Navigation of mini swimmers in channel networks with magnetic fields

Controlled navigation of swimming micro robots inside fluid filled channels is necessary for applications in living tissues and vessels. Hydrodynamic behavior inside channels and interaction with channel walls need to be understood well for successful design and control of these surgical-tools-to-be. In this study, two different mechanisms are used for forward and lateral motion: rotation of helices in the direction of the helical axis leads to forward motion in the viscous fluid, and rolling due to wall traction results with the lateral motion near the wall. Experiments are conducted using a magnetic helical swimmer having 1.5 mm in length and 0.5 mm in diameter placed inside two different glycerol-filled channels with rectangular cross sections. The strength, direction and rotational frequency of the externally applied rotating magnetic field are used as inputs to control the position and direction of the micro swimmer in Y- and T-shaped channels

Linear actuators for locomotion of microrobots

University of Technology, Sydney. Faculty of Engineering.The successful development of the miniaturisation techniques for electronic components and devices has paved the way for the miniaturisation in other technological fields. In the past two decades, the research achievements in micromechatronics have spurred fast development of micro machines and micro robotic systems. Miniature or micro actuators are the critical components to make these machines more dexterous, compact and cost effective. The main purpose of this dissertation is to develop micro actuators suitable for the locomotion of an in-pipe or endoscopic microrobot. The content of the thesis covers the selection of the actuation principle, robotic system design, actuator design and prototype construction, performance analysis, and design, analysis, and implementation of the appropriate drive control system. Among different types of actuation principles, piezoelectric and electromagnetic actuators are the two major candidates for the micro robotic systems. In order to find a suitable actuation principle for the desired robotic application, a comparative study was conducted on the scaling effects, attainable energy density, and dynamic performances of both types of actuators. Through the study, it was concluded that the electromagnetic actuator is more suitable for the endoscopic microrobot. Linear actuators are the common design used for the locomotion of microrobots due to many advantages compared to their rotational counterparts. Through a thorough review and comparison of the electromagnetic linear actuator topologies, a moving-coil tubular linear actuator was chosen as the first design due to its simplest structure. Via the magnetic circuit analysis and numerical magnetic field solutions, the actuator was designed for optimum force capability, and the electromagnetic force and the machine parameters of the actuator were predicted. According to the results obtained from the magnetic field analysis, the dynamic model of the actuation system with a driving control scheme was established and used in the actuation performance analysis of the robotic system. Based on the experience achieved through the first design, a new moving-magnet tubular linear actuator was designed. The methodology developed in the design and analysis of the moving-coil linear actuator was adopted for the moving-magnet actuator design. However, the optimal design is more complicated due to the multi-pole and multi-phase structure of the moving-magnet actuator. The electromagnetic force of the actuator was analysed under the condition of different excitation methods. An enhanced parameter computation method is proposed for predicting the actuator parameters. Based on the results of magnetic field analysis, a comprehensive dynamic model of the actuator was developed. Through the coupled field-circuit analysis, this model can predict accurately the dynamic performance of the actuator. The characteristics analysis shows that the performance of the moving-magnet actuator is much better than that of the moving-coil actuator. Two prototypes of the moving-magnet tubular linear actuator with different dimensions were constructed to verify the performance and the scaling theory. Various precision machining techniques were employed during the fabrication. The performances and parameters of the two different prototypes were measured and the results agree substantially with the theory. The brushless DC drive method was chosen for the driving control of the proposed linear actuator because of the compact circuit topology and simple implementation, which are two essential factors for micro applications. A sensorless control scheme based on the back EMF was developed as physical position sensors are not permitted in such a micro system. The control scheme was then applied to the locomotion control of the proposed microrobot. The system simulation shows that the control performances of both the actuator and microrobot are satisfactory. A dSPACE prototyping system based driving control hardware was designed and implemented to experimentally verify the control design. The experimental results agree substantially with the theoretical work

Structured light enables biomimetic swimming and versatile locomotion of photoresponsive soft microrobots.

Microorganisms move in challenging environments by periodic changes in body shape. In contrast, current artificial microrobots cannot actively deform, exhibiting at best passive bending under external fields. Here, by taking advantage of the wireless, scalable and spatiotemporally selective capabilities that light allows, we show that soft microrobots consisting of photoactive liquid-crystal elastomers can be driven by structured monochromatic light to perform sophisticated biomimetic motions. We realize continuum yet selectively addressable artificial microswimmers that generate travelling-wave motions to self-propel without external forces or torques, as well as microrobots capable of versatile locomotion behaviours on demand. Both theoretical predictions and experimental results confirm that multiple gaits, mimicking either symplectic or antiplectic metachrony of ciliate protozoa, can be achieved with single microswimmers. The principle of using structured light can be extended to other applications that require microscale actuation with sophisticated spatiotemporal coordination for advanced microrobotic technologies.This work was in part supported by the European Research Council under the ERC Grant agreements 278213 and 291349, and the DFG as part of the project SPP 1726 (microswimmers, FI 1966/1-1). SP acknowledges support by the Max Planck ETH Center for Learning Systems.This is the author accepted manuscript. The final version is available from Nature Publishing Group via http://dx.doi.org/10.1038/nmat456

Magnetic microrobot and its application in a microfluidic system

AbstractThis paper researches the design and control method of a microrobot in a microfluidic system by electromagnetic field. The microrobot can move along the microchannel to a required position, and by changing the magnetic torque, the microrobot can also rotate in the microfluidic chip. As an application of the microrobot, it is used as a mobile micromixer to mix two solutions in the microfluidic chip, and the experimental results verify its effectiveness

Design and Simulation of a Novel Magnetic Microactuator for Microrobots in Lab-On-a-Chip Applications

This article presents the design of a magnetic microactuator comprising soft magnetic material blocks and flexible beams. The modular layout of the proposed microactuator promotes scalability towards different microrobotic applications using low magnetic fields.  The presented microactuator consists of three soft magnetic material (Ni-Fe 4750) blocks connected together via two Polydimethylsiloxane (PDMS) semi-circular beams. A detailed design approach is highlighted giving considerations toward compactness, range of motion and force characteristics of the actuator. The actuator displacement and force characteristics are approximately linear in the magnetic field strength range of 80-160 kA/m. It can achieve maximum displacements of 111.6 µm (at 160 kA/m) during extension and 10.7 µm (at 80 kA/m) during contraction under no-load condition. The maximum force output of the microactuator, computed through a contact simulation, was 404.3 nN at a magnetic field strength of 160 kA/m. The microactuator achieved stroke angles up to 18.4 in a study where the microactuator was integrated with a swimming microrobot executing rowing motion using an artificial appendage, providing insight into the capabilities of actuating untethered microrobots

First experiments on MagPieR: a planar wireless magnetic and piezoelectric microrobot.

International audienceThe paper documents the principle and experiments of the "2mm dash" winner at NIST IEEE Mobile Microrobotics Challenge held at ICRA2010 in Alaska [1]. Submission is made for the special session "ICRA Robot Challenge: Advancing Research Through Competitions". The new MagPieR microrobot was specially designed for breaking the speed record, providing a planar magnetic actuation with an optimised coils setup and a subsequent piezoelectric actuation for improved sliding condition. The paper describes the principle of actuation, the microrobot manufacturing flowchart and the assembly setup. Some simulations are provided with a first series of experimental data and conclusions

Doctor of Philosophy

dissertationThis dissertation presents results documenting advancements on the control of untethered magnetic devices, such as magnetic \microrobots" and magnetically actuated capsuleendoscopes, motivated by problems in minimally invasive medicine. This dissertationfocuses on applying rotating magnetic elds for magnetic manipulation. The contributions include advancements in the way that helical microswimmers (devices that mimicthe propulsion of bacterial agella) are controlled in the presence of gravitational forces, advancements in ways that groups of untethered magnetic devices can be dierentiated and semi-independently controlled, advancements in the way that untethered magnetic device can be controlled with a single rotating permanent magnet, and an improved understanding in the nature of the magnetic force applied to an untethered device by a rotating magnet

FABRICATION OF MAGNETIC TWO-DIMENSIONAL AND THREE-DIMENSIONAL MICROSTRUCTURES FOR MICROFLUIDICS AND MICROROBOTICS APPLICATIONS

Micro-electro-mechanical systems (MEMS) technology has had an increasing impact on industry and our society. A wide range of MEMS devices are used in every aspects of our life, from microaccelerators and microgyroscopes to microscale drug-delivery systems. The increasing complexity of microsystems demands diverse microfabrication methods and actuation strategies to realize. Currently, it is challenging for existing microfabrication methods—particularly 3D microfabrication methods—to integrate multiple materials into the same component. This is a particular challenge for some applications, such as microrobotics and microfluidics, where integration of magnetically-responsive materials would be beneficial, because it enables contact-free actuation. In addition, most existing microfabrication methods can only fabricate flat, layered geometries; the few that can fabricate real 3D microstructures are not cost efficient and cannot realize mass production. This dissertation explores two solutions to these microfabrication problems: first, a method for integrating magnetically responsive regions into microstructures using photolithography, and second, a method for creating three-dimensional freestanding microstructures using a modified micromolding technique. The first method is a facile method of producing inexpensive freestanding photopatternable polymer micromagnets composed NdFeB microparticles dispersed in SU-8 photoresist. The microfabrication process is capable of fabricating polymer micromagnets with 3 µm feature resolution and greater than 10:1 aspect ratio. This method was used to demonstrate the creation of freestanding microrobots with an encapsulated magnetic core. A magnetic control system was developed and the magnetic microrobots were moved along a desired path at an average speed of 1.7 mm/s in a fluid environment under the presence of external magnetic field. A microfabrication process using aligned mask micromolding and soft lithography was also developed for creating freestanding microstructures with true 3D geometry. Characterization of this method and resolution limits were demonstrated. The combination of these two microfabrication methods has great potential for integrating several material types into one microstructure for a variety of applications

Challenges in flexible microsystem manufacturing : fabrication, robotic assembly, control, and packaging.

Microsystems have been investigated with renewed interest for the last three decades because of the emerging development of microelectromechanical system (MEMS) technology and the advancement of nanotechnology. The applications of microrobots and distributed sensors have the potential to revolutionize micro and nano manufacturing and have other important health applications for drug delivery and minimal invasive surgery. A class of microrobots studied in this thesis, such as the Solid Articulated Four Axis Microrobot (sAFAM) are driven by MEMS actuators, transmissions, and end-effectors realized by 3-Dimensional MEMS assembly. Another class of microrobots studied here, like those competing in the annual IEEE Mobile Microrobot Challenge event (MMC) are untethered and driven by external fields, such as magnetic fields generated by a focused permanent magnet. A third class of microsystems studied in this thesis includes distributed MEMS pressure sensors for robotic skin applications that are manufactured in the cleanroom and packaged in our lab. In this thesis, we discuss typical challenges associated with the fabrication, robotic assembly and packaging of these microsystems. For sAFAM we discuss challenges arising from pick and place manipulation under microscopic closed-loop control, as well as bonding and attachment of silicon MEMS microparts. For MMC, we discuss challenges arising from cooperative manipulation of microparts that advance the capabilities of magnetic micro-agents. Custom microrobotic hardware configured and demonstrated during this research (such as the NeXus microassembly station) include micro-positioners, microscopes, and controllers driven via LabVIEW. Finally, we also discuss challenges arising in distributed sensor manufacturing. We describe sensor fabrication steps using clean-room techniques on Kapton flexible substrates, and present results of lamination, interconnection and testing of such sensors are presented

Design and Implementation of Electromagnetic Actuation System to Actuate Micro/NanoRobots in Viscous Environment

The navigation of Micro/Nanorobots (MNRs) with the ability to track a selected trajectory accurately holds significant promise for different applications in biomedicine, providing methods for diagnoses and treatments inside the human body. The critical challenge is ensuring that the required power can be generated within the MNR. Furthermore, ensuring that it is feasible for the robot to travel inside the human body with the necessary power availability. Currently, MNRs are widely driven either by exogenous power sources (light energy, magnetic fields, electric fields, acoustics fields, etc.) or by endogenous energy sources, such as chemical interaction energy. Various driving techniques have been established, including piezoelectric as a driving source, thermal driving, electro-osmotic force driven by biological bacteria, and micro-motors powered by chemical fuel. These driving techniques have some restrictions, mainly when used in biomedicine. External magnetic fields are another potential power source of MNRs. Magnetic fields can permeate deep tissues and be safe for human organisms. As a result, magnetic fields’ magnetic forces and moments can be applied to MNRs without affecting biological fluids and tissues. Due to their features and characteristics of magnetic fields in generating high power, they are naturally suited to control the electromagnetically actuated MNRs in inaccessible locations due to their ability to go through tiny spaces. From the literature, it can be inferred from the available range of actuation technologies that magnetic actuation performs better than other technologies in terms of controllability, speed, flexibility of the working environment, and far less harm may cause to people. Also, electromagnetic actuation systems may come in various configurations that offer many degrees of freedom, different working mediums, and controllability schemes. Although this is a promising field of research, further simulation studies, and analysis, new smart materials, and the development and building of new real systems physically, and testing the concepts under development from different aspects and application requirements are required to determine whether these systems could be implemented in natural clinical settings on the human body. Also, to understand the latest development in MNRs and the actuation techniques with the associated technologies. Also, there is a need to conduct studies and comparisons to conclude the main research achievements in the field, highlight the critical challenges waiting for answers, and develop new research directions to solve and improve the performance. Therefore, this thesis aims to model and analyze, simulate, design, develop, and implement (with complete hardware and software integration) an electromagnetic actuation (EMA) system to actuate MNRs in the sixdimensional (6D) motion space inside a relatively large region of interest (ROI). The second stage is a simulation; simulation and finite element analysis were conducted. COMSOL multi-physics software is used to analyze the performance of different coils and coil pairs for Helmholtz and Maxwell coil configurations and electromagnetic actuation systems. This leads to the following.: • Finite element analysis (FEA) demonstrates that the Helmholtz coils generate a uniform and consistent magnetic field within a targeted ROI, and the Maxwell coils generate a uniform magnetic gradient. • The possibility to combine Helmholtz and Maxwell coils in different space dimensions. With the ability to actuate an MNR in a 6D space: 3D as a position and 3D as orientation. • Different electromagnetic system configurations are proposed, and their effectiveness in guiding an MNR inside a mimicked blood vessel environment was assessed. • Three pairs of Helmholtz coils and three pairs of coils of Maxwell coils are combined to actuate different size MNRs inside a mimicked blood vessel environment and in 6D. Based on the modeling results, a magnetic actuation system prototype that can control different sizes MNRs was conceived. A closed-loop control algorithm was proposed, and motion analysis of the MNR was conducted and discussed for both position and orientation. Improved EMA location tracking along a chosen trajectory was achieved using a PID-based closed-loop control approach with the best possible parameters. Through the model and analysis stage, the developed system was simulated and tested using open- and closed-loop circumstances. Finally, the closedloop controlled system was concluded and simulated to verify the ability of the proposed EMA to actuate an MN under different trajectory tracking examples with different dimensionality and for different sizes of MNRs. The last stage is developing the experimental setup by manufacturing the coils and their base in-house. Drivers and power supplies are selected according to the specifications that actuate the coils to generate the required magnetic field. Three digital microscopes were integrated with the electromagnetic actuation system to deliver visual feedback aiming to track in real-time the location of the MNR in the 6D high viscous fluidic environment, which leads to enabling closed-loop control. The closed-loop control algorithm is developed to facilitate MNR trajectory tracking and minimize the error accordingly. Accordingly, different tests were carried out to check the uniformity of the magnetic field generated from the coils. Also, a test was done for the digital microscope to check that it was calibrated and it works correctly. Experimental tests were conducted in 1D, 2D plane, and 3D trajectories with two different MNR sizes. The results show the ability of the proposed EMA system to actuate the two different sizes with a tracking error of 20-45 µm depending on the axis and the size of the MNR. The experiments show the ability of the developed EMA system to hold the MNR at any point within the 3D fluidic environment while overcoming the gravity effects. A comparison was made between the results achieved (in simulation and physical experiments) and the results deduced from the literature. The comparison shows that the thesis’s outcomes regarding the error and MNR size used are significant, with better performance relative to the MNR size and value of the error