlì from 1480 to 1500, was an intrepid and shrewd ruler, a mother, a lover, a woman with an eager interest in every field of knowledge, especially in science and experiments. Throughout her whole life, she devoted herself to experimenting and collecting hundreds of alchemical, cosmetic and medical recipes in a manuscript today known as “Experimenti”. This paper will include two chapters: in the first one, a biography of Caterina Sforza will be presented, together with a paragraph dedicated to her passion for botany and chemistry, which represent the foundation for her collection of recipes. Then, the reader will find a narration of the many changes of ownership and adventurous vicissitudes her manuscript experienced, thanks to which it is today possible to access Caterina’s remedies. The second chapter will contain the translation into present-day English of six recipes found in “Experimenti”. Each translation will be followed by the historical-linguistic analysis of some key words extracted from the original recipes: the analysis will base on the comparison between their Renaissance Italian translation and their current English meaning and spelling. An essential tool for this will be John Florio’s dictionary, first published in 1598 and considered the first extensive Italian-English dictionary. The aim of this paper is not only to make Caterina’s experiments accessible to an English public, but also to explore the development of the English language on different levels. Firstly, its evolution in time, from Early Modern English to today’s English. Secondly, its evolution in space, taking into consideration its immense spread all over the world through colonization (which, at the time Caterina Sforza and John Florio were alive, had only just begun), and the consequent many varieties of English existing now. Thirdly, its evolution with regard to the Italian language and culture

Prognostic relevance of a T-type calcium channels gene signature in solid tumours: A correlation ready for clinical validation

BackgroundT-type calcium channels (TTCCs) mediate calcium influx across the cell membrane. TTCCs regulate numerous physiological processes including cardiac pacemaking and neuronal activity. In addition, they have been implicated in the proliferation, migration and differentiation of tumour tissues. Although the signalling events downstream of TTCC-mediated calcium influx are not fully elucidated, it is clear that variations in the expression of TTCCs promote tumour formation and hinder response to treatment.MethodsWe examined the expression of TTCC genes (all three subtypes; CACNA-1G, CACNA-1H and CACNA-1I) and their prognostic value in three major solid tumours (i.e. gastric, lung and ovarian cancers) via a publicly accessible database.ResultsIn gastric cancer, expression of all the CACNA genes was associated with overall survival (OS) among stage I-IV patients (all pConclusionsAlterations in CACNA gene expression are linked to tumour prognosis. Gastric cancer represents the most promising setting for further evaluation

Molecular Sensors and Modulators of Thermoreception

Peer reviewedPostprin

Displaying Lives: the Narrative of Objects in Biographical Exhibitions

Biographical exhibitions are a museum practice that asks for critical consideration. Grounding the argument in critical theory, social studies and museum theory, the article explores the narrative function of objects in biographical exhibitions by addressing the social significance of objects in relation to biography and their relevance when presented into an exhibition display. Central is the concept of objects as ‘biographical relics’ that are culturally fetishized in biographical narratives. This raises questions about biographical reliability and the cultural role that such objects plays in exhibition narratives as bearers of reality and as metonymical icons of the biographical subject. The article considers examples of biographical exhibitions of diverse figures such as Gregor Mendel, Madame de Pompadour and Roland Barthes, and the role that personal items, but also portraits and photographs, play in them